Cétones

Please enquire for more information about 3-((4-(Trifluoromethoxy)phenyl)amino)cyclohex-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(2-methylpropanoyl)indane-1,3-dione is a nonsteroidal anti-inflammatory drug that inhibits the biosynthesis of prostaglandins from arachidonic acid by inhibiting cyclooxygenase. It has been shown to have biological activity in rats with carrageenan-induced inflammation and to be active against the inflammatory response in the rat paw induced by an injection of carrageenan. 2-(2-Methylpropanoyl)indane-1,3-dione also inhibits the metabolism of arachidonic acid, which may lead to a decrease in the production of prostaglandins.

Please enquire for more information about 2-methyl-1-(4-(isopropyl)phenyl)-2-(1,2,4-triazolyl)propan-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(4'-Methoxybenzoyl)indan-1,3-dione is a versatile building block that can be used to synthesize a variety of organic compounds. It is used as a reagent and as a reaction component in organic synthesis. This compound has been shown to form high quality crystals and is therefore suitable for research use. It also has potential application in the manufacture of pharmaceuticals, agrochemicals, dyes, and pigments.

Please enquire for more information about 2-((4-Methoxyphenyl)methylene)indan-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-iodo-3-(benzylamino)cyclohex-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-((4-Acetylphenyl)amino)-2-chloro-5-methylcyclohex-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(2-methylpropyl)-2-(((4-(1,2,4-triazolyl)phenyl)amino)methylene)cyclohexane-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6,7-dimethoxy-2-(4-methylphenyl)benzo[d]1,3-oxazin-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(2-Thienylmethylene)indane-1,3-dione is a cyclic ketone that is used in the production of pharmaceuticals. It belongs to the class of indanones and can be synthesized by reacting 2-thiophenecarboxylic acid with formaldehyde. This compound has been shown to have antibacterial properties in vitro.

Please enquire for more information about 2-(phenylmethylthio)-3-hydroquinazolin-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 4-Phenylcyclohexanone is used in the synthesis of CCR2 antagonists for the treatment of rheumatoid arthritis, atherosclerosis and other disease states. Also used in the preparation of coumarins via dehydrogenation and Heck coupling reactions.
References Subasinghe, N. et al.: Bioorg. Med. Chem. Lett., 23, 1063 (2013); Kim, D. et al.: Chem. Comm., 49, 4021 (2013);

Applications (Z)-1-(Benzo[b]​thiophen-​2-​yl)ethanone Oxime is an isomer of N-​(1-​Benzo[b]​thiophen-​2-​yl-​ethyl)​-​hydroxylamine a reagent used in the preparation of Zileuton, an anti-asthmatic drug.
References Guinchard, X. et al.: J. Org. Chem., 73, 2028 (2008)

Applications (5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
References Murakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981); Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987)

Applications 3,​3-​Dimethyl-​2,​4-​pentanedione is used in asymmetric hydrosilation of ketones.
References Kuwano, R., et al.: Bull. Chem. Soc. Jpn., 73, 485 (2000).

Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.

Applications 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).
References Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012)

Applications 7-Hydroxy-1-indanone (cas# 6968-35-0) is a useful research chemical.

Applications 1-(2,5-Dihydroxyphenyl)ethanone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.
References Zhao, W., et al.: Bioorg. Med. Chem., 19, 3192 (2011); Jayashree, B.S., et al.: Asian. J. Chem., 22, 1055 (2010); Benites, J., et al.: Bioorg. Med. Chem., 16, 862 (2008);

Applications 4-Hydroxyphenylacetone (cas# 770-39-8) is a useful research chemical.

Applications 2-Acetylcyclohexanone is used in the synthesis of 1-(pyridyl)ethanol derivatives that can reduce keto-esters and ketones. Also used in the synthesis of phenothiazine derivatives that can inhibit protein farnesyltransferase molecules and some that show anti-proliferative activity.
References Baciu-Atudosie, L. et al.: Bioorg. Med. Chem. Lett., 22, 6896 (2012); Kawano, S. et al.: Biosci. Biotech. Biochem., 75, 1055 (2011);

