Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.943 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(561 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(297 produits)
Affichez 12 plus de sous-catégories
5398 produits trouvés pour "Neuroscience"
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Eslicarbazepine
CAS :<p>Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.</p>Formule :C15H14N2O2Degré de pureté :99.97%Couleur et forme :Off-White SolidMasse moléculaire :254.28Biphenylindanone A
CAS :<p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>Formule :C30H30O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.56Octahydroaminoacridine succinate
CAS :<p>Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.</p>Formule :C17H24N2O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :320.38ADX71441
CAS :<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Formule :C19H15ClF2N4O4Couleur et forme :SolidMasse moléculaire :436.8Adipiplon
CAS :<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Formule :C18H18FN7Couleur et forme :SolidMasse moléculaire :351.38CGP 64213
CAS :<p>CGP 64213 is a GABAb receptor agonist.</p>Formule :C26H36IN2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.45(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Formule :C16H22ClN3O2Couleur et forme :SolidMasse moléculaire :323.82CGP 54626 hydrochloride
CAS :<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Formule :C18H29Cl3NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.76AMG-8718
CAS :<p>AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.</p>Formule :C25H19FN4O3Couleur et forme :SolidMasse moléculaire :442.44UNC9994
CAS :<p>UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.</p>Formule :C21H22Cl2N2OSCouleur et forme :SolidMasse moléculaire :421.38NAS-181
CAS :<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Formule :C20H30N2O7SCouleur et forme :SolidMasse moléculaire :442.53Afizagabar
CAS :<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Formule :C19H12FN3O2SCouleur et forme :SolidMasse moléculaire :365.38AChE-IN-44
CAS :<p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>Formule :C31H38ClN3OS2Couleur et forme :SolidMasse moléculaire :568.24Nemonapride
CAS :<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Formule :C21H26ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.9ASS234
CAS :<p>ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.</p>Formule :C29H37N3OCouleur et forme :SolidMasse moléculaire :443.62VU 0255035
CAS :<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Formule :C18H20N6O3S2Degré de pureté :98.09% - 98.1%Couleur et forme :SolidMasse moléculaire :432.52Yhhu-3792 hydrochloride
CAS :<p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>Formule :C24H25ClN4O2Couleur et forme :SolidMasse moléculaire :436.93β-Secretase Inhibitor IV
CAS :<p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>Formule :C31H38N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.72Fosthiazate
CAS :<p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>Formule :C9H18NO3PS2Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :283.35Cyclophostin
CAS :<p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>Formule :C8H11O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.14cis-PDA
CAS :<p>cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.</p>Formule :C7H11NO4Degré de pureté :98.71%Couleur et forme :White SolidMasse moléculaire :173.17LY3202626
CAS :<p>LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.</p>Formule :C22H20F2N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.51Indeloxazine hydrochloride
CAS :<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Formule :C14H18ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.75CGP-54626 free base
CAS :CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Formule :C18H28Cl2NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.3GYKI-46903 HCl
CAS :<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Formule :C17H21ClFNO2Couleur et forme :SolidMasse moléculaire :325.81MAO-B-IN-1
CAS :<p>MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.</p>Formule :C16H14F3N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.36UNC9994 hydrochloride
CAS :<p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>Formule :C21H23Cl3N2OSCouleur et forme :SolidMasse moléculaire :457.84Frovatriptan
CAS :<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formule :C14H17N3OCouleur et forme :SolidMasse moléculaire :243.3Mesembrine
CAS :<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Formule :C17H23NO3Couleur et forme :SolidMasse moléculaire :289.37ABT-418 hydrochloride
CAS :<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Formule :C9H15ClN2OCouleur et forme :SolidMasse moléculaire :202.68GR 127935 hydrochloride
CAS :<p>5-HT1B/1D receptor antagonist</p>Formule :C29H32ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.05Dothiepin
CAS :<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formule :C19H21NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.44NAS181
CAS :<p>rat 5-HT1B receptor antagonist</p>Formule :C21H34N2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.63Brasofensine sulfate
CAS :<p>Brasofensine sulfate is a dopamine reuptake inhibitor.</p>Formule :C16H22Cl2N2O5SCouleur et forme :SolidMasse moléculaire :425.33L 663581
