Glycosciences

Glycosyl-donor for syntheses of N-acetylgalactosamine-glycoconjugates

Monosialyllacto-N-hexaose II is a synthetic, fluorinated oligosaccharide that is synthesized by glycosylation of the sugar monosialyllactose. Monosialyllacto-N-hexaose II has a molecular weight of 514.5 Da and is soluble in water. It can be used for applications such as custom synthesis, modification of complex carbohydrates, or click chemistry.

L-Menthylglucoside is a custom synthesis, complex carbohydrate. It has CAS number 16203-27-3 and is an Oligosaccharide and Polysaccharide. L-Menthylglucoside has been modified with methylation and glycosylation, which may be due to its Click modification. L-Menthylglucoside is a sugar that is high purity, fluorinated, and synthetic.

<p>Dideoxynojirimycin is a potent hydroxamic acid that inhibits glycosidases. It is used to treat metabolic disorders such as glycogen storage diseases. Dideoxynojirimycin has been shown to inhibit the activity of intestinal maltase, an enzyme involved in the digestion of carbohydrates. This drug also inhibits the synthesis of nucleic acids and proteins, which may be due to its ability to bind nucleophilic groups on enzymes and other biological molecules. The kinetic study showed that 1,6-dideoxynojirimycin has a stereoselective effect on mouse splenocytes, inhibiting their proliferation more effectively than 1,6-dideoxy-N-acetylneuraminic acid.</p>

<p>3-O-(a-L-fucopyranosyl)-D-galactopyranose is a glycosidic residue that is part of the β-D-Galactoside. It is an amino acid that is used to form carbohydrates. The chemical formula for 3-O-(a-L-fucopyranosyl)-D-galactopyranose is C 12 H 18 O 11 . The molecular weight of 3-O-(a-L-fucopyranosyl)-D-galactopyranose is 308.</p>

Cerebrosides are a type of complex carbohydrate that consists of a sugar molecule attached to a fatty acid. The sugar molecule is either glucose or galactose and the fatty acid is usually a long chain fatty acid. Cerebrosides are found in the brain and spinal cord and their function is not yet fully understood. Phrenosin (Cerebrosides-Phrenosin) is a high purity, custom synthesis, sugar-based glycoconjugate with Click modification, fluorination, glycosylation, synthetic, methylation, modification, oligosaccharide, monosaccharide and saccharide as its main components. It has been shown to have strong anti-inflammatory activities in animal models.

<p>N-Propanoyl mannosamine is a biochemical that belongs to the group of glycoconjugates. It is an intracellular messenger that modulates the concentration of intracellular calcium and controls the release of gamma-aminobutyric acid (GABA). N-Propanoyl mannosamine has been shown to stimulate axonal growth in cell culture, which is mediated by the polysialic acid receptor. This molecule also has a role in human osteoblast differentiation and bone formation.<br>N-Propanoyl mannosamine can be synthesized from dopamine and erythrose via a series of reactions involving acidification, oxidation, reduction, and decarboxylation. The synthesis of this molecule requires blood group O as an acceptor.</p>

2,5-Anhydro-6-azido-3,6-dideoxy-L-arabino-hexonic acid methyl ester (ADAEM) is a modified sugar that can be used as a building block for oligosaccharides and polysaccharides. ADAEM is a monosaccharide with six hydroxyl groups. This modification of the sugar molecule prevents it from participating in glycosidic bond formation. ADAEM has been shown to be resistant to enzymatic degradation and has high purity. It is also stable at high temperatures and pH ranges.

<p>2-Azido-2-deoxy-3,4-O-benzylidene-D-ribonic acid d-lactone is a glycosylation product of 2,4,6  azido  2,3,4  O  benzylidene D -ribose. It is synthesized by the reaction of 1,2  azido 2,3,4 O benzylidene D -ribose with sodium borohydride in the presence of lithium chloride. This compound possesses a number of properties including being a complex carbohydrate and methylation product. This compound is also fluorinated to give 2 azido-2 deoxy 3,4 F -benzylidene D ribonic acid d lactone. This compound can be modified for various purposes such as Click modification and polysaccharide synthesis.</p>

a-D-Glucose-1-phosphate dipotassium salt hydrate (aDG1P) is a glycogen synthesis inhibitor that inhibits the phosphorylases in the breakdown of glycogen. It also inhibits the synthesis of glycogen by inhibiting ATPase activity, which is required for the conversion of glucose to glucose 6-phosphate. The inhibition of phosphorylases and ATPase activity prevents the phosphorylation of glucose and leads to a decrease in glycogen synthesis. aDG1P has been shown to be effective in both animal models and human subjects for treating muscle disease such as Duchenne muscular dystrophy.

