
Toxicologie
13594 produits trouvés pour "Toxicologie"
Bis(dithiarsolanyl)-bis(sulfobutyl) Cyanine 3
CAS :Applications A red Cy3-based biarsenical fluorescent probe targeted to a complementary binding peptide. AsCy3 has good photostability, low pH sensitivity, high absorbance, and good quantum yield. This new probe provides a FRET partner to biarsenical dye FlAsH, making this discovery an important step toward a whole toolkit of colored probes directed to different small peptide motifs.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cao, H., et al.: J. Am. Chem. Soc., 129, 8672 (2007)Formule :C35H46As2N2O6S6Couleur et forme :NeatMasse moléculaire :932.98Chloramphenicol 3-O-β-D-Glucuronide
CAS :Applications The major glucuronide metabolite of Chloramphenicol (C325030).
References Simons, P., et al.: Xenobiotica, 22, 1267 (1992), Kaji, H., et al.: Drug Metab. Dispos., 33, 60 (2005),Formule :C17H20Cl2N2O11Couleur et forme :Off-WhiteMasse moléculaire :499.253,5-Dimethyl-4-(methylthio)phenol
CAS :Produit contrôléApplications 3,5-Dimethyl-4-(methylthio)phenol is used as an insecticide and used the synthesis of methiocarb.
References Yamada, K. et al.: J. Health Sci., 57, 134 (2011); Keum, Y. et al.: Chromatograph., 52, 237 (2000);Formule :C9H12OSCouleur et forme :NeatMasse moléculaire :168.26Propentofylline
CAS :Produit contrôléFormule :C15H22N4O3Couleur et forme :White To Off-WhiteMasse moléculaire :306.363-O-(Codein-2-yl)morphine (1.0mg/ml in Methanol)
CAS :Produit contrôléFormule :C35H38N2O6Couleur et forme :Clear ColourlessMasse moléculaire :582.694-Methoxy Estrone
CAS :Produit contrôléApplications An endogenous estrogen metabolite, risk-factor for development of breast cancer.
References Beral, V., et al.: Lancet, 362, 419 (2003), Nelson, R., et al.: Clin. Chem., 50, 373 (2004), Malekinejad, H., et al.: J. Agric. Food Chem., 54, 9785 (2006),Formule :C19H24O3Couleur et forme :Off White SolidMasse moléculaire :300.39Hexamethylenetetramine-d12
CAS :Produit contrôléApplications Labelled Methenamine (H294220). Used in the treatment of urinary track infection.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Day, G.M., et al.: J. Physical Chem., 107, 10919 (2003),Formule :C6D12N4Couleur et forme :NeatMasse moléculaire :152.26Malathion β-Monoacid
CAS :Stability Hygroscopic
Applications A major biodegradation product of Malathion (M111000).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);Formule :C8H15O6PS2Couleur et forme :NeatMasse moléculaire :302.32-Amino-4-(methylsulfonyl)benzoic Acid
CAS :Applications 2-Amino-4-(methylsulfonyl)benzoic Acid is a reagent used in the synthesis of anthranilic diamides containing fluorinated groups as potential ryanodine receptors activators.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wu, C. et al.: Chem. Lett., 28, 1248 (2017);Formule :C8H9NO4SCouleur et forme :NeatMasse moléculaire :215.23Cyantraniliprole
CAS :Produit contrôléApplications Cyantraniliprole is used as an insecticide and/or acaricide. Also useful in cannabis testing kits as a component of pesticide mixes (P698240).
References Abbott, W., et al.: J. Econ. Entomol., 18, 265 (1925), Ali, A., et al.: Environ. Entomol., 19, 1066 (1990),Formule :C19H14BrClN6O2Couleur et forme :BeigeMasse moléculaire :473.71Lidocaine-d6 Hydrochloride
CAS :Produit contrôléApplications Lidocaine-d6 Hydrochloride is the labeled analogue of Lidocaine Hydrochloride, a local anesthetic; antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971), Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973), Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),Formule :C14H17D6ClN2OCouleur et forme :NeatMasse moléculaire :276.84Mesosulfuron-methyl
CAS :Stability Unstable in Solution
Applications Mesosulfuron-methyl can be used in biological study of targeted screening and safety evaluation of 276 agrochemical residues in raisins using buffered ethyl acetate extraction and liquid chromatography-tandem mass spectrometry analysis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shabeer, T. P. A., et al.: Chemosphere, 184, 1036 (2017)Formule :C17H21N5O9S2Couleur et forme :NeatMasse moléculaire :503.512-Chlorobenzonitrile
CAS :Applications 2-Chlorobenzonitrile is an activated aryl chloride that is commonly used in reactions that involve the Palladium-catalyzed direct arylation of heteroaromatics (e.g. 3-aminopicolinic acid [A627800]). 2-Chlorobenzonitrile and its substituted derivatives (e.g. 2,3-dichloro-6-nitrobenzonitrile [2112-22-3]) also have potential anti-inflammatory properties.
