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DUB

DUB

Les inhibiteurs de déubiquitinases (DUB) ciblent les enzymes qui retirent les molécules d'ubiquitine des protéines, régulant ainsi la stabilité, la localisation et l'activité des protéines dans la cellule. Les déubiquitinases jouent un rôle essentiel dans divers processus cellulaires, notamment la régulation du cycle cellulaire, la réparation de l'ADN et les réponses immunitaires. La dérégulation de l'activité des DUB est liée au cancer, aux troubles neurodégénératifs et aux infections virales. Les inhibiteurs de DUB peuvent moduler ces processus, offrant des approches thérapeutiques potentielles pour ces conditions. Chez CymitQuimica, nous proposons des inhibiteurs de DUB pour soutenir vos recherches en homéostasie des protéines, en oncologie et en neurobiologie.

84 produits trouvés pour "DUB"

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  • IU1-47

    CAS :
    <p>IU1-47 是一种特异性 USP14抑制剂,IC50为 0.6 μM。它诱导培养的神经元中 tau 蛋白降解。它抑制 IsoT/USP5, IC50为 20 μM。</p>
    Formule :C19H23ClN2O
    Degré de pureté :98.94%
    Couleur et forme :Solid
    Masse moléculaire :330.85
  • C527

    CAS :
    <p>C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).</p>
    Formule :C17H8FNO3
    Degré de pureté :97.22%
    Couleur et forme :Solid
    Masse moléculaire :293.25
  • HBX 19818

    CAS :
    <p>HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).</p>
    Formule :C25H28ClN3O
    Degré de pureté :97.71%
    Couleur et forme :Solid
    Masse moléculaire :421.96
  • MF-094

    CAS :
    <p>MF-094 is a selective USP30 inhibitor with IC50 of 0.12 μM. MF-094 can increase protein ubiquitination and accelerate mitophagy.Cost-effective and quality-assured.</p>
    Formule :C30H37N3O4S
    Degré de pureté :99.93%
    Couleur et forme :Solid
    Masse moléculaire :535.7
  • Subquinocin


    <p>Subquinocin is a CYLD inhibitor that suppresses deubiquitinating enzymes (DUB) of the USP family. By inhibiting CYLD, Subquinocin enhances the activation of the NF-κB and IFN pathways. Additionally, Subquinocin facilitates the activation of IRF3 and/or IRF7 in the RIG-I-mediated interferon pathway.</p>
    Formule :C20H27N3O4S
    Couleur et forme :Solid
    Masse moléculaire :405.17223
  • UBD1031


    <p>UBD1031 exhibits strong affinity for the ubiquitin-binding domain (UBD) of USP16, with a dissociation constant (KD) of 48 nM. It inhibits the interaction between USP16 and ISG15, displaying an effective concentration (EC50) of 1.7 nM. UBD1031 can serve as a chemical probe for investigating USP16 UBD.</p>
    Couleur et forme :Odour Solid
  • Ubiquitination Compound Library


    <p>A unique collection of xnum ubiquitination related small chemicals can be used for high throughput and high content screening;</p>
    Couleur et forme :Odour Solid
  • BAY-728


    <p>BAY-728 serves as a negative control for BAY-805, a potent and selective inhibitor of USP21 [1].</p>
    Formule :C24H28F3N5O2S
    Couleur et forme :Solid
    Masse moléculaire :507.57
  • OTUB1/USP8-IN-1 HCl


    <p>OTUB1/USP8-IN-1 HCL is a potent dual inhibitor of OTUB1 and USP8 with potential antitumour activity, inhibiting both OTUB1 and USP8 for leukaemia</p>
    Formule :C22H17Cl2FN2O4
    Degré de pureté :99.92%
    Couleur et forme :Solid
    Masse moléculaire :463.29
  • GK13S


    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formule :C21H22N6O2
    Couleur et forme :Solid
    Masse moléculaire :390.44
  • MS7131


    <p>MS7131 is a DUBTAC inhibitor that recruits USP1. It effectively reduces histone H3 lysine 27 trimethylation and significantly inhibits the proliferation and colony-forming ability of cancer cells.</p>
    Couleur et forme :Odour Solid
  • USP7-IN-16

    CAS :
    <p>USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.</p>
    Formule :C43H45N7O6S
    Couleur et forme :Solid
    Masse moléculaire :787.93
  • USP7-IN-15


