Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(3.421 produits)
- Antibiotique(945 produits)
- Antifection(27 produits)
- DHFR(30 produits)
- Synthèse ADN/ARN(808 produits)
- VHB(186 produits)
- Protéase du VIH(507 produits)
- HSV(99 produits)
- Intégrase(2 produits)
- Ribosome(6 produits)
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6441 produits trouvés pour "Microbiologie/Virologie"
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Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37GSK_WRN4
CAS :GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer researchFormule :C16H20N2O4SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :336.41PLpro-IN-6
CAS :PLpro-IN-6 (compound 6) serves as an inhibitor for the papain-like protease (PLpro), demonstrating potent activity with an IC 50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme.Formule :C29H30N6OCouleur et forme :SolidMasse moléculaire :478.59Antibacterial agent 112
Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.Formule :C35H23N5O5Couleur et forme :SolidMasse moléculaire :593.59GC373
CAS :GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.Formule :C21H29N3O5Couleur et forme :SolidMasse moléculaire :403.47Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39BRD-K98645985
CAS :BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Formule :C33H43N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.73Encephalitic alphavirus-IN-1
Alphavirus-IN-1 blocks VEEV (EC50: 0.24 μM) & EEEV (EC50: 0.16 μM), non-toxic, stable in mice plasma.Formule :C27H25FN6O2Couleur et forme :SolidMasse moléculaire :484.52RdRP-IN-5
CAS :RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].Formule :C23H21N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.43LN002
CAS :LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formule :C22H15N7Couleur et forme :SolidMasse moléculaire :377.40RAD51-IN-6
CAS :RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)Formule :C27H40N3O5PSCouleur et forme :SolidMasse moléculaire :549.66BAY-364
CAS :BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+Formule :C23H19N3O4Couleur et forme :SolidMasse moléculaire :401.41MIV-150
CAS :MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formule :C19H17FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.36LolCDE-IN-2
CAS :LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40NNRT-IN-2
CAS :NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].Formule :C19H14F3N5O3Masse moléculaire :417.34Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28LasR-IN-3
LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.Formule :C22H19N3O2Couleur et forme :SolidMasse moléculaire :357.41SP inhibitor 1
SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.Formule :C36H38N2O2Couleur et forme :SolidMasse moléculaire :530.7UNI418
CAS :UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).Formule :C22H16N6Couleur et forme :SolidMasse moléculaire :364.40Teslexivir hydrochloride
CAS :Teslexivir (BTA074) HCl inhibits HPV 6/11 by blocking E1-E2 protein interaction, vital for DNA replication. Used in condyloma research.Formule :C35H37BrClN3O4Couleur et forme :SolidMasse moléculaire :679.04Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.Formule :C18H27N3O2S3Couleur et forme :SolidMasse moléculaire :413.62PLpro-IN-5
CAS :PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.Formule :C26H33N3OCouleur et forme :SolidMasse moléculaire :403.56GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.Formule :C13H20F3N5O8SCouleur et forme :SolidMasse moléculaire :463.39Trypanothione synthetase-IN-4
Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).Formule :C29H52INO2Couleur et forme :SolidMasse moléculaire :573.63GC-78-HCl
CAS :GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.Formule :C25H25Cl3N4O4Masse moléculaire :551.85(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS :(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.Formule :C26H36F3NO4SCouleur et forme :SolidMasse moléculaire :515.629CB 30900
CAS :CB30900 is a novel and effective thymidylate synthase inhibitor.Formule :C31H32FN5O9Couleur et forme :SolidMasse moléculaire :637.61844-TFM
844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48Werner syndrome RecQ helicase-IN-2
CAS :Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.Formule :C32H34F3N9O5Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :681.67PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Formule :C18H20ClN3OSCouleur et forme :SolidMasse moléculaire :361.89JPL
CAS :JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Formule :C19H20Cl2O2Couleur et forme :SolidMasse moléculaire :351.27InhA-IN-7
CAS :InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].Formule :C17H18Cl2O2Couleur et forme :SolidMasse moléculaire :325.23BPR3P0128
CAS :BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].Formule :C22H18BrN3O2Couleur et forme :SolidMasse moléculaire :436.30NIP-22c
CAS :NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.Formule :C32H39N5O6Couleur et forme :SolidMasse moléculaire :589.68Mycobacterium Tuberculosis-IN-6