<p>Ulvans are structural polysaccharides present in the cell walls of green algae such as Ulva armoricana, Ulva rotondata, Ulva rigida, Ulva lacterca and Ulva pertusa. They are highly sulphated and contain rhamnose 3-sulphate, xylose, xylose 2-sulphate, glucuronic acid and iduronic acid residues.  Ulvan has several potentially valuable functionalities such as gel formation for agricultural and food applications. It has also an anticoagulant, antioxidant, antihyperlipidemic and antitumor activities that are attractive for pharmaceutical applications.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Bearberry has been used for centuries to treat various disorders of the urinary tract and prostate. The active ingredient in bearberry is a flavonol glycoside called arbutin, which is converted to hydroquinone during metabolism. As an antioxidant, hydroquinone inhibits the oxidation of LDL cholesterol and may reduce the risk of atherosclerosis. Hydroquinone has also been shown to have anti-inflammatory properties in rat liver microsomes and tissue culture, inhibiting prostaglandin synthesis by blocking cyclooxygenase activity. In vitro, bearberry extracts have been shown to inhibit bacterial growth on agar plates with pH levels from 4-7 and at concentrations between 0.1-1%. It was found that bearberry extracts were most effective against Pseudomonas aeruginosa strains, with MIC values ranging from 2-4 mg/mL. Bearberry extract was observed to be more effective than ampicillin against these strains in a chromatographic assay.</p>

<p>Phenyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a chemical compound that is a member of the class of phenyl 2-acetamido-2-deoxy-b-D-glucopyranosides. This compound has been shown to be anomeric, substituent and phenyl.</p>

<p>D-Sorbose is a monosaccharide that belongs to the group of sugar alcohols. It is a reducing sugar that can be used as an alternative for sugar in food and pharmaceutical industries. D-Sorbose has been shown to have potential industrial applications due to its high solubility, low melting point, and resistance to crystallization. The enzyme ribitol dehydrogenase from Escherichia coli was found to be active with D-sorbitol, but not with l-sorbitol. This indicates that D-sorbitol is a better substrate for this enzyme than L-sorbitol.</p>

<p>Dextran is α-(1,6)-linked α-D-glucan produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose. The main use for native dextran is as a blood plasma extender in blood transfusions. A complex of iron with dextran, known as iron dextran, is used as a source of iron to baby piglets which are often anaemic at birth.</p>

<p>Epi-inositol, also known as myo-inositol, is a member of the group of molecules known as sugar alcohols. It is a naturally occurring compound that is found in the human body and can be synthesized by the human body from glucose. Epi-inositol has been shown to have a number of biological effects, including inhibition of cell proliferation and energy metabolism in ovarian cancer cells. Epi-inositol has also been used in clinical trials for treatment of mood disorders such as depression.</p>

<p>Phenyl 2,4,6-tri-O-acetyl-3-O-allyl-β-D-thioglucopyranoside is an enantiomer that can be synthesized from the commercially available 2,4,6-triacetylphenyl boronic acid. It has been shown to have a positive effect on insulin sensitivity and uptake in plasma glucose in diabetic patients. Phenyl 2,4,6-tri-O-acetyl-3-O-allyl β D thioglucopyranoside also has a safety profile that is similar to other antidiabetic drugs. This drug has been shown to inhibit influenza virus uptake into cells by competitive inhibition of a transporter type.</p>

<p>2-Methylphenyl 4-O-benzyl-a-L-thiorhamnopyranoside is a custom synthesis that can be modified to suit the needs of the customer. It is a fluorinated oligosaccharide with a complex carbohydrate structure. The product has been shown to have high purity and will be synthesized according to customer specifications. 2-Methylphenyl 4-O-benzyl-a-L-thiorhamnopyranoside is an oligosaccharide that contains a saccharide and monosaccharide unit, which are linked together by glycosidic bonds. This product is also known as methylated thioretinamide or MTT.</p>

<p>6'-Fucosyllactose is a fucosylated form of lactose, which is a complex carbohydrate. It is a custom synthesis and has been synthesized in high purity. 6'-Fucosyllactose has CAS No. 80756-86-1 and can be found as an oligosaccharide or polysaccharide. 6'-Fucosyllactose is a monosaccharide that has been methylated and glycosylated to increase its stability. The saccharides are modified with fluorination to make it more soluble in water and to improve its solubility in organic solvents.</p>

1,2,3,5,6-Penta-O-benzoyl-D-galactofuranose is a sugar that is custom synthesized and can be modified with fluorination. This product has a CAS number of 138811-45-7 and is high purity. It can be used in glycosylation, oligosaccharide synthesis, methylation, monosaccharide synthesis and polysaccharide synthesis. It is an important building block for the modification of complex carbohydrates.

