Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Couleur et forme :LiquidVinzolidine
CAS :<p>Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.</p>Formule :C48H58ClN5O9Couleur et forme :SolidMasse moléculaire :884.462-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Formule :C12H24ClNO4Couleur et forme :SolidMasse moléculaire :281.78TTBK1-IN-2
CAS :<p>TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.</p>Formule :C18H13ClN4ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :336.77αvβ5 integrin-IN-1
CAS :<p>αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.</p>Formule :C25H28F3N3O3Couleur et forme :SolidMasse moléculaire :475.512AB-3PRGD2
CAS :<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formule :C137H215IN30O45SCouleur et forme :SolidMasse moléculaire :3161.32PDK-IN-1
CAS :<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29Anti-α-Tubulin Antibody, AF555 conjugate
<p>Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the</p>Couleur et forme :SolidFuzapladib
CAS :<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Formule :C15H20F3N3O3SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :379.4MPH-220
CAS :<p>MPH-220: Oral myosin-2 inhibitor, induces muscle relaxation, useful for spasticity research.</p>Formule :C20H21N3O3SCouleur et forme :SolidMasse moléculaire :383.46Lys-Gln-Ala-Gly-Asp-Val
CAS :<p>KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.</p>Formule :C25H44N8O10Couleur et forme :SolidMasse moléculaire :616.66KT D606
CAS :<p>KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.</p>Formule :C59H50N6O10Couleur et forme :SolidMasse moléculaire :1003.06Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formule :C25H41N11O8SCouleur et forme :SolidMasse moléculaire :655.727T-808
CAS :<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Formule :C17H19FN4Couleur et forme :SolidMasse moléculaire :298.36Protein kinase inhibitor H-7
CAS :<p>H-7: potent PKC inhibitor with 6 μM Ki, also blocks cyclic nucleotide-dependent kinases.</p>Formule :C14H17N3O2SDegré de pureté :99.91%Couleur et forme :SoildMasse moléculaire :291.37Modified MMAF
CAS :<p>Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.</p>Formule :C45H73N7O8Couleur et forme :SolidMasse moléculaire :840.1Coronaridine
CAS :<p>Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.</p>Formule :C21H26N2O2Couleur et forme :SolidMasse moléculaire :338.451PROTAC HSP90 degrader BP3
CAS :<p>PROTAC BP3 selectively degrades HSP90, inhibits breast cancer growth (DC50=0.99µM), CRBN-dependent.</p>Formule :C32H29ClN8O5Couleur et forme :SolidMasse moléculaire :641.08IIQLPEIVVV TFA
<p>IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.</p>Formule :C54H95N11O14·xC2HF3O2Couleur et forme :SolidMasse moléculaire :1122.40 (free base)αVβ8-IN-1
CAS :<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.01PDI-IN-4
<p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>Formule :C17H12F3NO2Couleur et forme :SolidMasse moléculaire :319.278Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.1117-DMAP-GA
CAS :<p>17-DMAP-GA, a Geldanamycin analogue, acts as an HSP90 inhibitor, leading to cell cycle abnormalities.</p>Formule :C33H50N4O8Couleur et forme :SolidMasse moléculaire :630.783LY 379196
<p>LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.</p>Formule :C30H34N4O5SCouleur et forme :SolidMasse moléculaire :562.68Hypoglycemic agent 3
<p>Compound H26, a derivative of corosolic acid, functions as Hypoglycemic agent 3. It exhibits lipid-lowering and significant blood glucose-reducing properties, making it a potential hypoglycemic drug. Hypoglycemic agent 3 targets MCCC1 to mitigate insulin resistance, and may be useful in researching type 2 diabetes.</p>Formule :C32H51NO5Couleur et forme :SolidMasse moléculaire :529.751GRGDSPK
CAS :<p>GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.</p>Formule :C28H49N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.76Tubulin polymerization-IN-48
<p>Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.</p>Formule :C20H15Cl2N3OCouleur et forme :SolidMasse moléculaire :384.26BCR-ABL-IN-3
