Ras
Les protéines Ras sont de petites GTPases qui agissent comme des commutateurs moléculaires dans la voie de signalisation MAPK, contrôlant la croissance, la différenciation et la survie cellulaires. Ras activé initie une cascade de signalisation qui inclut Raf, MEK et ERK, conduisant à diverses réponses cellulaires. Les mutations des gènes Ras sont courantes dans les cancers, faisant de Ras un point focal important de la recherche sur le cancer. Chez CymitQuimica, nous offrons une gamme de modulateurs de Ras pour soutenir vos recherches en biologie du cancer, transduction de signaux et développement thérapeutique.
154 produits trouvés pour "Ras"
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EHT 1864 2HCl
CAS :EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formule :C25H29Cl2F3N2O4SDegré de pureté :98.39% - 99.42%Couleur et forme :SolidMasse moléculaire :581.47Kobe0065
CAS :Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Formule :C15H11ClF3N5O4SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :449.79Oncrasin-1
CAS :Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormule :C16H12ClNODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :269.73FTI-277 hydrochloride
CAS :FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Formule :C22H30ClN3O3S2Degré de pureté :97.57% - 97.61%Couleur et forme :SolidMasse moléculaire :484.07Ref: TM-T2700
1mg50,00€2mg70,00€5mg90,00€10mg158,00€25mg304,00€50mg497,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)102,00€(S)-AMG-510
CAS :(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.Formule :C30H30F2N6O3Degré de pureté :99.05% - 99.76%Couleur et forme :SolidMasse moléculaire :560.594Ref: TM-T22258
2mg34,00€5mg50,00€10mg80,00€25mg147,00€50mg259,00€100mg404,00€500mg888,00€1mL*10mM (DMSO)73,00€K-Ras(G12C) inhibitor 12
CAS :K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formule :C15H17ClIN3O3Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :449.67ERK-IN-3
CAS :ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.Formule :C22H25ClFN7O2Degré de pureté :99.55% - 99.76%Couleur et forme :SolidMasse moléculaire :473.93ASP2453
CAS :ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Formule :C40H48F3N7O4Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :747.85CCG-1423
CAS :CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formule :C18H13ClF6N2O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :454.75Ref: TM-T2014
5mg35,00€10mg54,00€25mg90,00€50mg154,00€100mg248,00€200mg385,00€500mg625,00€1mL*10mM (DMSO)52,00€6H05 (TFA)
CAS :6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.Formule :C22H31ClF3N3O4S3Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :590.14Ref: TM-T7326
1mg65,00€2mg90,00€5mg127,00€10mg217,00€25mg358,00€50mg538,00€100mg765,00€1mL*10mM (DMSO)166,00€Lonafarnib
CAS :Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formule :C27H31Br2ClN4O2Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :638.82ML-098
CAS :ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).Formule :C19H19NO3Degré de pureté :99.06% - 99.23%Couleur et forme :SolidMasse moléculaire :309.36Ref: TM-T4619
1mg37,00€2mg50,00€5mg66,00€10mg94,00€25mg190,00€50mg268,00€100mg374,00€500mg884,00€1mL*10mM (DMSO)84,00€MRTX1133
CAS :View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Formule :C33H31F3N6O2Degré de pureté :97.39% - 99.6%Couleur et forme :SolidMasse moléculaire :600.63Ref: TM-T9303
1mg177,00€5mg379,00€10mg580,00€25mg893,00€50mg1.251,00€100mg1.639,00€200mg2.215,00€1mL*10mM (DMSO)502,00€K-Ras-IN-1
CAS :K-Ras-IN-1 is a K-Ras inhibitor.Formule :C11H13NOSDegré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :207.29APS6-45
CAS :APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Formule :C23H16F8N4O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :548.39Ref: TM-T8843
2mg37,00€5mg84,00€10mg120,00€25mg236,00€50mg380,00€100mg583,00€200mg785,00€1mL*10mM (DMSO)92,00€Eicosapentaenoic Acid