References Andreu, M., et al.: Chem. Commun., 24, 2475 (2000); Hellman, W., et al.: J. Med. Chem., 21, 906 (1978); Roy, D., et al.: ACS Catal., 2, 1033 (2012);Formule :C7H4ClNCouleur et forme :NeatMasse moléculaire :137.574-Chloroaniline-d4
CAS :Produit contrôléFormule :C6D4H2ClNCouleur et forme :Light Brown To GreyMasse moléculaire :131.6Iso Cyclosporin H Trifluoroacetic Acid Salt
CAS :Stability Hygroscopic
Applications Iso Cyclosporin H is an impurity of Cyclosporin H (C988920).
References Borel, J., et al.: Pharmacol. Rev., 41, 259 (1990); Brooks, C., et al.: Clin. Chem., 39, 457 (1993); Lee, Y., et al.: J. Pharm. Biomed. Anal., 22, 183 (2000);Formule :C62H111N11O12·x(C2HF3O2)Degré de pureté :>75% by HPLCCouleur et forme :NeatMasse moléculaire :1202.6Rizatriptan-d6 Benzoate
CAS :Produit contrôléFormule :C22H19D6N5O2Couleur et forme :NeatMasse moléculaire :397.5N,N-Dimethylnicotinamide-2-sulfonamide
CAS :Produit contrôléApplications N,N-Dimethylnicotinamide-2-sulfonamide (cas# 112006-75-4) is a compound useful in organic synthesis.
Formule :C8H11N3O3SCouleur et forme :NeatMasse moléculaire :229.26Myristoyl-L-carnitine-d3 Hydrochloride
CAS :Produit contrôléStability Hygroscopic
Applications Myristoyl-L-carnitine-d3 Hydrochloride is labelled Myristoyl-L-carnitine Hydrochloride (M884745), a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ß-oxidation defects.
References Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)Formule :C21D3H39NO4·ClCouleur et forme :Off-WhiteMasse moléculaire :411.034alpha-Hydroxy Metoprolol (Mixture of Diastereomers)
CAS :Produit contrôléApplications A metabolite of Metoprolol.
References Lennard, M.S., et al.: Br. J. Clin. Pharmacol., 14, 713 (1982), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 36, 320 (1984),Formule :C15H25NO4Couleur et forme :Off-White To BeigeMasse moléculaire :283.36Rapamycin-13C,d3 (contains d0) Technical Grade
CAS :Produit contrôléApplications Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic.This compound contains aproximately 2% d0.
References Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),Formule :C50CH76D3NO13Couleur et forme :NeatMasse moléculaire :918.18Etifoxine Hydrochloride
CAS :Applications Psychotropic agent with anxiolytic and anticonvulsant activity.
References Boissier, J.R., et al.: Therapie, 27, 325 (1972), Bente, D., et al.: Arzneim. Forsch., 25, 944 (1975),Formule :C17H17ClN2O·ClHCouleur et forme :Off White SolidMasse moléculaire :337.24Pyroxsulam Sulfonic Acid Sodium Salt
Produit contrôléFormule :C7H5F3NNaO4SCouleur et forme :NeatMasse moléculaire :279.169Colchicine-d6
CAS :Produit contrôléFormule :C22H19D6NO6Couleur et forme :SolidMasse moléculaire :405.472Desloratadine-d7 (major)
CAS :Produit contrôléApplications Labelled Desloratadine (D290250). Nonsedating-type labelled histamine H1-receptor antagonist. An active labelled metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells.
References Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000), Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000), Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001),Formule :C19H15D7ClN2Couleur et forme :NeatMasse moléculaire :320.899,10-Dehydro-19-nortestosterone
CAS :Produit contrôléApplications Gestagenic Testosterone (T155000) derivative. A steroid ligand for the cytosol androgen receptor (AR) of rat prostate.
References Ojasoo, T. et al.; J. Steroid Biochem. 27, 255 (1987); Dore, J. et al.; J. Med. Chem. 29, 54 (1986)Formule :C17H22O2Couleur et forme :NeatMasse moléculaire :258.36Vancomycin Aglycon Trifluoroacetic Acid Salt Hydrate
CAS :Produit contrôléFormule :C53H52Cl2N8O17•C2HF3O2•xH2ODegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :1143.941140218Morphine Sulfate Pentahydrate USP
CAS :Produit contrôléApplications Principle alkaloid of opium.This is a controlled substance (opiate). Analgesic (narcotic).