CAS :<p>BCR-ABL-IN-3 irreversibly inhibits Bcr-Abl with <100 nM IC50, showing significant anti-cancer effects.</p>Formule :C20H17ClF2N4O3SCouleur et forme :SolidMasse moléculaire :466.89Tubulin inhibitor 37
<p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>Formule :C16H10Cl2N6OCouleur et forme :SolidMasse moléculaire :373.2hBChE-IN-1
CAS :<p>"hBChE-IN-1, a quinolizidine, potently inhibits hBChE (IC50=7nM), selective over hAChE, and blocks tau and Aβ 40 aggregation for Alzheimer's research."</p>Formule :C27H34N2OS2Couleur et forme :SolidMasse moléculaire :466.70NU074381b
<p>NU074381b (compound 5b) is an effective inhibitor of S100A4, disrupting the formation of the S100A4-NMII complex with an IC50 value of 0.48 µM. Additionally, it inhibits cell proliferation and migration.</p>Formule :C23H25ClN2O2Couleur et forme :SolidMasse moléculaire :396.91AKT Kinase Inhibitor HCl
<p>AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.</p>Formule :C16H20ClN7O3Degré de pureté :98.63%Couleur et forme :SoildMasse moléculaire :393.83Rotigaptide
CAS :<p>Rotigaptide, modulates Cx43 for gap junctions, counteracts uncoupling, and maintains communication under stress.</p>Formule :C28H39N7O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :617.65GSK3178022
<p>GSK3178022 is a human IgG1 monoclonal antibody (mAb) that targets LRP6. It inhibits the expression of the WNT target genes SP5 and AXIN2 and demonstrates antitumor activity in colorectal cancer RSPO fusion models. The recommended isotype control is HumanIgG1kappa, Isotype Control.</p>Couleur et forme :Odour LiquidPROTAC BCR-ABL Degrader-1
<p>PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and</p>Formule :C43H40N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :792.84Crosstide
CAS :<p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>Formule :C48H77N17O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1164.23Pironetin
CAS :<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45ALB-109564 dihydrochloride
CAS :<p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>Formule :C47H62Cl2N4O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :929.99Catumaxomab
CAS :<p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>Degré de pureté :95%Couleur et forme :LiquidBIO5192 hydrate
<p>BIO5192 hydrate: potent α4β1 inhibitor, binds selectively (Kd<10 pM, IC50=1.8 nM), boosts murine HSPC mobilization 30x.</p>Couleur et forme :SolidTubulin inhibitor 48
CAS :<p>Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.</p>Formule :C21H22N4OCouleur et forme :SolidMasse moléculaire :346.43BMP agonist 1
<p>BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.</p>Formule :C21H16N2O6Couleur et forme :SolidMasse moléculaire :392.36[Ala113]MBP(104-118)
CAS :<p>Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).</p>Formule :C67H104N20O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1493.68Tyrosine kinase-IN-8
<p>Tyrosine kinase-IN-8 (compound 4e) is a BCR‐ABL1 tyrosine kinase inhibitor (TKI) exhibiting antiproliferative activity against the chronic myeloid leukemia (CML) cell line K562, with a CC50 of 0.8 µM. Tyrosine kinase-IN-8 is applicable for research in chronic leukemia.</p>Formule :C31H21F2N7O2Masse moléculaire :561.17248cSRC/BCR-ABL1-IN-1
<p>cSRC/BCR-ABL1-IN-1 (compound 16a) is a dual-target inhibitor of the cSRC/BCR-ABL1 kinases.</p>Formule :C24H27ClN6O4Couleur et forme :SolidMasse moléculaire :498.96hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45Protein Kinase C (19-31) (TFA)(121545-65-1,free)
<p>Protein Kinase C (19-31) TFA is a serine-modified PKCa-derived inhibitor for testing PKC activity.</p>Formule :C69H119F3N26O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1657.84αvβ6-IN-1
<p>αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.</p>Formule :C25H32F2N4O3Couleur et forme :SolidMasse moléculaire :474.54Anticancer agent 139
<p>Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high</p>Formule :C16H12F3N3OCouleur et forme :SolidMasse moléculaire :319.28Aβ-IN-1 TFA
<p>Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.</p>Formule :C37H50F3NO2Degré de pureté :99.82%Couleur et forme :SoildMasse moléculaire :597.79αvβ6-IN-2