CAS :Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.Formule :C19H20FNOCouleur et forme :SolidMasse moléculaire :297.367Eprociclovir Na
CAS :Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.Formule :C11H14N5NaO3Couleur et forme :SolidMasse moléculaire :287.25SARS-CoV-2-IN-106
CAS :SARS-CoV-2-IN-106 (compound 19) is a SARS-CoV-2 papain-like protease inhibitor, displaying IC50 values of 0.44 μM for papain-like proteases and 0.18 μM for viral replication.Formule :C31H38FN5O2Couleur et forme :SolidMasse moléculaire :531.662,5-Di-tert-butyl-1,4-benzoquinone
CAS :2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55Cefamandole lithium
CAS :Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Formule :C18H17LiN6O5S2Couleur et forme :SolidMasse moléculaire :468.44Cilastatin ammonium salt
CAS :Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formule :C16H29N3O5SCouleur et forme :SolidMasse moléculaire :375.485-Iminodaunorubicin hydrochloride
CAS :5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.Formule :C27H31ClN2O9Couleur et forme :SolidMasse moléculaire :563.00Deoxythymidine-5'-triphosphate-d15
CAS :Deoxythymidine-5'-triphosphate-d15 (dTTP-d15) dilithium is a deuterium-labeled form of deoxythymidine-5'-triphosphate. Deoxythymidine-5'-triphosphate (dTTP) is a triphosphate nucleotide utilized in DNA synthesis.Formule :C10H15Li2N2O14P3Couleur et forme :SolidMasse moléculaire :509.13AN-12-H5
CAS :AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Formule :C24H23N3O4S3Couleur et forme :SolidMasse moléculaire :513.65G092
G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.Formule :C23H20Cl2N2O3Couleur et forme :SolidMasse moléculaire :443.32MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Formule :C16H23N3O9Couleur et forme :SolidMasse moléculaire :401.37Aquayamycin
CAS :Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Formule :C25H26O10Couleur et forme :SolidMasse moléculaire :486.47WQ3810
CAS :WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.Formule :C22H22F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.44Adafosbuvir
CAS :Adafosbuvir has antiviral activity.Formule :C22H29FN3O10PCouleur et forme :SolidMasse moléculaire :545.457ZHSI-1
CAS :ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that blocks EV71/CVA16 replication and virus-induced pyroptosis linked to viral pathogenesis. It effectively prevents EV71 infection in neonatal and young mice in animal models and can be used to study viral infections such as hand, foot, and mouth disease (HFMD) [1].Formule :C17H19N5Couleur et forme :SolidMasse moléculaire :293.37Cap-dependent endonuclease-IN-6
CAS :Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Formule :C23H21N3O3SCouleur et forme :SolidMasse moléculaire :419.5Antifungal agent 100
CAS :Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].Formule :C23H21N3O4SCouleur et forme :SolidMasse moléculaire :435.5Clavicoronic acid
CAS :Clavicoronic acid, a β-lactamase inhibitor, boosts penicillin antibiotics against resistant bacteria.Formule :C15H18O4Couleur et forme :SolidMasse moléculaire :262.3HIV-1-IN-86
CAS :HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formule :C20H17N3O7SCouleur et forme :SolidMasse moléculaire :443.43MA220607
CAS :MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].Formule :C34H38INCouleur et forme :SolidMasse moléculaire :587.58CTSL/CAPN1-IN-2
CAS :CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].Formule :C34H40N4O6Couleur et forme :SolidMasse moléculaire :600.77-APRA
CAS :7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formule :C10H12N2O3SMasse moléculaire :240.28RAD51-IN-5
CAS :RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)Formule :C26H38N4O5S2Couleur et forme :SolidMasse moléculaire :550.73Diclosulam
CAS :Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.Formule :C13H10Cl2FN5O3SCouleur et forme :SolidMasse moléculaire :406.22Anti-MRSA agent 23
CAS :Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.Formule :C20H17N5O3SCouleur et forme :SolidMasse moléculaire :407.446ACSS2-IN-1
CAS :ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.Formule :C27H25ClN6O2Couleur et forme :SolidMasse moléculaire :500.98ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Formule :C9H13N3Na3O12P3Couleur et forme :SolidMasse moléculaire :517.1Ibafloxacine
CAS :Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect againstFormule :C15H14FNO3Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :275.27MB076
CAS :MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formule :C9H12BN7O5S2Couleur et forme :SolidMasse moléculaire :373.18T-2513 hydrochloride
CAS :T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.Formule :C25H28ClN3O5Couleur et forme :SolidMasse moléculaire :485.96HIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).Formule :C23H26N2O4SCouleur et forme :SolidMasse moléculaire :426.53Griseofulvic Acid
