Lipoxygénase
Les lipoxygénases sont une famille d'enzymes qui catalysent l'oxygénation des acides gras polyinsaturés, conduisant à la production de médiateurs lipidiques bioactifs tels que les leucotriènes et les lipoxines. Ces médiateurs jouent un rôle crucial dans l'inflammation, les réponses immunitaires et le cancer. Les inhibiteurs de la lipoxygénase sont utilisés pour étudier leur rôle dans les maladies inflammatoires, l'asthme et le cancer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la lipoxygénase pour soutenir vos recherches en inflammation, oncologie et métabolisme lipidique.
133 produits trouvés pour "Lipoxygénase"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Zileuton
CAS :Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formule :C11H12N2O2SDegré de pureté :98.72% - 99.43%Couleur et forme :Crystalline SolidMasse moléculaire :236.29Myxochelin A
CAS :Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formule :C20H24N2O7Couleur et forme :SolidMasse moléculaire :404.419mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formule :C20H22N4O6SMasse moléculaire :446.12601(±)15-HEDE
CAS :(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formule :C20H36O3Couleur et forme :SolidMasse moléculaire :324.505Caffeoylcalleryanin
CAS :Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formule :C22H24O11Couleur et forme :SolidMasse moléculaire :464.4Lagunamycin
CAS :Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formule :C19H21N3O4Couleur et forme :SolidMasse moléculaire :355.3913-epi-12-oxo Phytodienoic Acid
CAS :13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formule :C18H28O3Couleur et forme :SolidMasse moléculaire :292.415-Lipoxygenase-IN-3
CAS :Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formule :C19H16ClN5OCouleur et forme :SolidMasse moléculaire :365.82Damnacanthol
Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267CMI977
CAS :CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formule :C16H19FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.3315-LOX-1 inhibitor 1
CAS :9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formule :C22H21ClN2O4Couleur et forme :SolidMasse moléculaire :412.87(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Formule :C20H26O4Couleur et forme :SolidMasse moléculaire :330.424DKI5
CAS :DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formule :C8H10N4SDegré de pureté :97.08%Couleur et forme :SoildMasse moléculaire :194.26ZD-2138
CAS :ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formule :C23H24FNO4Degré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :397.44CBS-1114 HCl
CAS :CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formule :C13H14ClN3Degré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :247.72ThioLox
CAS :ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.
Formule :C15H18N2OSDegré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :274.38h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formule :C22H30Cl2N6O3Couleur et forme :SolidMasse moléculaire :497.42KKII5
CAS :KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormule :C16H14N2SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :266.36Ref: TM-T77288
2mg37,00€5mg56,00€10mg84,00€25mg126,00€50mg197,00€100mg330,00€200mg472,00€1mL*10mM (DMSO)58,00€1-Naphthyl 3,5-dinitrobenzoate
CAS :1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formule :C17H10N2O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :338.27Ref: TM-T21838
5mg54,00€10mg86,00€25mg161,00€50mg245,00€100mg346,00€200mg474,00€1mL*10mM (DMSO)55,00€LOX-IN-5
CAS :LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formule :C21H25FN4O2SCouleur et forme :SolidMasse moléculaire :416.515-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in researchFormule :C19H18BrN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.335-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formule :C22H18N6O4Couleur et forme :SolidMasse moléculaire :430.42Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formule :C13H16FeN2O2Couleur et forme :SolidMasse moléculaire :288.12BLX3887
CAS :BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formule :C10H5Cl3FN3OCouleur et forme :SolidMasse moléculaire :308.522-Methyl-1-naphthol
CAS :2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.Formule :C11H10ODegré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :158.2E 6080 HCl
