Canal chlorure
Les canaux chlorure sont des protéines membranaires qui contrôlent le mouvement des ions chlorure à travers les membranes cellulaires, jouant un rôle essentiel dans le maintien du volume cellulaire, de l'excitabilité électrique et de l'équilibre acido-basique. La dysrégulation des canaux chlorure est liée à des maladies telles que la mucoviscidose, l'épilepsie et les troubles rénaux. Chez CymitQuimica, nous proposons une variété de modulateurs des canaux chlorure pour soutenir vos recherches sur le transport des ions, l'homéostasie cellulaire et les mécanismes des maladies.
53 produits trouvés pour "Canal chlorure"
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Niflumic acid
CAS :<p>Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.</p>Formule :C13H9F3N2O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :282.22NS1652
CAS :<p>NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.</p>Formule :C15H11F3N2O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :324.25Eact
CAS :<p>Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.</p>Formule :C22H24N2O5SDegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :428.5Afoxolaner
CAS :Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.Formule :C26H17ClF9N3O3Degré de pureté :99.1% - 99.38%Couleur et forme :SolidMasse moléculaire :625.87Halothane
CAS :Halothane (Anestan) 可以减弱内皮依赖性舒张作用。Formule :C2HBrClF3Degré de pureté :99.80% - >99.99%Couleur et forme :Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustibleMasse moléculaire :197.38Endovion
CAS :Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker.Formule :C16H9BrF6N6ODegré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :495.18T16Ainh-A01
CAS :T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.Formule :C19H20N4O3S2Degré de pureté :97.18% - 98.15%Couleur et forme :SolidMasse moléculaire :416.52DCPIB
CAS :<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formule :C22H28Cl2O4Degré de pureté :99.79% - 99.87%Couleur et forme :SolidMasse moléculaire :427.36Flufenamic acid
CAS :<p>Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.</p>Formule :C14H10F3NO2Degré de pureté :98.68%Couleur et forme :White To Light Yellow Crystalline PowderMasse moléculaire :281.23Meticrane
CAS :Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.Formule :C10H13NO4S2Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :275.34Chlorotoxin(linear)
Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.Formule :C158H256N52O48S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4004.76ANO1-IN-4
CAS :ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.Formule :C19H19BrF2N2O2SCouleur et forme :SolidMasse moléculaire :457.33Chlorotoxin TFA
Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.Formule :C160H250F3N53O49S11Couleur et forme :SolidMasse moléculaire :4109.74Chlorotoxin
CAS :<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formule :C158H249N53O47S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3995.71GaTx2
CAS :High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formule :C125H199N39O47S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3192.54Umifoxolaner
CAS :Umifoxolaner is an anti-parasitic agent (veterinary).Formule :C26H16ClF10N3O3Couleur et forme :SolidMasse moléculaire :643.87Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Couleur et forme :Odour SolidLubiprostone hemiketal
CAS :Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.Formule :C20H32F2O5Couleur et forme :SolidMasse moléculaire :390.46Afoxolaner (Standard)
CAS :Afoxolaner (Standard) is the standard substance of Afoxolaner, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.Formule :C26H17ClF9N3O3Masse moléculaire :625.87Adjudin
CAS :Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Formule :C15H12Cl2N4ODegré de pureté :96.51% - ≥95%Couleur et forme :SolidMasse moléculaire :335.19