<p>αvβ6-IN-2 (compound 20) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 7.8. It shows potential for use in research on idiopathic pulmonary fibrosis.</p>Formule :C25H30F3N3O3Couleur et forme :SolidMasse moléculaire :477.52EMD527040
CAS :<p>EMD527040 is a potent αvβ6 antagonist with antifibrotic effects, used in carcinoma and liver fibrosis research.</p>Formule :C29H32Cl2N4O5Couleur et forme :SolidMasse moléculaire :587.5Microtubule stabilizing agent-1
<p>Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [</p>Formule :C45H55NO13Couleur et forme :SolidMasse moléculaire :817.92Anticancer agent 270
<p>Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.</p>Couleur et forme :Odour SolidMT189
CAS :<p>MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.</p>Formule :C21H18FN3O2Degré de pureté :98.52%Couleur et forme :SoildMasse moléculaire :363.38ML 2-23
<p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>Formule :C47H53BrCl2N10O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1052.86Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidMasse moléculaire :150 kDaProtein Kinase C (19-36)
CAS :<p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>Formule :C93H159N35O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2151.48BCR-ABL-IN-9
<p>BCR-ABL-IN-9 (Compound B1) is an inhibitor of BCR-ABL that achieves sustained suppression through the formation of stable covalent bonds with the ABL kinase. It effectively inhibits the activity of ABL kinase (IC50 = 1.2 nM) and possesses anticancer activity.</p>Formule :C22H20N4O3Couleur et forme :SolidMasse moléculaire :388.42TNIR7-1A
CAS :<p>TNIR7-1A is a fused cycloheptatriene-BODIPY derivative that is optimized for near-infrared (NIR) imaging characteristics (Ex/Em = 600/774 nm in PBS) and exhibits high affinity and specificity for neurofibrillary tangles (NFT) in vitro. Additionally, TNIR7-1A can effectively penetrate the blood-brain barrier.</p>Formule :C23H20BF2N3Couleur et forme :SolidMasse moléculaire :387.23Bimosiamose
CAS :<p>Bimosiamose has anti-inflammatory effects[1].</p>Formule :C46H54O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :862.91HA15-Biotin
CAS :<p>HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.</p>Formule :C37H45N7O5S3Couleur et forme :SolidMasse moléculaire :763.99ICAM-1988
CAS :<p>ICAM-1988 is a LFA-1 antagonist.</p>Formule :C22H22Cl2N4O6SCouleur et forme :SolidMasse moléculaire :541.4GSK-3β inhibitor 21
<p>GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.</p>Couleur et forme :Odour SolidGanodermaones B
<p>Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43Wnt pathway inhibitor 4
CAS :<p>Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells.</p>Formule :C19H15BrN2O5Degré de pureté :97.66%Couleur et forme :SolidMasse moléculaire :431.24HSDVHK-NH2
CAS :<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Formule :C30H48N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :720.78Epothilone F
CAS :<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68α2β1 Integrin Ligand Peptide TFA
<p>α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a</p>Formule :C16H23F3N4O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.37Asperosaponin V
CAS :<p>Asperosaponin V is a useful organic compound for research related to life sciences. The catalog number is T126228 and the CAS number is 120481-38-1.</p>Formule :C47H76O17Couleur et forme :SolidMasse moléculaire :913.108Hsp70-derived octapeptide
CAS :<p>TPR proteins including CHIP, TPR1, and hSGT affect luciferase refolding by DnaJ and hsc70.</p>Formule :C36H58N8O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :858.89Foxy-5
CAS :<p>Foxy-5 is a wnt5a peptide mimetic</p>Formule :C26H42N6O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :694.77Combretastatin A-1 phosphate tetrasodium
CAS :<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Formule :C18H18Na4O12P2Couleur et forme :SolidMasse moléculaire :580.2411H-Benzo[a]carbazole
CAS :<p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>Formule :C16H11NDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :217.27DSPE-PEG1000-iRGD
<p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>Couleur et forme :Odour SolidSNIPER(ABL)-058
