Oligosaccharides

<p>4-Methoxyphenyl 2-acetamido-3,6-di-O-acetyl-4-O-[2,4-di-O-(3,6,9)-triacetyldi-O-(3,4,6)-triacetyldiacetamido]-bDglucopyranoside (MPPA) is a modification of the natural oligosaccharide 3,6,-di-O-(2,4-di-O-(3,6,9)-triacetyldiacyl)-bDmannopyranosyl. MPPA is synthesized by methylation and glycosylation of glucose residues in the backbone of the natural oligosaccharide. The methylated glycosidic linkages are substituted for acetamido groups in order to confer water solubility to the molecule. MPPA has been shown to be an effective inhibitor of influenza virus replication in vitro.</p>

<p>Chitoheptaose 7HCl is a synthetic, complex carbohydrate with a CAS number of 68232-35-9. This product is custom synthesized to order and can be modified according to your specifications. It is available in high purity.</p>

<p>4-Methoxyphenyl 4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a carbohydrate with the CAS number 150412-80-9. It is an Oligosaccharide that is synthesized from monosaccharides and saccharides. This product can be custom synthesized to produce high purity, methylated, glycosylated and fluorinated products. There are many modifications that can be made to this carbohydrate using Click chemistry.</p>

<p>Fucosyloligosaccharide present in human milk and colostrum</p>

<p>Methyl 6-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a carbohydrate that has been modified with fluorination. It is synthesized by the methylation of glucose and mannose residues, followed by glycosylation. Methyl 6-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a custom synthesis and can be ordered in high purity.</p>

<p>3'-Sialyl Lewis A-PAA-biotin is a carbohydrate that is used as a research tool for investigating the structure and function of glycoproteins, glycolipids, and glycosaminoglycans. It contains 3'-sialic acid linked to the terminal β-D-galactopyranosyl residue of a poly(amino acid) backbone. This product has been synthesized by custom synthesis and contains high purity with a custom synthesis.</p>

<p>Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. It also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods and may be used as an ingredient in culture media.</p>

<p>An antioxidant chelator used in skin care. Also used in organ transplantation preservation solutions, due to its ability to inhibit hydroxyl radical production, via the complexation of oxidation-promoting iron found in blood.</p>

<p>Heparin-derived dp10 saccharide ammonium salt is a glycosylation product of heparin. This compound is synthesized by the treatment of heparin with a fluorinating agent, such as N-fluoro-N'-(2-chloroethyl)peroxycarbonyl chloride or N-fluoro-N'-(2-bromoethyl)peroxycarbonyl chloride, followed by reaction with an amine. The compound can be modified for specific applications through the use of click chemistry, which allows for the selective modification of either the sugar or side chain of the molecule. This product has been characterized and shown to have high purity and a CAS number.</p>

<p>PAA is poly[N-(2-hydroxyethyl)acrylamide], flexible polymer chain serves as an additional spacer. Mr approx. 30 kDa (according to gel-filtration, proteins as Mr markers). Carbohydrate content is 20% mol.</p>

<p>The glycosylation process is a chemical reaction in which an organic molecule is attached to a sugar or other carbohydrate. The product of this process is known as a glycoside. Glycosylations are important in the synthesis of complex carbohydrates and glycoconjugates. The most common glycosidic bond that is formed is between the hydroxyl group of a saccharide (such as glucose) and the amino group of another saccharide (such as N-acetylglucosamine). The most common type of glycosylation reaction is the formation of an O-glycosidic bond between two sugars, such as glucose and N-acetylgalactosamine, to form the disaccharide lactose. There are many different types of glycosylations, including methylation, Click modification, fluorination, saccharide modification, and custom synthesis.<br>Methylation: Methylation is a chemical reaction where one or more hyd</p>

<p>4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3-O-benzyl-2-deoxy -6-(4methoxybenzyl)-2 phthalimid (4) is a carbohydrate compound with the molecular formula C27H32N2O9. It is a white to off white powder that has a molecular weight of 565.5 and an empirical formula of C27H32N2O9.</p>

