Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.949 produits)
- Antibiotique(918 produits)
- Antifection(23 produits)
- DHFR(32 produits)
- Synthèse ADN/ARN(706 produits)
- VHB(176 produits)
- Protéase du VIH(447 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5832 produits trouvés pour "Microbiologie/Virologie"
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BAY-364
CAS :<p>BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+</p>Formule :C23H19N3O4Couleur et forme :SolidMasse moléculaire :401.41Valopicitabine dihydrochloride
CAS :<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formule :C15H25ClN4O6Couleur et forme :SolidMasse moléculaire :392.84HBV-IN-48
CAS :<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Formule :C22H15F4N3O3Couleur et forme :SolidMasse moléculaire :445.37Ladirubicin
CAS :<p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>Formule :C29H31NO11SCouleur et forme :SolidMasse moléculaire :601.62Lamivudine, (+/-)-trans-
CAS :<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Formule :C8H11N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :229.26NDM-1 inhibitor-5
CAS :<p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>Formule :C24H23NO4Couleur et forme :SolidMasse moléculaire :389.44GSK_WRN4
CAS :<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formule :C16H20N2O4SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :336.41CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Formule :C26H26N2O6SCouleur et forme :SolidMasse moléculaire :494.56HSV-TK substrate
CAS :<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Formule :C11H15N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.27OUN58101
CAS :<p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>Formule :C32H36N6O6Couleur et forme :SolidMasse moléculaire :600.66Adafosbuvir
CAS :<p>Adafosbuvir has antiviral activity.</p>Formule :C22H29FN3O10PCouleur et forme :SolidMasse moléculaire :545.457Beclabuvir
CAS :<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Formule :C36H45N5O5SDegré de pureté :99.87% - 99.93%Couleur et forme :SolidMasse moléculaire :659.84MraY-IN-2
<p>MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.</p>Formule :C16H23N3O9Couleur et forme :SolidMasse moléculaire :401.37CDA-IN-4
CAS :<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Formule :C10H9BrN4O2SCouleur et forme :SolidMasse moléculaire :329.17PLpro-IN-5
CAS :<p>PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formule :C26H33N3OCouleur et forme :SolidMasse moléculaire :403.562'-(2-Nitrobenzyl)-ATP
CAS :<p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>Formule :C17H21N6O15P3Couleur et forme :SolidMasse moléculaire :642.30Antibacterial agent 204
CAS :<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Formule :C14H18N2Couleur et forme :SolidMasse moléculaire :214.31HKI12134085
CAS :<p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>Formule :C18H18F3N3O5SCouleur et forme :SolidMasse moléculaire :445.41Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44G092
<p>G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.</p>Formule :C23H20Cl2N2O3Couleur et forme :SolidMasse moléculaire :443.32KWR095
CAS :<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105PqsR-IN-1
<p>PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.</p>Formule :C17H18ClN3OSCouleur et forme :SolidMasse moléculaire :347.86Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Formule :C21H24ClN7Couleur et forme :SolidMasse moléculaire :409.928-Hydroxyerythromycin A
CAS :<p>8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.</p>Formule :C37H67NO14Couleur et forme :SolidMasse moléculaire :749.926Aurachin C
CAS :<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.535Pneumolysin-IN-1
CAS :<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Formule :C23H16Cl2N2O4Couleur et forme :SolidMasse moléculaire :455.29Neocryptolepine-Cl
CAS :<p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>Formule :C16H11ClN2Couleur et forme :SolidMasse moléculaire :266.725MPro N3
CAS :<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Formule :C35H48N6O8Couleur et forme :SolidMasse moléculaire :680.79BioA-IN-1
CAS :<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Formule :C18H17NO3SCouleur et forme :SolidMasse moléculaire :327.397Altersolanol A
CAS :<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Formule :C16H16O8Couleur et forme :SolidMasse moléculaire :336.29Antibacterial agent 188
CAS :<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3Antifungal agent 100
CAS :<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formule :C23H21N3O4SCouleur et forme :SolidMasse moléculaire :435.5Neuraminidase-IN-18
