Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(3.423 produits)
- Antibiotique(945 produits)
- Antifection(27 produits)
- DHFR(30 produits)
- Synthèse ADN/ARN(808 produits)
- VHB(186 produits)
- Protéase du VIH(507 produits)
- HSV(99 produits)
- Intégrase(2 produits)
- Ribosome(5 produits)
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6444 produits trouvés pour "Microbiologie/Virologie"
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SARS-CoV-2-IN-106
CAS :SARS-CoV-2-IN-106 (compound 19) is a SARS-CoV-2 papain-like protease inhibitor, displaying IC50 values of 0.44 μM for papain-like proteases and 0.18 μM for viral replication.Formule :C31H38FN5O2Couleur et forme :SolidMasse moléculaire :531.66Antimalarial agent 44
Antimalarial agent 44 (Compound 3) is an antiparasitic agent effective against malaria. It exhibits good permeability in MDCK-MDR1 cell monolayers and has a high clearance rate in mouse liver microsomes.Formule :C37H37N5O7Couleur et forme :SolidMasse moléculaire :663.72MLEB-22043
MLEB-22043 is a synthetic siderophore-monocyclic β-lactam conjugate which enters bacteria through TonB-dependent transport proteins utilizing its siderophore component, subsequently exerting antibacterial activity via its β-lactam portion. This compound acts as a broad-spectrum antibiotic, exhibiting significant inhibitory activity against pathogens such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa.Formule :C25H25N9O11S2Couleur et forme :SolidMasse moléculaire :691.652,5-Di-tert-butyl-1,4-benzoquinone
CAS :2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55Cefamandole lithium
CAS :Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Formule :C18H17LiN6O5S2Couleur et forme :SolidMasse moléculaire :468.44Cilastatin ammonium salt
CAS :Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formule :C16H29N3O5SCouleur et forme :SolidMasse moléculaire :375.48UNI418
CAS :UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).Formule :C22H16N6Couleur et forme :SolidMasse moléculaire :364.40Chitin synthase inhibitor 12
Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88SARS-CoV-2-IN-8
SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).Formule :C35H38N6O3Couleur et forme :SolidMasse moléculaire :590.71Antifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Formule :C24H26N4Se2Couleur et forme :SolidMasse moléculaire :528.41BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formule :C26H33FN2O4SCouleur et forme :SolidMasse moléculaire :488.61Aurantiogliocladin
CAS :Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.Formule :C10H12O4Couleur et forme :SolidMasse moléculaire :196.2UMPK ligand 1
CAS :UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).
Formule :C15H22N4O5SCouleur et forme :SolidMasse moléculaire :370.4245-Methylcytosine hydrochloride
CAS :5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.Formule :C5H8ClN3OCouleur et forme :SolidMasse moléculaire :161.59Streptothricin F
CAS :Streptothricin F is a biochemical.Formule :C19H34N8O8Couleur et forme :SolidMasse moléculaire :502.52Antibacterial agent 204
CAS :Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].Formule :C14H18N2Couleur et forme :SolidMasse moléculaire :214.31PLpro-IN-5
CAS :PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.Formule :C26H33N3OCouleur et forme :SolidMasse moléculaire :403.56QPX7728 bis-acetoxy methyl ester
CAS :QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formule :C15H14BFO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.085-Fluorouridine 5'-phosphate
CAS :5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.Formule :C9H12FN2O9PCouleur et forme :SolidMasse moléculaire :342.172BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formule :C25H30ClFN2OCouleur et forme :SolidMasse moléculaire :428.97HCV-IN-40
CAS :HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.Formule :C21H26BrFN3O9PCouleur et forme :SolidMasse moléculaire :594.32BAY-364
CAS :BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+Formule :C23H19N3O4Couleur et forme :SolidMasse moléculaire :401.41Clavicoronic acid
CAS :Clavicoronic acid, a β-lactamase inhibitor, boosts penicillin antibiotics against resistant bacteria.Formule :C15H18O4Couleur et forme :SolidMasse moléculaire :262.3PF 03709270
CAS :PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Formule :C19H27NO7S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.61Eprociclovir Na
CAS :Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.Formule :C11H14N5NaO3Couleur et forme :SolidMasse moléculaire :287.25(R)-CSN5i-3
CAS :(R)-CSN5i-3 is CSN5i-3 of the R configuration.Formule :C28H29F2N5O2Degré de pureté :99.76% - 99.97%Couleur et forme :SolidMasse moléculaire :505.56DXR-IN-3
CAS :DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.Formule :C10H12Cl2NO5PSCouleur et forme :SolidMasse moléculaire :360.15Fabimycin
CAS :Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Formule :C23H25ClN4O3Couleur et forme :SolidMasse moléculaire :440.92NBD-14189