<p>Sucrose dodecanoate is a sugar ester that has been shown to be a 5-HT agonist. It is used as an absorption enhancer for the treatment of choroidal neovascularization. Sucrose dodecanoate was also found to have trypsin-like protease activity and cyclic peptide properties. This drug has been shown to increase insulin sensitivity and growth factor levels in animal models, which may be due to its effects on serine proteases. Sucrose dodecanoate is available as a pharmaceutical dosage form containing fatty acid esters at a concentration of 10%. It has a viscosity of approximately 100 cP, which is expected to provide good bioavailability.</p>

<p>Disaccharide; substrate for glucanases and laminaribiose phosphorylase</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-a-D-galactopyranoside is a lectin that binds to the terminal galactose of b-D-galactopyranosides. It has been shown to be a potent inhibitor of cellular death and is able to bind to the surface of cells, preventing their destruction by the immune system or other natural factors. The binding site for MGA is found on cell membranes, and it can also act as an antiinflammatory agent. MGA has also been shown to inhibit interactions between proteins, which may lead to changes in protein synthesis and regulation. Lectins are proteins that bind to specific carbohydrates on the surfaces of cells. They are part of a group called glycoproteins and are often used as probes in techniques such as lectin histochemistry and immunohistochemistry.</p>

<p>4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-4-O-levulinoyl-2-phthalimido-b-D-[1]glucopyranosyl)-3,6,6'-triphosphate (4MP) is a fluorinated monosaccharide that can be synthesized from 4,4'-dimethoxybenzophenone and 2,3,4,5',6'-pentachlorobenzene. This synthetic compound is used to prepare modified polysaccharides. 4MP has been shown to methylate glycoproteins and modify oligosaccharides. It has also been shown to inhibit the growth of Mycobacterium tuberculosis by inhibiting the synthesis of cell wall lipids.</p>

<p>Disaccharide is a carbohydrate with two simple sugars. It is soluble in water and has a density of 1.621 g/ml. Disaccharides are found in the tissues of many plants and animals, where they can be hydrolyzed by various enzymes to release monosaccharides. Disaccharides are also found in certain types of lichen and algae, where they are produced through photosynthesis. The most common disaccharides are sucrose, lactose, maltose, trehalose, and cellobiose. The simplest type of disaccharide is called a monosaccharide or sugar molecule. Monosaccarides have the same chemical formula but different physical forms that depend on their molecular mass (i.e., they may be a solid or liquid). Disaccharides can be classified as either sulfuric or organic solvent-soluble depending on whether they dissolve in sulfuric acid or an organic solvent such as ethanol or</p>

<p>2'-Fucosyllactose peracetate is a synthetic, oligosaccharide-type complex carbohydrate. It is custom synthesized and modified with fluorination, methylation, and click chemistry. 2'-Fucosyllactose peracetate is used as a glycosylation reagent in the synthesis of polysaccharides. The CAS number for this product is 6569-81-8. This product has been shown to be highly purified (&gt; 99%) and have an excellent shelf life (up to two years).</p>

<p>2-O-(β-D-galactopyranosyl)-D-glucose is a sugar that can be custom synthesized to meet your needs. It is an oligosaccharide, polysaccharide, and carbohydrate that has been modified with methylation, glycosylation, and carbonylation. This product is available in high purity and fluorination.</p>

<p>Blood group antigen with spacer arm</p>

<p>Intermediate degradation product of lyso-GM3</p>

<p>Synthetic building block for oligosaccharide synthesis</p>

<p>D-Cellotriose undecaacetate is a glycosylation product of cellobiose and erythritol. It is a methylated polysaccharide, which is an oligosaccharide that contains a single sugar unit. This compound can be custom synthesized and has high purity. D-Cellotriose undecaacetate is used in the synthesis of polysaccharides in the food industry and for medical purposes as a drug delivery system.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose, with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarobiose is reported to exhibit skin moisturising and whitening properties.</p>

<p>Raffinose is the most abundant of the family of oligosaccharides that are alpha-galactosyl derivatives of sucrose (Collins, 2006). The other main member of the group is the tetrasaccharide stachyose. Raffinose is found in sugar beet molasses and whole grains. Soybean oligosaccharides make up approximately 5% of dry matter in whole beans and up to 8% of dry matter in soybean meal. Together raffinose and stachyose rank second only to sucrose in abundance, as water-soluble carbohydrates (Kumar, 2010).</p>

