Ras
Les protéines Ras sont de petites GTPases qui agissent comme des commutateurs moléculaires dans la voie de signalisation MAPK, contrôlant la croissance, la différenciation et la survie cellulaires. Ras activé initie une cascade de signalisation qui inclut Raf, MEK et ERK, conduisant à diverses réponses cellulaires. Les mutations des gènes Ras sont courantes dans les cancers, faisant de Ras un point focal important de la recherche sur le cancer. Chez CymitQuimica, nous offrons une gamme de modulateurs de Ras pour soutenir vos recherches en biologie du cancer, transduction de signaux et développement thérapeutique.
154 produits trouvés pour "Ras"
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Lonafarnib
CAS :Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formule :C27H31Br2ClN4O2Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :638.82ML-098
CAS :ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).Formule :C19H19NO3Degré de pureté :99.06% - 99.23%Couleur et forme :SolidMasse moléculaire :309.36Ref: TM-T4619
1mg37,00€2mg50,00€5mg66,00€10mg94,00€25mg190,00€50mg268,00€100mg374,00€500mg884,00€1mL*10mM (DMSO)84,00€MRTX1133
CAS :View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Formule :C33H31F3N6O2Degré de pureté :97.39% - 99.6%Couleur et forme :SolidMasse moléculaire :600.63Ref: TM-T9303
1mg177,00€5mg379,00€10mg580,00€25mg893,00€50mg1.251,00€100mg1.639,00€200mg2.215,00€1mL*10mM (DMSO)502,00€K-Ras-IN-1
CAS :K-Ras-IN-1 is a K-Ras inhibitor.Formule :C11H13NOSDegré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :207.29APS6-45
CAS :APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Formule :C23H16F8N4O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :548.39Ref: TM-T8843
2mg37,00€5mg84,00€10mg120,00€25mg236,00€50mg380,00€100mg583,00€200mg785,00€1mL*10mM (DMSO)92,00€Eicosapentaenoic Acid
CAS :Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). High-Quality, Low-Cost!Formule :C20H30O2Degré de pureté :97.03% - 99.83%Couleur et forme :LiquidMasse moléculaire :302.45SCH54292
CAS :SCH-54292 is a GDP exchange inhibitor.Formule :C24H28N2O9SDegré de pureté :95.65%Couleur et forme :SolidMasse moléculaire :520.55ZT-12-037-01
CAS :Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Formule :C21H31N5O2Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :385.5CID44216842
CAS :CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formule :C22H20BrN3O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.38Ref: TM-T8930
2mg34,00€5mg50,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€1mL*10mM (DMSO)55,00€KRAS inhibitor-9
CAS :KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formule :C13H9ClN2S2Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :292.81Ref: TM-T8756
1mg57,00€2mg81,00€5mg113,00€10mg178,00€25mg334,00€50mg485,00€100mg622,00€1mL*10mM (DMSO)136,00€CCG-100602
CAS :CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formule :C21H17ClF6N2O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :478.82Ref: TM-T22062
5mg35,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€1mL*10mM (DMSO)40,00€Sotorasib
CAS :Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.Formule :C30H30F2N6O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :560.594Ref: TM-T8684
1g1.359,00€1mg37,00€2mg52,00€5mg79,00€10mg126,00€25mg225,00€50mg374,00€100mg459,00€500mg1.026,00€1mL*10mM (DMSO)87,00€BAY-293
CAS :BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).Formule :C25H28N4O2SDegré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :448.58Ref: TM-T5418
1mg50,00€5mg105,00€10mg177,00€25mg321,00€50mg482,00€100mg710,00€200mg982,00€1mL*10mM (DMSO)116,00€BQU57
CAS :BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formule :C16H13F3N4ODegré de pureté :97.45% - 98.72%Couleur et forme :SolidMasse moléculaire :334.3Arglabin
CAS :Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formule :C15H18O3Degré de pureté :98.97% - 99.62%Couleur et forme :SolidMasse moléculaire :246.3Ref: TM-TQ0165
1mg84,00€2mg123,00€5mg227,00€10mg341,00€25mg492,00€50mg655,00€100mg982,00€200mg1.314,00€1mL*10mM (DMSO)294,00€Kobe2602
CAS :Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formule :C14H9F4N5O4SDegré de pureté :98.36% - 99.39%Couleur et forme :SolidMasse moléculaire :419.31(Rac)-Antineoplaston A10
CAS :Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Formule :C13H14N2O3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :246.26Ref: TM-T5379
1mg38,00€5mg84,00€10mg122,00€25mg198,00€50mg295,00€100mg424,00€200mg593,00€1mL*10mM (DMSO)90,00€Salirasib
CAS :Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formule :C22H30O2SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :358.54Ref: TM-T6163
5mg34,00€10mg50,00€25mg90,00€50mg150,00€100mg210,00€200mg344,00€500mg567,00€1mL*10mM (DMSO)56,00€ML-097
CAS :ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormule :C14H11BrO3Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :307.139Ref: TM-T21970
5mg62,00€10mg90,00€25mg133,00€50mg192,00€100mg286,00€500mg687,00€1mL*10mM (DMSO)67,00€ZCL278
CAS :ZCL278 is a selective Cdc42 GTPase inhibitor.Formule :C21H19BrClN5O4S2Degré de pureté :96.29% - 99.72%Couleur et forme :SolidMasse moléculaire :584.89Ref: TM-T1855
5mg52,00€10mg74,00€25mg129,00€50mg210,00€100mg294,00€200mg470,00€500mg763,00€1mL*10mM (DMSO)74,00€
