mTOR
Les inhibiteurs de mTOR sont des composés qui inhibent l'activité de la Cible de la Rapamycine chez les Mammifères (mTOR), un régulateur central de la croissance cellulaire, de la prolifération, du métabolisme et de la survie. La voie mTOR est fréquemment altérée dans le cancer et d'autres maladies, ce qui en fait une cible critique pour l'intervention thérapeutique. Les inhibiteurs de mTOR sont largement utilisés dans la recherche liée au cancer, au vieillissement et aux troubles métaboliques. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de mTOR pour soutenir vos recherches en transduction de signaux, oncologie et développement thérapeutique.
162 produits trouvés pour "mTOR"
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ICSN3250 HCl
CAS :<p>ICSN3250 HCl is an mTOR inhibitor that specifically targets cancer cells, preventing mTOR activation and leading to cytotoxicity.</p>Formule :C31H41ClN4O8Degré de pureté :98.46% - 99.60%Couleur et forme :SoildMasse moléculaire :633.13Thioridazine hydrochloride
CAS :Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formule :C21H27ClN2S2Degré de pureté :99.55% - 99.957%Couleur et forme :White To Off-White SolidMasse moléculaire :407.04Rapamycin
CAS :<p>Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.</p>Formule :C51H79NO13Degré de pureté :97.08% - 99.80%Couleur et forme :Yellow SolidMasse moléculaire :914.17MT 63-78
CAS :<p>MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).</p>Formule :C21H14N2O2Degré de pureté :97.11%Couleur et forme :SolidMasse moléculaire :326.35NV-5138
CAS :NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and quality-assured.Formule :C7H13F2NO2Degré de pureté :98% - ≥98%Couleur et forme :SolidMasse moléculaire :181.18NSC781406
CAS :<p>NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).</p>Formule :C29H27F2N5O5S2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :627.68SN32976
CAS :SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential activity for PI3Kα and sparing of PI3Kδ.Formule :C24H33F2N9O4SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :581.64DA-143
DA-143 is a selective inhibitor of DNA-PKcs (IC50: 2.5 nM), demonstrating disparate inhibitory effects on mTOR, PI3KΔ, and ATM, with IC50 values of 280 nM, 106 nM, and 6,594 nM, respectively. This compound effectively blocks the phosphorylation of DNA-PKcs substrates and enhances the sensitivity of cancer cells to doxorubicin.Couleur et forme :Odour SolidDEPTOR-IN-1
CAS :DEPTOR-IN-1 is an inhibitor of DEPTOR with a Kd of 9.3 μM.Formule :C24H16Cl2FNO4Degré de pureté :97.84%Couleur et forme :SolidMasse moléculaire :472.29PI3K-IN-22
CAS :<p>PI3K-IN-22 is a dual kinase inhibitor of PI3Kα and mTOR, with IC50s of 0.9 and 0.6 nM respectively. PI3K-IN-22 could be used in cancer.</p>Formule :C31H35F3N8O3Couleur et forme :SolidMasse moléculaire :624.66RMC-4529
CAS :RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1-(T37/46) in mTOR kinase cellular assays.Formule :C90H139N13O23Couleur et forme :SolidMasse moléculaire :1771.17mTOR inhibitor WYE-28
CAS :Compound 28 (mTOR inhibitor WYE-28) is a selective inhibitor of mTOR (IC50=0.08 nM). Also inhibits PI3Kα (IC50 6 nM).Formule :C30H34N8O5Couleur et forme :SolidMasse moléculaire :586.653mTOR inhibitor-12
mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to centralFormule :C19H24N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.5PF-06465603
CAS :PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.Formule :C22H25N5O5Couleur et forme :SolidMasse moléculaire :439.46mTOR inhibitor 13
CAS :Urea derivative; selective mTOR blocker; IC50: 0.29nM (mTOR), 119nM (PI3Kα).Formule :C24H22N6O2SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :458.54RMC-6272
CAS :RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.Formule :C95H141FN6O27SCouleur et forme :SolidMasse moléculaire :1850.25mTOR inhibitor-14
<p>mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1</p>Degré de pureté :98%Couleur et forme :Odour Solid2DII
2DII is a potent and selective mTORC2 inhibitor. It specifically binds to the mSin1 PH domain, resulting in a decreased phosphorylation of AKT1.Formule :C54H76ClN7O11SCouleur et forme :SolidMasse moléculaire :1066.74AJ2-30
CAS :AJ2-30: Inhibits SLCl5A4, TLR9-B cell activation, MDP transport, NOD signaling; for inflammation study.Formule :C23H22N4Degré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :354.45(32-Carbonyl)-RMC-5552