    <p>USP7-IN-15 (compound J21) is an inhibitor of USP7, exhibiting an IC50 value of 41.35 ± 2.16 nM.</p>
    Couleur et forme :Odour Solid
  • USP8-IN-2

    CAS :
    <p>USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D.</p>
    Formule :C19H20ClF3N4OS
    Degré de pureté :99.92%
    Couleur et forme :Solid
    Masse moléculaire :444.9
  • USP8-IN-3

    CAS :
    <p>USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D.</p>
    Formule :C18H18F3N5O2S
    Degré de pureté :99.79%
    Couleur et forme :Solid
    Masse moléculaire :425.43
  • OTUB2-IN-1


    <p>OTUB2-IN-1 is an OTUB2 inhibitor with antitumor activity and can be used to study skin cancer and non-small cell lung cancer (NSCLC).</p>
    Formule :C19H18N2O6S2
    Degré de pureté :98.19%
    Couleur et forme :Solid
    Masse moléculaire :434.49
  • JAMM protein inhibitor 2 

    CAS :
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Formule :C21H26N2O2
    Degré de pureté :98.57%
    Couleur et forme :Solid
    Masse moléculaire :338.44
  • USP7-IN-10 hydrochloride


    <p>USP7-IN-10 hydrochloride, also known as compound 1, is a potent inhibitor of the enzyme ubiquitin-specific protease 7 (USP7), exhibiting an IC50 value of 13.39</p>
    Formule :C26H30Cl2N4O3S
    Couleur et forme :Solid
    Masse moléculaire :549.51
  • GK16S


    <p>GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1].</p>
    Formule :C11H15N3O
    Couleur et forme :Soild
    Masse moléculaire :205.12151
  • USP8-IN-1

    CAS :
    <p>USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].</p>
    Formule :C18H21N5O3S
    Degré de pureté :99.07%
    Couleur et forme :Soild
    Masse moléculaire :387.46
  • STD1T

    CAS :
    <p>STD1T is a USP2a inhibitor with anticancer activity that reduces levels of the cell cycle protein D1 protein in HCT116 colon cancer cells.</p>
    Formule :C19H19N3O4S2
    Degré de pureté :98.77%
    Couleur et forme :Solid
    Masse moléculaire :417.5
  • ML364

    CAS :
    <p>ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.</p>
    Formule :C24H18F3N3O3S2
    Degré de pureté :99.35% - >99.99%
    Couleur et forme :Solid
    Masse moléculaire :517.54
  • DUB-IN-3

    CAS :
    <p>DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.</p>
    Formule :C16H9N5O
    Degré de pureté :99.34%
    Couleur et forme :Solid
    Masse moléculaire :287.28
  • GNE-6640

    CAS :
    <p>GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).</p>
    Formule :C20H18N4O
    Degré de pureté :98.64%
    Couleur et forme :Solid
    Masse moléculaire :330.38
  • IU1-248

    CAS :
    <p>IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM[1].</p>
    Formule :C20H23N3O2
    Degré de pureté :99.3%
    Couleur et forme :Solid
    Masse moléculaire :337.42
  • GNE-6776

    CAS :
    <p>GNE-6776 is a selective USP7 inhibitor.</p>
    Formule :C20H20N4O2
    Degré de pureté :96.59% - 98.2%
    Couleur et forme :Solid
    Masse moléculaire :348.4
  • P 22077

    CAS :
    <p>P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also inhibits the closely related USP47.</p>
    Formule :C12H7F2NO3S2
    Degré de pureté :97.9% - 99.58%
    Couleur et forme :Solid
    Masse moléculaire :315.32
  • STAMBP-IN-1

    CAS :
    <p>STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after</p>
    Formule :C27H28N4O4S
    Degré de pureté :99.64%
    Couleur et forme :Solid
    Masse moléculaire :504.6
  • EOAI3402143

    CAS :
    <p>EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.</p>
    Formule :C25H28Cl2N4O3
    Degré de pureté :99.6%
    Couleur et forme :Solid
    Masse moléculaire :503.42
  • TCID

    CAS :
    <p>TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.</p>
    Formule :C9H2Cl4O2
    Degré de pureté :99.34%
    Couleur et forme :Solid
    Masse moléculaire :283.92
  • USP25/28 inhibitor AZ1