References Buchwald, M.E., et al.: J. Pharmacol. Exp. Ther., 71, 197 (1941), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 17, 259 (1988),Formule :C17H19NO3·H2SO4·5H2OCouleur et forme :NeatMasse moléculaire :758.83Adamantane-d16
CAS :Produit contrôléApplications Adamantane-d16 is used in the fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins. Unlabeled adamantane derivatives have been used to treat influenza, as well as serve as NMDA receptor channel blockers for a wide range of pharmaceutical application.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, C. et al.: Inorg. Chem. 45, 4769 (2012); Thomas. A. et al.: J. Neurosci., 25, 3312 (2005); Deyde, V. et al.: Exp. Rev. Mol. Diag., 9, 493 (2009);Formule :C10D16Couleur et forme :NeatMasse moléculaire :152.33Isoprocarb
CAS :Produit contrôléApplications Isoprocarb is a non-systematic carbamate insecticide. Isoprocarb functions by reversibly inactivating the enzyme acetylcholinesterase in insects.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Voss, G.: Anzeig. Schaedling., 40, 73 (1967); Metcalf, R.L. et al.: J. Agric. Food Chem., 15, 1022 (1967); Nishioka, T. et al.: Pest. Biochem. Physiol., 6, 320 (1976);Formule :C11H15NO2Couleur et forme :NeatMasse moléculaire :193.24Mieshuan
CAS :Produit contrôléApplications Mieshuan is a pesticide. It is effective against house and wild rodents, including rats and mice.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Teng, T., et al.: Zhonghua Yufang Yixue Zazhi, 13, 220 (1979); Deng, Z.: Chinese J. Preventive Medicine, 13, 220 (1979)Formule :C13H11N3O4Couleur et forme :NeatMasse moléculaire :273.24Kresoxim-methyl
CAS :Produit contrôléApplications An agricultural fungicide. Kresoxim-methyl is also useful in cannabis testing kits as a component of pesticide mixes (P698235).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gold, R.E. et al.: Pestic. Sci., 43, 250 (1995); Creemers, P. et al.: Meded. Fac. Landbouwwet. Univ. Gent, 61, 431 (1996); Gold, R.E. et al: Mod. Fungic. Antifungal Compd., 11, 79 (1996);Formule :C18H19NO4Couleur et forme :NeatMasse moléculaire :313.35Ethynyl Estradiol-13C2
CAS :Produit contrôléApplications Ethynyl Estradiol-13C2 is isotope labelled version of Ethynyl Estradiol (E685100) which can be used in biological and analytical studies of simultaneous determination of UV-filters and estrogens in aquatic invertebrates by modified Quick, Easy, Cheap, Effective, Rugged, and Safe extraction and liquid chromatography tandem mass spectrometry.
References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.Formule :C2C18H24O2Couleur et forme :White To Off-WhiteMasse moléculaire :298.39Carfentrazone Ethyl-d5
CAS :Produit contrôléFormule :C15D5H9Cl2F3N3O3Couleur et forme :NeatMasse moléculaire :417.222Des-[(E)-Methyl-3-methyoxyacrylate] Picoxystrobin
CAS :Produit contrôléApplications Des-[(E)-Methyl-3-methyoxyacrylate] Picoxystrobin is an impurity of Picoxystrobin(P437600). Picoxystrobin is a methoxyacrylate strobilurin fungicide designed for the control of wide range of cereal diseases.
References Walorczyk, S., et al.: J. Chromatograph. A., 1251, 219 (2012); Roszko, M., et al.: J. Am. OIl. Chemist. Soc., 89, 389 (2012);Formule :C14H10F3NO3Couleur et forme :NeatMasse moléculaire :297.2293Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
CAS :Produit contrôléApplications A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),Formule :C292H8H23N7O·CH4O3SCouleur et forme :NeatMasse moléculaire :597.76Triclabendazole Sulfoxide-D3
CAS :Produit contrôléApplications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.
References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)Formule :C14H6D3Cl3N2O2SCouleur et forme :NeatMasse moléculaire :378.683’-N-Desmethyl-3’-N-tosyl Azithromycin
CAS :Impurity Azithromycin EP Impurity G
Applications 3’-N-Desmethyl-3’-N-tosyl Azithromycin (Azithromycin EP Impurity G) is an Azithromycin (A927000) impurity.
