récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
1025 produits trouvés pour "récepteur 5-HT"
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ECPLA
CAS :ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formule :C21H25N3OCouleur et forme :SolidMasse moléculaire :335.44isomer-Cilansetron
CAS :isomer-Cilansetron is an isomer of Cilansetron.Formule :C20H21N3ODegré de pureté :99.92% - 99.96%Couleur et forme :SoildMasse moléculaire :319.4meta-Fluoxetine (hydrochloride)
CAS :meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formule :C17H19ClF3NOCouleur et forme :SolidMasse moléculaire :345.7925E-NBOMe hydrochloride
CAS :25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.Formule :C20H28ClNO3Couleur et forme :SolidMasse moléculaire :365.894-hydroxy DiPT hydrochloride
CAS :4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.Formule :C16H25ClN2OCouleur et forme :SolidMasse moléculaire :296.84VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.Couleur et forme :SolidZicronapine fumarate
CAS :Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.Formule :C26H31ClN2O4Couleur et forme :SolidMasse moléculaire :470.99SB656104
CAS :SB656104 is a bioactive chemical.Formule :C25H30ClN3O3SCouleur et forme :SolidMasse moléculaire :488.04Vortioxetine D8
CAS :Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Formule :C18H22N2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.5HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.654-Butyl-α-agarofuran
CAS :4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.Formule :C18H30OCouleur et forme :SolidMasse moléculaire :262.43Ethylpropyltryptamine
CAS :Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Formule :C15H22N2Couleur et forme :SolidMasse moléculaire :230.35Palonosetron N-oxide
CAS :Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.4134-Hydroxy MET
CAS :4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.Formule :C13H18N2OCouleur et forme :SolidMasse moléculaire :218.3PF-03382792
CAS :PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Formule :C23H32FN3O4Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :433.52Brexpiprazole S-oxide D8
CAS :Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.Formule :C25H19D8N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.61Quetiapine-d4 fumarate
CAS :Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.Formule :C25H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.615-HT6 inverse agonist 1
CAS :5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formule :C22H22Cl2FN3O3SCouleur et forme :SolidMasse moléculaire :498.4LP-20
CAS :LP-20 is a bioactive chemical.Formule :C17H20N2OCouleur et forme :SolidMasse moléculaire :268.35Cabergoline
CAS :Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.Formule :C26H37N5O2Degré de pureté :97.69% - 99.86%Couleur et forme :White Crystalline SolidMasse moléculaire :451.6MRS8209
MRS8209 is an antagonist of the serotonin receptor (serotonin receptor), with a Ki value of 4.27 nM specifically for 5-HT2BR. It provides protective effects on pulmonary airway opening pressure (PAO) and is applicable in pulmonary fibrosis studies.Formule :C17H19IN6O2Couleur et forme :SolidMasse moléculaire :466.276Eletriptan
CAS :Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.Formule :C22H26N2O2SCouleur et forme :SolidMasse moléculaire :382.524-Hydroxy MPT
CAS :4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.325-HT6 agonist 1
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting plateletFormule :C17H22Cl2N6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.37Tiflucarbine
CAS :Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormule :C16H17FN2SDegré de pureté :97.71%Couleur et forme :SolidMasse moléculaire :288.38Org 13011
CAS :Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Formule :C18H25F3N4ODegré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :370.41Ref: TM-T28258L
1mg109,00€5mg261,00€1mL*10mM (DMSO)266,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€1-Phenylbiguanide HCl
CAS :Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.Formule :C8H12ClN5Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :213.67Granisetron
CAS :Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
Formule :C18H24N4OCouleur et forme :SolidMasse moléculaire :312.41Aramisulpride
CAS :Aramisulpride is a dual antagonist of the dopamine D2 receptor and serotonin receptor, primarily utilized for investigating metabolic disorders.Formule :C17H27N3O4SCouleur et forme :SolidMasse moléculaire :369.48Eplivanserin (mixture)
CAS :Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,Formule :C19H21FN2O2Couleur et forme :SolidMasse moléculaire :328.387SB-200646A
CAS :SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.Formule :C15H15ClN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.763-Hydroxy agomelatine
CAS :3-Hydroxy agomelatine (3-Hydroxyagomelatine) is a 5-HT2C receptor antagonist used in the study of neurological disorders.Formule :C15H17NO3Couleur et forme :SolidMasse moléculaire :259.3Thioridazine
CAS :Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.Formule :C21H26N2S2Couleur et forme :SolidMasse moléculaire :370.57Altanserin
CAS :Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.Formule :C22H22FN3O2SCouleur et forme :SolidMasse moléculaire :411.49Setiptiline maleate
CAS :Setiptiline maleate is a norepinephrine reuptake inhibitor, 2-adrenergic receptor antagonist, H1 receptor inverse agonist, 5-HT serotonin receptor antagonist.Formule :C23H23NO4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :377.43cis-(Z)-Flupentixol dihydrochloride
CAS :cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.Formule :C23H27Cl2F3N2OSDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :507.44Fluvoxamine
CAS :Fluvoxamine (DU-23000) is a selective, orally available 5-HT and serotonin reuptake inhibitor (SSRI) exhibiting antidepressant effects.Formule :C15H21F3N2O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :318.33SB-269970 hydrochloride
CAS :SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivityFormule :C18H28N2O3S·HClDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :388.95Agomelatine (L(+)-Tartaric acid)
CAS :Agomelatine (L(+)-Tartaric acid) is an MT1/MT2 agonist and selective 5-HT2C antagonist, supporting melatonergic and serotonergic signaling studies in neuroscience.Formule :C19H23NO8Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :393.39SB-277011 hydrochloride
CAS :SB-277011 hydrochloride (SB-277011A hydrochloride) is a D3R antagonist, which induces delayed ejaculation in rats.Formule :C28H31ClN4ODegré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :475.03Cefaclor
CAS :Cefaclor (Panoral) is a cephalosporin antibiotic.Formule :C15H14ClN3O4SDegré de pureté :99.03% - 99.98%Couleur et forme :SolidMasse moléculaire :367.81Ziprasidone D8
CAS :Ziprasidone D8, deuterium-labeled, is a potent antipsychotic, antagonizing 5-HT and dopamine receptors.Formule :C21H21ClN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.99(R)-Praziquantel-d11
CAS :(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel.Formule :C19H24N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.47Olanzapine D3
CAS :Olanzapine D3 is the deuterium labeled Olanzapine.Formule :C17H20N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.45Sumatriptan
CAS :Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in acute migraine and acute myocardial infarction.Formule :C14H21N3O2SDegré de pureté :99.93%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :295.4Aripiprazole (D8)
CAS :Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).Formule :C23H27Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.44Spiroxatrine
CAS :Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.Formule :C22H25N3O3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :379.45Agomelatine-d6
CAS :Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.Formule :C15H17NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :249.34Asenapine hydrochloride
CAS :Asenapine hydrochloride (Org 5222 hydrochloride) is an antagonist of 5-hydroxytryptamine, adrenergic, dopamine, and histamine receptors with antipsychotic effects.Formule :C17H17Cl2NOCouleur et forme :SolidMasse moléculaire :322.23Quetiapine-d4 hemifumarate
CAS :Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with ntidepressant and anxiolytic.Formule :C25H29N3O6SDegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :503.61