<p>(2R,3R,4R)-N-Benzyloxycarbonyl-2-hydroxymethyl-3,4-pyrrolidinediol is a custom synthesis of polysaccharide that is modified with methylation and glycosylation. It is a complex carbohydrate that has been synthesized using Click chemistry. The product is fluorinated and has high purity.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

Our company has the capability to synthesize custom complex carbohydrates. We can modify saccharides, methylate sugars, and fluorinate carbohydrates. We have a high-purity product that is synthesized in our lab. Our synthetic product is created through a process called Click chemistry.

Ivory nut mannan occurs in members of the custard apple, ebony and palm families - Ivory nut. The polysaccharide contains more than 95% mannose units linked β-(1,4) with a few a-D-galactopyranosyl units linked (1,6). It is widely used in foods, pharmaceuticals paints and explosives.

Substrate for xylosyltransferases

<p>UDP-a-D-galactose ammonium salt is a nucleotide sugar that is synthesized from uridine and D-galactose. It plays a role in cellular energy metabolism by providing substrate for the synthesis of phospholipids and glycolipids. UDP-a-D-galactose ammonium salt has been shown to be involved in the transcriptional regulation of genes encoding enzymes involved in galactose metabolism. This nucleotide sugar also has been shown to be an exogenous acceptor for various oligosaccharides, including those present on glycoproteins and glycolipids.</p>

<p>This β-glucan contain D-glucose residues with β-1,3 links and b-1-6 side branches. The frequency, location, and length of the sidechains may play a role in immunomodulation. Differences in molecular weight, shape, and structure of β-glucans can also affect the differences in biological activity. The water-soluble β-D-glucan is extracted from fruiting bodies of Piptoporus betulinus by hot aqueous extraction, followed by freeze-thawing and dialysis. Methylation analysis and NMR spectroscopy, indicated the presence of a β-D-glucan with a main chain (1,3)-linked, substituted at O-6 by single glucose residues.<br>The image was kindly provided by Dr. Chris Lawson.</p>

<p>D-myo-Inositol 1,2,3-triphosphate is a polyphosphate that is involved in phosphatidylinositol signaling. It has been shown to be involved in the regulation of cellular proliferation and differentiation. The biological function of this molecule is not well understood, but it has been shown to have a high redox potential and can have protonation at high concentrations. D-myo-Inositol 1,2,3-triphosphate binds to metal ions such as iron. This molecule has been found in mammalian cells and is believed to be a structural component of these cells.</p>

<p>Glycosylation is a process that attaches a sugar molecule to an amino acid or protein in the form of a glycosidic linkage. The attachment of the sugar molecule can be accomplished by either an enzymatic or chemical process. The type of glycosylation determines the type of linkage, which can be alpha-N-glycosidic (α-N), beta-N-glycosidic (β-N), or N-acetyl--galactosamine (NAG). Methylation is a process that changes one or more hydroxyl groups on a compound into methyl groups. It is usually performed with compounds containing alcohol groups (-OH) on their molecules. Click modification is a chemical reaction used to attach two chemical compounds together. It usually involves the use of copper(I) chloride, copper(II) chloride, and other reagents such as tetrabutylammonium bromide and potassium bromide. Click modification has been</p>

<p>2-C-(tert-Butyldimethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-L-gulono-1.4-lactone is a synthetic monosaccharide that is a modification of L-Gulono Oligosaccharide, which is a polysaccharide. 2C-(tert-Butyldimethylsilyloxy)methyl -2,3:5,6-di--O--isopropylidene--L--gulono 1.4 lactone is also known as 2C-(tert butyldimethylsilyloxy) methyl -2,3:5,6--di--O--isopropylidene--L--gulono 1.4 lactone and is used in the manufacture of saccharides and carbohydrates. It can be found in the</p>

2,3-O-Isopropylidene-L-lyxonic acid-1,4-lactone is an enantiopure compound that is a member of the glycoside family. It has been shown to inhibit the activity of glycosidases, which are enzymes that hydrolyze glycosides. 2,3-O-Isopropylidene-L-lyxonic acid-1,4-lactone has an ambiguous stereochemistry due to its carbon chains and catalytic groups. The conformational analysis of this compound reveals that it can be classified as a chiral molecule because it lacks a plane of symmetry. Crystallographic analysis has shown that 2,3-O-Isopropylidene-L-lyxonic acid-1,4-lactone adopts a dimeric form and crystallizes in an asymmetric unit cell with space group P2(1)22(1).