References Kirst, H., et al.: Antimicrob. Agents Chemother., 33, 1419 (1989), Gandhi, R., et al.: J. Pharm. Biomed. Anal., 23, 1073 (2000),Formule :C44H76N2O14SCouleur et forme :White To Off-WhiteMasse moléculaire :889.14Sarafloxacin
CAS :Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.
References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)Formule :C20H17F2N3O3Couleur et forme :Light YellowMasse moléculaire :385.36Defluoro Dolutegravir (>85%)
CAS :Applications Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);Formule :C20H20FN3O5Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :401.394-Hydroxy Coumarin
CAS :Produit contrôléApplications 4-Hydroxy Coumarin is a plant derived antioxidant, protecting against lipid peroxidation, as well as a potential inhibitor of HIV-1 Integrase.
References Foti, M. et al.: J. Agric. F., 44, 497 (1996); J. Med. Chem., 40, 242 (1997);Formule :C9H6O3Couleur et forme :NeatMasse moléculaire :162.14Tinidazole-d5
CAS :Produit contrôléApplications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.
References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),Formule :C8H8D5N3O4SCouleur et forme :NeatMasse moléculaire :252.3Bisphenol AP-d5
CAS :Produit contrôléApplications Bisphenol AP-d5 is the isotope labelled analog of Bisphenol AP. Bisphenol AP is used to prepare triphenylmethane derivatives as inhibitors of hepatitis C virus helicase. It is a derivative of Bisphenol A (B519495) which is a monomer used for policarbonate and epoxy resins.
References Chen, C., et al.: J. Med. Chem., 52, 2716 (2009); Krishnan, A.V., et al.: Endocrinology, 132, 2279 (1993); Steinmetz, R., et al.: Trends Endocrinol. Metab., 9, 124 (1998); Petersen, H., et al.: Eur. Food Res. Technol., 216, 355 (2003)Formule :C20H13D5O2Couleur et forme :NeatMasse moléculaire :295.39Selexipag
CAS :Produit contrôléApplications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);Formule :C26H32N4O4SCouleur et forme :Light YellowMasse moléculaire :496.62Dapsone-d4
CAS :Produit contrôléApplications A labelled antibacterial used in the treatment of dermatitis herpetiformis.
References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),Formule :C12H8D4N2O2SCouleur et forme :NeatMasse moléculaire :252.33Methicillin Sodium
CAS :Produit contrôléApplications Semi-synthetic antibiotic related to Penicillin. Antimicrobial.
References Robinson, B., et al.: Biochem. Med. Metab. Biol., 48, 122 (1992), Lesnefsky, E., et al.: J. Biol. Chem., 279, 47961 (2004), Marroquin, L., et al.: Toxicol. Sci., 97, 539 (2007),Formule :C17H19N2O6S·NaCouleur et forme :NeatMasse moléculaire :402.4Pefloxacin Mesylate Dihydrate
CAS :Produit contrôléApplications Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase.
Formule :C17H20FN3O3·CH4O3S·2H2OCouleur et forme :Light YellowMasse moléculaire :465.49Naftifine-d3 Hydrochloride
CAS :Produit contrôléFormule :C21H19D3ClNCouleur et forme :NeatMasse moléculaire :326.88O,O-Dimethyl Dithiophosphate-13C2 Ammonium salt
CAS :Produit contrôléStability Hygroscopic
Applications Labelled dimethyl phosphorodithiolate derivatives used as insecticides.Formule :C2H10NO2PS2Couleur et forme :Off-WhiteMasse moléculaire :177.2Taurine-d4
CAS :Produit contrôléApplications Taurine-d4 is the isotope labelled analog of Taurine (T007850), an organic acid found in animal tissues and is a major constituent of bile. Taurine has many biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization and modulation of calcium signaling.
References Brosnan J. et al.: J. Nutrit., 136, 1636S (2006); Birdsall, T.C. et al.: Alt. Med. Rev., 3, 128 (1998); Foos, T.M. et al.: Neurochem. Res., 27, 21 (2002); Das, J. et al.: Pathophysiology, 15, 181 (2008);Formule :C22H4H3NO3SCouleur et forme :White To Off-WhiteMasse moléculaire :129.17Elvitegravir-d6 (Major)
CAS :Produit contrôléApplications A novel labelled inhibitor of human immunodeficiency virus type 1 integrase.