CAS :E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formule :C17H20ClN3O3S2Degré de pureté :99.80%Couleur et forme :SoildMasse moléculaire :413.94Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formule :C13H16N2O2RuCouleur et forme :SolidMasse moléculaire :333.35CJ-13,610 hydrochloride
CAS :CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiologicalFormule :C22H24ClN3O2SDegré de pureté :98.5%Couleur et forme :SoildMasse moléculaire :429.96Ref: TM-T27026L
1mg52,00€5mg92,00€10mg158,00€25mg335,00€50mg500,00€100mg705,00€500mg1.485,00€1mL*10mM (DMSO)148,00€Lipoxygenase
CAS :Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Couleur et forme :SolidEnazadrem phosphate
CAS :Enazadrem phosphate is a bio-active chemical. Detailed information has not been published.Formule :C18H28N3O5PCouleur et forme :SolidMasse moléculaire :397.413-Chloroiminodibenzyl
CAS :Compound PDK0184, with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0184 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C14H12ClNMasse moléculaire :229.78(S)-HEPE
CAS :8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.457Aureusidin
CAS :Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.Formule :C15H10O6Degré de pureté :98.95% - 99.18%Couleur et forme :SolidMasse moléculaire :286.24Ref: TM-TN5634
1mg197,00€5mg400,00€10mg590,00€25mg888,00€50mg1.243,00€100mg1.693,00€1mL*10mM (DMSO)384,00€Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS :Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFormule :C19H15NO4Couleur et forme :SolidMasse moléculaire :321.33Zileuton sodium
CAS :Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.
Formule :C11H11N2NaO2SCouleur et forme :SolidMasse moléculaire :258.27ML355
CAS :ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
Formule :C21H19N3O4S2Degré de pureté :98.02% - 98.2%Couleur et forme :SolidMasse moléculaire :441.52Malotilate
CAS :Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Formule :C12H16O4S2Degré de pureté :99.79% - 99.79%Couleur et forme :SolidMasse moléculaire :288.384-MMPB
CAS :15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formule :C16H19N5SDegré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :313.42Ref: TM-T8794
2mg34,00€5mg52,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€1mL*10mM (DMSO)58,00€Xanthatin
CAS :Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formule :C15H18O3Degré de pureté :98.48% - 99.96%Couleur et forme :SolidMasse moléculaire :246.3LOX-IN-3 dihydrochloride
CAS :LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Formule :C13H15Cl2FN2O2SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :353.24Ref: TM-T39986
1mg57,00€5mg120,00€10mg188,00€25mg354,00€50mg588,00€100mg938,00€200mg1.320,00€1mL*10mM (DMSO)127,00€Phenethyl ferulate
CAS :Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formule :C18H18O4Degré de pureté :99.88% - 99.91%Couleur et forme :SolidMasse moléculaire :298.33Ref: TM-TN2330
1mg56,00€5mg119,00€10mg192,00€25mg323,00€50mg475,00€100mg687,00€1mL*10mM (DMSO)114,00€Phenidone
CAS :Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formule :C9H10N2ODegré de pureté :97.24%Couleur et forme :White Solid Solid CrystallineMasse moléculaire :162.19Chebulagic acid
CAS :Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formule :C41H30O27Degré de pureté :97.82% - 99.8%Couleur et forme :SolidMasse moléculaire :954.66Ref: TM-TQ0180
1mg74,00€5mg157,00€10mg225,00€25mg376,00€50mg560,00€100mg798,00€1mL*10mM (DMSO)244,00€Licofelone
CAS :Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formule :C23H22ClNO2Degré de pureté :99.25%Couleur et forme :Yellowish SolidMasse moléculaire :379.88Ref: TM-T6568
5mg44,00€10mg66,00€25mg119,00€50mg177,00€100mg264,00€200mg394,00€500mg623,00€1mL*10mM (DMSO)48,00€S-(+)-Marmesin
CAS :S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formule :C14H14O4Degré de pureté :98.00% - ≥98%Couleur et forme :SolidMasse moléculaire :246.26PGS-IN-1
CAS :PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formule :C19H26O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :302.41Ref: TM-T10098
1mg49,00€5mg92,00€10mg167,00€25mg349,00€50mg512,00€100mg730,00€200mg982,00€1mL*10mM (DMSO)104,00€Psoralidin
CAS :Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formule :C20H16O5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :336.34Ref: TM-T3399
2mg34,00€5mg50,00€10mg81,00€25mg152,00€50mg230,00€100mg340,00€200mg497,00€1mL*10mM (DMSO)55,00€SKF-86002