Bacterial exopolysaccharide from gram negative Flavobacterium spp.

Gypsogenin-3-O-glucuronide is a saponin found in the roots of Gypsophila paniculata, a plant native to China. It has been shown to have anti-inflammatory and anti-tumor activities. Gypsogenin-3-O-glucuronide has been shown to inhibit tumor growth in mice by inhibiting protein synthesis. The pentasaccharides that make up gypsogenin are present in different proportions, which leads to differences in the biological activity of this compound. This is one of the reasons why saponins have not yet been fully explored for potential use in medicine.

Tetra-guluronic acid sodium salt (1,4-linked α-L-sodium guluronotetraose) is one of a number of oligosaccharides obtained from alginate, a polysaccharide from brown seaweeds. It contains blocks of: repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences. This oligosaccharide can be released by acid hydrolysis and a number of biological activities have been discussed in a recent review.

<p>Hydroxyethyl cellulose (EHEC) is a non-ionic, water-soluble cellulose derivative produced by introduction of ethylene oxide groups to the hydroxyl groups of the cellulose backbone. Hydroxyethyl cellulose is useful as a water thickener, rheological control additive, protective colloid, binder, stabilizer, suspending agent and film former.  It is used in many industrial applications including latex paints, emulsion polymerization, petroleum, paper, pharmaceuticals, cosmetics and many other applications.</p>

<p>Monosialylated glycosphingolipid with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.</p>

The device is a leafed, solid-state, responsive device that connects with the user's skin. It measures the user's skin conductance and then produces a signal corresponding to the degree of deliquescence based on a theory that links biophilia to evolutionary circuitry. The device has been shown to be effective in combination with other devices.

<p>D-Gulose is a sugar that has been shown to have inhibitory properties on blood glucose levels. It also has insulin-like effects and can be used as an alternative to insulin injections in patients with Type 1 diabetes. D-Gulose is metabolized by the liver into 5-deoxy-D-gluconic acid and then into glucose, which can then be used for cellular energy production. The rate constant for this process was determined in experiments using rat liver slices. D-Gulose may also have potent angiogenic effects, as it increased the proliferation of pluripotent cells and caused significant increases in growth factor β1 expression. D-Gulose may also have potential anti-cancer effects, as it inhibited nitrate reductase activity in tumor cells and decreased xanthine oxidase activity.</p>

<p>This is a custom synthesis of a complex carbohydrate. The CAS number is not available and the polysaccharide has been modified. It has been glycosylated, methylated, and fluorinated. It is high purity and the sugar sequence is a custom synthesis.</p>

<p>Sodium stibogluconate is a drug that has been widely used in the treatment of leishmaniasis. It is administered as an intramuscular injection or intravenous infusion, depending on the severity of the infection. The drug targets the parasite by inhibiting its DNA topoisomerase, which disrupts DNA replication and transcription. Clinical data have shown that this drug is effective against infantum and other strains of leishmania.</p>

Neutral tetrasaccharide naturally present in human breast milk

Trehalose is a non-reducing sugar that is naturally found in some plants and animals. It is a disaccharide formed by two glucose molecules linked together with an alpha,alpha glycosidic bond. Trehalose has been shown to inhibit the growth of bacteria through the inhibition of fatty acid biosynthesis and the production of lactic acid. Trehalose has also been shown to have excipients that are used as lubricants or suspending agents in pharmaceuticals, cosmetics, food products, and animal feed. Trehalose can be used as a substitute for propionate in order to create endotoxin-free aqueous solutions.

<p>N-Acetyl-5-bromo-3-indoxyl-2,3,4-tri-O-acetyl-b-D-glucuronic acid methyl ester is a custom synthesis of an acetylated bromoglycoside. This compound is a synthetic modification of the natural product and has been shown to be effective against various bacteria. The synthesis of this compound can be achieved by the click reaction with methyl 2,2'-dithiopropionate and 5,5'-dimethoxytrityl chloride in the presence of trimethylsulfonium iodide. N—Acetyl—5—bromo—3—indoxyl—2,3,4—tri—O—acetyl--b--D--glucuronic acid methyl ester is also a monosaccharide sugar that is a carbohydrate with a high purity and modifies proteins at their active site. It also has</p>

1,2:4,6-Di-O-isopropylidene-L-sorbofuranose is a synthetic carbohydrate with a fluorinated methyl group at the C6 position. It is a monosaccharide that can be used to produce oligosaccharides and saccharides through glycosylation and methylation. The product is available in high purity and custom synthesis. This product has been modified by the click chemistry reaction.