CAS :Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). High-Quality, Low-Cost!Formule :C20H30O2Degré de pureté :97.03% - 99.83%Couleur et forme :LiquidMasse moléculaire :302.45SCH54292
CAS :SCH-54292 is a GDP exchange inhibitor.Formule :C24H28N2O9SDegré de pureté :95.65%Couleur et forme :SolidMasse moléculaire :520.55ZT-12-037-01
CAS :Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Formule :C21H31N5O2Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :385.5CID44216842
CAS :CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formule :C22H20BrN3O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.38Ref: TM-T8930
2mg34,00€5mg50,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€1mL*10mM (DMSO)55,00€KRAS inhibitor-9
CAS :KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formule :C13H9ClN2S2Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :292.81Ref: TM-T8756
1mg57,00€2mg81,00€5mg113,00€10mg178,00€25mg334,00€50mg485,00€100mg622,00€1mL*10mM (DMSO)136,00€CCG-100602
CAS :CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formule :C21H17ClF6N2O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :478.82Ref: TM-T22062
5mg35,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€1mL*10mM (DMSO)40,00€Sotorasib
CAS :Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.Formule :C30H30F2N6O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :560.594Ref: TM-T8684
1g1.359,00€1mg37,00€2mg52,00€5mg79,00€10mg126,00€25mg225,00€50mg374,00€100mg459,00€500mg1.026,00€1mL*10mM (DMSO)87,00€BAY-293
CAS :BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).Formule :C25H28N4O2SDegré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :448.58Ref: TM-T5418
1mg50,00€5mg105,00€10mg177,00€25mg321,00€50mg482,00€100mg710,00€200mg982,00€1mL*10mM (DMSO)116,00€BQU57
CAS :BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formule :C16H13F3N4ODegré de pureté :97.45% - 98.72%Couleur et forme :SolidMasse moléculaire :334.3Arglabin
CAS :Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formule :C15H18O3Degré de pureté :98.97% - 99.62%Couleur et forme :SolidMasse moléculaire :246.3Ref: TM-TQ0165
1mg88,00€2mgÀ demander5mg240,00€10mg360,00€25mg518,00€50mg692,00€100mg1.035,00€200mg1.388,00€1mL*10mM (DMSO)310,00€Kobe2602
CAS :Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formule :C14H9F4N5O4SDegré de pureté :98.36% - 99.39%Couleur et forme :SolidMasse moléculaire :419.31(Rac)-Antineoplaston A10
CAS :Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Formule :C13H14N2O3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :246.26Ref: TM-T5379
1mg40,00€5mg88,00€10mg129,00€25mg210,00€50mg311,00€100mg449,00€200mg627,00€1mL*10mM (DMSO)95,00€Salirasib
CAS :Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formule :C22H30O2SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :358.54Ref: TM-T6163
5mg34,00€10mg50,00€25mg90,00€50mg150,00€100mg210,00€200mg344,00€500mg567,00€1mL*10mM (DMSO)56,00€ML-097
CAS :ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormule :C14H11BrO3Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :307.139Ref: TM-T21970
5mg62,00€10mg90,00€25mg133,00€50mg192,00€100mg286,00€500mg687,00€1mL*10mM (DMSO)67,00€ZCL278
CAS :ZCL278 is a selective Cdc42 GTPase inhibitor.Formule :C21H19BrClN5O4S2Degré de pureté :96.29% - 99.72%Couleur et forme :SolidMasse moléculaire :584.89Ref: TM-T1855
5mg52,00€10mg74,00€25mg129,00€50mg210,00€100mg294,00€200mg470,00€500mg763,00€1mL*10mM (DMSO)74,00€EHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :98.99% - >99.99%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg46,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€1mL*10mM (DMSO)49,00€1-(4-methansulfinylphenyl)ethanone
CAS :The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.Formule :C9H10O2SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :182.24Ref: TM-T8870