CAS :<p>SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein</p>Formule :C62H75N11O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1150.393-Phenyltoxoflavin
CAS :<p>3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.</p>Formule :C13H11N5O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :269.26Maydispenoid B
<p>Maydispenoid B suppresses immune response, halts mouse spleen cell growth.</p>Formule :C25H34O4Couleur et forme :SolidMasse moléculaire :398.54Betamethasone 17-benzoate
CAS :<p>Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).</p>Formule :C29H33FO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :496.57MS170
CAS :<p>MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.</p>Formule :C45H56ClN9O7Couleur et forme :SolidMasse moléculaire :870.45PDS-0330
CAS :<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Formule :C25H17N3O2SDegré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :423.49Phomopsin A
CAS :<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formule :C36H45ClN6O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :789.23Dafsolimab
CAS :<p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>Couleur et forme :LiquidP8RI acetate
<p>P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.</p>Formule :C53H81N13O11Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :1076.29Larazotide
CAS :<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Formule :C32H55N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :725.83Bifidenone
CAS :<p>Bifidenone is an effective tubulin polymerization inhibitor.</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43HSP70-IN-3
<p>HSP70-IN-3: Strong HSP70 blocker; IC50=1.1μM/1.9μM (ASZ001/C3H10T1/2); hinders Hedgehog signaling and cancer cell growth, lowers GLI1 levels.</p>Formule :C48H78N6O7SCouleur et forme :SolidMasse moléculaire :883.23Tubulin Polymerization-IN-1 prodrug
CAS :<p>Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.</p>Formule :C22H23FN2O4Couleur et forme :SolidMasse moléculaire :398.43PROTAC Hsp90α degrader 1
<p>Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.</p>Formule :C43H50N6O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :762.89MK2-IN-5
CAS :<p>MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway and</p>Formule :C61H113N21O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1396.68hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Couleur et forme :Odour SolidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Couleur et forme :Odour SolidSangivamycin
CAS :<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Formule :C12H15N5O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :309.28Fasudil
CAS :<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37Tubulin polymerization-IN-53
<p>Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.</p>Couleur et forme :Odour SolidAT7867 dihydrochloride
CAS :<p>AT7867 dihydrochloride inhibits Akt1/2/3 and p70S6K/PKA, with IC50s: 32/17/47 nM & 85/20 nM, respectively, and hampers tumor growth.</p>Formule :C20H22Cl3N3Couleur et forme :SolidMasse moléculaire :410.77Trifluralin
CAS :<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Formule :C13H16F3N3O4Degré de pureté :99.84%Couleur et forme :Yellow-Orange Crystalline SolidMasse moléculaire :335.28TTBK1-IN-1
CAS :<p>TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.</p>Formule :C18H19N5O2Couleur et forme :SolidMasse moléculaire :337.38Lixisenatide
CAS :<p>Lixisenatide: Injectable GLP-1 agonist for T2DM, controls blood sugar.</p>Formule :C215H347N61O65SCouleur et forme :SolidMasse moléculaire :4858.49NSC305787 hydrochloride
CAS :<p>NSC305787 hydrochloride ((Rac)-NSC305787 hydrochloride is a Cdc25 dual specificity phosphatase and EZR inhibitor with antitumor activity and inhibits Cdc25B2.</p>Formule :C25H31Cl3N2ODegré de pureté :99.07% - 99.07%Couleur et forme :SolidMasse moléculaire :481.89Miransertib hydrochloride
CAS :<p>Miransertib hydrochloride is an orally active, selective, allosteric pan-Akt inhibitor that also demonstrates potent activity against Leishmania parasites.</p>Formule :C27H25ClN6Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :468.98DOTA-cyclo(RGDfK)
CAS :<p>DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.</p>Formule :C43H67N13O14Couleur et forme :SoildMasse moléculaire :990.07Tonabersat