CAS :<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Formule :C22H18FN3O3SCouleur et forme :SolidMasse moléculaire :423.46Finafloxacin
CAS :<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formule :C20H19FN4O4Couleur et forme :SolidMasse moléculaire :398.39Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55Quorum sensing-IN-9
CAS :<p>Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.</p>Formule :C9H10OS2Couleur et forme :SolidMasse moléculaire :198.305Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39N-Cbz-L-Cysteine
CAS :<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Formule :C11H13NO4SCouleur et forme :SolidMasse moléculaire :255.29G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formule :C24H19Cl2FO3Couleur et forme :SolidMasse moléculaire :445.31Antimicrobial agent-29
CAS :<p>Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].</p>Formule :C19H14N4O4SCouleur et forme :SolidMasse moléculaire :394.4Arterolane
CAS :<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Formule :C22H36N2O4Couleur et forme :SolidMasse moléculaire :392.53And1 degrader 1
CAS :<p>And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.</p>Formule :C26H27Cl2N3OCouleur et forme :SolidMasse moléculaire :468.42NIP-22c
CAS :<p>NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.</p>Formule :C32H39N5O6Couleur et forme :SolidMasse moléculaire :589.68KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Formule :C12H10BN3O2SCouleur et forme :SolidMasse moléculaire :271.1SARS-CoV-2-IN-99
CAS :<p>SARS-CoV-2-IN-99 (compound 58) is an inhibitor of the main protease of SARS-CoV-2.</p>Formule :C20H16Br2NO4PCouleur et forme :SolidMasse moléculaire :525.133-Deazaguanosine
CAS :<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formule :C11H14N4O5Couleur et forme :SolidMasse moléculaire :282.25Laninamivir trifluoroacetate
CAS :<p>Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.</p>Formule :C15H23F3N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.363Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46SHEN26
CAS :<p>SHEN26 (ATY014) is a potent, orally active RdRp inhibitor with an IC50 of 1.36 μM for SARS-CoV-2. As a 5'-cyclohexanecarboxylate derivative of GS-441524, SHEN26 inhibits viral nucleic acid synthesis, achieving antiviral effects. SHEN26 can be used for COVID-19 research [1] [2].</p>Formule :C19H23N5O5Couleur et forme :SolidMasse moléculaire :401.42GRL-190-21
CAS :<p>GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].</p>Formule :C24H34F3N5O4Couleur et forme :SolidMasse moléculaire :513.55HBV/HDV-IN-3
CAS :<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Formule :C28H27BrF3N5O3Couleur et forme :SolidMasse moléculaire :618.44MraY-IN-3
<p>MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).</p>Formule :C35H45N3O5Couleur et forme :SolidMasse moléculaire :587.75HldA/E-IN-1
CAS :<p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>Formule :C8H17FO13P2Couleur et forme :SolidMasse moléculaire :402.16Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28SARS-CoV-2-IN-82
CAS :<p>SARS-CoV-2-IN-82 (compound A) acts as an inhibitor of the Programmed-1 ribosomal frameshift (-1 PRF) in SARS-CoV-2 [1].</p>Formule :C18H18N2Couleur et forme :SolidMasse moléculaire :262.35HIV-1 inhibitor-61
CAS :<p>HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].</p>Formule :C24H24F2N2O2SCouleur et forme :SolidMasse moléculaire :442.52Antibacterial agent 68
<p>Antibacterial agent 68 targets drug-resistant E. coli at 0.007 mM with low cytotoxicity.</p>Formule :C26H25BrN4O7Couleur et forme :SolidMasse moléculaire :585.4Uridine 3',5'-diphosphate
CAS :<p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>Formule :C9H14N2O12P2Couleur et forme :SolidMasse moléculaire :404.16MBX-1162
CAS :<p>MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.</p>Formule :C30H28N6Couleur et forme :SolidMasse moléculaire :472.58A 76889
CAS :<p>A 76889 is an inhibitor of HIV-1 protease.</p>Formule :C44H58N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :794.98BI-2540
CAS :<p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>Formule :C24H15ClF5NO5Couleur et forme :SolidMasse moléculaire :527.83SLU-10906
CAS :<p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>Formule :C22H21BFN5O2Couleur et forme :SolidMasse moléculaire :417.244KL-50
CAS :<p>KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.</p>Formule :C7H7FN6O2Couleur et forme :SolidMasse moléculaire :226.17Pibrozelesin
CAS :<p>Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.</p>Formule :C32H36BrN5O8Couleur et forme :SolidMasse moléculaire :698.56BRD-4592