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

Major milk pentasaccharide; reduces respiratory and gastrointestinal pathologies

<p>L-Gluconic acid calcium salt is a white crystalline powder. It is soluble in water and slightly soluble in alcohol. The structure of this compound has not been fully elucidated, but it is known to be a modification of L-gluconic acid, which is a monosaccharide. This product can be used as a biochemical reagent for the synthesis of oligosaccharides and polysaccharides.</p>

Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).

2-O-Benzoyl-3,4-O-benzylidene-D-ribono-1,5-lactone (2BBL) is a glycosylation agent that can be used for the synthesis of complex carbohydrates. It is also an effective methylating agent for glycosides and saccharides. 2BBL is fluorinated to yield 2FBL, which has been shown to be a powerful click reagent. The CAS number for 2BBL is 53478-55-0. This product is custom synthesized in high purity and can also be used as a monosaccharide in oligosaccharide synthesis.

Octacetylated chitobiose derivative

Methyl 4,6-O-benzylidene-α-D-glucopyranoside is a custom synthesis that can be used in the modification of complex carbohydrates. It is a high purity oligosaccharide with click modification and fluorination. The product is a monosaccharide sugar that has been synthesized by the process of glycosylation and hydrolysis. Methyl 4,6-O-benzylidene-α-D-glucopyranoside also has an Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity, Modification, Monosaccharide, sugar, Synthetic.

<p>Thiogalactose is a naturally occurring disaccharide that has been shown to have anti-inflammatory properties. It inhibits the production of inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), and suppresses the growth of experimental colitis in mice. Thiogalactose also denatures fatty acids and prevents 3t3-l1 preadipocytes from undergoing cellular transformation. This compound also inhibits the uptake of bovine serum albumin by macrophages, which may be due to its alkylthio group. Thiogalactose has been shown to inhibit proliferation of cultured human cells, including monocytic leukemia cells, when used at concentrations less than 10 mM.</p>

2-Azidomethyl-2-deoxy-3,4-O-isopropylidene-6-O-tert.butyldimethylsilyl-D-talono-1.5-lactone is a synthetic compound that can be customized for your specific needs. It has been shown to have high purity and the ability to undergo a variety of modifications, such as fluorination, glycosylation, methylation, and modification. It is also available in a range of sizes and types of carbohydrate, including saccharides and oligosaccharides.

<p>7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid is a synthetic glycolylneuraminic acid analogue that can be used in the treatment of bacterial infections. It is a prodrug that is converted to glycolylneuraminic acid by monoclonal antibody and other enzymes. 7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid inhibits the activity of necrosis factor (TNF) by binding to its receptor, thereby preventing TNF from binding to cells and stimulating inflammation. This compound has been shown to be effective against many bacteria including methicillin resistant Staphylococcus aureus (MRSA). Techniques used for the synthesis include high performance liquid chromatography with mass spectrometry detection and cavity ring down spectroscopy.</p>

<p>Tetra-mannuronic acid sodium salt (β-1,4-linked sodium mannuronotetraose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.  Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

5'-O-(2-Amino-2-deoxy-D-galactopyranosyl)-uridine is a fluorinated sugar that is synthesized from uridine. 5'-O-(2-Amino-2-deoxy-D-galactopyranosyl)-uridine is used as a building block in the synthesis of saccharide and oligosaccharide molecules. This product can be custom synthesized for customers. It has high purity, methylation, glycosylation and click modification.

<p>(-)-isolariciresinol-2a-O-b-D-xylopyranoside is a methylated saccharide that is used in the synthesis of complex carbohydrates. It is synthesized by reacting an aldehyde with an alcohol, and it has been modified using click chemistry. The product is purified to be at least 98% pure, and it can be custom synthesized to order. (-)-isolariciresinol-2a-O-b-D-xylopyranoside can be fluorinated for use as a fluorescent probe for various applications. It has a CAS number of 564964-92-1.</p>

<p>N- [[(2S, 3S, 4R) - 4- [(Acetyloxy) methyl] - 3- (phenylmethoxy) - 1-acetamide is a synthetic glycoside. It has been modified for fluorination and methylation. The complex carbohydrate has been synthesized with high purity and it has a CAS No..</p>

<p>D-Arabonic acid-1,4-lactone is a synthetic sugar that is modified to produce a variety of carbohydrates. This product can be used in the synthesis of oligosaccharides and monosaccharides. It is also used as a carbohydrate in the production of saccharide-based polymers, such as polysaccharides or polyols. This product has CAS number 2782-09-4 and a purity level of ≥99%.</p>

<p>(1R) -1- [(2S, 3R) - N-Benzyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic product that can be custom synthesized. It has been used in glycosylation reactions to produce oligosaccharides and monosaccharides. The chemical composition of the product is: C6H10O5 (CAS No. ).</p>

2-Acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-D-galactopyranose is a high purity, custom synthesis sugar that is modified with fluorination, glycosylation, and methylation. It has the CAS number 60283-31-0 and can be used in the modification of oligosaccharides and monosaccharides. This carbohydrate can be found in complex carbohydrates.