CAS :<p>Tonabersat (SB-220453) is a novel and orally available gap-junction modulator and CSD (Cortical spreading depression) inhibitor that,migraine and epilepsy.</p>Formule :C20H19ClFNO4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :391.82Blinatumomab
CAS :<p>Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.</p>Couleur et forme :LiquidAnti-Mouse CD3 Antibody (17A2)
<p>Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.</p>Couleur et forme :Odour LiquidMK-0429
CAS :<p>MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).</p>Formule :C23H29N5O4Couleur et forme :SolidMasse moléculaire :439.51xStAx-VHLL TFA
<p>xStAx-VHLL TFA is a β-catenin degrader formed by coupling xStAx to VHL ligand, with anti-cancer activity and inhibition of Wnt signaling.</p>Formule :C154H244N48O29·xC2HF3O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :3231.89 (free base)Avanbulin
CAS :<p>Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.</p>Formule :C20H17N7O2Couleur et forme :SolidMasse moléculaire :387.39Danegaptide
CAS :<p>Danegaptide (GAP-134) is a potent, second-gen, oral gap junction modifier; a small modified dipeptide.</p>Formule :C14H17N3O4Couleur et forme :SolidMasse moléculaire :291.3CCT245232
CAS :<p>CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.</p>Formule :C27H23N3O4Couleur et forme :SolidMasse moléculaire :453.49Lifitegrast sodium
CAS :<p>Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.</p>Formule :C29H23Cl2N2NaO7SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :637.46Amiprofos methyl
CAS :<p>Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.</p>Formule :C11H17N2O4PSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :304.30Latrunculin A
CAS :<p>Latrunculin A, a toxin from the sponge Latrunculia magnifica, binds and inhibits actin polymerization (Kds: 0.1-4.7 μM).</p>Formule :C22H31NO5SDegré de pureté :98%Couleur et forme :Waxy SolidMasse moléculaire :421.55Asciminib hydrochloride
CAS :<p>Asciminib (ABL001) hydrochloride is a selective and potent mutant BCR-ABL1 inhibitor that inhibits Ba/F3 cell growth (IC50: 0.25 nM).</p>Formule :C20H19Cl2F2N5O3Couleur et forme :SolidMasse moléculaire :486.3(±)-1,2-Diolein
CAS :<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Formule :C39H72O5Couleur et forme :SolidMasse moléculaire :620.99Debio 0932
CAS :<p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>Formule :C22H30N6O2SDegré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :442.58AZ82
CAS :<p>AZ82 is an inhibitor of the kinesin-like protein KIFC1, which induces multipolar mitosis and apoptosis in prostate cancer cells.</p>Formule :C28H31F3N4O3SDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :560.63Ombrabulin hydrochloride
CAS :<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Formule :C21H27ClN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.9Kinesore
CAS :<p>Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.</p>Formule :C20H16Br2N4O4Degré de pureté :97.24%Couleur et forme :SolidMasse moléculaire :536.17PKC-θ inhibitor
CAS :<p>PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.</p>Formule :C20H25F3N6O3Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :454.45PU-H71
CAS :<p>PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.</p>Formule :C18H21IN6O2SDegré de pureté :98.31% - 99.937%Couleur et forme :SolidMasse moléculaire :512.37GW406108X
CAS :<p>GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.</p>Formule :C20H11Cl2NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.21ADH-1
CAS :<p>ADH-1 (Exherin) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.</p>Formule :C22H34N8O6S2Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :570.69Ipfencarbazone
CAS :<p>Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.</p>Formule :C18H14Cl2F2N4O2Couleur et forme :SolidMasse moléculaire :427.23GPRP
CAS :<p>GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.</p>Formule :C18H31N7O5Couleur et forme :White To Off-White PowderMasse moléculaire :425.48SY-LB-35
CAS :<p>SY-LB-35 is a potent BMP receptor agonist enhancing cell growth and viability in C2C12, affecting cell cycle and signaling pathways.</p>Formule :C15H11N3OCouleur et forme :SolidMasse moléculaire :249.27PhosTAC7