References Chou, T., et al.: Eur. J. Biochem., 115, 207 (1981), Baba, M., et al.: Antimicrob. Agents Chemother., 31, 1613 (1987), Craigie, R., et al.: J. Biol. Chem., 276, 23213 (2001), Chen, X., et al.: J. Mol. Biol., 380, 504 (2008),Formule :C23H17D6ClFNO5Couleur et forme :NeatMasse moléculaire :453.91Dimefline Hydrochloride
CAS :Produit contrôléApplications Dimefline is a new respiratory stimulant drug.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Edwards, J.M., et al.: J. Nat. Prod., 42, 85 (1979), Setnikar, I., et al.: Arzneim.-Forsch., 11 1109 (1961),Formule :C20H21NO3·HClCouleur et forme :NeatMasse moléculaire :359.85Valsartan N2-Glucuronide
Produit contrôléFormule :C30H37N5O9Couleur et forme :NeatMasse moléculaire :611.643(S)-10-Monohydroxy-10,11-dihydro Carbamazepine-D3 (Eslicarbazepine-D3)
CAS :Produit contrôléApplications (S)-10-Monohydroxy-10,11-dihydro Carbamazepine-D3 is a labelled analogue of (S)-10-Monohydroxy-10,11-dihydro Carbamazepine (M546510), a metabolite of Eslicarbazepine acetate (E659000) a novel central nervous system drug.
References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),Formule :C15H11D3N2O2Couleur et forme :White To Off-WhiteMasse moléculaire :257.3Lincomycin Hydrochloride
CAS :Produit contrôléApplications An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.
References Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962), Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1964), Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1994),Formule :C18H34N2O6S·HClCouleur et forme :White To Off-WhiteMasse moléculaire :443.00Chlorpyrifos Oxon
CAS :Produit contrôléStability Moisture Sensitive
Applications Chlorpyrifos Oxon is a metabolite of Chlorpyrifos (C425300) in human.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Atterberry, T., et al.: Toxicol. Appl. Pharmacol., 147, 411 (1997), Karanth, S., et al.: Toxicol. Sci., 58, 282 (2000), Barter, Z., et al.: Drug Metab. Dispos., 36, 2405 (2008),Formule :C9H11Cl3NO4PCouleur et forme :Off-WhiteMasse moléculaire :334.522'-Deoxyadenosine Monohydrate
CAS :Produit contrôléApplications 2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.
References Gordon, C., et al.: J. Med. Chem., 48, 1 (2005), Ikejiri, M., et al.: Bioorg. Med. Chem., 15, 6882 (2007),Formule :C10H13N5O3·H2OCouleur et forme :NeatMasse moléculaire :269.26Deshydroxy Azide Cyclosporin
Produit contrôléFormule :C62H110N14O12Couleur et forme :NeatMasse moléculaire :1243.62Sodium 2-((2-Ethyl-6-methylphenyl)amino)-2-oxoethanesulfonate
CAS :Produit contrôléApplications Sodium 2-((2-Ethyl-6-methylphenyl)amino)-2-oxoethanesulfonate is a pesticide metabolite found in surface water and groundwater. It is a degradation product of herbicide Acetochlor (A162500).
References Thurman, E., et al.: J. Chromatogr. A, 957, 3 (2002); Thurman, E., et al.: ACS Symp. Ser., 850, 128 (2003); Hamer, K., Freudenberger, U.: Wasser und Abfall, 13, 42 (2011); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);Formule :C11H14NO4S·NaCouleur et forme :WhiteMasse moléculaire :279.29Tenofovir Alafenamide
CAS :Produit contrôléStability Hygroscopic
Applications Tenofovir Alafenamide is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),Formule :C21H29N6O5PCouleur et forme :NeatMasse moléculaire :476.47Benzyldimethyltetradecylammonium-d7 Chloride
CAS :Produit contrôléFormule :C23H35D7ClNCouleur et forme :White To Off-WhiteMasse moléculaire :375.08Psilocybin-d4
CAS :Produit contrôléApplications Labelled Psilocybin. The major of two hallucinogenic components of Teonanacatl, the sacred mushroom of Mexico, the other component being Psilocin. Psychomimetic.Controlled substance (hallucinogen).
References Hofmann, et al.: Experientia, 14, 397 (1958), Callahan, P., et al.: J. Pharmacol. Exp. Ther., 246, 866 (1988), Appel, J., et al.: Eur. J. Pharmacol., 159, 41 (1989), Blair, J., et al.: J. Med. Chem., 43, 4701 (2000),Formule :C122H4H13N2O4PCouleur et forme :NeatMasse moléculaire :288.27Lapatinib-d7 Dihydrochloride
CAS :Produit contrôléApplications Lapatinib-d7 Dihydrochloride is a labeled Lapatinib (L175800), a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.