CAS :<p>BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.</p>Formule :C17H15FN2OCouleur et forme :SolidMasse moléculaire :282.312Metallo-β-lactamase-IN-13
CAS :<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Formule :C15H10F3N7O2S2Couleur et forme :SolidMasse moléculaire :441.41RdRP-IN-4
<p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>Formule :C17H17Br2N3O2Couleur et forme :SolidMasse moléculaire :455.14Glasmacinal
CAS :<p>Glasmacinal is a non-antibacterial macrolide compound with anti-inflammatory activities.</p>Formule :C37H62N2O10Couleur et forme :SolidMasse moléculaire :694.90Antifungal agent 13
CAS :<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83Nikkomycin Z
CAS :<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formule :C20H25N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44Antimicrobial agent-38
CAS :<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Formule :C14H11N3O4SCouleur et forme :SolidMasse moléculaire :317.32AK-968-11563024
CAS :<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Formule :C18H13I2N9O5Couleur et forme :SolidMasse moléculaire :689.162N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS :<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Formule :C17H19N5O5Couleur et forme :SolidMasse moléculaire :373.363Hyalodendrin
CAS :<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formule :C14H16N2O3S2Couleur et forme :SolidMasse moléculaire :324.42Chitin synthase inhibitor 1
<p>Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.</p>Formule :C22H20ClN3O3Couleur et forme :SolidMasse moléculaire :409.87β-Glucuronidase-IN-3
CAS :<p>β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric inhibitor targeting β-glucuronidase. It exhibits potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) with an IC50 of 12.9 nM. The compound exerts its inhibitory effect through reversible covalent modification of cysteine residues (Cys28, Cys443, and Cys197) on EcGUS. It is applicable in research on gut microbiota-related diseases, particularly in reducing the toxic side effects of Irinotecan and non-steroidal anti-inflammatory drugs (NSAIDs).</p>Formule :C10H7N3OSeCouleur et forme :SolidMasse moléculaire :264.14RECTAS-2.0
CAS :<p>RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G>A mutation, intended for research in Fabry disease.</p>Formule :C18H17ClN4O4Couleur et forme :SolidMasse moléculaire :388.805DHX9-IN-9
CAS :<p>DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].</p>Formule :C21H21ClFN5O3S2Couleur et forme :SolidMasse moléculaire :510LY 215890
CAS :<p>LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.</p>Formule :C13H12ClN5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.78Diploicin
CAS :<p>Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).</p>Formule :C16H10Cl4O5Couleur et forme :SolidMasse moléculaire :424.06Faldaprevir
CAS :<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Formule :C40H49BrN6O9SDegré de pureté :99.04% - 99.19%Couleur et forme :SolidMasse moléculaire :869.82GSK5852
<p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>Formule :C27H27BF2N2O6SCouleur et forme :SolidMasse moléculaire :556.39HIV-1 inhibitor-17
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).</p>Formule :C32H32N4O5SCouleur et forme :SolidMasse moléculaire :584.69Artefenomel
CAS :<p>Artefenomel (OZ439) is an orally active anti-malarial ozone analog with antiviral activity for the study of SARS-CoV-2 infections and malaria infections.</p>Formule :C28H39NO5Couleur et forme :SolidMasse moléculaire :469.61SARS-CoV-2-IN-80
CAS :<p>SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].</p>Formule :C16H10O2SCouleur et forme :SolidMasse moléculaire :266.31Desthiazolylmethyl ritonavir
CAS :<p>Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.</p>Formule :C33H43N5O4SCouleur et forme :SolidMasse moléculaire :605.791RAD51-IN-5
CAS :<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Formule :C26H38N4O5S2Couleur et forme :SolidMasse moléculaire :550.73HIV-1 protease-IN-6
<p>HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.</p>Formule :C27H31FN2O6SCouleur et forme :SolidMasse moléculaire :530.61HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Formule :C23H26N2O4SCouleur et forme :SolidMasse moléculaire :426.53LasR antagonist 1
CAS :<p>LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].</p>Formule :C20H15F3N2O3Couleur et forme :SolidMasse moléculaire :388.34NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formule :C14H9IN2O3SCouleur et forme :SolidMasse moléculaire :412.2Anticancer agent 36