CAS :<p>PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.</p>Formule :C58H87ClN2O17Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :1119.77colchiceine
CAS :<p>colchiceine has a wide range of applications in life science related research.</p>Formule :C21H23NO6Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :385.41Cilengitide TFA
CAS :<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68Palmitic acid-1-13C
CAS :<p>Palmitic acid-13C, a 16-C saturated fatty acid internal standard for GC/LC-MS, is prevalent in plasma lipids and influences protein acylation and COX-2 levels.</p>Formule :C16H32O2Couleur et forme :SolidMasse moléculaire :257.422Protein kinase inhibitor H-7 dihydrochloride
CAS :<p>Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.</p>Formule :C14H19Cl2N3O2SDegré de pureté :99.54%Couleur et forme :White Crystalline SolidMasse moléculaire :364.29Oryzalin
CAS :<p>Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.</p>Formule :C12H18N4O6SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :346.36BSc3094
CAS :<p>BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.</p>Formule :C17H12N6O3SCouleur et forme :SolidMasse moléculaire :380.38Ulacamten
CAS :<p>Ulacamten is an effective inhibitor of cardiac myosin (cardiacmyosin).</p>Formule :C21H25F2N3O3Couleur et forme :SolidMasse moléculaire :405.44RGD Trifluoroacetate
CAS :<p>RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.</p>Formule :C14H23F3N6O8Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :460.36Combretastatin A-1
CAS :<p>Combretastatin A-1 is a microtubule inhibitor with anti-tumour and can be used to study liver cancer.</p>Formule :C18H20O6Degré de pureté :97.49% - 97.49%Couleur et forme :SolidMasse moléculaire :332.35Yoda 1
CAS :<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Formule :C13H8Cl2N4S2Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :355.27GNF-7
CAS :<p>GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.</p>Formule :C28H24F3N7O2Degré de pureté :97.05% - 99.7%Couleur et forme :SolidMasse moléculaire :547.53TRC051384
CAS :<p>TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.</p>Formule :C25H31N5O4Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :465.54Eptifibatide acetate (148031-34-9 free base)
CAS :<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formule :C35H49N11O9S2·xC2H4O2Degré de pureté :99.7% - 99.87%Couleur et forme :SolidMasse moléculaire :831.96 (free base)Spastazoline
CAS :<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formule :C20H30N8Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :382.51Benproperine phosphate
CAS :<p>Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.</p>Formule :C21H30NO5PDegré de pureté :99.84%Couleur et forme :PowderMasse moléculaire :407.44Valrubicin
CAS :<p>Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.</p>Formule :C34H36F3NO13Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :723.64Tianeptine sodium salt
CAS :<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formule :C21H24ClN2NaO4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :458.93E7820
CAS :<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formule :C17H12N4O2SDegré de pureté :98.31% - 99.11%Couleur et forme :SolidMasse moléculaire :336.37AG957
CAS :<p>Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in</p>Formule :C15H15NO4Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :273.28Doxepin
CAS :<p>Doxepin: tricyclic antidepressant, inhibits serotonin/norepinephrine reuptake, helps atopic dermatitis/urticaria, cognitive protector, anti-inflammatory.</p>Formule :C19H21NOCouleur et forme :SolidMasse moléculaire :279.38Orbofiban
CAS :<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Formule :C17H23N5O4Couleur et forme :SolidMasse moléculaire :361.4Rebastinib
CAS :<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formule :C30H28FN7O3Degré de pureté :99.53% - 99.79%Couleur et forme :SolidMasse moléculaire :553.59Valecobulin
CAS :<p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>Formule :C26H28N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.6Questiomycin A