1mg49,00€5mg144,00€10mg195,00€25mg273,00€50mg383,00€100mg532,00€200mg718,00€1mL*10mM (DMSO)96,00€Rhosin hydrochloride
CAS :Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formule :C20H20Cl2N6ODegré de pureté :97.33% - 98.92%Couleur et forme :SolidMasse moléculaire :431.318Ref: TM-T16745
1mg159,00€2mg40,00€5mg58,00€10mg97,00€25mg216,00€50mg406,00€100mg735,00€1mL*10mM (DMSO)64,00€ARS-853
CAS :ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellsFormule :C22H29ClN4O3Degré de pureté :97.43% - 98.4%Couleur et forme :SolidMasse moléculaire :432.94Ref: TM-T7414
1mg142,00€5mg353,00€10mg525,00€25mg843,00€50mg1.144,00€100mg1.549,00€500mg3.087,00€1mL*10mM (DMSO)338,00€Antineoplaston A10
CAS :Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formule :C13H14N2O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :246.26Ref: TM-T7131
2mg44,00€5mg67,00€10mg103,00€25mg193,00€50mg295,00€100mg425,00€200mg595,00€1mL*10mM (DMSO)73,00€Phellodendrine chloride
CAS :Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formule :C20H24ClNO4Degré de pureté :98.85% - 99.05%Couleur et forme :SolidMasse moléculaire :377.86Ref: TM-T5S0777
5mg50,00€10mg71,00€25mg101,00€50mg150,00€100mg215,00€200mg318,00€1mL*10mM (DMSO)58,00€Y16
CAS :Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formule :C24H20N2O3Degré de pureté :98.26% - 99.85%Couleur et forme :SolidMasse moléculaire :384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€1mL*10mM (DMSO)77,00€NSC 23766 trihydrochloride
CAS :NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formule :C24H35N7·3HClDegré de pureté :96.48% - 99.54%Couleur et forme :SolidMasse moléculaire :530.96CID-1067700
CAS :CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formule :C18H18N2O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :390.48Ref: TM-T7558
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg178,00€50mg234,00€100mg303,00€1mL*10mM (DMSO)78,00€Z62954982
CAS :Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormule :C20H21N3O5SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :415.46Ref: TM-T37113
1mg38,00€5mg80,00€10mg111,00€25mg183,00€50mg269,00€100mg393,00€200mg560,00€1mL*10mM (DMSO)92,00€AZD0022
CAS :AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.Formule :C34H30F4N6ODegré de pureté :98.73%Couleur et forme :SoildMasse moléculaire :614.64Deltarasin
CAS :Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formule :C40H37N5ODegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :603.756H05
CAS :6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formule :C20H30ClN3O2S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.12MCP110
CAS :MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formule :C33H36N2O3Degré de pureté :97.23%Couleur et forme :OilMasse moléculaire :508.65Ref: TM-T24437
1mg34,00€5mg92,00€10mg160,00€25mg276,00€50mg400,00€100mg532,00€500mg1.063,00€1mL*10mM (DMSO)103,00€Digeranyl bisphosphonate
CAS :Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormule :C21H34Na4O6P2Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :536.4Methylophiopogonanone B
CAS :1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.Formule :C19H20O5Degré de pureté :99.24% - 99.83%Couleur et forme :SolidMasse moléculaire :328.36Ref: TM-T5S1261
1mg84,00€5mg178,00€10mg295,00€25mg497,00€50mg708,00€100mg964,00€200mg1.288,00€1mL*10mM (DMSO)192,00€KRAS inhibitor-7
CAS :KRAS inhibitor-7 is a potent KRAS G12C inhibitor.Formule :C26H27ClF2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.98KRas G12C inhibitor 3
CAS :KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.Formule :C32H36ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.13ESI-08
CAS :ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formule :C20H23N3OSDegré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :353.48KRAS inhibitor-6
CAS :KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formule :C27H30ClF2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.01