References Kim, T.E., et al.: Drugs, 6, 886 (2003); Wood, E.R., et al.: Cancer Res., 64, 6652 (2004); Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005)Formule :C29H21D7Cl3FN4O4SCouleur et forme :NeatMasse moléculaire :661.025-Hydroxyanthranilic Acid
CAS :Produit contrôléApplications An oral anti-diabetic drug.
References Choi, S., et al.: J. Med. Chem., 53, 3696 (2010), Fritzson, I., et al.: ChemMedChem, 5, 608 (2010), Lee-Manion, A., et al.: J. Agric. Food Chem., 57, 10619 (2009),Formule :C7H7NO3Couleur et forme :NeatMasse moléculaire :153.14Chloroquine
CAS :Applications Chloroquine used in the treatment of malaria and MDR-strains. It is a COVID19-related research product.
References Laufer, M. et al.: PLoS One., 7, e42284 (2012); Hangartner, S. et al.: Drug Test. ANal., 5, 777 (2013)Formule :C18H26ClN3Couleur et forme :White To Light BrownMasse moléculaire :319.87Dopamine 3-Beta-D-Glucuronide Sodium Salt
CAS :Produit contrôléStability Hygroscopic
Applications A metabolite of Dopamine.
References Johnson, G., et al.: Life Sci., 26, 1591 (1980), Eisenhofer, G., et al.: J. Clin. Endocrinol. Metab., 82, 3864 (1997), Strassburg, C., et al.: Biochem. J., 338, 489 (1999), Alonen, A., et al.: Drug Metab. Dispos., 33, 657 (2005),Formule :C14H18NNaO8Couleur et forme :NeatMasse moléculaire :351.28cis-trans Nepetalactone
CAS :Produit contrôléApplications cis-trans-Nepetalactone, is an organic compound, isolated from the plant catnip,which acts as a cat attractant. Nepetalactone can also be effective on some insects. It repels cockroaches and mosquitos.
References Kingsley, D, ABC Science Online, Feb 14, 2009; McElvain, S.M., et al.: J. Am.Chem.Soc, 63, 1558 (1941);Formule :C10H14O2Couleur et forme :ColourlessMasse moléculaire :166.22Thiamine hydrochloride phosphate-d3
CAS :Produit contrôléApplications Thiamine hydrochloride phosphate-d3 was used as a reagent in the redn. of cytochrome c in its reaction with thiamine and its structural analogs.
References Vovk, A. I, et al.: Russian J. of Gen. Chem. 72(11), 1808-1812. (2002)Formule :C12D3H15N4O4PS·Cl·HClCouleur et forme :NeatMasse moléculaire :420.27Bromophos-ethyl
CAS :Produit contrôléApplications Bromophos-ethyl is a phenyl organothiophosphate insecticide used in the control of flies, mosquitos and other insects. It is also used as an aracacide to control ticks.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brooke, J.P.: Int. Pest Control, 11, 18 (1969); LaBrecque, G.C. et al.: J. Econ. Entomol., 60, 760 (1967); Rueda H. et al.: Rev. Inst. Col. Agros., 3, 103 (1968)Formule :C10H12BrCl2O3PSCouleur et forme :Light YellowMasse moléculaire :394.0525-Deacetyl-23-acetyl Rifampicin (>85%)
CAS :Produit contrôléStability Hygroscopic
Applications 25-Deacetyl-23-acetyl Rifampicin is a structural isomer, and impurity, of Rifampicin (R508000), a semisynthetic antibiotic. Antibacerial (tuberculostatic).
References Furesz, et al.: Antibiot. Chemother., 16, 316 (1970), Gallo, G.G., et al.: Anal. Profiles Drug Subs., 5, 467 (1976),Formule :C43H58N4O12Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :822.94N-Desmethylcarboxy Terbinafine
CAS :Formule :C20H21NO2Couleur et forme :NeatMasse moléculaire :307.39L-Glutaryl Carnitine-d6 Chloride
CAS :Produit contrôléApplications L-Glutaryl Carnitine-d6 Chloride is the isotope labelled analog of L-Glutaryl Carnitine (G597600) and a metabolite of L-Carnitine (C184110).
References Millington, D., et al.: J. Inherit. Metab. Dis., 13, 321 (1990), Chace, D., et al.: Clin. Chem., 49, 1797 (2003),Formule :C12H16D6ClNO6Couleur et forme :NeatMasse moléculaire :317.8Oxantel Pamoate
CAS :Applications Oxantel Pamoate is used as an anthelmintic drug.
