Ligands organométalliques
Dans cette catégorie, vous trouverez un grand nombre de molécules organométalliques utilisées comme ligands dans les biomolécules. Ces ligands organométalliques peuvent être utilisés en chimie organique et en synthèse au laboratoire. Ils jouent un rôle crucial dans la formation de complexes de coordination et la catalyse de diverses réactions chimiques. Chez CymitQuimica, nous offrons une sélection diversifiée de ligands organométalliques de haute qualité pour soutenir vos recherches et besoins industriels.
Sous-catégories appartenant à la catégorie "Ligands organométalliques"
- Ligands de Buchwald(22 produits)
- DPEN(4 produits)
- DPHEN(4 produits)
- JOSIPHOS(4 produits)
- Phosphine(497 produits)
- Porphyrines(75 produits)
2889 produits trouvés pour "Ligands organométalliques"
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Pimasertib
CAS :A selective inhibitor of MEK1/2 kinase. Anti-proliferative and pro-apoptotic in multiple myeloma (MM) cells via G0/G1 cell cycle arrest and caspase 3 and PARP cleavage, respectively. Synergistic with other anti-MM therapies. Has anti-tumor effects in some solid tumors, such as in K-ras mutated colorectal cancer.Formule :C15H15FIN3O3Degré de pureté :Min. 95%Couleur et forme :White To Yellow SolidMasse moléculaire :431.2 g/molFeprazone
CAS :Anti-inflammatory; inducer of P450 II B familyFormule :C20H20N2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :320.39 g/molA 769662
CAS :Allosteric activator of AMP-activated protein kinase (AMPK) acting on the AMPK-β subunit with therapeutic potential in metabolic disorders such as diabetes, obesity, etc. A769662 also blocks the differentiation of mouse embryonic stem cells (mESCs) and maintains the mESCs in naïve state even in the absence of leukemia inhibitory factor (2i/L).Formule :C20H12N2O3SDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :360.39 g/molGW 833972A
CAS :A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).Formule :C18H13ClF3N5ODegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :407.78 g/molFluvastatin sodium
CAS :Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.
Formule :C24H25FNNaO4Degré de pureté :Min. 98%Couleur et forme :Off-White PowderMasse moléculaire :433.45 g/molFurosemide - Bio-X ™
CAS :Produit contrôléFurosemide is a potent loop diuretic that is used in the treatment of hypertension, liver cirrhosis, renal disease and heart failure. This drug acts on the kidney to increase water loss from the body. It inhibits electrolyte reabsorption. Furosemide also exerts vasodilatory effects.
Formule :C12H11ClN2O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :330.74 g/molTacrolimus - Bio-X ™
CAS :Tacrolimus is a calcineurin inhibitor drug that is used for the prevention of rejection after an organ transplant. This drug can also be used in the treatment of severe atopic dermatitis. Tacrolimus’ mechanism of action is not well known however it is understood that this drug inhibits T-lymphocyte activation by binding to an intracellular protein called FKBP-12. This drug also has anti-inflammatory properties.