CAS :(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values >9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.Formule :C93H134N10O24Couleur et forme :SolidMasse moléculaire :1776.141FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Couleur et forme :LiquidmTOR inhibitor 9f
CAS :mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3Kα, respectively.Formule :C25H23N5O2SDegré de pureté :99.18%Couleur et forme :SoildMasse moléculaire :457.55RMC-4627
CAS :RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.Formule :C93H141N11O23Couleur et forme :SolidMasse moléculaire :1781.17WYE-687
CAS :WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).Formule :C28H32N8O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :528.61Thioether-cyclized helix B peptide, CHBP TFA
Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP.Formule :C56H93N19O22S·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1416.52 (free base)Thioether-cyclized helix B peptide, CHBP
CAS :Thioether-cyclized helix B peptide (CHBP) enhances metabolic stability and exerts renoprotective effects by promoting autophagy through the inhibition of mTORFormule :C56H93N19O22SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1416.52PI3K-AKT-mTOR Compound Library
<p>A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with</p>Couleur et forme :Odour SolidYB-3-17
CAS :YB-3-17 is a bifunctional molecule that can inhibit mTOR with an IC50 of 0.22 nM or degrade the G1 to S phase transition 1 gene (GSPT1) through the PROTAC mechanism, with a DC50 of 5 nM. It exhibits antiproliferative activity at nanomolar concentrations in various glioblastoma cell lines. Additionally, YB-3-17 shows antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon)Formule :C38H39N11O6Couleur et forme :SolidMasse moléculaire :745.786MKC-1
CAS :MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.Formule :C22H16N4O4Degré de pureté :99.63% - 99.85%Couleur et forme :SolidMasse moléculaire :400.39Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Couleur et forme :Odour SolidQL-IX-55
CAS :QL-IX-55 has a wide range of applications in life science related research.Formule :C24H14F4N4OCouleur et forme :SolidMasse moléculaire :450.39Aschantin
CAS :<p>Aschantin is a useful organic compound for research related to life sciences. The catalog number is T126072 and the CAS number is 13060-15-6.</p>Formule :C22H24O7Couleur et forme :SolidMasse moléculaire :400.427MCX 28
CAS :MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.Formule :C25H19N5O4S3Couleur et forme :SolidMasse moléculaire :549.64S6K1-IN-DG2
CAS :S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Formule :C16H17BrN6ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :389.25Anti-Phospho-MTOR (Ser2448) Antibody (2K503)
<p>Anti-Phospho-MTOR (Ser2448) Antibody (2K503) is an antibody targeting Phospho-MTOR (Ser2448). Anti-Phospho-MTOR (Ser2448) Antibody (2K503) can be used in ELISA, WB, IHC, IF.</p>Couleur et forme :Odour LiquidCbz-B3A
CAS :Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.Formule :C35H58N6O9Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :706.87Anti-Phospho-mTOR (Ser2481) Antibody (4R8)
Anti-Phospho-MTOR (Ser2481) Antibody (4R8) is an antibody targeting Phospho-MTOR (Ser2481). Anti-Phospho-MTOR (Ser2481) Antibody (4R8) can be used in ELISA, WB, IF.Couleur et forme :Odour LiquidRMC-5552
CAS :RMC-5552 selectively inhibits mTORC1 with ~40-fold selectivity over mTORC2, demonstrating anticancer activity and research utility.Formule :C93H136N10O24Couleur et forme :SolidMasse moléculaire :1778.16Temsirolimus
CAS :Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formule :C56H87NO16Degré de pureté :97.76% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :1030.29Torin 2
CAS :Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.Formule :C24H15F3N4ODegré de pureté :98.31% - 99.32%Couleur et forme :SolidMasse moléculaire :432.4Lupiwighteone
CAS :Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formule :C20H18O5Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :338.35PI-103
CAS :<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Formule :C19H16N4O3Degré de pureté :97.79% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36WYE-354
CAS :WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formule :C24H29N7O5Degré de pureté :97.86% - 99.61%Couleur et forme :SolidMasse moléculaire :495.53Bimiralisib
CAS :Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Formule :C17H20F3N7O2Degré de pureté :97.58% - 98.92%Couleur et forme :SolidMasse moléculaire :411.38Omipalisib