<p>2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl fluoride is a carbohydrate that is synthesized by the modification of D-mannose with 4,6-dichlorohexanoic acid. It is a white powder with a melting point of 170°C. 2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl fluoride can be used as a monosaccharide for glycosylation reactions or as an intermediate for custom synthesis. This product has been methylated and glycosylated before the final purification process. It has a high purity level and can be used in Click chemistry reactions.</p>

2-(3,4-Dihydroxyphenyl)ethyl b-D-glucopyranoside (2,3,4-DHPEB) is a naturally occurring phenolic acid. It has been shown to have antidepressant activity in mice and rats. 2,3,4-DHPEB inhibits the growth of Streptococcus faecalis by inhibiting fatty acid biosynthesis. This compound also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. 2,3,4-DHPEB is a ligand for PPAR receptors and activates their transcriptional activity in cells. It has been shown to have chemopreventive effects against colon cancer cell lines and is able to induce apoptosis in tumor cells.

<p>Quercetin-3-O-a-L-arabinoside is a flavonoid that has been shown to be active against human colorectal adenocarcinoma cells. Quercetin 3-O-a-L-arabinoside inhibits the proliferation of hl60 cells by inducing apoptosis and inhibiting protein synthesis. The biological properties of quercetin 3-O-a-L-arabinoside are not well understood, but it may work as an antioxidant due to its ability to scavenge free radicals. Quercetin 3-O-a-L-arabinoside has also been found to have antimicrobial activity against bacteria, fungi, and viruses. Quercetin 3 O a L arabinoside is able to inhibit the growth of various strains of Mycobacterium tuberculosis, including drug resistant strains. This compound is also shown to be effective in the treatment of platinum resistant</p>

1,2,3,6-Tetra-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,4,6 tetra-O-acetyl bDglucopyranosyl)-bDglucopyra nosyl]-bDthioglucopyranose (1) is a sugar with the chemical formula C36H62N8O24. It was first synthesized by the group of L. W. F. Heckel in 1956 and its structure was elucidated by X. Miettinen in 1957. 1 is a complex carbohydrate with a glycosidic linkage to 4 as well as an acetate ester at position 6. The compound has been modified with methyl groups at positions 2 and 3 to form 1,2,3,6 tetra O acetyl 4 O methyl 2 O methyl 3 O methyl 6 O eth

(1S) -1- [(2R, 3R,4S) -4-Hydroxymethyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol hydrochloride is a synthetic sugar that can be used in the synthesis of complex carbohydrates. The sugar is not naturally occurring and must be custom synthesized. It has been modified using fluorination, monosaccharides, and oligosaccharides to produce a glycosylation product. This modification is important for the production of polysaccharides with high purity.

<p>2-Keto-D-glucose is a substrate molecule that is used in the study of plant physiology, enzyme kinetics, and metabolic regulation. It has been shown to be an important factor in redox potential and the activation of detoxification enzymes. 2-Keto-D-glucose has also been found to be an important factor in energy metabolism, as it can be converted into pyruvate and acetyl CoA. 2-Keto-D-glucose is a common substrate molecule for many enzymes, including glycolytic enzymes, hexokinase, alcohol dehydrogenase, lactate dehydrogenase, and phosphofructokinase. 2-Keto-D-glucose has also been found to play a role in human blood serum biochemistry by acting as a substrate for erythrocyte D glucose transporter protein and glycerol kinase.</p>

<p>5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-2-C-methyl-D-ribofuranose is a 2'C methyl ribose derivative.</p>

<p>1,2,3-Tri-O-benzoyl-4,6-O-(4-methoxybenzylidene)-b-D-galactopyranose is a synthetic glycosylation product of 3,6-dideoxygalactose and 1,2,3,4,6-pentaacetyl bromide. It has been subjected to fluorination and methylation reactions. The compound has been found to be effective in the treatment of tuberculosis.</p>

D-Gluconic acid zinc salt is an inorganic compound that is used to treat deficiencies of D-gluconate. It is a salt of zinc and D-gluconic acid, which is a natural metabolite found in the human body. This compound can be used to maintain healthy levels of D-gluconate in the tissues and help control symptoms related to deficiencies. The efficiency of this method has been demonstrated by an in vitro test on human femur cells. A profile analysis showed that D-gluconic acid zinc salt was able to minimize the severity of symptoms associated with deficiencies caused by gluconate deficiency, such as tissue sensitivity and bone degradation.