References Reitzer, L., et al.: J. Biol. Chem., 1979, 254, 2669 (1979), Huber, R., et al.: J. Neurosci. Res., 75, 441 (2004), Kim, J., et al.: Cell Metab. 3, 177 (2006), Bonnet, S., et al.: Cancer Cell., 11, 37 (2007),Formule :C23H16O6·C13H16N2OCouleur et forme :Light Yellow SolidMasse moléculaire :604.65rac 8-Hydroxy Efavirenz-d4
CAS :Produit contrôléFormule :C14H5D4ClF3NO3Couleur et forme :Off WhiteMasse moléculaire :335.7N-Demethyl Lincomycin Hydrochloride
CAS :Stability Hygroscopic
Applications N-Demethyl Lincomycin Hydrochloride is an impurity of Lincomycin (L466200), an antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.
References Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962); Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1964); Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1994)Formule :C17H32N2O6S·ClHCouleur et forme :NeatMasse moléculaire :428.97Malonic Acid-2-13C
CAS :Produit contrôléApplications Malonic Acid-2-13C is labelled Malonic Acid (M158005) which is a small bioactive molecule, that can be used in variuos reactions. It is the classic example of a competitive inhibitor, which acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.
References Weiner, N., "Malonic acid", Org. Synth.; Coll. Vol. 2: 376;Formule :C213CH4O4Couleur et forme :NeatMasse moléculaire :105.055-Hydroxy Tryptophol-d4 β-D-Glucuronide Methyl Ester
Produit contrôléFormule :C17D4H17NO8Couleur et forme :NeatMasse moléculaire :371.375Dopamine-D4 Hydrochloride
CAS :Produit contrôléApplications Labelled Dopamine. Endogenous catecholamine with α and β-adrenergic activity. Cardiotonic; antihypotensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Carter, J.E., et al.: Anal. Profiles Drug Subs., 11, 257 (1982), Dasta, J.F., et al.: Pharmacotherapy, 6, 304 (1986),Formule :C82H4H7NO2·ClHCouleur et forme :White To Light BrownMasse moléculaire :193.661-Docosanol-d45
CAS :Produit contrôléApplications 1-Docosanol-d45 is the labelled form of 1-Docosanol (D678855). 1-Docosanol works as a surfactant in cosmetics. 1-Docosanol cream has also been approved by the US Food and Drug Administration as a safe and effective topical treatment for herpes labialis.
References Noweck, K., et al.: Ullmann's Encyclopedia of Industrial Chemistry (2006); McKeough, M., et al.: Arch. Dermatol., 137, 1153 (2001)Formule :C22HD45OCouleur et forme :NeatMasse moléculaire :371.88Tiafenacil
CAS :Applications Tiafenacil is a uracil herbicide used as a pesticide for the prevention and control of plants.
References Peng, X., et al. Faming Zhuanli Shenqing, 68pp Patent 2018 CODEN:CNXXEVFormule :C19H18ClF4N3O5SCouleur et forme :Off White SolidMasse moléculaire :511.87L-erythro-Chloramphenicol
CAS :Produit contrôléApplications L-erythro-Chloramphenicol functions as a potent inhibitor of electron transport in the mitochondria in biological studies. The L-isomer can be identified from the other CAP-isomers through reversed phase and chiral liquid chromatography in combination with tandem mass spectrometric detection.
References Berendsen, B., et al.: Anal. Chim. Acta., 700, 78 (2011), Wilson, S.B., et al.: Biochim. Biophys. Acta., 292, 603 (1973)Formule :C11H12Cl2N2O5Couleur et forme :NeatMasse moléculaire :323.13N-Acetyl Desethyl Chloroquine-d4
CAS :Produit contrôléApplications A labelled Chloroquine metabolite, also an intermediate in the preparation of labelled Chloroquine It is a COVID19-related research product.
References Brown, N., et al.: J. Chromatogr., Biomed. App., 309, 426 (1984), Nord, K., et al.: Int. J. Pharm., 72, 11 (1991),Formule :C18D4H20ClN3OCouleur et forme :NeatMasse moléculaire :337.88Malonyl-L-carnitine Trifluoroacetate
Produit contrôléFormule :C10H18NO6·C2F3O2Couleur et forme :NeatMasse moléculaire :361.268L-(+)-Ampicillin
CAS :Produit contrôléFormule :C16H19N3O4SCouleur et forme :NeatMasse moléculaire :349.4Chlorhexidine-d8 Dihydrochloride
CAS :Produit contrôléApplications It is a bisbiguanide with bacteriostatic activity. Antiseptic; disinfectant.