CAS :<p>Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.</p>Formule :C12H8N2O2Degré de pureté :98.13% - 98.7%Couleur et forme :SolidMasse moléculaire :212.2Albendazole sulfoxide
CAS :<p>Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.</p>Formule :C12H15N3O3SDegré de pureté :97.29%Couleur et forme :White To Off-White PowderMasse moléculaire :281.33PF-431396
CAS :<p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>Formule :C22H21F3N6O3SDegré de pureté :98.83% - 99.82%Couleur et forme :SolidMasse moléculaire :506.5Asciminib
CAS :<p>Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).</p>Formule :C20H18ClF2N5O3Degré de pureté :98.82% - 99.70%Couleur et forme :SolidMasse moléculaire :449.84Trimethyloctadecylammonium bromide
CAS :<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Formule :C21H46N·BrDegré de pureté :99.09%Couleur et forme :Solid SolidMasse moléculaire :392.5NVP-BAW2881
CAS :<p>NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.</p>Formule :C22H15F3N4O2Degré de pureté :98.19% - 99.97%Couleur et forme :SolidMasse moléculaire :424.38KW-2449
CAS :<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formule :C20H20N4ODegré de pureté :98.43% - 99.69%Couleur et forme :SolidMasse moléculaire :332.4Cyclo(RADfK)
CAS :<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Formule :C28H43N9O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :617.7IM-12
CAS :<p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>Formule :C22H20FN3O2Degré de pureté :99.42% - >99.99%Couleur et forme :SolidMasse moléculaire :377.41Shepherdin 79-87 acetate
<p>Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.</p>Formule :C43H68N12O14SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :1009.14KBU2046
CAS :<p>KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.</p>Formule :C15H11FO2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :242.24SMIFH2
CAS :<p>SMIFH2 is formin homology 2 (FH2) domains inhibitor.</p>Formule :C15H9BrN2O3SDegré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :377.21Pamidronate disodium pentahydrate
CAS :<p>Pamidronate disodium pentahydrate strengthens bones and prevents osteoporosis.</p>Formule :C3H21NNa2O12P2Degré de pureté :99.84%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :371.13Teduglutide acetate
<p>Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy.</p>Formule :C166H256N44O56SDegré de pureté :97.39%Couleur et forme :SoildMasse moléculaire :3812.132-hydroxy Flutamide
CAS :<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Formule :C11H11F3N2O4Degré de pureté :99.45% - 99.82%Couleur et forme :SolidMasse moléculaire :292.21VER49009
CAS :<p>VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).</p>Formule :C19H18ClN3O4Degré de pureté :98.95% - >99.99%Couleur et forme :SolidMasse moléculaire :387.82CW-069
CAS :<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Formule :C23H21IN2O3Degré de pureté :97.52% - 99.52%Couleur et forme :SolidMasse moléculaire :500.33Multi-kinase inhibitor 1
CAS :<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37[Ala107]-MBP (104-118) acetate
<p>[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).</p>Formule :C59H108N20O21Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :1553.72roxifiban
CAS :<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Formule :C21H29N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.48HSP70-IN-1
CAS :<p>HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).</p>Formule :C24H28N6O2SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :464.58NRX-252262
CAS :<p>NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50：3.8 nM)</p>Formule :C23H17Cl2F3N2O4SDegré de pureté :98.94% - 99.87%Couleur et forme :SolidMasse moléculaire :545.36CTX-0294885
CAS :<p>CTX-0294885, a bisanilino pyrimidine, inhibits many kinases; used for Sepharose-based kinase capture.</p>Formule :C22H24ClN7ODegré de pureté :98.73% - ≥95%Couleur et forme :SolidMasse moléculaire :437.93Olverembatinib
CAS :<p>Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).</p>Formule :C29H27F3N6ODegré de pureté :98.53% - >99.99%Couleur et forme :SolidMasse moléculaire :532.56Defactinib
