Glycosciences

<p>Isorhamnetin 3-glucoside-7-rhamnoside is a type of flavonoid that is found in plants and has the chemical formula C14H12O5. It is a glycoside that is converted to its aglycone, rhamnetin, in the body. Isorhamnetin 3-glucoside-7-rhamnoside has shown potential as an antiinflammatory agent by inhibiting the ubiquitin proteasome pathway and Cox2 inhibitory activity. It also inhibits protease activity and can be used to treat inflammatory diseases such as arthritis. Isorhamnetin 3-glucoside-7-rhamnoside is synergistic with other molecules, so it can be used to prevent or treat inflammation when combined with other drugs.</p>

<p>Fully acetylated laminaritriose</p>

<p>Tridecyl beta-D-maltopyranoside is a synthetic saccharide that has been modified with fluorination and methylation. The carbohydrate can be used in the synthesis of glycosylated proteins. The product is available for custom synthesis, and it is offered in high purity form.</p>

<p>Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications.  A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.</p>

<p>Methyl 3-O-[(6-O-b-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-galactopyranoside is a white crystalline powder that is soluble in water. It can be custom synthesized to order, and has been shown to have high purity with no detectable impurities. This product can be used in Click chemistry, fluorination, glycosylation, or synthesis of complex carbohydrates. The CAS number for this product is <br>56919-86-4.</p>

<p>Methyl 2,3,4-tri-O-acetyl-6-O-tert-butyldimethylsilyl-a-D-galactopyranoside is a synthetic glycosylated peptide that contains a 6FAM reactive group for labeling. It is a high purity product with no impurities and can be used for the fluorination of saccharides. It has a CAS number of 594841-23-3 and can be custom synthesized to meet your needs. This product is typically used as an intermediate in the synthesis of polysaccharides and oligosaccharides.</p>

<p>1,6-Anhydro-2-azido-3-O-benzoyl-4-O-(2,3-di-O-benzyl-6-methyl-b-Dglucopyranosyl)-bDglucopyranose is a custom synthesis that is an oligosaccharide with a molecular weight of 672.1 Da. It is a complex carbohydrate that has been modified to include saccharides and sugars, with the addition of methylation and glycosylation. This molecule has been fluorinated for the purpose of synthesizing a synthetic molecule.</p>

<p>1,2,3,5,6-Penta-O-acetyl-D-galactofuranose is a condensation product of a 4-methylumbelliferone with the anomeric form of D-galactose. It is a white crystalline solid that can be obtained in yields up to 200 g per multigram of reactants. This compound has been shown to react with chloride ion and zinc chloride at elevated temperatures to yield the corresponding chloride or zinc salt. The crystal structure of this compound has been studied by x-ray diffraction and found to have an anomeric configuration and a space group P2(1)22(1). Carbohydrates are polyhydroxyaldehydes or polyhydroxyketones containing at least one hemiacetal or hemiketal group in their structure. The general formula for carbohydrates is (Cx(H2O)y)z where x is usually 2 or 3, y is</p>

<p>Intermediate in the synthesis of dapagliflozin</p>

<p>The 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4,6-di-O-acetyl-2 deoxy -a D galactopyranosyl Fmoc L serine tert butyl ester is a custom synthesis of an oligosaccharide. It is a saccharide with a polysaccharide that is glycosylated and has a sugar at the end. This carbohydrate can be used for Modification, Fluorination, Methylation, Monosaccharide, Synthetic purposes.</p>

<p>2,5-Anhydro-D-mannofuranose is a biologically active compound that belongs to the group of inorganic acids. It has been shown to be an inhibitor of heparin-induced thrombocytopenia. 2,5-Anhydro-D-mannofuranose inhibits platelet aggregation and prolongs bleeding time in rats by blocking glycosidic bond formation. This compound is also found as a constituent of oligosaccharides and nitrous oxide. Structural analysis has revealed that this molecule contains reactive groups and is acidic in nature. The analytical method for this compound is α1-acid glycoprotein. Monoclonal antibodies against fatty acid have been used for its detection in human serum.</p>

<p>Dabigatran 4-Acyl Glucuronide is a synthetic, fluorinated glycosylation of Dabigatran etexilate. It is modified by methylation at the 2 and 3 positions to increase its stability and half-life. This compound also has a high purity with less than 0.5% of impurities and can be custom synthesized to meet specific requirements.</p>

<p>4-Methylphenyl 2-O-acetyl-3-O-benzyl-β-D-thioglucuronide is a modification of the oligosaccharide, carbohydrate complex carbohydrate. It is synthesized by custom synthesis. This product has CAS No. and is a monosaccharide, methylation and glycosylation. The molecular weight of this product is 676.4 Da and it contains no other functional groups except for a fluorine atom in its structure.</p>

<p>A beta glycoside with an alkyne handle suitable to click chemistry</p>

<p>2-Acetamido-2,4-dideoxy-4-fluoro-D-glucopyranose (2ADFG) is a glycosaminoglycan that inhibits the biosynthesis of glycosaminoglycans by binding to the enzyme UDP-N-acetylglucosamine 2-epimerase. It is used in cellular control experiments to determine if cells are hepatocytes or not. This compound binds to glycosaminoglycans and prevents them from being synthesized, which leads to cell death. The binding of 2ADFG also results in a decrease in cellular protein synthesis and an increase in cellular lysosomal activity.</p>

<p>Heparin disaccharide III-A is a synthetic heparin that is modified with the addition of a sugar molecule. Heparin disaccharide III-A disodium salt (HDS) is a high purity, custom synthesized product and has been fluorinated to improve its stability. HDS has been shown to be an effective inhibitor of glycosylation in bacteria cells, leading to decreased production of bacterial enzymes and proteins. It also inhibits protein synthesis by preventing the methylation of ribosomes and reducing the number of saccharides available for glycosylation. The HDS molecule is composed of two sugars: N-acetylglucosamine and D-glucuronic acid. This compound also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