CAS :SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formule :C16H12FN3SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :297.35Indirubin-3'-monoxime
CAS :Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formule :C16H11N3O2Degré de pureté :99.55%Couleur et forme :Dark Red SolidMasse moléculaire :277.283-O-Acetyl-11-hydroxy-β-boswellic acid
CAS :3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formule :C32H50O5Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :514.74Nordihydroguaiaretic acid
CAS :Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formule :C18H22O4Degré de pureté :97.82% - 99.91%Couleur et forme :SolidMasse moléculaire :302.36β-Boswellic acid
CAS :β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFormule :C30H48O3Degré de pureté :99.2% - 99.91%Couleur et forme :Off-White SolidMasse moléculaire :456.70Ref: TM-TN1097
1mg58,00€5mg137,00€10mg212,00€25mg363,00€50mg527,00€100mg747,00€1mL*10mM (DMSO)161,00€ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS :ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Formule :C12H13NO3Degré de pureté :98.9%Couleur et forme :Off-White To Light Tan Crystalline PowderMasse moléculaire :219.24BI-0115
CAS :BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formule :C15H14ClN3ODegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :287.74Pectolinarigenin
CAS :Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.
Formule :C17H14O6Degré de pureté :98.67% - 99.88%Couleur et forme :SolidMasse moléculaire :314.29Caffeic Acid
CAS :Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!Formule :C9H8O4Degré de pureté :98.89% - 99.3%Couleur et forme :Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Masse moléculaire :180.164',5-Dihydroxyflavone
CAS :4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Formule :C15H10O4Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :254.242,5-Di-tert-butylhydroquinone
CAS :2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formule :C14H22O2Degré de pureté :97.11%Couleur et forme :PelletslargecrystalsMasse moléculaire :222.32Tepoxalin
CAS :Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formule :C20H20ClN3O3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :385.84Ref: TM-T7724
1mg52,00€5mg113,00€10mg166,00€25mg371,00€50mg557,00€100mg792,00€200mg1.071,00€1mL*10mM (DMSO)126,00€5-O-Demethylnobiletin
CAS :5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.
Formule :C20H20O8Degré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :388.37FPL 62064
CAS :FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormule :C16H15N3ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :265.31Ref: TM-T8356
2mg35,00€5mg52,00€10mg86,00€25mg136,00€50mg198,00€100mg298,00€200mg414,00€1mL*10mM (DMSO)73,00€ML351
CAS :ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Formule :C15H11N3ODegré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :249.27Ref: TM-T21902
1mg50,00€5mg105,00€10mg167,00€25mg334,00€50mg505,00€100mg713,00€1mL*10mM (DMSO)117,00€Linoleyl alcohol
CAS :Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Formule :C18H34ODegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :266.463-Hydroxycoumarin
CAS :3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormule :C9H6O3Degré de pureté :99.5% - 99.77%Couleur et forme :SolidMasse moléculaire :162.1411-Keto-β-boswellic acid
CAS :11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formule :C30H46O4Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :470.68Ref: TM-TN1182
1mg57,00€5mg130,00€10mg200,00€25mg338,00€50mg497,00€100mg710,00€1mL*10mM (DMSO)133,00€Terameprocol
CAS :Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formule :C22H30O4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :358.47Wedelolactone
CAS :Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formule :C16H10O7Degré de pureté :98.07% - 99.87%Couleur et forme :SolidMasse moléculaire :314.25Ref: TM-T3384
1mg34,00€5mg71,00€10mg109,00€25mg175,00€50mg314,00€100mg414,00€500mg954,00€1mL*10mM (DMSO)50,00€CAY10698
CAS :CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formule :C17H17N3O4S2Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :391.46Ref: TM-T8950
2mg38,00€5mg52,00€10mg88,00€25mg161,00€50mg243,00€100mg355,00€200mg502,00€1mL*10mM (DMSO)62,00€U-73122