Formule :C44H69NO12Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :804.02 g/molLoratadine - Bio-X ™
CAS :Loratadine is a non-sedating, inverse agonist antihistamine used for the treatment of allergic rhinitis, an IgE (immunoglobulin E) mediated disease. Loratadine binds to histamine H1 receptors, preventing histamine from binding and causing an allergic reaction.It has been found to inhibit the release of eosinophil cationic protein by acting on different components of allergic inflammation, in particular in the modulation of ICAM-1 expression on nasal epithelial cells as a mechanism of protective for the epithelium, and therefore, the damage of mucosa is reduced. In recent studies, it was found that loratadine is a potent HR1 antagonist with in vitro inhbitory effect on human mast-cell lines, HMC-1 (from mast cell leukaemia) with an IC50 between 10 and 50 μM.Loratadine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C22H23ClN2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :382.88 g/molMalotilate - Bio-X ™
CAS :Malotilate is a pharmacological agent that is used to treat symptoms of hepatitis, bowel disease, and collagen diseases. This drug reduces collagen synthesis and cell migration activity of fibroblasts in vitro. It also has been shown to facilitate liver regeneration in rats.Formule :C12H16O4S2Degré de pureté :(%) Min. 95%Couleur et forme :PowderMasse moléculaire :288.39 g/molI-RW
The peptide IRW, characterised from egg protein, exhibits inhibitory properties against the angiotensin converting enzyme (ACE2) and could be used to prevent cardiovascular disease with further research. Treatment of hypertensive mice with IRW induced endothelium-dependent vasorelaxation and reduced vascular inflammation. The IRW tripeptide acts as anti-hypertensive by upregulating ACE2 activity via the Mas receptor (MasR) and upregulating Akt/eNOS signalling in the aorta. IRW also induces superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activity. These may play a factor in IRW's role as an anti-inflammatory. IRW shows promise as a nutraceutical for inflammatory conditions and a tool for drug development in cardiovascular disease.Degré de pureté :Min. 95%Masse moléculaire :1,830.9 g/molRamipril - Bio-X ™
CAS :Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. It is used in the treatment of high blood pressure, congestive heart failure and other cardiovascular diseases. Ramipril inhibits the conversion of angiotensin I to angiotensin II by blocking ACE, which lowers blood pressure and reduces fluid retention.This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C23H32N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :416.51 g/molNalmefene hydrochloride
CAS :Produit contrôléOpioid receptor antagonistFormule :C21H25NO3•HClDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :375.89 g/molR-Rolipram
CAS :Inhibitor of PDE4 enzyme; anti-inflammatory
Formule :C16H21NO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :275.34 g/mol(S)-Mephenytoin - Bio-X ™
CAS :(S)-Mephenytoin is a substrate of cytochrome P450 enzyme CYP2C19 (a hydroxylase). It is an effective anticonvulsant that improves control of seizures in patients. According to studies, the drug exhibits a genetic polymorphism in CYP2C19 that results in reduced metabolism in some individuals.Formule :C12H14N2O2Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :218.25 g/molDocetaxel - Bio-X ™
CAS :Docetaxel is an antineoplastic agent that is used to treat various cancers such as breast and prostate cancer. This drug interferes with the normal function of microtubule growth. It is an anti-mitotic drug used in chemotherapy. Research has shown that this drug also induces programmed cell death in cancer cells.Formule :C43H53NO14Degré de pureté :Min. 90 Area-%Couleur et forme :White/Off-White SolidMasse moléculaire :807.88 g/molAcid alpha-glucosidase (83-99), human
Acid α-glucosidase (83-99) (human) is derived from the exogenous enzyme which degrades glycogen, maltose and isomaltose through targeting alpha -1,4 and alpha -1,6 linkages. Once synthesised in its precursor form, within the Golgi it is glycosylated and acquires mannose 6-phosphate residues. This allows it to be transported to the Lysosome in a multistep process.Pompe disease, also known as glycogen storage disease type II, can be diagnosed through the absence of acid α-glucosidase activity within patients. Therefore glycogen degradation in the lysosome is inhibited by this autosomal recessive disorder. This results in the accumulation of glycogen and tissue destruction, hence contributing to the pathologies of muscle weakness and respiratory failure, associated with infantile onset and adult onset Pompe disease.Degré de pureté :Min. 95%Masse moléculaire :1,844.9 g/molAminopterin
CAS :Aminopterin is an antineoplastic agent and antifolate, which is a synthetic derivative of pteroylglutamic acid. It functions as a chemotherapeutic agent by inhibiting dihydrofolate reductase, an enzyme crucial in the folic acid pathway, thereby preventing the conversion of dihydrofolate to tetrahydrofolate. This disruption leads to impaired synthesis of purine nucleotides and thymidylate, which are essential for DNA synthesis and cell division.Formule :C19H20N8O5Degré de pureté :Min. 97 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :440.41 g/molN-Trityl candesartan cilexetil
CAS :Angiotensin II receptor antagonist
Formule :C52H48N6O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :852.97 g/molOxaprozin - Bio-X ™
CAS :Oxaprozin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis and rheumatoid arthritis. This drug relieves swelling and inflammation by inhibiting the enzyme cyclooxygenase which in turn inhibits prostaglandin synthesis.Formule :C18H15NO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :293.32 g/mol
