CymitQuimica logo
Endocrinologie/Hormones

Endocrinologie/Hormones

Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.

Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"

Affichez 6 plus de sous-catégories

3269 produits trouvés pour "Endocrinologie/Hormones"

Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
produits par page.
  • CO23
    Targetmol
    + Info

    CO23

    CAS :
    <p>CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.</p>
    Formule :C19H18I2N2O4
    Degré de pureté :98.08%
    Couleur et forme :Solid
    Masse moléculaire :592.17

    Ref: TM-T10855

  • Ranirestat
    Targetmol
    + Info

    Ranirestat

    CAS :
    Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathy
    Formule :C17H11BrFN3O4
    Degré de pureté :96.10% - 99.44%
    Couleur et forme :Solid
    Masse moléculaire :420.19

    Ref: TM-T16723

  • Rovatirelin
    Targetmol
    + Info

    Rovatirelin

    CAS :
    <p>Rovatirelin (S-0373) is a TRH analog that improves motor dysfunction in a rat model of cytosine arabinoside-induced spinal cerebellar degeneration.</p>
    Formule :C16H22N4O4S
    Degré de pureté :99.59%
    Couleur et forme :Solid
    Masse moléculaire :366.43

    Ref: TM-T34399

  • MB-07811
    Targetmol
    + Info

    MB-07811

    CAS :
    <p>MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.</p>
    Formule :C28H32ClO5P
    Degré de pureté :99.74% - 99.94%
    Couleur et forme :Solid
    Masse moléculaire :514.98

    Ref: TM-T16018

  • DS08210767
    Targetmol
    + Info

    DS08210767

    CAS :
    <p>DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.</p>
    Formule :C31H39N5O2
    Degré de pureté :98.79%
    Couleur et forme :Solid
    Masse moléculaire :513.67

    Ref: TM-T11101

  • AMG 837 calcium hydrate
    Targetmol
    + Info

    AMG 837 calcium hydrate

    CAS :
    <p>AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM.</p>
    Formule :C52H44CaF6O8
    Degré de pureté :98.07%
    Couleur et forme :Solid
    Masse moléculaire :950.97

    Ref: TM-TQ0020

  • Metahexestrol
    Targetmol
    + Info

    Metahexestrol

    CAS :
    <p>Metahexestrol is an inhibitor of the estrogen receptor (E2R) with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cell line with an ED50 of 1.0 μM. Additionally, Metahexestrol shows inhibitory activity in estrogen receptor-negative MDA-MB-231 cell lines, and its antiproliferative effect is not reversed by estrogen, suggesting that its mechanism may be partially independent of the E2R pathway. Metahexestrol is applicable in research on estrogen-dependent breast cancer.</p>
    Formule :C18H22O2
    Couleur et forme :Solid
    Masse moléculaire :270.366

    Ref: TM-T206528

  • Norbinaltorphimine dihydrochloride
    Targetmol
    + Info

    Norbinaltorphimine dihydrochloride

    CAS :
    <p>Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.</p>
    Formule :C40H45Cl2N3O6
    Degré de pureté :98.17% - 99.88%
    Couleur et forme :Solid
    Masse moléculaire :734.71

    Ref: TM-T12241

  • SB-612111
    Targetmol
    + Info

    SB-612111

    CAS :
    SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.
    Formule :C24H29Cl2NO
    Couleur et forme :Solid
    Masse moléculaire :418.40

    Ref: TM-T36376

  • JTP-117968
    Targetmol
    + Info

    JTP-117968

    CAS :
    JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.
    Formule :C31H31F3N2O2
    Couleur et forme :Solid
    Masse moléculaire :520.59

    Ref: TM-T63636

  • 21-Deacetoxy deflazacort
    Targetmol
    + Info

    21-Deacetoxy deflazacort

    CAS :
    <p>21-Deacetoxy deflazacort is a dehydrogenated derivative of Deflazacort, which is a glucocorticoid. As an inactive precursor, Deflazacort rapidly converts into the active metabolite, 21-Desacetyldeflazacort. This compound serves as both an anti-inflammatory and immunosuppressive agent.</p>
    Formule :C23H29NO4
    Couleur et forme :Solid
    Masse moléculaire :383.48