References Davies, G.E., et al.: Br. J. Pharmacol., 9, 192 (1954), Foulkes, D.M., et al.: J. Periodontal Res., 8, 55 (1973),Formule :C22H24D8Cl4N10Couleur et forme :NeatMasse moléculaire :586.42Diethyl Oxalate-13C2
CAS :Produit contrôléApplications Isotope labelled Diethyl Oxalate is used in the synthesis of novel indole β-diketo acid derivatives as HIV-1 integrase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sechi, M., et al.: J. Med. Chem., 47, 5298 (2004);Formule :C413C2H10O4Couleur et forme :NeatMasse moléculaire :148.1325-O-Deacetyl Rifabutin
CAS :Produit contrôléFormule :C44H60N4O10Couleur et forme :NeatMasse moléculaire :804.97Famciclovir-d4
CAS :Produit contrôléApplications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral.
References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),Formule :C142H4H15N5O4Couleur et forme :Off-White To Light BeigeMasse moléculaire :325.36Propanil
CAS :Applications Propanil is a a widely used herbicide. Propanil is used mainly to control weed growth in rice fields.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kale, V. R. et al.: Poona Adric Coll. Mag., 56, 30 (1965); Oelke, E.A. et al.: Weed Sci., 16, 235 (1968); Mukhopadhyay, S.K. et al.: Ind. J. Agron., 12, 253 (1968);Formule :C9H9Cl2NOCouleur et forme :ColourlessMasse moléculaire :218.08Metolachlor ESA Sodium Salt
CAS :Applications Metolachlor ESA Sodium Salt is a salt of Metolachlor ESA (M338860), a synthetic herbicide that belongs to the chloroacetanelide. It is commonly used in agriculture.
References Mai, H., et al.: Aquat. Toxicol. 147, 48 (2014); McCarty, G. W., et al.: Sci Total Environ 473-474, 473 (2014);Formule :C15H22NO5S·NaCouleur et forme :WhiteMasse moléculaire :351.393,5-Dibromo-4-hydroxybenzoic Acid
CAS :Produit contrôléFormule :C7H4Br2O3Couleur et forme :NeatMasse moléculaire :295.913'-Azido-3'-deoxythymidine-methyl-d3 Beta-D-glucuronide, Sodium Salt
CAS :Produit contrôléApplications A deuterated metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.This compounds contains Sodium Chloride. Water content not determined.
Formule :C16D3H17N5O10·NaCouleur et forme :NeatMasse moléculaire :468.3658Mepiquat Chloride
CAS :Produit contrôléStability Hygroscopic
Applications Mepiquat Chloride is a plant growth regulator used to improve crop quality and maximize yield.
References Xiaoming, R., et al.: Field Crops Res, 149, 1-10 (2013)Formule :C7H16N·ClCouleur et forme :Off-WhiteMasse moléculaire :149.66N-(3-Aminopropyl)-n-dodecylpropane-1,3-diamine (>80%)
CAS :Formule :C18H41N3Degré de pureté :>80%Couleur et forme :ColourlessMasse moléculaire :299.54Vinpocetine-d5
CAS :Produit contrôléApplications A labelled derivative of Vincamine with vasodilating activity. Vasodilator (cerebral).
References Han, et al.: J. Biol. Chem., 274, 22337 (1999), O’Donnell, et al.: Pharmacol. Biochem. Behav., 63, 185 (1999),Formule :C22H21D5N2O2Couleur et forme :Light YellowMasse moléculaire :355.48Valproic Acid beta-D-Glucuronide
CAS :Produit contrôléStability Hygroscopic
Applications A metabolite of Valproic acid.
References Rudy, A., et al.: J. Pharmacol. Exp. Ther., 259, 1133 (1991), Nagai, K., et al.: J. Antimicrob. Chemother., 39, 295 (1997), Yamamura, N., et al.: Drug Metab. Dispos., 27, 724 (1999)Formule :C14H24O8Couleur et forme :Off-WhiteMasse moléculaire :320.34(±)-Cyhalothric Acid
CAS :Produit contrôléApplications (±)-Cyhalothric acid (CAS# 68127-59-3) is a useful research chemical compound.
Formule :C9H10ClF3O2Couleur et forme :NeatMasse moléculaire :242.62273-(4-Methylaminobutyryl)pyridine-1,2',3',4',5',6'-13C6, Dihydrochloride
CAS :Produit contrôléStability Hygroscopic
Applications An amino alcohol metabolite of nicotine, and precursor to NNK.Formule :C413C6H16Cl2N2OCouleur et forme :NeatMasse moléculaire :257.11