<p>Methyl 4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside is a synthetically modified high purity carbohydrate. It is an oligosaccharide that can be custom synthesized to meet your requirements. This product can be used as a complex carbohydrate in the food industry.</p>

The family of sporadically occurring benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is characterized by chromosome terminal deletions, cytogenetic abnormalities, and phenotypes. The sporadically occurring benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a member of the glucosamine family. It is characterized by chromosome terminal deletions, cytogenetic abnormalities, and phenotypes.

<p>1,2,3,4-Tetra-O-pivaloyl-6-O-triisopropylsilyl-b-D-glucopyranose is a high purity custom synthesis sugar. It has been modified with fluorination and glycosylation. The CAS number for this product is 8071-79-8. Synthetic modification of the sugar to form an oligosaccharide or monosaccharide can also be performed. This product is a complex carbohydrate that contains saccharides in the form of a sugar molecule linked together by glycosidic bonds.</p>

Methyl 3,5-di-O-benzyl-D-xylofuranoside can also be used as an intermediate in the synthesis of other xylo or oligo related compounds.

2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt is a synthetic monosaccharide. It was originally synthesized by the methylation of a native oligosaccharide before being subjected to click chemistry. The resulting product is a complex carbohydrate with an aromatic ring in place of the sugar alcohol moiety. 2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt has CAS number 72983-76-7 and is soluble in water. This product is also available as a custom synthesis service and can be modified to meet your needs.

<p>Methyl 5-Azido-3-O-benzyl-5-deoxy-1,2-O-isopropylidene-D-galactofuranoside is a custom synthesis of a monosaccharide that can be fluorinated, methylated and modified with the click reaction. It is an oligosaccharide that can be saccharified by glycosylation or polysaccharided by glycosylation. It is a carbohydrate that contains a complex carbohydrate.<br>Methyl 5-Azido-3-O-benzyl-5-deoxy-1,2--O--isopropylidene--D--galactofuranoside has CAS No.</p>

<p>2,4-Dihydroxy-2-hydromethylbutanoic acid-1,4-lactone is a hydroxy anion that can be synthesized by the lactonization of 2,4-dihydroxybutanoic acid. The compound has been used to produce polymeric adsorbents for chromatographic purposes.</p>

<p>4-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-L-fucopyranose is a synthetic oligosaccharide that is synthesized from the sugar 4-O-(2,3,4,6 tetraacetyl) fucose. It can be used as a substrate for glycosylation reactions and may also be used to modify other compounds. This product can be fluorinated or methylated and has a CAS number. The purity of this product is high with no detectable impurities.</p>

<p>Benzyl-2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-a-D-glucopyranoside is an acetamido sugar molecule that has been synthesized by the reaction of benzyl alcohol with a glucoside. This compound has been shown to have potential antihistamine and anticancer activities, as well as being a potential building block for the synthesis of nucleosides. The benzyl group in this sugar molecule is vicinal and the hydroxyl groups are anilines. The conformation of this molecule is determined by lysine and arginine residues on the 3' end of the sugar chain. In order to synthesize this compound, anhydrous DMSO was used as a solvent. This chemical's properties were measured using NMR spectroscopy.</p>

<p>(2R, 3S, 4S) -3- Fluoro- 4- (hydroxymethyl) - N- methyl- 1- (phenylmethyl) -2- azetidinecarboxamide is an oligosaccharide that can be synthesized by glycosylation and fluorination. It is a high purity chemical with a custom synthesis and sugar modification. This product is synthesized by Click modification and methylation. The synthesis of this product starts with glycogen which is modified to produce monosaccharides and saccharides. These sugars are then further modified to produce the desired product. As an oligosaccharide, it has many applications including as a sugar for complex carbohydrate research.</p>

<p>Benzyl 3-amino-3-deoxy-a-D-mannopyranoside HCl is a high purity, custom synthesized, synthetic carbohydrate. It has been modified with fluorination and glycosylation. Modification of the carbohydrate is done by methylation or oligosaccharide addition. This product is a complex carbohydrate that has been synthesized from monosaccharides and saccharides. The carbohydrates are saccharide chains composed of carbon, hydrogen, and oxygen atoms in a straight or branched chain. Carbohydrates can be classified according to their number of sugar units: mono-, di-, tri-, tetra-, penta-, hexa-, hepta-, octa-, nona-.</p>

