Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1428 produits trouvés pour "Autophagie"
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TWS119
CAS :<p>TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation</p>Formule :C18H14N4O2Degré de pureté :98.14% - 99.63%Couleur et forme :SolidMasse moléculaire :318.33Rutin hydrate
CAS :<p>Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.</p>Formule :C27H32O17Degré de pureté :97.23%Couleur et forme :SolidMasse moléculaire :628.53Crizotinib hydrochloride
CAS :<p>Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)</p>Formule :C21H23Cl3FN5ODegré de pureté :98.73% - 98.87%Couleur et forme :SolidMasse moléculaire :486.8Danusertib
CAS :<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.553-Methyladenine
CAS :<p>3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).</p>Formule :C6H7N5Degré de pureté :98.02% - 99.65%Couleur et forme :SolidMasse moléculaire :149.15WYC-209
CAS :<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Formule :C20H20N2O3SDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :368.45Salirasib
CAS :<p>Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.</p>Formule :C22H30O2SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :358.54MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formule :C26H37ClN6O2Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :501.07Afatinib Dimaleate
CAS :<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Formule :C32H33ClFN5O11Degré de pureté :98.11% - 99.87%Couleur et forme :SolidMasse moléculaire :718.08Liensinine diperchlorate
CAS :<p>Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.</p>Formule :C37H44Cl2N2O14Degré de pureté :99.8% - ≥95%Couleur et forme :SolidMasse moléculaire :811.67TA-02
CAS :<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Formule :C20H13F2N3Degré de pureté :99.35% - 99.79%Couleur et forme :SolidMasse moléculaire :333.33Sepantronium bromide
CAS :<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Formule :C20H19BrN4O3Degré de pureté :99.68% - 99.85%Couleur et forme :SolidMasse moléculaire :443.26LY294002
CAS :<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34Bafilomycin A1
CAS :<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Formule :C35H58O9Degré de pureté :95.87% - 99.36%Couleur et forme :SolidMasse moléculaire :622.83PFI-1
CAS :<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formule :C16H17N3O4SDegré de pureté :98.74% - 99.19%Couleur et forme :SolidMasse moléculaire :347.39Belinostat
CAS :<p>Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.</p>Formule :C15H14N2O4SDegré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :318.353'-Hydroxypterostilbene
CAS :<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formule :C16H16O4Degré de pureté :98.25% - 99.19%Couleur et forme :SolidMasse moléculaire :272.3BIIB021
CAS :<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Formule :C14H15ClN6ODegré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :318.76Quisinostat
CAS :<p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47Sapanisertib
CAS :<p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>Formule :C15H15N7ODegré de pureté :99.19% - >99.99%Couleur et forme :SolidMasse moléculaire :309.33Isodeoxyelephantopin
CAS :<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Formule :C19H20O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :344.36Veliparib
CAS :<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Formule :C13H16N4ODegré de pureté :98.66% - 99%Couleur et forme :SolidMasse moléculaire :244.29Pyriproxyfen
CAS :<p>Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.</p>Formule :C20H19NO3Degré de pureté :99.83%Couleur et forme :Solid CompactMasse moléculaire :321.37Flavopiridol hydrochloride
CAS :<p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>Formule :C21H21Cl2NO5Degré de pureté :98.87% - 99.88%Couleur et forme :SolidMasse moléculaire :438.3Orthanilamide
CAS :<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Formule :C6H8N2O2SDegré de pureté :99.72% - 99.96%Couleur et forme :White To Pale Cream Crystalline Powder Or CrystalsMasse moléculaire :172.2AGN 193109
CAS :<p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>Formule :C28H24O2Degré de pureté :99.87% - 99.89%Couleur et forme :SolidMasse moléculaire :392.49MPP+ iodide
CAS :<p>MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.</p>Formule :C12H12INDegré de pureté :99.49% - 99.96%Couleur et forme :SolidMasse moléculaire :297.13Genistein
CAS :<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Formule :C15H10O5Degré de pureté :98.22% - 99.64%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24(1E,6E)-Bis(demethoxy)curcumin
CAS :<p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>Formule :C19H16O4Degré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :308.33GSK2578215A
CAS :<p>GSK2578215A is a potent and selective LRRK2 kinase inhibitor.</p>Formule :C24H18FN3O2Degré de pureté :99.57% - 99.94%Couleur et forme :SolidMasse moléculaire :399.42Imatinib
CAS :<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Formule :C29H31N7ODegré de pureté :99.42% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Demethoxycurcumin
CAS :<p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>Formule :C20H18O5Degré de pureté :94.54% - 99.86%Couleur et forme :SolidMasse moléculaire :338.35Aloperine
CAS :<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Formule :C15H24N2Degré de pureté :98% - 99.88%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :232.36Arglabin
CAS :<p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>Formule :C15H18O3Degré de pureté :98.97% - 99.62%Couleur et forme :SolidMasse moléculaire :246.3Bilobalide
CAS :<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Formule :C15H18O8Degré de pureté :98.81% - 99.92%Couleur et forme :White SolidMasse moléculaire :326.3Apocynin
CAS :<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Formule :C9H10O3Degré de pureté :99.71% - 99.98%Couleur et forme :Yellowish To Brown PowderMasse moléculaire :166.17HA15
CAS :<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Formule :C23H22N4O3S2Degré de pureté :99.77% - 99.86%Couleur et forme :SolidMasse moléculaire :466.58Tomatidine
CAS :<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Formule :C27H45NO2Degré de pureté :99.94% - 99.98%Couleur et forme :SolidMasse moléculaire :415.65ISRIB (trans-isomer)
CAS :<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Formule :C22H24Cl2N2O4Degré de pureté :97.86% - 99.27%Couleur et forme :SolidMasse moléculaire :451.34Binimetinib
CAS :<p>Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.</p>Formule :C17H15BrF2N4O3Degré de pureté :98.03% - >99.99%Couleur et forme :SolidMasse moléculaire :441.23Reparixin
CAS :<p>Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.</p>Formule :C14H21NO3SDegré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :283.39GNE-7915
CAS :<p>GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.</p>Formule :C19H21F4N5O3Degré de pureté :98% - ≥95%Couleur et forme :SolidMasse moléculaire :443.4Daurisoline
CAS :<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formule :C37H42N2O6Degré de pureté :98% - 99.96%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74Bigelovin
CAS :<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Formule :C17H20O5Degré de pureté :99.61% - 99.72%Couleur et forme :SolidMasse moléculaire :304.34Britannin
CAS :<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formule :C19H26O7Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :366.41Verteporfin
CAS :<p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>Formule :C41H42N4O8Degré de pureté :95.37% - 99.82%Couleur et forme :Dark Green To Black SolidMasse moléculaire :718.79Ralimetinib dimesylate
CAS :<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Formule :C24H29FN6·2CH4O3SDegré de pureté :98% - 99.38%Couleur et forme :SolidMasse moléculaire :612.74Hydroxyprogesterone caproate
CAS :<p>Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.</p>Formule :C27H40O4Degré de pureté :99.70%Couleur et forme :White Or Almost White Crystalline PowerMasse moléculaire :428.60Tizoxanide
CAS :<p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>Formule :C10H7N3O4SDegré de pureté :98.89% - 99.28%Couleur et forme :SolidMasse moléculaire :265.25Bardoxolone Methyl
CAS :<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Formule :C32H43NO4Degré de pureté :97.81% - 99.09%Couleur et forme :SolidMasse moléculaire :505.69
