Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
794 produits trouvés pour "Synthèse ADN/ARN"
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Xanthosine-5'-Triphosphate
CAS :<p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>Formule :C10H15N4O15P3Couleur et forme :SolidMasse moléculaire :524.1645'-O-TBDMS-Bz-dA
CAS :5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.Formule :C23H31N5O4SiCouleur et forme :SolidMasse moléculaire :469.617CSN5-IN-2
CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.Couleur et forme :Odour Solid5'-O-TBDMS-dA
CAS :<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C16H27N5O3SiCouleur et forme :SolidMasse moléculaire :365.50913-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formule :C21H25FN4O2Couleur et forme :SolidMasse moléculaire :384.45Thailanstatin C
CAS :Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.Formule :C30H46ClNO9Couleur et forme :SolidMasse moléculaire :600.15Ac-rC Phosphoramidite
CAS :Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.Formule :C47H64N5O9PSiDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :902.1c-Fos-IN-1
<p>c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.</p>Formule :C28H35NO3Couleur et forme :SolidMasse moléculaire :433.5825'-O-DMT-2'-O-TBDMS-Ac-rC
CAS :5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Formule :C38H47N3O8SiCouleur et forme :SolidMasse moléculaire :701.892Garenoxacin
CAS :<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Formule :C23H20F2N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.41Mulnitorsen
CAS :Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].Formule :C172H217N74O82P17S17Couleur et forme :SolidMasse moléculaire :5704.66HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.495-Methylcytidine 5′-triphosphate trisodium
<p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>Formule :C10H15N3Na3O14P3Couleur et forme :SolidMasse moléculaire :563.135'-O-TBDMS-dG
CAS :5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.Formule :C16H27N5O4SiCouleur et forme :SolidMasse moléculaire :381.50Nusinersen
CAS :Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.Degré de pureté :98.62%Couleur et forme :Solid5-Iminodaunorubicin
CAS :5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Formule :C27H30N2O9Couleur et forme :SolidMasse moléculaire :526.54Carboxy-pyridostatin
CAS :<p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>Formule :C35H34N10O7Couleur et forme :SolidMasse moléculaire :706.71ML-60218
CAS :<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Formule :C19H15Cl2N3O2S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :452.38(+)-Glaucarubinone
(+)-Glaucarubinone is a natural product that can be used as a reference standard.Formule :C25H34O10Couleur et forme :SolidMasse moléculaire :494.537