CAS :<p>Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.</p>Formule :C25H17F2N5O3SDegré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :505.5BGT226
CAS :BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formule :C28H25F3N6O2Degré de pureté :95.74% - 99.78%Couleur et forme :SolidMasse moléculaire :534.53XL388
CAS :XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.Formule :C23H22FN3O4SDegré de pureté :99.39% - 99.53%Couleur et forme :SolidMasse moléculaire :455.5GNE-493
CAS :GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM forFormule :C17H20N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :372.44Cyclovirobuxine D
CAS :Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formule :C26H46N2ODegré de pureté :97.78% - 98%Couleur et forme :SolidMasse moléculaire :402.66OSI-027
CAS :OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formule :C21H22N6O3Degré de pureté :97.42%Couleur et forme :SolidMasse moléculaire :406.44PF-04691502
CAS :<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Formule :C22H27N5O4Degré de pureté :96.27% - ≥95%Couleur et forme :SolidMasse moléculaire :425.48Samotolisib
CAS :<p>Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.</p>Formule :C23H26N4O3Degré de pureté :98.41% - 99.69%Couleur et forme :SolidMasse moléculaire :406.48D-α-Hydroxyglutaric acid disodium
CAS :D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.Formule :C5H6Na2O5Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :192.083BDO
CAS :3BDO is a new mTOR activator. 3BDO inhibits autophagy.Formule :C18H17NO5Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :327.33Autogramin-1
CAS :<p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>Formule :C23H27N5O5SDegré de pureté :97.69% - 99.25%Couleur et forme :SolidMasse moléculaire :485.56GNE-477
CAS :<p>GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.</p>Formule :C21H28N8O3S2Degré de pureté :98.88% - 99.55%Couleur et forme :SolidMasse moléculaire :504.63Salidroside
CAS :Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Formule :C14H20O7Degré de pureté :97.81%Couleur et forme :Red-Brown Fine PowderMasse moléculaire :300.30Corynoxine
CAS :<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Formule :C22H28N2O4Degré de pureté :96.83% - 99.93%Couleur et forme :SolidMasse moléculaire :384.47Mito-LND
CAS :Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formule :C43H45BrCl2N3OPDegré de pureté :97.25% - 98.34%Couleur et forme :SolidMasse moléculaire :801.62GNE-317
CAS :GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).Formule :C19H22N6O3SDegré de pureté :98.42% - 99.54%Couleur et forme :SolidMasse moléculaire :414.48Everolimus
CAS :<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Formule :C53H83NO14Degré de pureté :97.76% - 99.78%Couleur et forme :Off-White To Light Yellow PowdMasse moléculaire :958.2225(R,S)-Ruscogenin
CAS :<p>25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular carcinoma.</p>Formule :C27H42O4Degré de pureté :99.32% - 99.89%Couleur et forme :SolidMasse moléculaire :430.62AZD-8055
CAS :<p>AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.</p>Formule :C25H31N5O4Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :465.54NV-5138 hydrochloride
NV-5138 hydrochloride: a leucine analog, oral brain mTORC1 activator via Sestrin2, for antidepressant research.Formule :C7H14ClF2NO2Couleur et forme :SolidMasse moléculaire :217.64Palomid 529
CAS :Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formule :C24H22O6Degré de pureté :98.40% - 98.59%Couleur et forme :SolidMasse moléculaire :406.43KU-0063794
CAS :KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.Formule :C25H31N5O4Degré de pureté :98.21% - >99.99%Couleur et forme :SolidMasse moléculaire :465.54WYE-687 dihydrochloride
CAS :WYE-687 dihydrochloride is an mTOR inhibitor with IC50 of 7 nM, also targeting PI3Kα (81 nM) and PI3Kγ (3.11 μM).Formule :C28H34Cl2N8O3Couleur et forme :SolidMasse moléculaire :601.53SC99
CAS :SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formule :C15H8Cl2FN3ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :336.15L-Leucine
CAS :L-Leucine is an essential amino acid vital for protein synthesis, metabolism, muscle and bone repair, blood sugar control, and wound healing.Formule :C6H13NO2Degré de pureté :99.83%Couleur et forme :White Solid CrystallineMasse moléculaire :131.17Vistusertib
CAS :Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formule :C25H30N6O3Degré de pureté :97.08% - 99.06%Couleur et forme :SolidMasse moléculaire :462.54Onatasertib