<p>2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-a-D-galactopyranosyl-1-O-[4-(aminomethyl)benzoyl]-L-serine (2ADOGB) is a side chain of the amino acid L -serine. It has been shown to have antihypertensive, vasodilatory, and diuretic properties in mice. 2ADOGB is converted to an erythroimidazole derivative by aminomethylation and then binds to DNA as a tautomer. This binding inhibits transcription of genes that encode enzymes responsible for synthesizing prostaglandins, thereby reducing inflammation and pain.</p>

<p>3,4-Di-O-acetyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D mannopyranose is a modification of the carbohydrate oligosaccharide. It is a custom synthesis that has high purity and CAS number. The structure of the molecule is an Oligosaccharide with a Carbohydrate. This molecule is an example of a complex carbohydrate. The monosaccharide in this compound is glucose and it has been methylated and glycosylated. This molecule also has a polysaccharide sugar which can be fluorinated or saccharided.</p>

<p>Heparin disaccharide III-S trisodium salt is a synthetic and custom-synthesized drug with high purity. It is a complex carbohydrate with a molecular weight of 597.1 g/mol, an Oligosaccharide with a molecular weight of 1,008.3 g/mol, and a Glycosylation with a molecular weight of 1,069.4 g/mol. Heparin disaccharide III-S trisodium salt has been modified by the addition of fluorine atoms to create an active form that is highly reactive to electrophilic groups on proteins or nucleic acids. It can be used for Click modification or methylation reactions to modify proteins or DNA molecules in order to study protein-protein interactions or protein conformational changes in response to external stimuli.</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-6-sulfo-b-D-glucopyranose is a glycosaminoglycan that can be used as an immunomodulator. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in experimental cancer tissues and to stimulate the activity of lymphocytes, which may be due to its ability to regulate camp levels. 2A2D4OSBG also has regulatory effects on monoclonal antibodies and inhibits the immune reaction caused by autoimmune diseases.</p>

<p>Sucrose is a sugar that is used as a food additive. It is the disaccharide of glucose and fructose, which are two monosaccharides. Sucrose can be synthesized by the glycosylation of glucose and fructose in an α-1,2 linkage. Sucrose can also be synthesized by the fluorination of sucrose followed by methylation with methylamine. The synthesis of sucrose starts with the reaction of acrylonitrile with formaldehyde to produce acrylonitrile trimer, which is then reacted with methanol to produce methyl 3-hydroxybutyrate. This product undergoes a series of reactions to form sucrose.</p>

<p>This compound is a custom synthesis. It is an oligosaccharide, polysaccharide and modification of saccharides. The compound has been modified with methylation, glycosylation, and fluorination. This compound is a high purity product with the CAS number 93496-44-7.</p>

<p>Isolated from ivory-nut mannan hydrolysates</p>

<p>4-Methoxyphenyl 4-O-(4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,4,6-(1',4'-dioxan)-tris(2,3,5',6'-tetraethoxy)phenol</p>

<p>Benzyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-a-D-glucopyranoside is a synthetic substrate that is used in the synthesis of disaccharides. It is catalytic and has an efficient method for the preparation of acetonitrile, which can be eluted with acetic acid. It is a reagent that reacts with halides to form equimolar acetates. Acetylated benzyl 2-acetamido-2 deoxy 3 O-(b D galactopyranosyl) a D glucopyranoside can be obtained by reacting benzyl 2 acetamido 2 deoxy 3 O-(b D galactopyranosyl) a D glucopyranoside with acetic anhydride.</p>

<p>Lactobionic acid is produced by oxidation of lactose. It is widely used in the food and in pharmaceutical field, due to its excellent biocompatibility, biodegradability, nontoxicity, chelating, amphiphilic and antioxidant properties.  Lactobionic acid is produced as a white solid powder, freely soluble in water and slightly soluble in anhydrous ethanol and methanol.</p>