    CAS :
    <p>USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective and quality-assured.</p>
    Formule :C17H16BrF4NO2
    Degré de pureté :99.79% - 99.79%
    Couleur et forme :Solid
    Masse moléculaire :422.21
  • USP7-IN-8

    CAS :
    <p>Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM.</p>
    Formule :C21H21N3O2
    Degré de pureté :99.31%
    Couleur et forme :Solid
    Masse moléculaire :347.41
  • XL177A

    CAS :
    <p>XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.</p>
    Formule :C48H57ClN8O5
    Degré de pureté :98.75%
    Couleur et forme :Solid
    Masse moléculaire :861.47
  • USP7/USP47 inhibitor

    CAS :
    <p>USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,</p>
    Formule :C18H11Cl2N3O3S3
    Degré de pureté :98.5% - 98.71%
    Couleur et forme :Solid
    Masse moléculaire :484.4
  • ML-323

    CAS :
    <p>ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal gel-based assays using K63-linked di-Ub and Ub-PCNA as substrates.</p>
    Formule :C23H24N6
    Degré de pureté :99.87% - 99.96%
    Couleur et forme :Solid
    Masse moléculaire :384.48
  • DUB-IN-1

    CAS :
    <p>DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).</p>
    Formule :C20H11N5O
    Degré de pureté :98.33% - 98.96%
    Couleur et forme :Solid
    Masse moléculaire :337.33
  • VLX1570

    CAS :
    <p>VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.</p>
    Formule :C23H17F2N3O6
    Degré de pureté :98.53% - 99.91%
    Couleur et forme :Solid
    Masse moléculaire :469.39
  • P005091

    CAS :
    <p>P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.</p>
    Formule :C12H7Cl2NO3S2
    Degré de pureté :99.53% - 99.87%
    Couleur et forme :Solid
    Masse moléculaire :348.22
  • NSC632839

    CAS :
    <p>NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2</p>
    Formule :C21H22ClNO
    Degré de pureté :99.74% - 99.88%
    Couleur et forme :Solid
    Masse moléculaire :339.86
  • DUB-IN-2

    CAS :
    <p>Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.</p>
    Formule :C15H9N5O
    Degré de pureté :98.96%
    Couleur et forme :Solid
    Masse moléculaire :275.26
  • SJB2-043

    CAS :
    <p>SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).</p>
    Formule :C17H9NO3
    Degré de pureté :98.44%
    Couleur et forme :Solid
    Masse moléculaire :275.26
  • USP1-IN-2

    CAS :
    <p>USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.</p>
    Formule :C26H22F4N6O
    Degré de pureté :99.69% - 99.88%
    Couleur et forme :Solid
    Masse moléculaire :510.486
  • BC-1471

    CAS :
    <p>BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.</p>
    Formule :C27H32N4O4S
    Degré de pureté :99.98%
    Couleur et forme :Solid
    Masse moléculaire :508.63
  • POSH-IN-1

    CAS :
    <p>POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide (e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.</p>
    Formule :C14H8FNO3S
    Degré de pureté :99.29%
    Couleur et forme :Solid
    Masse moléculaire :289.28
  • LCAHA

    CAS :
    <p>LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells.</p>
    Formule :C24H41NO3
    Couleur et forme :Solid
    Masse moléculaire :391.59
  • USP28-IN-3

    CAS :
    <p>USP28-IN-3 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.</p>
    Formule :C23H20Cl2N2O3S
    Degré de pureté :99.92%
    Couleur et forme :Solid
    Masse moléculaire :475.39
  • USP28-IN-4

    CAS :
    <p>USP28-IN-4 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.</p>
    Formule :C22H18Cl2N2O3S
    Degré de pureté :98.48%
    Couleur et forme :Solid
    Masse moléculaire :461.36
  • 8RK64

    CAS :
    <p>8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .</p>
    Formule :C14H16N8O2S
    Couleur et forme :Solid
    Masse moléculaire :360.4
  • USP7-IN-4

    CAS :
    <p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>
    Formule :C29H34N6O3
    Degré de pureté :98.27% - 99.09%
    Couleur et forme :Solid
    Masse moléculaire :514.62
  • FT827