CAS :Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formule :C21H27N5O3Degré de pureté :99.14% - 99.93%Couleur et forme :SolidMasse moléculaire :397.47Voxtalisib
CAS :Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.Formule :C13H14N6ODegré de pureté :98.21% - 99.69%Couleur et forme :SolidMasse moléculaire :270.29PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.36Polyphyllin I
CAS :<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Formule :C44H70O16Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :855.02Torin 1
CAS :<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Formule :C35H28F3N5O2Degré de pureté :98.3% - 99.33%Couleur et forme :SolidMasse moléculaire :607.62G5-7
CAS :G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39Apitolisib
CAS :Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).Formule :C23H30N8O3SDegré de pureté :98.28% - 99.64%Couleur et forme :SolidMasse moléculaire :498.6Daphnetin
CAS :<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14GSK1059615
CAS :GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Formule :C18H11N3O2SDegré de pureté :99.3% - ≥95%Couleur et forme :SolidMasse moléculaire :333.36Serabelisib
CAS :Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).Formule :C19H17N5O3Degré de pureté :98.41% - 99.5%Couleur et forme :SolidMasse moléculaire :363.37LY 303511 hydrochloride
CAS :LY 303511 hydrochloride is a potent mTOR inhibitorFormule :C19H19ClN2O2Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :342.82Sapanisertib
CAS :<p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>Formule :C15H15N7ODegré de pureté :99.19% - >99.99%Couleur et forme :SolidMasse moléculaire :309.33LY-2584702 free base
CAS :LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).Formule :C21H19F4N7Degré de pureté :98.72% - 99.51%Couleur et forme :SolidMasse moléculaire :445.42Hederacolchiside A1
CAS :Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formule :C47H76O16Degré de pureté :98.76% - 99.92%Couleur et forme :SolidMasse moléculaire :897.1Arnicolide D
CAS :Arnicolide D is a sesquiterpene lactone.Formule :C19H24O5Degré de pureté :96.66% - 99.93%Couleur et forme :SolidMasse moléculaire :332.39CDC25B-IN-2
CAS :BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.Formule :C15H12N2O3Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :268.27CH5132799
CAS :CH5132799 has been used in trials studying the treatment of Solid Tumors.Formule :C15H19N7O3SDegré de pureté :99.41% - 99.87%Couleur et forme :SolidMasse moléculaire :377.42GSK-25
CAS :GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Formule :C24H16Cl2F2N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :513.33Torkinib
CAS :Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).Formule :C16H16N6ODegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :308.34mTOR inhibitor-1
CAS :C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formule :C16H15BrN2O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :363.21Rotundic acid
CAS :Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Formule :C30H48O5Degré de pureté :96.91% - 99.97%Couleur et forme :SolidMasse moléculaire :488.70TMBIM6 antagonist-1
CAS :<p>TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor</p>Formule :C15H12N2O3Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :268.27Zotarolimus
CAS :Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).Formule :C52H79N5O12Degré de pureté :95% - 98.01%Couleur et forme :SolidMasse moléculaire :966.21(+)-Usnic acid
CAS :(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.Formule :C18H16O7Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :344.32CZ415
CAS :<p>CZ415 is a potent and highly selective mTOR inhibitor.</p>Formule :C22H29N5O4SDegré de pureté :97.54% - 98.36%Couleur et forme :SolidMasse moléculaire :459.56VS-5584
CAS :<p>VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.</p>Formule :C17H22N8ODegré de pureté :97.82% - 99.54%Couleur et forme :SolidMasse moléculaire :354.41Dihydromyricetin
CAS :<p>Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.</p>Formule :C15H12O8Degré de pureté :96.68% - 98.229%Couleur et forme :SolidMasse moléculaire :320.25MHY1485
CAS :MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.Formule :C17H21N7O4Degré de pureté :97.74% - >99.99%Couleur et forme :SolidMasse moléculaire :387.39ETP-45658
CAS :ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).Formule :C16H17N5O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :311.34