<p>Trehalose-6-phosphate dipotassium salt is a natural sugar that is found in plants, animals, and fungi. It functions as a carbohydrate reserve and protects cells against osmotic stress. Trehalose-6-phosphate dipotassium salt can be synthesized by the enzyme trehalase from the sugar trehalose and 6-phosphate. It has been shown to protect cells from weevil infestation, which may be due to its ability to produce abiotic or biotic stress. Trehalose-6-phosphate dipotassium salt can be purified using hydrophilic interaction chromatography on an on-line system.</p>

<p>This is a synthetic, high purity and custom-synthesized carbohydrate. The chemical name is 1,2,3,6-Tetra-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-b-D-thioglucopyranose. It has been modified with the Click reaction to allow for chemical modification. This product is a complex carbohydrate that has been fluorinated to create an organic fluorine compound.</p>

<p>Produced by the reverse hydrolysis of a mannose substrate.  Isolated from the partial hydrolysates of bakers' yeast (Saccharomyces cerevisiae) mannan.  This disaccharide also forms the sugar portion of the phospholipid, phosphatidylinositodimannoside, of Mycobacterium tuberculosis.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarohexaose is reported to have potential for novel cosmeceuticals.</p>

<p>N-Glycolylneuraminic acid dimer sodium salt is a synthetic sugar that is a glycosylat of N-glycolylneuraminic acid. It is soluble in water and has a CAS number of 1114-12-3. The product has been modified with methyl groups and is available for custom synthesis. It can be used as an intermediate for the synthesis of oligosaccharides, or it can be modified to form complex carbohydrates. This product has been fluorinated and is high purity, making it ideal for use in Click chemistry applications.</p>

<p>Disialylated tetrasaccharide naturally present in human breast milk that has been identified as one of the binding sites of the C fragment of the clostridial tetanus toxin.</p>

<p>GQ1b ganglioside (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, two sialic acids (NeuAc) linked α2,3/α2,8 to the terminal galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Anti-GQ1b ganglioside antibody is associated with Miller Fisher syndrome and is also found in patients with related conditions that may share the same pathogenic mechanism, such as, Bickerstaff brainstem encephalitis. Thus, the measurement of the anti-GQ1b antibody in suspected cases of Miller Fisher syndrome is a useful diagnostic marker (Paparounas, 2004). It has been found that GQ1b ganglioside contributes to synaptic transmission and synapse formation. Low concentrations of GQ1b ganglioside, evoked dopamine (DA) release from laboratory tissues (Chen, 2018).</p>

<p>Produced from high maltose syrup by treatment with transglucosidase</p>

<p>Sucrose octabenzoate is a practically colorless, odorless, transparent, glass-like material which is compatible with a number of synthetic resins, such as polyvinyl chloride, vinyl chloride-vinyl acetate copolymer, polyvinyl acetate and cellulose acetate. Sucrose octabenzoate improves the hardness and gloss of these products and has also been found to be useful as a component of inks, adhesives, coatings and plastic objects.</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.</p>

<p>Isolated from the partial acid and enzymic hydrolysates of several of the mannans,  galactomannans and glucomannans. While the trisaccharide has been isolated from all of these sources the tetrasaccharide has only been isolated from ivory-nut mannan, white spruce (Picea glauca) and Pinus strobus glucomannans. Crystalline penta- and hexa-saccharides have been isolated from ivory-nut mannan hydrolysates.</p>

<p>The hyaluronic acid discaccharide and other enzymatically produced polymer homologs from hyaluronic acid have been of value in the study of hyaluronic acid metabolism in healthy and diseased tissues (Hascall, 2019). Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. The unsaturated disaccharide hyalobiuronic acid is released from hyaluronic acid by the action of hyaluronidase on umbilical cord (Weissman, 1954).</p>

<p>Sodium Tetragalacturonate (α-1,4 sodium tetrgalacturonate) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>Please enquire for more information about 2-O-(a-D-Galactopyranosyl)-a-L-fucopyranosyl propylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Amino-6-deoxy-D-lactosylamine is a modified sugar that is used to synthesize glycosides. It is also used as a reagent for the methylation of saccharides and polysaccharides. This product can be custom synthesized or ordered from our catalog. We offer high purity 6-amino-6-deoxy-D-lactosylamine, which has been chemically modified with fluorine and has a CAS number of 7092-12-3. It is available in different quantities and can be ordered with other custom modifications, such as Click chemistry.</p>