Impurity: Propafenone EP Impurity H
Applications: Flavanone (Propafenone EP Impurity H) is a Propafenone (P757500) impurity.
References Kitagawa, S., et al.: Biol. Pharm. Bull., 29, 1 (2006), Boccard, J., et al.: Eur. J. Pharm. Sci., 36, 254 (2009),

Applications Cyclopropyl Methyl Ketone is a chemical reagents used in the synthesis of PDE4 inhibitors. Also used in the synthesis of α-trifluoromethyl-amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferrer, M. et al.: Tetrahedron Lett., 54, 4821 (2013); Radchenko, D. et al.: Tetrahedron Lett., 54, 1897 (2013);

Applications 1-Cyclopropyl-1,3-butanedione is a reagent in regioselective synthesis of pyrazolylpyrazolopyrimidine derivatives in aqueous medium for antimicrobial agents.
References Novinson, T., et al.: J. Med. Chem., 17, 645 (1974); Aggarwal, R., et al.: Eur. J. Med. Chem., 46, 3038 (2011)

Applications 4-(Morpholin-4-yl)cyclohexanone is a useful synthetic intermediate. It was used to synthesize diastereomeric 3,6-diaminobicyclo[3.1.0]hexane derivatives.
References Vilsmaier, E., et al.: Synthesis, 12, 1142 (1991)

Applications 2-Isobutyrylcyclohexanone (cas# 39207-65-3) is a useful research chemical.

Applications 1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.
References Qian, J., et al.: Chem. Comm., 47, 9203 (2011); Scott, K., et al.: J. Med. Chem., 36, 1947 (1993)

Applications Dimethyl-1,3-acetonedicarboxylate is used in the preparation of optically active lycorane. It has also been substituted into bispidone derivatives for their use as ligands in PET imaging.
References Yoshizaki, H. et al.: J. Org. Chem., 60, 2016 (1995); Legdali, T. et al.: J. Org. Chem., 77, 11167 (2012);

Applications 2,4-DIMETHYL-3-HEPTANONE (cas# 18641-71-9) is a useful research chemical.

Applications 1,4-Dihydroxy-2-butanone (cas# 140-86-3) is a useful research chemical.

Applications 10-Hydroxy-2-decanone is an intermediate used in the synthesis of Monooxoisodecyl Phthalate (M547915), which is a derivative of Monoisodecyl Phthalate (M547905) which activates mouse and human Peroxisome Proliferator-Activated Receptors (PPARs).
References Bisset, K. M., et al.: Neurochem. Internatio., 59 (5), 706 (2011); Bility, M. T., et al.: Toxico. Sci., 82 (1), 170 (2004)

Applications (E)-1-(Benzo[b]​thiophen-​2-​yl)ethanone Oxime is an isomer of N-​(1-​Benzo[b]​thiophen-​2-​yl-​ethyl)​-​hydroxylamine a reagent used in the preparation of Zileuton, an anti-asthmatic drug.
References Guinchard, X. et al.: J. Org. Chem., 73, 2028 (2008)

Applications 2-Heptacosanone is a useful research chemical for organic synthesis and other chemical processes.
References Dastillung, M., et al.: J. Chem. Res. Synopses, 5, 166 (1980), Liu, Q., et al.: Advan. Mater. Res., 230, 842 (2011)

Applications 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE (cas# 2892-51-5) is a useful research chemical.

Stability Light Sensitive, Temperature Sensitive
Applications Acetoxymethyl Vinyl Ketone (cas# 38982-28-4) is a compound useful in organic synthesis.
References Zingel, V., et al.: Eur. J. Med. Chem., 25, 673 (1990), Sabourin, P., et al.: Carcinogenesis, 13, 1633 (1992),

Applications 1,3-Diphenylacetone (cas# 102-04-5) is a useful research chemical.

Applications 9-HEPTADECANONE (cas# 540-08-9) is a useful research chemical.

Applications 4'-Hydroxyflavanone (cas# 6515-37-3) could be a useful antitumor agent, specifically studied as a strong aromatase inhibitor against estrogen-dependent breast cancer.
References Kizilcan, D. S., et al.: Struct. Chem., 31, 1339 (2020)

Applications 5β-Estrane-3,17-dione is an intermediate in the synthesis of neuroactive steroids useful in the treatment of CNS-related diseases.
References PCT Int. Appl. (2015), WO 2015180679 A1 20151203;