CAS :<p>Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.</p>Formule :C20H21F3N8O3SDegré de pureté :98% - 99.71%Couleur et forme :SolidMasse moléculaire :510.49HA-100
CAS :<p>HA-100 is an inhibitor of protein kinase</p>Formule :C13H15N3O2SDegré de pureté :99.44%Couleur et forme :Pale Yellow Crystalline SolidMasse moléculaire :277.34Dynamin inhibitory peptide, myristoylated acetate
<p>Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.</p>Formule :C63H111N19O16Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :1390.67Bisindolylmaleimide V
CAS :<p>Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.</p>Formule :C21H15N3O2Degré de pureté :90%Couleur et forme :Red SolidMasse moléculaire :341.36Chelerythrine
CAS :<p>1.</p>Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37MitoBloCK-10
CAS :<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Formule :C12H8FN3O3SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :293.27PKC-iota inhibitor 1
CAS :<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44TB500
CAS :<p>TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.</p>Formule :C38H68N10O14Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :889.01BIO-1211
CAS :<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8GMB-475
CAS :<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formule :C43H46F3N7O7SDegré de pureté :98.78% - >99.99%Couleur et forme :SolidMasse moléculaire :861.93CK-636
CAS :<p>CK-636 (CK-0944636), an Arp2/3 complex inhibitor, can inhibit actin polymerization induced by the human, fission yeast and bovine Arp2/3 complex.</p>Formule :C16H16N2OSDegré de pureté :98.1% - 98.88%Couleur et forme :SolidMasse moléculaire :284.38Clanfenur
CAS :<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Formule :C16H15ClFN3O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :335.76HM03 trihydrochloride
CAS :<p>HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.</p>Formule :C26H30Cl4N4O2Couleur et forme :SolidMasse moléculaire :572.35TNIK-IN-2
CAS :<p>TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.</p>Formule :C22H19N3O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :373.4Smurf1-IN-A01
CAS :<p>Smurf1-IN-A01 is a potent Smurf1 inhibitor enhancing BMP-2, with a Kd of 3.664 nM, preventing Smad1/5 degradation.</p>Formule :C22H20ClF3N4O3SDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :512.93Tirofiban hydrochloride monohydrate
CAS :<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formule :C22H39ClN2O6SDegré de pureté :98.81% - >99.99%Couleur et forme :White SolidMasse moléculaire :495.07MK2-IN-1 hydrochloride
CAS :<p>MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.</p>Formule :C27H26Cl2N4O2Degré de pureté :97.32%Couleur et forme :SolidMasse moléculaire :509.43Plinabulin
CAS :<p>Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).</p>Formule :C19H20N4O2Degré de pureté :98.69% - >99.99%Couleur et forme :SolidMasse moléculaire :336.39Hypocrellin A
CAS :<p>Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.</p>Formule :C30H26O10Degré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :546.52Y15
CAS :<p>Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity,</p>Formule :C6H14Cl4N4Degré de pureté :98% - 99.32%Couleur et forme :Dark Brown CrystalsMasse moléculaire :284.01Suprafenacine
CAS :<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Formule :C16H18N4ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :282.34AG1024
CAS :<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formule :C14H13BrN2ODegré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :305.17S-trityl-L-Cysteine
CAS :<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Formule :C22H21NO2SDegré de pureté :97.02%Couleur et forme :Almost White To Light Yellow Granular PowderMasse moléculaire :363.47PU-H54
CAS :<p>PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.</p>Formule :C18H19N5SDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :337.44Daphnetin
CAS :<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14A-286982
CAS :<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formule :C24H27N3O4SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :453.55
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