CAS :NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Formule :C18H16F4N4O2SCouleur et forme :SolidMasse moléculaire :428.40Enzyme-IN-3 disodium
CAS :Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.Formule :C20H13N3Na2O8S2Couleur et forme :SolidMasse moléculaire :533.442HBV-IN-19 TFA
CAS :HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.Formule :C26H31F3N2O8Couleur et forme :SolidMasse moléculaire :556.53Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Formule :C24H25N3O5Couleur et forme :SolidMasse moléculaire :435.47Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Formule :C16H22ClNOSCouleur et forme :SolidMasse moléculaire :311.877-Hydroxytropolone
CAS :7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12MCB-3681
CAS :MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin's active substance.Formule :C31H32F2N4O8Couleur et forme :SolidMasse moléculaire :626.6ZINC000104379474
ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.Formule :C27H33N3O10Couleur et forme :SolidMasse moléculaire :559.57RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Formule :C12H10F2OCouleur et forme :SolidMasse moléculaire :208.2BRD-K98645985
CAS :BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Formule :C33H43N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.73Cephalosporin C
CAS :Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.Formule :C16H21N3O8SCouleur et forme :SolidMasse moléculaire :415.418Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Formule :C14H7Cl2F3N2OCouleur et forme :SolidMasse moléculaire :347.12ZK-316
CAS :ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Formule :C27H22D6N6O3S2Couleur et forme :SolidMasse moléculaire :554.72NBTIs-IN-5
CAS :NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48NITD-688
CAS :NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.Formule :C25H32N4O3S2Couleur et forme :SolidMasse moléculaire :500.68Cap-dependent endonuclease-IN-25
CAS :Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48Antifungal agent 127
CAS :Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.Formule :C13H12ClN3OCouleur et forme :SolidMasse moléculaire :261.707Antibacterial agent 281
CAS :Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formule :C23H24N6OCouleur et forme :SolidMasse moléculaire :400.48XR8-89
CAS :XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.Formule :C29H36N4O2SCouleur et forme :SolidMasse moléculaire :504.69Quorum sensing-IN-9
CAS :Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.Formule :C9H10OS2Couleur et forme :SolidMasse moléculaire :198.305Pibrozelesin
CAS :Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.Formule :C32H36BrN5O8Couleur et forme :SolidMasse moléculaire :698.56BMIM-TFSI
CAS :BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.Formule :C10H15F6N3O4S2Couleur et forme :SolidMasse moléculaire :419.364MsbA-IN-4
MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).Formule :C23H18Cl2FN5OCouleur et forme :SolidMasse moléculaire :470.33Secutrelvir
CAS :Secutrelvir inhibits the 3CL protease (3CL protease), thereby exhibiting antiviral activity by preventing the replication of SARS-CoV-2.Formule :C23H16Cl2F3N5O2Couleur et forme :SolidMasse moléculaire :522.307Antibacterial agent 81
CAS :Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Formule :C33H28N2O8Couleur et forme :SolidMasse moléculaire :580.58CDA-IN-1
CAS :CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.Formule :C15H14N2O6Couleur et forme :SolidMasse moléculaire :318.281MPro N3
CAS :Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.Formule :C35H48N6O8Couleur et forme :SolidMasse moléculaire :680.79SARS-CoV-2 3CLpro-IN-32
CAS :SARS-CoV-2 3CLpro-IN-32 (compound B16) is a potent inhibitor of the SARS-CoV-2 3CLpro enzyme, with an IC50 of 0.109 μM. It also demonstrates antiviral activity against the coronavirus HCoV-OC43, with an EC50 of 1.99 μM.Formule :C30H37N3O4S3Couleur et forme :SolidMasse moléculaire :599.83ZLM-66
ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.Couleur et forme :Solid4-Chloropyridine
CAS :4-Chloropyridine acts as an inhibitor of Nicotinamide N-methyltransferase (NNMT). Serving as a substrate for NNMT, this compound enhances the electrophilicity at the C4 position through methylation of the pyridine nitrogen. This modification facilitates an aromatic nucleophilic substitution reaction with the non-catalytic cysteine (C159) in NNMT, ultimately leading to suicidal activity inhibition of the enzyme. 4-Chloropyridine is a promising candidate for the development of activity-based probes targeting NNMT functions.Formule :C5H4ClNCouleur et forme :SolidMasse moléculaire :113.55HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Formule :C16H15F2N3OSCouleur et forme :SolidMasse moléculaire :335.37Emtricitabine triphosphate
CAS :Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formule :C8H13FN3O12P3SCouleur et forme :SolidMasse moléculaire :487.19FtsZ-IN-13
CAS :FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.Formule :C18H14N2O4S2Couleur et forme :SolidMasse moléculaire :386.445RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Formule :C17H17Br2N3O2Couleur et forme :SolidMasse moléculaire :455.14ACHN-975