    CAS :
    <p>FT827 is a covalent inhibitor of USP7 that targets the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.</p>
    Formule :C27H28N6O5S
    Degré de pureté :98.76%
    Couleur et forme :Solid
    Masse moléculaire :548.61
  • HBX28258

    CAS :
    <p>HBX28258, a human USP7 inhibitor, binds covalently and selectively deactivates USP7 in colon cancer and kidney cells.</p>
    Formule :C26H30ClN3O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :435.99
  • MF-095

    CAS :
    <p>MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.</p>
    Formule :C27H31N3O4S
    Couleur et forme :Solid
    Masse moléculaire :493.62
  • XL-188

    CAS :
    <p>XL-188: Potent, selective USP7 inhibitor, IC50 = 193 nM (domain), 90 nM (full). Boosts p53, p21; degrades HDM2. Unique among DUB inhibitors.</p>
    Formule :C32H42N6O4
    Couleur et forme :Solid
    Masse moléculaire :574.71
  • Capzimin

    CAS :
    <p>Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.</p>
    Formule :C30H24N6O2S4
    Degré de pureté :98.31% - 99.32%
    Couleur et forme :Solid
    Masse moléculaire :628.81
  • I-138

    CAS :
    <p>I-138 is an orally active and reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells.</p>
    Formule :C26H23F3N6O
    Degré de pureté :99.41%
    Couleur et forme :Solid
    Masse moléculaire :492.5
  • USP28-IN-2

    CAS :
    <p>USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.</p>
    Formule :C23H20Cl2N2O3S
    Couleur et forme :Solid
    Masse moléculaire :475.39
  • GSK2643943A

    CAS :
    <p>GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.</p>
    Formule :C17H12FN3
    Degré de pureté :97.09%
    Couleur et forme :Solid
    Masse moléculaire :277.3
  • SJB3-019A

    CAS :
    <p>SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times</p>
    Formule :C16H8N2O3
    Degré de pureté :99.72%
    Couleur et forme :Solid
    Masse moléculaire :276.25
  • USP30 inhibitor 11

    CAS :
    <p>USP30 inhibitor 11 (USP30-IN-11) is a USP30 inhibitor that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.</p>
    Formule :C17H16N6O2S
    Degré de pureté :98.84% - 99.59%
    Couleur et forme :Solid
    Masse moléculaire :368.41
  • 6RK73

    CAS :
    <p>6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).</p>
    Formule :C13H17N5O2S
    Degré de pureté :99.91%
    Couleur et forme :Solid
    Masse moléculaire :307.37
  • P22074

    CAS :
    <p>P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.</p>
    Formule :C12H9NO3S2
    Degré de pureté :>99.99%
    Couleur et forme :Solid
    Masse moléculaire :279.33
  • USP22-IN-1

    CAS :
    <p>USP22-IN-1 is a ubiquitin-specific peptidase 22 (USP22) inhibitor that can be used to treat proliferative diseases or cancer.</p>
    Formule :C22H18N4
    Degré de pureté :98.2%
    Couleur et forme :Solid
    Masse moléculaire :338.41
  • OTUB1/USP8-IN-1

    CAS :
    <p>OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.</p>
    Formule :C22H16ClFN2O4
    Degré de pureté :98.59%
    Couleur et forme :Soild
    Masse moléculaire :426.83
  • USP1-IN-3

    CAS :
    <p>USP1-IN-3 is a selective inhibitor of USPI that inhibits USPI-UAFI (IC50&lt;30 nM). USP1-IN-3 can be used to study cancer.</p>
    Formule :C27H24F3N7O
    Couleur et forme :Solid
    Masse moléculaire :519.52
  • USP1-IN-5

    CAS :
    <p>USP1-IN-5 (compound 10) is a potent inhibitor of both USP1, with an IC50 of less than 50 nM, and MDA-MB-436 cells, where it also exhibits an IC50 of less than</p>
    Formule :C27H23F3N8O
    Couleur et forme :Solid
    Masse moléculaire :532.52
  • USP7-IN-12

    CAS :
    <p>USP7-IN-12 (compound 1) is a potent, orally active inhibitor of Usp7, exhibiting an IC50 of 3.67 nM and demonstrating antiproliferative activity [1].</p>
    Formule :C29H28ClFN4O2S
    Couleur et forme :Solid
    Masse moléculaire :551.07
  • FT206