<p>Compound 11: Sulfonylurea derivative, antimicrobial, anticancer; MIC 0.039-0.156 mg/mL; A549 IC50: 19.7 μg/mL, PC3 IC50: 11.9 μg/mL.</p>Formule :C21H17N3O3S2Couleur et forme :SolidMasse moléculaire :423.51K13787
CAS :<p>K13787 is an acetohydroxy acid synthase (AHAS) inhibitor with antibacterial properties. It exhibits antimicrobial activity against various non-tuberculous mycobacteria (NTM) as well as clarithromycin (CLR) resistant strains.</p>Formule :C14H11F2N5O4SCouleur et forme :SolidMasse moléculaire :383.33ABT-072
CAS :<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.55TBAJ-5307
CAS :<p>TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].</p>Formule :C30H35BrN4O6Couleur et forme :SolidMasse moléculaire :627.53Antibiofilm agent-4
CAS :<p>Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.</p>Formule :C15H15NO3Masse moléculaire :257.28Cap-dependent endonuclease-IN-2
<p>Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.</p>Formule :C30H24FN3O7SCouleur et forme :SolidMasse moléculaire :589.591,5-Dideoxy-1,5-imino-D-mannitol
CAS :<p>1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.</p>Formule :C6H13NO4Couleur et forme :SolidMasse moléculaire :163.172Antibacterial agent 169
CAS :<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Formule :C19H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :442.34Cetefloxacin
CAS :<p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>Formule :C20H16F3N3O3Masse moléculaire :403.35Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formule :C20H16F3N7O2S2Couleur et forme :SolidMasse moléculaire :507.51PAV-104
CAS :<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Formule :C29H35N5O6SCouleur et forme :SolidMasse moléculaire :581.68Cefclidin
CAS :<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Formule :C21H26N8O6S2Couleur et forme :SolidMasse moléculaire :550.611Antibacterial agent 113
<p>Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.</p>Formule :C29H18ClN5OCouleur et forme :SolidMasse moléculaire :487.94GC-78-HCl
CAS :<p>GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.</p>Formule :C25H25Cl3N4O4Masse moléculaire :551.85Thiolactomycin
CAS :<p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>Formule :C11H14O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :210.29Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Formule :C15H16BrN3O2Couleur et forme :SolidMasse moléculaire :350.21GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Formule :C13H20F3N5O8SCouleur et forme :SolidMasse moléculaire :463.39Pks13-TE inhibitor 4
CAS :<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Formule :C26H25N5O6Masse moléculaire :503.51Lapyrium chloride
CAS :<p>Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.</p>Formule :C21H35ClN2O3Masse moléculaire :398.97CM-728
CAS :<p>CM-728 is an oxazanonaphthoquinone that exhibits cytotoxic and antibacterial properties. It acts as a human peroxidase-1 inhibitor and serves as a source of oxidative stress affecting mitochondrial function.</p>Formule :C22H14N2O5Couleur et forme :SolidMasse moléculaire :386.357Antibacterial agent 266
CAS :<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.246Griseofulvic Acid
CAS :<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Formule :C16H15ClO6Masse moléculaire :338.747-APRA
CAS :<p>7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.</p>Formule :C10H12N2O3SMasse moléculaire :240.28SARS-CoV-2 Mpro-IN-25
CAS :<p>SARS-CoV-2 Mpro-IN-25 (Compound 3a) is a protease inhibitor for SARS-CoV-2, exhibiting an IC50 value of 0.26 μM. It demonstrates antiviral activity and is useful for research in the field of pneumonia.</p>Formule :C13H10FNO4Couleur et forme :SolidMasse moléculaire :263.22NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Formule :C24H21N3O5SCouleur et forme :SolidMasse moléculaire :463.51Antibacterial agent 87
<p>Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).</p>Formule :C31H46N2O6SCouleur et forme :SolidMasse moléculaire :574.77Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formule :C29H52INO2Couleur et forme :SolidMasse moléculaire :573.63FPI-1465
CAS :<p>FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>Formule :C11H18N4O7SCouleur et forme :SolidMasse moléculaire :350.35Cefempidone
CAS :<p>Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.</p>Formule :C22H21N7O6S2Masse moléculaire :543.58Antibacterial agent 262
CAS :<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Formule :C17H18F2N6O4S3Couleur et forme :SolidMasse moléculaire :504.554MurA-IN-6
