Récepteur des androgènes
Le récepteur aux androgènes (AR) est un récepteur hormonal nucléaire activé par la liaison aux androgènes, tels que la testostérone et la dihydrotestostérone. Ce récepteur joue un rôle crucial dans le développement et le maintien des caractéristiques masculines, ainsi que dans la régulation de plusieurs processus physiologiques, notamment la croissance musculaire, la libido et la densité osseuse. Les inhibiteurs du récepteur aux androgènes sont largement étudiés dans le contexte du cancer de la prostate, où la signalisation de l'AR est souvent régulée à la hausse. Chez CymitQuimica, nous offrons une gamme de modulateurs du récepteur aux androgènes de haute qualité pour soutenir vos recherches en endocrinologie, biologie du cancer et régulation hormonale.
207 produits trouvés pour "Récepteur des androgènes"
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Zanoterone
CAS :<p>Zanoterone is an AR antagonist (androgen receptor).Zanoterone has antitumor activity for the treatment of genitourinary disorders and oncological disorders and</p>Formule :C23H32N2O3SDegré de pureté :99.03% - 99.92%Couleur et forme :SoildMasse moléculaire :416.58Spironolactone
CAS :<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Formule :C24H32O4SDegré de pureté :99.87%Couleur et forme :White PowderMasse moléculaire :416.573,3'-Diindolylmethane
CAS :<p>3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.</p>Formule :C17H14N2Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :246.31Luxdegalutamide
CAS :<p>Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the</p>Formule :C45H54FN7O6Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :807.95Cyproterone acetate
CAS :<p>Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and</p>Formule :C24H29ClO4Degré de pureté :98.43% - 99.83%Couleur et forme :Crystals From Diisopropyl Ether OdourMasse moléculaire :416.94Ostarine
CAS :<p>Ostarine (MK-2866) is a non-steroidal SARM mimicking testosterone to boost muscle growth, libido, fertility, and may help prevent muscle wasting in cancer.</p>Formule :C19H14F3N3O3Degré de pureté :99.69% - 99.90%Couleur et forme :SolidMasse moléculaire :389.33Adrenocorticotropic hormone TFA
<p>Adrenocorticotropic hormone TFA is an adrenocorticotropic hormone involved in neurohormonal regulation of the body.</p>Degré de pureté :99.71%Couleur et forme :Odour SolidOctinoxate
CAS :<p>Octinoxate (Octyl 4-methoxycinnamate) is an organic compound that is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun.</p>Formule :C18H26O3Degré de pureté :99.93%Couleur et forme :Less To Pale Yellow Viscous Liquid (Ntp 1992) Physical Description Colorless To Pale Yellow Viscous Liquid (Ntp 1992)Masse moléculaire :290.40BWA-6047
<p>BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.</p>Formule :C42H46ClN5O7Couleur et forme :SolidMasse moléculaire :767.30858Nuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Couleur et forme :Odour SolidDipropyl phthalate
CAS :<p>Dipropyl phthalate is a weak androgen receptor inhibitor, and can be used in biochemical experiments and drug synthesis.</p>Formule :C14H18O4Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :250.292-sec-Butylphenol
CAS :<p>2-sec-Butylphenol is an inhibitor of the androgen receptor and P450 aromatase, and can be used in research and experiments in the field of life sciences.</p>Formule :C10H14OCouleur et forme :SolidMasse moléculaire :150.22ARD-2585
CAS :<p>ARD-2585 is an orally active and selective androgen receptor PROTAC degrader with anticancer activity for the study of prostate cancer.</p>Formule :C41H43ClN8O5Couleur et forme :SolidMasse moléculaire :763.28Faznolutamide
CAS :<p>Faznolutamide is an antiandrogen agent [1] [2] .</p>Formule :C19H17FN4O2SCouleur et forme :SolidMasse moléculaire :384.43Inocoterone acetate
CAS :<p>Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.</p>Formule :C18H26O3Couleur et forme :SolidMasse moléculaire :290.40PROTAC AR Degrader-8
CAS :<p>PROTAC AR Degrader-8 (Compound NP18) functions as a PROTAC degrader targeting the androgen receptor (AR) and effectively degrades AR-FL in both 22Rv1 and LNCaP cells with DC50 values of 0.018 μM and 0.14 μM, respectively. It also degrades AR-V7 in 22Rv1 cells with a DC50 of 0.026 μM. Additionally, PROTAC AR Degrader-8 inhibits the proliferation of 22Rv1 and LNCaP cancer cells, exhibiting IC50 values of 0.038 μM and 1.11 μM. It induces cell cycle arrest at the G2/M phase and triggers apoptosis in 22Rv1 cells (apoptosis). Demonstrating anticancer efficacy, PROTAC AR Degrader-8 shows activity in both mouse and zebrafish models. [Pink: ligand for target protein AR ligand-33; Black: linker; Blue: ligand for E3 ligase Cereblon]</p>Formule :C40H41N5O7Couleur et forme :SolidMasse moléculaire :703.783MTX-23
CAS :<p>MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the proliferation of CaP cells and inducing</p>Formule :C43H53F2N7O7S2Couleur et forme :SolidMasse moléculaire :882.0511-Ketodihydrotestosterone
CAS :<p>11-Ketodihydrotestosterone is a metabolite of 11β-Hydroxyandrostenedione. It is an active androgen and is also a potent androgen receptor (AR) agonist (Ki: 20.4 nM, EC50: 1.35 nM for human AR).</p>Formule :C19H28O3Couleur et forme :SolidMasse moléculaire :304.42ODM-204
CAS :<p>ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).</p>Formule :C20H21F3N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.40PROTAC AR Degrader-4 TFA
<p>PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.</p>Formule :C45H68F3N3O11Couleur et forme :SolidMasse moléculaire :884.03