CAS :U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formule :C29H40N2O3Degré de pureté :97.50%Couleur et forme :Solid Off-WhiteMasse moléculaire :464.64a-Boswellic Acid
CAS :Produit contrôléApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Formule :C30H48O3Couleur et forme :NeatMasse moléculaire :456.74-(2-Methylpropyl)benzenemethanol
CAS :Produit contrôléFormule :C11H16OCouleur et forme :NeatMasse moléculaire :164.24MLS000536924
CAS :MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formule :C16H15N3SCouleur et forme :SolidMasse moléculaire :281.38tHGA
CAS :tHGA is a potent inhibitor of lipoxygenase.Formule :C18H24O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.38L 652343
CAS :L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formule :C22H14F3NO2S2Couleur et forme :SolidMasse moléculaire :445.48AHR-5333
CAS :AHR-5333 an antiallergy agent.Formule :C30H33F2NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.58PF-4191834
CAS :PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formule :C22H23N3O2SDegré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :393.5Ref: TM-T16503
5mg52,00€10mg84,00€25mg155,00€50mg259,00€100mg375,00€500mg815,00€1mL*10mM (DMSO)58,00€Texasin
CAS :Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Formule :C16H12O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.26L-651392
CAS :L-651392 is an inhibitor of leukotriene.Formule :C14H10BrNO3SCouleur et forme :SolidMasse moléculaire :352.2SB 210661
CAS :SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formule :C16H14F2N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.29Enazadrem
CAS :Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
Formule :C18H25N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.41Nafazatrom
CAS :Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formule :C16H16N2O2Couleur et forme :SolidMasse moléculaire :268.31LY 221068
CAS :LY 221068 is a potent antioxidant with anti-inflammatory activity.Formule :C20H30N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.5315(S)-HETrE
CAS :15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formule :C20H34O3Couleur et forme :SolidMasse moléculaire :322.48AHR-5333 mandelate
CAS :AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formule :C38H41F2NO7Couleur et forme :SolidMasse moléculaire :661.7413(S)-HpOTrE(γ)
CAS :13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formule :C18H30O4Couleur et forme :SolidMasse moléculaire :310.43Leukotriene A3 methyl ester
CAS :LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.Formule :C21H34O3Couleur et forme :SolidMasse moléculaire :334.49Setileuton tosylate
CAS :Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formule :C29H25F4N3O7SCouleur et forme :SolidMasse moléculaire :635.58Atreleuton
CAS :Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formule :C16H15FN2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.37YS-121
CAS :YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formule :C20H26ClN3O2SCouleur et forme :SolidMasse moléculaire :407.96LP117
CAS :LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).Formule :C21H23ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.95Fenleuton
CAS :Fenleuton is a 5-lipoxygenase inhibitor.Formule :C17H15FN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.31L 656224
CAS :L 656224 is a 5-LO inhibitor.Formule :C20H21ClO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.83RG 6866
CAS :RG 6866 is a inhibitor of 5-lipoxygenase.Formule :C16H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :271.31ICI 211965
CAS :ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formule :C24H23NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.51EP6
CAS :EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.Formule :C24H30N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.52HZ52
CAS :HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.Formule :C24H26ClN3O2SCouleur et forme :SolidMasse moléculaire :456Cgp 8065
CAS :Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formule :C16H15N3O4S2Couleur et forme :SolidMasse moléculaire :377.44Fluindione
CAS :Fluindione is a hematologic drug.Formule :C15H9FO2Couleur et forme :SolidMasse moléculaire :240.23Lipoxygenin
CAS :Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formule :C24H22N2O4Couleur et forme :SolidMasse moléculaire :402.44BI-L 357
CAS :BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formule :C18H18O4SCouleur et forme :SolidMasse moléculaire :330.4