CAS :<p>MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.</p>Formule :C22H17N3O3SCouleur et forme :SolidMasse moléculaire :403.454Chitinase-IN-5
<p>Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.</p>Formule :C20H21ClFN7Couleur et forme :SolidMasse moléculaire :413.88CTSL/CAPN1-IN-2
CAS :<p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>Formule :C34H40N4O6Couleur et forme :SolidMasse moléculaire :600.7Apalcillin
CAS :<p>Apalcillin (PC-904) combined with Ro 48-1220 (a penicillin sulfone β-lactamase inhibitor) exhibits broad-spectrum activity against Gram-negative aerobic and anaerobic bacteria, excluding Klebsiella acid-producing strains. This combination shows strong efficacy against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae with an effective MIC of 11 μg/mL. Additionally, it inhibits Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter at low MICs (0.25 to 4 μg/mL). However, it has limited efficacy against oxacillin-resistant staphylococci and some Gram-positive bacteria. Apalcillin/Ro 48-1220's effectiveness against certain extended-spectrum β-lactamase-producing Escherichia coli is comparable to piperacillin/tazobactam, though it is less effective against SHV-type β-lactamases.</p>Formule :C25H23N5O6SMasse moléculaire :521.555-Iminodaunorubicin hydrochloride
CAS :<p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>Formule :C27H31ClN2O9Couleur et forme :SolidMasse moléculaire :563.00CDK9-IN-34
CAS :<p>CDK9-IN-34 (Compound 1b) is an inhibitor of CDK9 with an IC50 of 0.25 μM. It exhibits cytotoxicity against cancer cell lines HCT116, MCF7, and K652, with IC50 values of 1.43 μM, 3.01 μM, and 50.27 μM, respectively. Additionally, CDK9-IN-34 demonstrates antiviral activity against coronavirus 229E with an IC50 of 145.92 μM.</p>Formule :C18H20N4Couleur et forme :SolidMasse moléculaire :292.38SARS-CoV-2-IN-22
CAS :<p>SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).</p>Formule :C27H24N2O3SCouleur et forme :SolidMasse moléculaire :456.56Diclosulam
CAS :<p>Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.</p>Formule :C13H10Cl2FN5O3SCouleur et forme :SolidMasse moléculaire :406.22Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Formule :C28H32BrN3O2Couleur et forme :SolidMasse moléculaire :522.48T-2513 hydrochloride
CAS :<p>T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.</p>Formule :C25H28ClN3O5Couleur et forme :SolidMasse moléculaire :485.96Anti-Trypanosoma cruzi agent-1
<p>Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.</p>Formule :C23H29N3O5Couleur et forme :SolidMasse moléculaire :427.49Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Formule :C17H10ClFN2Couleur et forme :SolidMasse moléculaire :296.73Xeruborbactam
CAS :<p>QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.</p>Formule :C10H8BFO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.98SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Formule :C21H21N5O5SCouleur et forme :SolidMasse moléculaire :455.49RSV-IN-7
CAS :<p>RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) .</p>Formule :C27H22F3N7O3Couleur et forme :SolidMasse moléculaire :549.50GR 122222X
CAS :<p>GR 122222X is an inhibitor of topoisomerase II.</p>Formule :C26H35N5O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.65DNA crosslinker 6
CAS :<p>DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.</p>Formule :C19H21N7OCouleur et forme :SolidMasse moléculaire :363.42Cap-dependent endonuclease-IN-17
CAS :<p>CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.</p>Formule :C24H20F2N3O7PSCouleur et forme :SolidMasse moléculaire :563.47Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Formule :C24H24FN5O7SCouleur et forme :SolidMasse moléculaire :545.54TAN-1057C
CAS :<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Formule :C13H25N9O3Couleur et forme :SolidMasse moléculaire :355.4Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formule :C19H18F4O2Couleur et forme :SolidMasse moléculaire :354.34Palmitanilide
CAS :<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Formule :C22H37NOCouleur et forme :SolidMasse moléculaire :331.535PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Formule :C28H27ClN4O4Couleur et forme :SolidMasse moléculaire :518.992,5-Di-tert-butyl-1,4-benzoquinone
CAS :<p>2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.</p>Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31SARS-CoV-2 Mpro-IN-34
<p>SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.</p>Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Formule :C27H30N4O5Couleur et forme :SolidMasse moléculaire :490.55Cefoxazole