CAS :<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Formule :C17H16ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.79Lanabecestat
CAS :<p>Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.</p>Formule :C26H28N4ODegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :412.53JNJ-46281222
CAS :<p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>Formule :C23H25F3N4Couleur et forme :SolidMasse moléculaire :414.47Flesinoxan
CAS :<p>Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).</p>Formule :C22H26FN3O4Couleur et forme :SolidMasse moléculaire :415.46PQM130
CAS :<p>PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.</p>Formule :C23H27NO4Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :381.46Wf-516
CAS :<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Formule :C25H25Cl2N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.39(±)-Fabesetron hydrochloride
CAS :<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Formule :C18H20ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.82AZ10606120 dihydrochloride
CAS :<p>AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors,</p>Formule :C25H36Cl2N4O2Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :495.484-Chloro-L-phenylalanine
CAS :<p>4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).</p>Formule :C9H10ClNO2Degré de pureté :99.76% - 99.96%Couleur et forme :SolidMasse moléculaire :199.63Thioflosulide
CAS :<p>Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.</p>Formule :C16H13F2NO3S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :369.41PZ-II-029
CAS :<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Formule :C18H15N3O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :321.33Cimicoxib
CAS :<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Formule :C16H13ClFN3O3SDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :381.81VU6005649
CAS :<p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>Formule :C16H12F5N3ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :357.28NO-711ME
CAS :<p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>Formule :C22H24N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :364.44Tematropium
CAS :<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Formule :C21H31NO8SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :457.54BuChE-IN-TM-10
CAS :<p>TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.</p>Formule :C32H38N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :498.66Osemozotan HCl
CAS :<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Formule :C19H22ClNO5Degré de pureté :98.87% - 99.63%Couleur et forme :SolidMasse moléculaire :379.84γ-Secretase-IN-1
CAS :<p>γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.</p>Formule :C27H24F2N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :490.5Philanthotoxin 74 dihydrochloride
CAS :<p>Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.</p>Formule :C24H44Cl2N4O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :507.54Dalzanemdor
CAS :<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Formule :C27H43F3O2Degré de pureté :98.2% - >99.99%Couleur et forme :SolidMasse moléculaire :456.62AMPA receptor modulator-1
CAS :<p>AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.</p>Formule :C16H11ClF3NO2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :341.71Atabecestat
CAS :<p>Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.</p>Formule :C18H14FN5OSDegré de pureté :99.21% - 99.77%Couleur et forme :SolidMasse moléculaire :367.4Gossypolone
CAS :<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Formule :C30H26O10Degré de pureté :96.66%Couleur et forme :SolidMasse moléculaire :546.52Rislenemdaz
CAS :<p>Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).</p>Formule :C19H23FN4O2Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :358.41Didesmethyl cariprazine
CAS :<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Formule :C19H28Cl2N4ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :399.36AMPA receptor antagonist-3
CAS :<p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>Formule :C20H19N5O2SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :393.46WAY-607695
CAS :<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Formule :C13H12FNO2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :233.24R-(+)-EU-1180-453
CAS :<p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>Formule :C22H21FN2O3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :380.41CGP 78608 hydrochloride
CAS :<p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>Formule :C11H14BrClN3O5PDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :414.58TZ3O
CAS :<p>TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.</p>Formule :C18H13NO4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :339.37VU6004909
CAS :<p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>Formule :C21H15FN2O4Degré de pureté :96.68% - 98.44%Couleur et forme :SolidMasse moléculaire :378.35JNJ-42253432
CAS :<p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>Formule :C28H38N4ODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :446.63SB 216641 hydrochloride
CAS :<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Formule :C28H31ClN4O4Degré de pureté :98.06% - 99.23%Couleur et forme :SolidMasse moléculaire :523.02SB-616234-A