<p>Intracellular form of GlcNAc; substrate for GlcNAc-phosphate deacetylase</p>

<p>3-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a custom synthesis. It is a modification of the natural product. This compound has been fluorinated, methylated and monosaccharide modified. <br>3-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a synthetic compound that has been created by click chemistry. It contains an oligosaccharide and saccharide group. The CAS number for this compound is 5873087-81-8. 3-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is also glycosylated with sugar groups and has complex carbohydrate chains.</p>

<p>1,2,3,4-Tetra-O-benzyl-a-D-mannopyranoside is an active drug that belongs to the group of thyromimetics. It is a prodrug that is hydrolyzed in vivo to 1,2,3,4-tetra-O-acetyl-a-D-mannopyranose. This drug has been shown to be effective in treating nervous system diseases such as sclerosis and endogenous disease. The acetylation of the benzyl group on this molecule prevents it from being metabolized by enzymes that are found in the liver. The unmodified form of this drug is rapidly absorbed into the blood and reaches high concentrations quickly.</p>

<p>1,2,3,4-Tetra-O-acetyl-L-rhamnopyranose is an acetylated disaccharide that is glycosylated with mercuric triflate and glycoalkaloid acceptors. It has been shown to be a glycosylation coupling agent for theophylline in solanum species. 1,2,3,4-Tetra-O-acetyl-L-rhamnopyranose can also act as a steroidal glycoalkaloid acceptor and has been identified in Solanum species.</p>

Sialylated trisaccharide found in human urine

Methyl 2,4-di-O-methyl-α-D-glucopyranoside is a selectively protected glucose glycoside

<p>Man-9 N-glycan is a glycoprotein that is found on the surface of many viruses. It has an oligosaccharide structure, which consists of a mannose and a glucose molecule linked by an alpha-1,3-glycosidic bond. The Man-9 N-glycan can be found in human serum and is involved in lectin binding to cells. It also has antiviral activity and may be used as a model system for studying glycosidic bonds. This glycan can be broken down into smaller components by methyl glycosides or titration calorimetry, which is a technique for determining the molecular weight of substances. The Man-9 N-Glycan binds to toll-like receptor 2 (TLR2) on the surface of human cells, which activates an antibody response.</p>

<p>2-Acetamido-2,6-dideoxy-L-mannose is a deoxyhexose that is found in lipopolysaccharides from Gram-negative bacteria. 2-Acetamido-2,6-dideoxy-L-mannose is the only hexose that can be used for O antigen synthesis, which makes it an important component of LPS and O antigens. It has been sequenced in many organisms including animals, plants, and bacteria. 2-Acetamido-2,6-dideoxy-L-mannose may be involved in the translocation of bacteria across the gut epithelium into the bloodstream. The monosaccharide also plays a role in serogrouping and serotyping of bacteria.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a synthetic, fluorinated monosaccharide that belongs to the group of oligosaccharides. It is used in the synthesis of complex carbohydrates. Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a custom synthesis and can be modified with methylation or click chemistry. Methyl 2,3,4 - tri - O - pivaloyl - 6 - O - triisopropylsilyl - a - D - glucopyranoside has CAS number <br>Methyl 2,3,4 – tri – O – pivaloyl – 6 – O – triisopropylsily</p>

<p>2, 4-Anhydro-3,5-O-[(R)-benzylidene]-6-deoxy-L-mannonic acid benzamide is a synthetic sugar that is fluorinated and methylated. It has been custom synthesized and can be modified to have any desired modification. This product is in high purity and has a CAS No.</p>

<p>1,3,4,6-Tetra-O-benzyl-b-D-galactopyranoside is a custom synthesis that has been modified with methylation and fluorination. It is an oligosaccharide composed of saccharides linked by glycosidic bonds. Carbohydrates are polymers of monosaccharides, which can be classified as either simple sugars or complex carbohydrates. This product is a high purity, synthetic sugar that is suitable for use in the synthesis of complex carbohydrate polymers.</p>

<p>GT1b (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b is one of the major gangliosides in neuronal and glial membranes, it interacts with the myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishik,i 1996), as well as for viruses, a few examples include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).</p>

<p>D-ribono-1,5-lactone is a useful intermediate for the synthesis of bioactive compounds including antivirals.</p>

Click reagent for metabolic labeling of GlcNAc