CAS :Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.Formule :C16H15ClO6Masse moléculaire :338.74Alpibectir
CAS :Alpibectir has antibacterial activity [1].Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24SPR7
SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).Formule :C30H32ClN3O3Couleur et forme :SolidMasse moléculaire :518.05Homer
CAS :Homer is a probe designed to target WD repeat domain 5 (WDR5). In MV4-11 cells, Homer induces the degradation of WDR5 with a half-maximal degradation concentration (DC50) of 53 nM. At a concentration of 1 µM, Homer decreases the protein levels of WDR5 in MV4-11 cells without affecting the mRNA levels that encode WDR5.Formule :C52H60F3N9O7SCouleur et forme :SolidMasse moléculaire :1012.15H2S scavenger 1 (triflate)
H2S scavenger 1 triflate (Compound 7b) serves as a selective H2S depleting agent, particularly against glutathione. This compound impedes the formation of bacterial biofilms and enhances the sensitivity of Staphylococcus aureus to gentamicin or photosensitizers by depleting H2S.Formule :C13H16F3N5O6SMasse moléculaire :427.36BRD-4592
CAS :BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.Formule :C17H15FN2OCouleur et forme :SolidMasse moléculaire :282.312RCB18350
CAS :RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.Formule :C19H18F3N3O4SCouleur et forme :SolidMasse moléculaire :441.424Kinamycin B
CAS :Kinamycin B is an antibacterial agent with anticancer activity.Formule :C20H16N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.35Chitinase-IN-4
Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.Formule :C21H24ClN7Couleur et forme :SolidMasse moléculaire :409.92Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Formule :C16H23N3S2Couleur et forme :SolidMasse moléculaire :321.5A 76889
CAS :A 76889 is an inhibitor of HIV-1 protease.Formule :C44H58N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :794.988-Hydroxyerythromycin A
CAS :8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.Formule :C37H67NO14Couleur et forme :SolidMasse moléculaire :749.926BMT-052
CAS :BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formule :C30H17D9F4N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :635.61Methyl piperazine-2-carboxylate
CAS :Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.Formule :C6H12N2O2Couleur et forme :SolidMasse moléculaire :144.172CYP51-IN-14
CAS :CYP51-IN-14 (compound 1n), a derivative of Fluconazole, functions as an effective antifungal agent. This compound inhibits Microsporum gypseum and Candida albicans with a minimum inhibitory concentration (MIC80) of 1 μg/mL.Formule :C21H20Cl2F2N4OMasse moléculaire :453.31HBV-IN-11
CAS :HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).Formule :C21H24ClNO6Couleur et forme :SolidMasse moléculaire :421.87KL-50
CAS :KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.Formule :C7H7FN6O2Couleur et forme :SolidMasse moléculaire :226.17BAR-072
CAS :BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.Formule :C18H13N3O6Couleur et forme :SolidMasse moléculaire :367.3128-Deazafolic acid
CAS :8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFormule :C23H23N3O5Couleur et forme :SolidMasse moléculaire :421.45SARS-CoV-2 Mpro-IN-31
CAS :SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.Formule :C31H34Cl2N4O7Couleur et forme :SolidMasse moléculaire :645.53Polθ-IN-5
CAS :Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.Formule :C23H18ClF2N7O3SCouleur et forme :SolidMasse moléculaire :545.95NNRT-IN-5
CAS :NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.Formule :C27H22N8Couleur et forme :SolidMasse moléculaire :458.52Antitumor agent-74
Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.Formule :C26H23FN6Couleur et forme :SolidMasse moléculaire :438.5CYP51-IN-7
CAS :CYP51-IN-7 (compound 1g) is an analogue of Fluconazole and serves as an effective antifungal agent. It exhibits inhibitory activity against Microsporum gypseum and Candida albicans, with MIC80 values of 62.5 ng/mL and 250 ng/mL, respectively.Formule :C21H21ClF2N4OMasse moléculaire :418.87AYK004-C1
CAS :AYK004-C1 is a TLR agonist used in the formulation of immunological adjuvants.Formule :C35H58F3N7O3Masse moléculaire :681.88Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formule :C22H28N6OCouleur et forme :SolidMasse moléculaire :392.512(S)-HETE
CAS :Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.
Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Formule :C9H20N2O8Couleur et forme :SolidMasse moléculaire :284.26bc1 Complex-IN-1
CAS :Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).Formule :C16H22N6O5S2Couleur et forme :SolidMasse moléculaire :442.513ZG297
CAS :ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.Formule :C31H35F3N4O3Couleur et forme :SolidMasse moléculaire :568.63DXR-IN-3
CAS :DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.Formule :C10H12Cl2NO5PSCouleur et forme :SolidMasse moléculaire :360.15Kalafungin
CAS :Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Formule :C16H12O6Couleur et forme :SolidMasse moléculaire :300.26