CAS :<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formule :C21H18ClN3O7SCouleur et forme :SolidMasse moléculaire :491.902AN-12-H5
CAS :<p>AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.</p>Formule :C24H23N3O4S3Couleur et forme :SolidMasse moléculaire :513.65NFC nitro probe 1
CAS :<p>NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.</p>Formule :C19H19NO6Couleur et forme :SolidMasse moléculaire :357.357Antibacterial agent 278
CAS :<p>Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.</p>Formule :C24H17ClF2N4O3Couleur et forme :SolidMasse moléculaire :482.87MA220607
CAS :<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Formule :C34H38INCouleur et forme :SolidMasse moléculaire :587.58WM382
CAS :<p>WM382, a potent dual PMIX/X inhibitor, has IC50s of 1.4 nM/0.03 nM and effective against various malaria stages.</p>Formule :C29H36N4O4Couleur et forme :SolidMasse moléculaire :504.62NDM-1 inhibitor-7
CAS :<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Formule :C9H10N2OS2Couleur et forme :SolidMasse moléculaire :226.319NSC 641396
CAS :<p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>Formule :C18H13NO3Couleur et forme :SolidMasse moléculaire :291.301Anti-Influenza agent 3
<p>Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).</p>Formule :C16H22ClNOSCouleur et forme :SolidMasse moléculaire :311.87FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Formule :C21H16ClF2NO2Couleur et forme :SolidMasse moléculaire :387.81WRN inhibitor 7
CAS :<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Formule :C27H23N3O6Couleur et forme :SolidMasse moléculaire :485.49BDM91288
CAS :<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Formule :C17H22ClN5Couleur et forme :SolidMasse moléculaire :331.84Rupintrivir
CAS :<p>Rupintrivirvr (AG7088) is a mimetic peptide inhibitor of rhinovirus (HRV) 3C cysteine protease with antiviral activity for the study of viral infections.</p>Formule :C31H39FN4O7Degré de pureté :97.72% - 99.35%Couleur et forme :SolidMasse moléculaire :598.66JTK-109
CAS :<p>JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.</p>Formule :C37H33ClFN3O4Degré de pureté :98.48% - 99.68%Couleur et forme :SolidMasse moléculaire :638.13Eravacycline dihydrochloride
CAS :<p>Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).</p>Formule :C27H33Cl2FN4O8Degré de pureté :94.59% - 95%Couleur et forme :SolidMasse moléculaire :631.48Vaniprevir
CAS :<p>Vaniprevir is a competitive HCV NS3/4A protease inhibitor, an antiviral(hepatitis C virus) drug that acts directly and blocks the viral replication process.</p>Formule :C38H55N5O9SDegré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :757.94LeuRS-IN-1 hydrochloride
CAS :<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Formule :C10H14BCl2NO3Degré de pureté :97.34% - 99.61%Couleur et forme :SolidMasse moléculaire :277.94CTPS1-IN-1
CAS :<p>CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.</p>Formule :C21H22N6O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :486.57D75-4590
CAS :<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Formule :C21H27N5Degré de pureté :98.56% - 98.85%Couleur et forme :SolidMasse moléculaire :349.47Tigemonam
CAS :<p>Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.</p>Formule :C12H15N5O9S2Degré de pureté :99.03% - >99.99%Couleur et forme :SolidMasse moléculaire :437.41Cap-dependent endonuclease-IN-1
CAS :<p>Cap-dependent endonuclease-IN-1: potent, oral inhibitor with antiviral properties against influenza.</p>Formule :C27H22F2N2O6SDegré de pureté :98.88% - 99.09%Couleur et forme :SolidMasse moléculaire :540.54CCF0058981
CAS :<p>CCF0058981: noncovalent inhibitor for SARS-CoV-2 & -1 proteases; IC50s: 68 nM (SC2) & 19 nM (SC1). Potential COVID-19 research use.</p>Formule :C24H19ClN6ODegré de pureté :98.94%Couleur et forme :SoildMasse moléculaire :442.9HRO761
CAS :<p>HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.</p>Formule :C31H31ClF3N9O5Degré de pureté :98.74% - 99.62%Couleur et forme :SolidMasse moléculaire :702.08IDX184
CAS :<p>IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3</p>Formule :C25H35N6O9PSDegré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :626.62SR 11302
CAS :<p>SR 11302 is an inhibitor of activator protein-1 (AP-1).</p>Formule :C26H32O2Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :376.53Durlobactam sodium salt
CAS :<p>Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.</p>Formule :C8H10N3NaO6SDegré de pureté :97.01% - 99.03%Couleur et forme :SolidMasse moléculaire :299.23FGI-106 tetrahydrochloride
CAS :<p>FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola</p>Formule :C28H42Cl4N6Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :604.48Reutericyclin