    CAS :
    <p>FT206 is a carboxamide inhibitor of ubiquitin-specific protease[1].</p>
    Formule :C25H29N5OS
    Couleur et forme :Solid
    Masse moléculaire :447.6
  • USP7-IN-1

    CAS :
    <p>USP7-IN-1 is a selective and reversible ubiquitin-specific protease 7 (USP7) inhibitor (IC50 = 77 μM).</p>
    Formule :C23H24ClN3O3
    Degré de pureté :99.82%
    Couleur et forme :Solid
    Masse moléculaire :425.91
  • DUB-IN-7

    CAS :
    <p>DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].</p>
    Formule :C17H19N5O
    Couleur et forme :Solid
    Masse moléculaire :309.37
  • FT671

    CAS :
    <p>FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).</p>
    Formule :C24H23F4N7O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :533.48
  • USP7-IN-3

    CAS :
    <p>USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7).</p>
    Formule :C29H31F3N6O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :568.59
  • LDN-91946

    CAS :
    <p>LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).</p>
    Formule :C15H10N2O4S
    Degré de pureté :97.12%
    Couleur et forme :Solid
    Masse moléculaire :314.32
  • USP30 inhibitor 18

    CAS :
    <p>USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.</p>
    Formule :C26H28FN3O4S
    Degré de pureté :99.85%
    Couleur et forme :Solid
    Masse moléculaire :497.58
  • USP1-IN-6

    CAS :
    <p>USP1-IN-6 (Compound 11) functions as a potent USP1 inhibitor, exhibiting an IC50 value of less than 50 nM.</p>
    Formule :C29H27F3N8O
    Couleur et forme :Solid
    Masse moléculaire :560.57
  • CT1113

    CAS :
    <p>CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX</p>
    Formule :C25H29N5O2S
    Couleur et forme :Solid
    Masse moléculaire :463.6
  • USP7-IN-13

    CAS :
    <p>USP7-IN-13 (Compound 101), a USP7 inhibitor, exhibits an IC50 range of 0.2-1 μM and is applicable in researching multiple myeloma [1].</p>
    Formule :C24H28N4O3
    Couleur et forme :Solid
    Masse moléculaire :420.5
  • IMP-1710

    CAS :
    <p>IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.[1]Cost-effective and quality-assured.</p>
    Formule :C23H19N5O
    Degré de pureté :99.3%
    Couleur et forme :Solid
    Masse moléculaire :381.43
  • USP7-IN-10

    CAS :
    <p>USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM.</p>
    Formule :C26H29ClN4O3S
    Couleur et forme :Solid
    Masse moléculaire :513.05
  • FT709

    CAS :
    <p>FT709 is a selective USP9X deubiquitinating enzyme inhibitor (IC50=82 nM) that reduces Makorin and ZNF598 levels, impairing ribosomal quality control pathways.</p>
    Formule :C23H22N4O7S
    Couleur et forme :Solid
    Masse moléculaire :498.51
  • FT3967385


    <p>FT3967385: New USP30 inhibitor boosts mitochondrial ubiquitylation via PINK1-PARKIN.</p>
    Formule :C21H19N5O2
    Couleur et forme :Solid
    Masse moléculaire :373.41
  • USP7-IN-6

    CAS :
    <p>USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).</p>
    Formule :C41H43N7O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :729.89
  • USP7-797

    CAS :
    <p>USP7-797 is a selective non-covalent active site USP7 inhibitor, inhibiting USP7 and ubiquitin binding, with anti-tumor, oral and high efficiency properties.</p>
    Formule :C27H28ClN3O3S
    Degré de pureté :95.90%
    Couleur et forme :Solid
    Masse moléculaire :510.05
  • USP5-IN-1


    <p>USP5-IN-1, a powerful USP5 deubiquitinase inhibitor, selectively binds with 2.8 μM affinity, blocking USP5's di-ubiquitin cleavage.</p>
    Formule :C19H20ClN3O5S
    Degré de pureté :99.76%
    Couleur et forme :Soild
    Masse moléculaire :437.9
  • USP15-IN-1

    CAS :
    <p>USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).</p>
    Formule :C22H23N3O3
    Degré de pureté :99.509% - 99.81%
    Couleur et forme :Solid
    Masse moléculaire :377.44