Protéase du VIH
Les inhibiteurs de la protéase du VIH sont une classe de médicaments antirétroviraux qui ciblent spécifiquement l'enzyme protéase du virus de l'immunodéficience humaine (VIH). En inhibant cette enzyme, ces composés empêchent le virus de transformer ses polyprotéines en protéines matures et fonctionnelles, bloquant ainsi la production de nouveaux virions infectieux. Les inhibiteurs de la protéase du VIH constituent une pierre angulaire de la thérapie antirétrovirale hautement active (HAART) utilisée pour gérer le VIH/SIDA. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la protéase du VIH pour soutenir votre recherche sur le traitement du VIH, la résistance médicamenteuse et la virologie.
487 produits trouvés pour "Protéase du VIH".
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ELDKWA
CAS :ELDKWA, a highly conserved sequence of amino acids located on the ecto-domain of gp41, serves as the epitope for mAb 2F5, a neutralizing monoclonal antibodyFormule :C35H52N8O11Couleur et forme :SolidMasse moléculaire :760.83SPD-756
CAS :SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formule :C12H16N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.29Indoline
CAS :Indoline ,with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Indoline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C8H9NCouleur et forme :Clear To Yellow LiquidMasse moléculaire :119.16NNRT-IN-11
NNRT-IN-11 (14l) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor, exhibiting EC50 values ranging from 6.50 to 52.9 nM against both wild-type (WT) and a range of HIV-1 mutant strains. NNRT-IN-11 demonstrates antiviral properties.Couleur et forme :Odour SolidHIV-IN-12
HIV-IN-12 (Compound A1) is a dual inhibitor targeting both HIV-1 Vif and reverse transcriptase (RT). It shows potential for use in HIV infection research.Cys-TAT(47-57)
CAS :Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Formule :C67H124N34O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1661.99F9170 TFA
F9170, an antiviral peptide derived from the HIV-1 envelope glycoprotein (amino acids 789-803), targets the LLP1 domain in the virus's envelope proteinFormule :C100H135N21O22·XCF3COOHMasse moléculaire :1983.30IC-1k
IC-1k is an effective inhibitor of HIV-1, exhibiting anti-viral activity with EC50 values of 2.69 nM against HIV-1IIIB and 97.97 nM against HIV-2 ROD. Additionally, IC-1k has been noted to possess cytotoxic properties.Formule :C27H22F2N4O3SCouleur et forme :SolidMasse moléculaire :520.55HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Formule :C42H36ClF10N7O5S2Couleur et forme :SolidMasse moléculaire :1008.35HIV-1 inhibitor-74
HIV-1inhibitor-74 (compound 10c) is a potent inhibitor of HIV-1, displaying an EC50 of 0.0047 µM against HIV-1IIIB. It exhibits cytotoxic properties and effectively inhibits the activity of WTHIV-1RT with an IC50 of 0.134 µM. Additionally, HIV-1inhibitor-74 demonstrates broad-spectrum anti-HIV-1 activity.Formule :C28H31N9O2SCouleur et forme :SolidMasse moléculaire :557.67NF279
CAS :P2X1 antagonistFormule :C49H36N6Na6O23S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1407.17MPG, HIV related
CAS :MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formule :C126H201N35O33SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2766.22NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formule :C32H31N9O3SCouleur et forme :SolidMasse moléculaire :621.71HIV-1 inhibitor-79
HIV-1inhibitor-79 (Compound 3k) is an HIV inhibitor that demonstrates significant inhibitory activity against HIV-1 and its common mutants, with IC50 values of 1.9 nM for HIV-1, K103, 8.7 nM for L100I, and 11 nM for E138K. It exhibits low cytotoxicity and a high selectivity index (CC50 = 21.95 μM, SI = 11478). Additionally, HIV-1inhibitor-79 shows antiviral activity against HIV-2, with an EC50 value of 6.14 μM, and effectively inhibits HIV-1 reverse transcriptase with an IC50 of 25 nM.Formule :C21H17N7OMasse moléculaire :383.41HIV p17 Gag (77-85)
CAS :Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Formule :C44H72N10O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.1HIV-1-IN-83
HIV-1-IN-83 (Compound 18E) is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It demonstrates an IC50 of 0.45 μM against wild-type HIV-1 reverse transcriptase. HIV-1-IN-83 exhibits potent antiviral activity against both wild-type and mutant HIV-1 strains and enhances drug resistance in Y188L and RES056 mutants. The compound is non-toxic up to a concentration of 11.088 μM.Couleur et forme :Odour SolidHIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Couleur et forme :Odour SolidGRL-07524
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.Couleur et forme :Odour SolidBictegravir Sodium
CAS :Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formule :C21H17F3N3NaO5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :471.36HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormule :C26H24N6O2Couleur et forme :SolidMasse moléculaire :452.51