CAS :ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formule :C20H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.41BI-2540
CAS :BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Formule :C24H15ClF5NO5Couleur et forme :SolidMasse moléculaire :527.83SARS-CoV-2 3CLpro-IN-28
CAS :SARS-CoV-2 3CLpro-IN-28 (Compound 19) is an inhibitor of SARS-CoV-2 3CLpro, exhibiting an IC50 value of 0.018 μM.Formule :C27H18Cl2N4O4Couleur et forme :SolidMasse moléculaire :533.362Faldaprevir sodium
CAS :Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Formule :C40H48BrN6NaO9SCouleur et forme :SolidMasse moléculaire :891.81Antiviral agent 7
Antiviral agent 7 is a peptide-based coating that kills viruses.Formule :C29H31F2N3O6Couleur et forme :SolidMasse moléculaire :555.57PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Formule :C17H18ClN3OSCouleur et forme :SolidMasse moléculaire :347.86HBV-IN-12
CAS :HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)Formule :C23H27NO8Couleur et forme :SolidMasse moléculaire :445.46Carumonam Sodium
CAS :Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.Formule :C12H12N6Na2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.37Bilanafos
CAS :Bilanafos is an agent of Anti-Bacterial.Formule :C11H22N3O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.283'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite
CAS :3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.Formule :C41H50N9O3PCouleur et forme :SolidMasse moléculaire :747.87Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37D-CS319
CAS :D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formule :C7H11NO2S3Couleur et forme :SolidMasse moléculaire :237.36Anti-MRSA agent 2
CAS :Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.Formule :C18H10Br2N2OCouleur et forme :SolidMasse moléculaire :430.09HBV-IN-24
HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.Formule :C23H27NO6Couleur et forme :SolidMasse moléculaire :413.46MK-8876
CAS :MK-8876 is an Inhibitor of HCV NS5B Site D.Formule :C32H24F2N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :614.62NDM-1 inhibitor-3
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.Formule :C16H12O4Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :268.26Pneumolysin-IN-1
CAS :Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].Formule :C23H16Cl2N2O4Couleur et forme :SolidMasse moléculaire :455.29MA220607
CAS :MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].Formule :C34H38INCouleur et forme :SolidMasse moléculaire :587.58MK-3402
CAS :MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .Formule :C15H19N9O5S2Couleur et forme :SolidMasse moléculaire :469.50(Z)-Lanoconazole
(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.Formule :C14H10ClN3S2Couleur et forme :SolidMasse moléculaire :319.83PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Formule :C16H27N5O3SCouleur et forme :SolidMasse moléculaire :369.48Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Formule :C26H23FN6Couleur et forme :SolidMasse moléculaire :438.5D-G23
CAS :D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.Formule :C19H22N4O3Couleur et forme :SolidMasse moléculaire :354.403PptT-IN-1
PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.Formule :C18H29N5O2Couleur et forme :SolidMasse moléculaire :347.46Triazophos
CAS :Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.Formule :C12H16N3O3PSCouleur et forme :SolidMasse moléculaire :313.31Mycobacterium Tuberculosis-IN-6
CAS :Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.Formule :C19H20FNOCouleur et forme :SolidMasse moléculaire :297.367MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.Formule :C16H16N4O5Couleur et forme :SolidMasse moléculaire :344.32Valopicitabine dihydrochloride
CAS :Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formule :C15H25ClN4O6Couleur et forme :SolidMasse moléculaire :392.84AN-12-H5
CAS :AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Formule :C24H23N3O4S3Couleur et forme :SolidMasse moléculaire :513.652-CEES
CAS :2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.Formule :C4H9ClSCouleur et forme :SolidMasse moléculaire :124.632Piperacillin hydrate
CAS :Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.Formule :C23H29N5O8SCouleur et forme :SolidMasse moléculaire :535.57G092
G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.Formule :C23H20Cl2N2O3Couleur et forme :SolidMasse moléculaire :443.32MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Formule :C16H23N3O9Couleur et forme :SolidMasse moléculaire :401.37BRN3OMe
CAS :BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.Formule :C7H13N3O4Couleur et forme :SolidMasse moléculaire :203.196Zorubicin
CAS :Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.Formule :C34H35N3O10Couleur et forme :SolidMasse moléculaire :645.66Antifungal agent 13
CAS :Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Formule :C22H29N5O2Couleur et forme :SolidMasse moléculaire :395.5