CAS :<p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>Formule :C32H36ClN5O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :574.11Lumateperone
CAS :<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formule :C24H28FN3ODegré de pureté :99.68% - 99.91%Couleur et forme :SolidMasse moléculaire :393.5BMS-986176
CAS :<p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>Formule :C19H23F4N3ODegré de pureté :98.58% - 98.7%Couleur et forme :SolidMasse moléculaire :385.4PXS-5153A
CAS :<p>PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.</p>Formule :C20H25Cl2FN4O2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :475.41PXS-5120A
CAS :<p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>Formule :C22H25ClFN3O4SDegré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :481.97MDR-1339
CAS :<p>MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.</p>Formule :C20H22O4Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :326.39γ-Secretase modulator 11 hydrochloride
CAS :<p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>Formule :C28H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :520.96PTCA
CAS :<p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>Formule :C10H5Cl2NO2SCouleur et forme :SolidMasse moléculaire :274.123S-8510 phosphate
CAS :<p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>Formule :C12H13N4O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.23BChE-IN-38
CAS :<p>BChE-IN-38 (compound 13) is a potent BChE inhibitor, with Ki values of 62.05, 28.78, 14.09, and 1.15 nM for hCAI, hCAII, AChE, and BChE, respectively. BChE-IN-38 also demonstrates cytotoxic activity.</p>Formule :C27H20N4Couleur et forme :SolidMasse moléculaire :400.474Serotonin maleate
CAS :<p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>Formule :C14H16N2O5Couleur et forme :SolidMasse moléculaire :292.287Metoquizine
CAS :<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48AAK1-IN-2 TFA
<p>AAK1-IN-2 TFA (compound (S)-31) is a selective and potent AAK1 inhibitor (IC50: 5.8 nM) that can cross the blood-brain barrier.</p>Formule :C24H22F6N4O4Couleur et forme :SolidMasse moléculaire :544.45Terguride
CAS :<p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>Formule :C20H28N4OCouleur et forme :SolidMasse moléculaire :340.465-HT6R/MAO-B modulator 1
<p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>Formule :C33H38N4O3SCouleur et forme :SolidMasse moléculaire :570.74Beloxepin
CAS :<p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>Formule :C19H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.38GABA-IN-4
CAS :<p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>Formule :C17H13ClN2O2Couleur et forme :SolidMasse moléculaire :312.75(E)-CHBO4
CAS :<p>(E)-CHBO4 is an MAO-B inhibitor with an IC50 value of 0.023 μM, making it a potential candidate for research into Parkinson's disease treatment.</p>Formule :C15H10BrFOCouleur et forme :SolidMasse moléculaire :305.142SZ1676
CAS :<p>SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.</p>Formule :C37H59BrN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :707.78(R)-Norfluoxetine
CAS :<p>(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.</p>Formule :C16H16F3NOCouleur et forme :SolidMasse moléculaire :295.299(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Formule :C10H19ClNO1·5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :244.78AChE-IN-84
CAS :<p>AChE-IN-84 (compound 21) is an inhibitor of AChE.</p>Formule :C6H15Br2NCouleur et forme :SolidMasse moléculaire :260.998SB 243213 dihydrochloride
CAS :<p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>Formule :C22H21Cl2F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.33MAO-B-IN-10
<p>MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.</p>Formule :C23H26N2O4Couleur et forme :SolidMasse moléculaire :394.46Dual AChE-MAO B-IN-1
<p>Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.</p>Formule :C23H25F2NO4Couleur et forme :SolidMasse moléculaire :417.45P2X4 antagonist-1
CAS :<p>P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.</p>Formule :C20H15Cl3N2O4SDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :485.77AZD 2066 hydrate
<p>AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].</p>Formule :C19H18ClN5O3Couleur et forme :SolidMasse moléculaire :386.33AChE/BChE-IN-3 hydrochloride
<p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>Formule :C15H25ClN2O3Couleur et forme :SolidMasse moléculaire :316.82(S)-YNT-3708
CAS :<p>(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.</p>Formule :C35H36N4O6SCouleur et forme :SolidMasse moléculaire :640.749PF-06751979
CAS :<p>PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).</p>Formule :C18H19F2N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.5AChE/BChE-IN-19
CAS :<p>AChE/BChE-IN-19 (compound 12) is a nicotinic hydrazine derivative that acts as an inhibitor of AChE (IC50=21.45 nM) and BChE (IC50=18.42 nM), and it is applicable in Alzheimer's disease research.</p>Formule :C26H22N4O3Masse moléculaire :438.48(S)-Praziquantel
CAS :<p>(S)-Praziquantel is the inactive isomer of R-praziquantel.</p>Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.406Remlifanserin
CAS :<p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>Formule :C24H29F2N3O2Couleur et forme :SolidMasse moléculaire :429.50
