CFTR
Le CFTR est une protéine canal chlorure qui régule le transport des ions chlorure et bicarbonate à travers les membranes des cellules épithéliales, jouant un rôle crucial dans le maintien de l'équilibre hydrique dans les tissus. Les mutations du gène CFTR entraînent la mucoviscidose, une maladie génétique caractérisée par la production de mucus épais pouvant obstruer les voies respiratoires et causer de graves problèmes respiratoires et digestifs. Chez CymitQuimica, nous proposons une sélection de modulateurs CFTR pour soutenir vos recherches sur la mucoviscidose, le transport des ions et les troubles génétiques.
66 produits trouvés pour "CFTR"
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Elexacaftor
CAS :Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Formule :C26H34F3N7O4SDegré de pureté :98.87% - 99.87%Couleur et forme :SolidMasse moléculaire :597.65Ref: TM-T14935
1mg93,00€2mg130,00€5mg230,00€10mg371,00€25mg730,00€50mg1.018,00€100mg1.369,00€1mL*10mM (DMSO)304,00€Glibenclamide
CAS :Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494.00(Rac)-Tezacaftor
CAS :(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.Formule :C26H27F3N2O6Couleur et forme :SolidMasse moléculaire :520.5kCAL01
CAS :kCAL01 is a CAL inhibitor with a Ki value of 2.3 μM and holds potential for research in cystic fibrosis (CF).Formule :C36H57N11O9Couleur et forme :SolidMasse moléculaire :787.91Crofelemer
CAS :Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Couleur et forme :SolidWAY-326766
CAS :WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formule :C21H23N3O5Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :397.42Vanzacaftor
CAS :Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.Formule :C32H39N7O4SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :617.76Astressin 2B
CAS :CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.Formule :C183H307N49O53Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4041.69(R)-Crinecerfont
CAS :4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomericFormule :C27H28ClFN2OSDegré de pureté :99.02%Couleur et forme :SoildMasse moléculaire :483.04Ref: TM-T60126
1mg109,00€2mg163,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mgÀ demander1mL*10mM (DMSO)289,00€H2-Gamendazole
CAS :H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Formule :C18H13Cl2F3N2O2Degré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :417.21Ref: TM-T72076
1mg73,00€5mg180,00€10mg269,00€25mg477,00€50mg642,00€100mg880,00€200mg1.161,00€1mL*10mM (DMSO)203,00€CFTR activator 2
CAS :CFTR activator 2 (WAY-326769) is an activator of mutant CFTR (cystic fibrosis transmembrane conductance regulator), which increases ion transport activity and can be used for research into cystic fibrosis (CF).Formule :C27H27N3O3Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :441.52Zatonacaftor
CAS :Zatonacaftor, a cystic fibrosis transmembrane regulator (CFTR) modulator, is utilized in the research of cystic fibrosis [1] [2].Formule :C24H27N3O4SCouleur et forme :SolidMasse moléculaire :453.55Cavosonstat
CAS :Cavosonstat (N91115) is an oral GSNOR inhibitor aiding CFTR in cystic fibrosis.Formule :C16H10ClNO3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :299.71CP-628006
CAS :CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.Formule :C32H35F3N2O2Couleur et forme :SolidMasse moléculaire :536.639Crinecerfont hydrochloride
CAS :SSR-125543, a potent CRF1 receptor non-peptide antagonist, effective in CAH research, taken orally.Formule :C27H29Cl2FN2OSCouleur et forme :SolidMasse moléculaire :519.5KM11060
CAS :KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormule :C19H17Cl2N3O2SDegré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :422.33Icenticaftor
CAS :Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.Formule :C12H13F6N3O3Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :361.24Ref: TM-T9499
1mg152,00€5mg313,00€10mg469,00€25mg750,00€50mg1.054,00€100mg1.494,00€200mg2.025,00€1mL*10mM (DMSO)248,00€Tezacaftor
CAS :Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formule :C26H27F3N2O6Degré de pureté :98.84% - >99.99%Couleur et forme :SolidMasse moléculaire :520.5Ref: TM-T2263
1mg40,00€2mg52,00€5mg82,00€10mg123,00€25mg212,00€50mg343,00€100mg505,00€1mL*10mM (DMSO)88,00€IOWH-032
CAS :IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formule :C22H15Br2N3O4Degré de pureté :98.92% - ≥95%Couleur et forme :SolidMasse moléculaire :545.18Ataluren
CAS :Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formule :C15H9FN2O3Degré de pureté :99.16% - 99.84%Couleur et forme :SolidMasse moléculaire :284.24Ref: TM-T1805
5mg35,00€10mg54,00€25mg88,00€50mg117,00€100mg178,00€200mg213,00€500mg359,00€1mL*10mM (DMSO)46,00€
