gsk-3
Les inhibiteurs de la GSK-3 sont des composés qui ciblent la Glycogène Synthase Kinase 3 (GSK-3), une enzyme impliquée dans de nombreux processus cellulaires, y compris le métabolisme du glycogène, la transcription génique et la prolifération cellulaire. La GSK-3 est impliquée dans diverses maladies, telles que le diabète, les troubles neurodégénératifs et le cancer. Les inhibiteurs de la GSK-3 sont des outils importants pour explorer ces voies et développer des thérapies potentielles. Chez CymitQuimica, nous fournissons des inhibiteurs de la GSK-3 pour soutenir vos recherches sur les maladies métaboliques, la neurobiologie et l'oncologie.
107 produits trouvés pour "gsk-3".
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9-ING-41
CAS :9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formule :C22H13FN2O5Degré de pureté :99.28% - 99.32%Couleur et forme :SolidMasse moléculaire :404.35Ref: TM-T14066
1mg50,00€2mg66,00€5mg94,00€1mL*10mM (DMSO)110,00€10mg155,00€25mg309,00€50mg447,00€100mg667,00€Cromolyn sodium
CAS :Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formule :C23H14Na2O11Degré de pureté :99.4% - 99.95%Couleur et forme :White SolidMasse moléculaire :512.33Indazole
CAS :Indazole, a heterocyclic compound, offers diverse biological activities.Formule :C7H6N2Degré de pureté :99.59% - 99.85%Couleur et forme :White SolidMasse moléculaire :118.14BRD0705
CAS :BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.Formule :C20H23N3ODegré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :321.42GSK-3β inhibitor 1
CAS :GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.Formule :C14H10N2ODegré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :222.24Ref: TM-T11467
1mg60,00€5mg130,00€1mL*10mM (DMSO)142,00€10mg200,00€25mg356,00€50mg537,00€100mg737,00€200mg973,00€PROTAC GSK-3β Degrader-1
PROTACGSK-3β Degrader-1 (compound 1) is a degrader targeting GSK-3β with an IC50 of 833 nM. This compound consists of SB-216763 (a GSK-3β inhibitor), a PEG linker, and CRBN (E3 ligase ligand). It reduces neurotoxicity induced by Aβ25-35 peptide and CuSO4 and is applicable in Alzheimer's disease research.Formule :C43H42Cl2N6O9Couleur et forme :SolidMasse moléculaire :856.23903GSK3-IN-1
CAS :GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.Formule :C14H10ClN3OSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :303.77Ref: TM-T9987
2mg42,00€5mg60,00€1mL*10mM (DMSO)73,00€10mg100,00€25mg215,00€50mg318,00€100mg455,00€200mg617,00€GSK3β Inhibitor XI
CAS :GSK3β Inhibitor XI has GSK3β inhibitory effect.Formule :C18H15N5O3Couleur et forme :SolidMasse moléculaire :349.35Phospho-Glycogen Synthase Peptide-2(substrate)
CAS :Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.Formule :C123H191N40O48PCouleur et forme :SolidMasse moléculaire :3029.087BMP agonist 1
BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.Formule :C21H16N2O6Couleur et forme :SolidMasse moléculaire :392.36CHIR-98023
CAS :CHIR-98023 is a bio-active chemical.Formule :C20H16Cl2N8O2Couleur et forme :SolidMasse moléculaire :471.30Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Couleur et forme :Odour SolidRef: TM-L1600
1mgÀ demander10μL*10mM (DMSO)À demander20μL*10mM (DMSO)À demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderGSK3β/mTOR modulator 1
GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.Formule :C19H28O5Couleur et forme :SolidMasse moléculaire :336.19367FRATide
CAS :FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.Formule :C55H102N2O2Couleur et forme :SolidMasse moléculaire :823.433GSK-3β inhibitor 21
GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.Couleur et forme :Odour SolidGSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formule :C15H12N4O2SCouleur et forme :SolidMasse moléculaire :312.35MeBIO
CAS :MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formule :C17H12BrN3O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :370.2Ref: TM-T21966
1mg37,00€5mg71,00€1mL*10mM (DMSO)81,00€10mg111,00€25mg208,00€50mg335,00€100mg492,00€500mg1.071,00€2B-(SP)
CAS :Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)Formule :C71H123N26O29PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1835.87GSK-3 Inhibitor 5
CAS :4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.Formule :C9H6BrNODegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :224.054GSK-3β inhibitor 24
GSK-3β inhibitor24 (Compound 41) is a potent GSK-3β inhibitor with an IC50 of 0.22 nM. It increases GSK-3β phosphorylation at the Ser9 site in a dose-dependent manner and inhibits tau protein hyperphosphorylation by reducing the abundance of p-tau-Ser396. The compound upregulates β-catenin and neurogenesis-related markers (GAP43 and MAP-2), demonstrating significant anti-Alzheimer's disease (AD) activity.Formule :C26H18N4O3Couleur et forme :SolidMasse moléculaire :434.446
