Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1585 produits trouvés pour "Signalisation du cytosquelette"
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Akt/SKG Substrate Peptide
CAS :substrate for Akt/PKBFormule :C36H59N13O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :817.94Tubulin Polymerization-IN-1 prodrug
CAS :Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.Formule :C22H23FN2O4Couleur et forme :SolidMasse moléculaire :398.43Fibrinogen Binding Inhibitor Peptide
CAS :Synthetic dodecapeptide mimics human fibrinogen g-chain, inhibits platelet receptor (residues 400-411).Formule :C50H80N18O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1189.28Anticancer agent 270
Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.Couleur et forme :Odour SolidEudebeiolide B
CAS :Eudebeiolide B, isolated from Salvia plebeia R.Formule :C15H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.3Neuropeptide DF2
CAS :Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish.Formule :C44H67N15O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :966.1Tubulin inhibitor 24
CAS :Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formule :C22H21N3O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :375.42BRM/BRG1 ligand 3
CAS :BRM/BRG1 ligand 3 is a target protein ligand utilized in the synthesis of PROTAC BRM/BRG1 degrader-3.Formule :C19H24N6OCouleur et forme :SolidMasse moléculaire :352.43RA-PR058
RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.Formule :C11H15ClF3N3OCouleur et forme :SolidMasse moléculaire :297.7Davunetide
CAS :Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.Formule :C36H60N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :824.92Jatrophone
CAS :Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.Formule :C20H24O3Couleur et forme :SolidMasse moléculaire :312.4DSPE-PEG3400-cRGD
DSPE-PEG3400-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 integrins present on the surface of various cancer cells and neovascularization cells. DSPE-PEG3400-cRGD can be utilized for drug delivery purposes.Couleur et forme :Odour SolidTRAP-14 amide
CAS :TRAP-14 amide is a protease-activated receptor (PAR) activating peptide and acts as a PAR agonist, with an EC50 of 24 μM. It induces significant platelet aggregation via ADP and MMP-2 dependent pathways and is insensitive to Aspirin. Additionally, TRAP-14 amide effectively increases the surface expression of glycoprotein (GP) Ib and GPIIb/IIIa, as well as the release of ADP.Formule :C81H119N21O22Couleur et forme :SolidMasse moléculaire :1738.94G-5555 hydrochloride (1648863-90-4 free base)
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.Formule :C25H26Cl2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.42MS143
CAS :MS143: potent AKT degrader, DC50=46 nM, GI50=0.8 µM in PC3 cells, degrades AKT via ubiquitin-proteasome, suppresses cancer growth.Formule :C59H81ClN12O6SCouleur et forme :SolidMasse moléculaire :1121.87Cy5-Paclitaxel
Cy5-Paclitaxel is a Cy5-labeled paclitaxel conjugate. Cy5 is a cyanine dye (with an approximate wavelength of 662 nm) utilized in molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization, causing mitotic arrest and apoptotic death. It also induces autophagy.Formule :C93H104N4O16Couleur et forme :SolidMasse moléculaire :1533.84Cyclo(RGDyK)
CAS :Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formule :C27H41N9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.68FKKSFKL-NH2
CAS :FKKSFKL-NH2 is a selective peptide for protein kinase C, employed in biochemical research [1].Formule :C45H73N11O8Couleur et forme :SolidMasse moléculaire :896.13K34c hydrochloride
CAS :K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Formule :C26H30ClN3O4Degré de pureté :99.76% - 99.89%Couleur et forme :SoildMasse moléculaire :483.99PM050489
CAS :PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.Formule :C31H44ClN3O7Couleur et forme :SolidMasse moléculaire :606.15
