Synthase des acides gras
La synthase des acides gras (FAS) est un complexe multi-enzymatique responsable de la synthèse des acides gras à longue chaîne. La surexpression de FAS est associée à divers troubles métaboliques, notamment l'obésité, le diabète et le cancer. L'inhibition de FAS peut réduire la biosynthèse des lipides et induire l'apoptose des cellules cancéreuses, ce qui en fait une cible prometteuse pour la thérapie contre le cancer et la recherche sur les maladies métaboliques. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de FAS pour soutenir vos recherches en oncologie, métabolisme et développement thérapeutique.
39 produits trouvés pour "Synthase des acides gras".
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trans-C75
CAS :trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).Formule :C14H22O4Degré de pureté :98.88% - 99.57%Couleur et forme :White To Off-White SolidMasse moléculaire :254.32Ref: TM-T10656
1mg49,00€2mg65,00€5mg90,00€1mL*10mM (DMSO)103,00€10mg152,00€25mg318,00€50mg509,00€100mg713,00€FASN-IN-3
CAS :FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).Formule :C24H24N4ODegré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :384.47Ref: TM-T11557
1mg46,00€5mg94,00€1mL*10mM (DMSO)103,00€10mg149,00€25mg245,00€50mg338,00€100mg480,00€200mg622,00€Denifanstat
CAS :Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.Formule :C27H29N5ODegré de pureté :98.33% - 99.35%Couleur et forme :SolidMasse moléculaire :439.55Ref: TM-T15271
1mg86,00€5mg177,00€1mL*10mM (DMSO)205,00€10mg299,00€25mg502,00€50mg710,00€100mg1.009,00€500mg2.008,00€PF429242 dihydrochloride
CAS :PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).Formule :C25H37Cl2N3O2Degré de pureté :99.68%Couleur et forme :White ViscousMasse moléculaire :482.49Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Couleur et forme :Odour SolidFASN-IN-4 tosylate
CAS :FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.Formule :C33H35N3O7S2Couleur et forme :SolidMasse moléculaire :649.78CTL-12
CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.Formule :C22H21ClN4O4Couleur et forme :SolidMasse moléculaire :440.88Fasnall HCl
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.Formule :C19H23ClN4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :374.93Ref: TM-T27307L
1mg90,00€5mg187,00€1mL*10mM (DMSO)210,00€10mg301,00€25mg477,00€50mg665,00€100mg897,00€200mg1.198,00€C75
CAS :C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).Formule :C14H22O4Degré de pureté :98.84% - >99.99%Couleur et forme :White SolidMasse moléculaire :254.32Ref: TM-T10657
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg154,00€25mg299,00€50mg477,00€100mg757,00€FASN/SCD-IN-1
FASN/SCD-IN-1 is a Silybin derivative and an orally active inhibitor of fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD). In vitro, FASN/SCD-IN-1 demonstrates the ability to inhibit lipid deposition, reduce the transcription levels of FASN and SCD, and exhibits antioxidant, anti-inflammatory, and antifibrotic activities. It shows significant hepatoprotective effects in rat models of acute liver injury and improves pathological features such as steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative-associated steatohepatitis (MASH). FASN/SCD-IN-1 can be used for MASH research.Couleur et forme :Odour SolidACSS2-IN-2
CAS :MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.Formule :C21H19F2N3O4Degré de pureté :99.5%Couleur et forme :SoildMasse moléculaire :415.39Ref: TM-T60060
1mg52,00€2mg77,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg334,00€50mg520,00€100mg750,00€IPI-9119
CAS :IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).Formule :C24H19F2N5O5Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :495.43Ref: TM-T36841
1mg92,00€5mg224,00€1mL*10mM (DMSO)243,00€10mg323,00€25mg515,00€50mg712,00€100mg964,00€200mg1.288,00€FASN Protein, Human, Recombinant (His)
FASN Protein, Human, Recombinant (His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :35.26 kDa (predicted)Ref: TM-TMPY-06683
5µg101,00€10µg166,00€20µg266,00€50µg540,00€100µg954,00€200µg1.665,00€500µg4.078,00€Anti-FASN Antibody (6U56)
Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.Couleur et forme :Odour LiquidGSK2194069
CAS :GSK2194069: Fatty acid synthase inhibitor, β-keto reductase-specific, IC50 7.7 nM, hampers cancer cell proliferation.Formule :C25H24N4O3Degré de pureté :98.75% - 99.84%Couleur et forme :Yellow SolidMasse moléculaire :428.48Ref: TM-T15429
2mg73,00€5mg110,00€1mL*10mM (DMSO)120,00€10mg178,00€25mg339,00€50mg527,00€100mg875,00€200mg1.161,00€BI 99179
CAS :BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.Formule :C23H25N3O3Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :391.46FASN Protein, Mouse, Recombinant (His)
FASN Protein, Mouse, Recombinant (His) is expressed in E.Degré de pureté :≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Couleur et forme :White Lyophilized PowderMasse moléculaire :34.23 kDa (predicted)FT113
CAS :FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFormule :C22H20FN3O4Degré de pureté :97.05%Couleur et forme :SolidMasse moléculaire :409.41PF 429242
CAS :PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).Formule :C25H35N3O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :409.56Fatostatin hydrobromide
CAS :Fatostatin hydrobromide (Fatostatin A HBr), an inhibitor of sterol regulatory element binding protein (SREBP), impairs the activation of SREBP-1 and SREBP-2.Formule :C18H18N2S·HBrDegré de pureté :98.62% - 99.91%Couleur et forme :SolidMasse moléculaire :375.33Ref: TM-T6832
5mg48,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg112,00€50mg182,00€100mg309,00€200mg447,00€500mg747,00€