    Ref: TM-T201719

  • FL442
    Targetmol
    + Info

    FL442

    CAS :
    <p>FL442 is an Androgen Receptor (AR) modulator. This compound exhibits potent inhibitory effects in AR-dependent prostate cancer cells, showing similar suppression efficiency to the traditional antiandrogen drugs Bicalutamide and Enzalutamide. It also maintains antiandrogen activity against the Enzalutamide-resistant AR mutant F876L. The pharmacokinetic properties of FL442 in mice reveal a longer half-life (8 hours), excellent targeting (prostate tissue), and metabolic stability. Additionally, it is effective at inhibiting LNCaP tumor growth at low plasma concentrations (30 ng/mL).</p>
    Formule :C15H13F3N2O
    Couleur et forme :Solid
    Masse moléculaire :294.27

    Ref: TM-T200138

  • Androgen receptor antagonist 12
    Targetmol
    + Info

    Androgen receptor antagonist 12

    CAS :
    Compound EF2 (Androgen receptor antagonist 12) is an orally active antagonist of the androgen receptor (AR) with an IC50 of 0.30 µM. It inhibits the transcriptional activity of mutant AR and the proliferation of AR-positive PCa (prostate cancer) cell lines. Additionally, Compound EF2 blocks the nuclear translocation of AR and suppresses tumor growth in the C4-2B xenograft mouse model. This compound is used for research in prostate cancer.
    Formule :C12H8F3N3O2
    Couleur et forme :Solid
    Masse moléculaire :283.21

    Ref: TM-T201604

  • Estrogen receptor-agonist-1
    Targetmol
    + Info

    Estrogen receptor-agonist-1

    CAS :
    Estrogen receptor-agonist-1 (compound 4e) is an estrogen receptor (ER) agonist that binds to ERα with high affinity.
    Formule :C24H22N2O2
    Couleur et forme :Solid
    Masse moléculaire :370.444

    Ref: TM-T204741

  • Triisopropyl phosphate
    Targetmol
    + Info

    Triisopropyl phosphate

    CAS :
    Triisopropyl phosphate inhibits TFF1 and EGR3 gene expression and exhibits anti-estrogenic activity by suppressing Estradiol-induced proliferation of MCF-7 cells, with an EC50 of 341 μM. Additionally, Triisopropyl phosphate reduces estrogen response element (ERE)-stimulated luciferase activity in MVLN cells, with an EC50 of 900 μM.
    Formule :C9H21O4P
    Couleur et forme :Solid
    Masse moléculaire :224.234

    Ref: TM-T205125

  • GC 14
    Targetmol
    + Info

    GC 14

    CAS :
    GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.
    Formule :C26H27NO6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :449.5

    Ref: TM-T11376

  • Androgen receptor antagonist 11
    Targetmol
    + Info

    Androgen receptor antagonist 11

    CAS :
    Androgen receptor antagonist 11 (compound N29) is a selective, orally available antagonist.
    Formule :C20H19F3N4O3S
    Couleur et forme :Solid
    Masse moléculaire :452.45

    Ref: TM-T201269

  • Androgen receptor degrader-5
    Targetmol
    + Info

    Androgen receptor degrader-5

    CAS :
    <p>Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.</p>
    Formule :C29H25F4N5O2
    Couleur et forme :Solid
    Masse moléculaire :551.53

    Ref: TM-T200197

  • LIT-001 free base
    Targetmol
    + Info

    LIT-001 free base

    CAS :
    <p>LIT-001, a nonpeptide OT-R agonist, enhances mouse autism-like behavior, with EC50=55 nM and Ki=226 nM.</p>
    Formule :C28H33N7O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :531.67

    Ref: TM-T11856

  • MLS000389544
    Targetmol
    + Info

    MLS000389544

    CAS :
    MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).
    Formule :C20H24N2O7S
    Couleur et forme :Solid
    Masse moléculaire :436.479

    Ref: TM-T204954