CAS :<p>Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.</p>Formule :C20H31NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.46Haloxon
CAS :<p>Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.</p>Formule :C14H14Cl3O6PCouleur et forme :SolidMasse moléculaire :415.59L-Eflornithine monohydrochloride
CAS :<p>L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine.</p>Formule :C6H13ClF2N2O2Couleur et forme :SolidMasse moléculaire :218.632'-Hydroxy-4'-methylacetophenone
CAS :<p>2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.</p>Formule :C9H10O2Degré de pureté :99.88%Couleur et forme :Black LiquidMasse moléculaire :150.17α-Terpineol
CAS :<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.255'-O-TBDMS-dT
CAS :<p>5’-O-TBDMS-dT is a nucleoside with protective and modification effects.</p>Formule :C16H28N2O5SiCouleur et forme :SolidMasse moléculaire :356.49FtsZ-IN-10
CAS :<p>Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.</p>Formule :C15H13ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.79Hexahydrohippuric acid
CAS :<p>Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.</p>Formule :C9H15NO3Couleur et forme :SolidMasse moléculaire :185.2232-Mercaptopyridine N-oxide sodium
CAS :<p>2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.</p>Formule :C5H4NNaOSCouleur et forme :SolidMasse moléculaire :149.14Pulcherriminic acid
CAS :<p>Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.</p>Formule :C12H20N2O4Couleur et forme :SolidMasse moléculaire :256.30Stearyl gallate
CAS :<p>Stearyl gallate is a useful organic compound for research related to life sciences. The catalog number is T65655 and the CAS number is 10361-12-3.</p>Formule :C25H42O5Couleur et forme :SolidMasse moléculaire :422.606Cyclotriazadisulfonamide
CAS :<p>Cyclotriazadisulfonamide (CADA) is a specific inhibitor of HIV entry that targets CD4 by preventing the co-translational translocation of human CD4 (huCD4) into the endoplasmic reticulum (ER) lumen through a signal peptide (SP)-dependent mechanism.</p>Formule :C31H39N3O4S2Couleur et forme :SolidMasse moléculaire :581.79PqsR/LasR-IN-1
CAS :<p>PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).</p>Formule :C24H20ClNO3Couleur et forme :SolidMasse moléculaire :405.875'-O-DMT-N6-ibu-dA
CAS :<p>5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.</p>Formule :C35H37N5O6Couleur et forme :SolidMasse moléculaire :623.71NSC639828
CAS :<p>NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.</p>Formule :C18H13BrClN5O3Couleur et forme :SolidMasse moléculaire :462.691-Naphthalenemethanol
CAS :<p>1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.</p>Formule :C11H10OCouleur et forme :SolidMasse moléculaire :158.2Tetraconazole
CAS :<p>Tetraconazole is an agent of pesticides.</p>Formule :C13H11Cl2F4N3OCouleur et forme :Liquid ViscousMasse moléculaire :372.14Ulifloxacin
CAS :<p>Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.</p>Formule :C16H16FN3O3SCouleur et forme :SolidMasse moléculaire :349.38Policresulen
CAS :<p>Policresulen is a useful organic compound for research related to life sciences. The catalog number is T66902 and the CAS number is 101418-00-2.</p>Formule :C8H10O5SCouleur et forme :SolidMasse moléculaire :218.22Lenampicillin hydrochloride
CAS :<p>Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin </p>Formule :C21H24ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.95Erythromycylamine
CAS :<p>Erythromycylamine is a useful organic compound for research related to life sciences. The catalog number is T64443 and the CAS number is 26116-56-3.</p>Formule :C37H70N2O12Couleur et forme :SolidMasse moléculaire :734.969BMS-378806
<p>BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.</p>Formule :C22H22N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.43Pseudomonic acid C
CAS :<p>Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.</p>Formule :C26H44O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.62Darobactin
CAS :<p>Darobactin is an antibiotic effective against critical Gram-negative pathogens, demonstrating activity both in vitro and in animal infection models [1].</p>Formule :C47H55N11O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :966.01ABT-072 potassium trihydrate
CAS :<p>ABT-072, also known as potassium trihydrate, is a highly effective non-nucleoside inhibitor of the HCV NS5B polymerase, administered orally. This compound exhibits potent activity against HCV GT1a (with an EC50 of 1 nM) and HCV GT1b (with an EC50 of 0.3 nM).</p>Formule :C24H32KN3O8SCouleur et forme :SolidMasse moléculaire :561.69