<p>1,2-O-Isopropylidene-D-mannitol is an alditol that is synthesized by the reaction of 1,2-O-isopropylidene glycerol with sodium sulfide. This product can be further reacted with allylamine to form a thiepane derivative. Thiepane derivatives are polyhydroxylated and have been shown to have antibacterial activity against Staphylococcus aureus, Mycobacterium tuberculosis, and Streptococcus pneumoniae.</p>

<p>4'-Hydroxypropanolol D-glucuronide D5 is a custom synthesis.</p>

<p>Please enquire for more information about 4-O-{[(6-Azidoethoxy)ethoxy]ethyl}-β-D-galactopyranosyl-2-deoxy-α-D-glucopyranose-2,1-oxazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Hyaluronic acid sodium salt - Low molecular weight 40,000 - 50,000 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-O-{[(6-Azidoethoxy)ethoxy]ethyl}-β-D-glycopyranosyl-2-deoxy-α-D glucopyranose-2,1-oxazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-O-[(2-Azidoethoxyimino)-6-deoxy-β-D-galactopyranosyl]-2-deoxy-α-D-glucopyranose-2,1-oxazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-O-{[6-(2-Azidoethoxy)ethoxy]ethyl}-β-D-mannopyranosyl-2-deoxy-α-D-glucopyranose-2,1-oxazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methoxyphenyl 2-acetamido-3,6-di-O-benzyl-4-O-[2,4-di-O-(3,6-di-O-(3,4,6-tri-O-(2,4,6,-triacetyl)-bDglucopyranosyl)-aDmannopyranosyl]-6-[2,4,-diO-(3,6,-diO-(3,4,-triacetyl)-bDgluco pyranosyl)aDmannopyranosyl]-aDmannopyranoside is a complex carbohydrate that belongs to the polysaccharides. The CAS number for this compound is 5243968. This compound has been modified by methylation and glycosylation. It is a sugar with high purity and fluorination. This compound has been synthesized by the click modification of a carbohydrate.</p>

<p>Mycophenolic acid b-D-glucuronide is a metabolite of mycophenolic acid, which is an immunosuppressant drug. The glucuronide form of mycophenolic acid is the main form found in human serum. Mycophenolic acid b-D-glucuronide has been shown to have a concentration–time curve that has a higher peak at about 3 hours and lower troughs than those for mycophenolic acid. It has also been shown to have similar effects on autoimmune diseases as its parent compound, but with fewer side effects. Mycophenolic acid b-D-glucuronide can be detected by high performance liquid chromatography (HPLC). The analytical method for this compound was developed using HPLC methods with detection by fluorescence at 254 nm and has been validated for use in human serum samples.END&gt;</p>

<p>Methyl 2,3,5-tri-O-benzoyl-b-D-arabinofuranoside is a custom synthesis of an Oligosaccharide with a molecular formula of C12H22O11. It has CAS No. 1093344-99-0 and Methylation, Glycosylation, Carbohydrate, Click modification, saccharide, sugar. This product is a high purity product that is Fluorination and Synthetic.</p>

<p>2-Amino-2-deoxy-3-O-(b-D-glucopyranuronosyl)-D-galactopyranose monohydrate is a glycoside that is found in the testes. It has inhibitory properties on oligosaccharides and can be used to study the structure of glycoconjugates. 2-Amino-2-deoxy-3-O-(b-D-glucopyranuronosyl)-D-galactopyranose monohydrate has been shown to inhibit the enzyme hydrolase, which is involved in glycoprotein synthesis. 2ADOGP has also been shown to bind to human serum albumin, an abundant protein in human blood plasma that transports lipids, hormones, and other molecules throughout the body. This binding results in a decrease in the serum concentration of 2ADOGP after administration.</p>

<p>1,3:2,4-Bis(O-benzylidene)-D-sorbitol is a hydrogenated derivative of sorbitol. It is used in fatty acid devices and as a surfactant in hydrogenation reactions. 1,3:2,4-Bis(O-benzylidene)-D-sorbitol is an acidic compound that has a low molecular mass and is soluble in water. It reacts with magnesium oxide to form the corresponding magnesium salt. This derivative is also used in silicone residue removal and as an activated organic base.</p>

<p>3-Deoxy-1,2-O-isopropylidene-5-p-toluoyl-b-L-threo pentofuranose is an Oligosaccharide with a molecular weight of 1094.00 Da. It is a synthetic sugar that is fluorinated at the 1' position and methylated at the 5' position. 3DOTF can be used as a substrate for glycosylation to produce glycans with desired terminal functionality. This product can also be modified using click chemistry to generate saccharides with novel functional groups.</p>

<p>UDP-6-deoxy-6-fluoro-D-glucose is a chemical compound that is an intermediate in glucosyltransferase and 4 epimerase reactions. UDP-6-deoxy-6-fluoro-D-glucose is used in the enzymatic synthesis of oligosaccharides, which are important to the biology of E. coli. The structure of this compound has been determined by X ray crystallography, revealing that it is a beta anomer. UDP-6 deoxy 6 fluoro D glucose also shows promiscuity with other enzymes, such as kinases, and can be used as a substrate for profiling.</p>

<p>6-O-Tert.butyldimethylsilyl - 2, 3- O- isopropylidene- 5-O tolenesulfonyl-L- gulonic acid gamma-lactone is a Carbohydrate, Modification, saccharide, Oligosaccharide, sugar. It has CAS number 713891–07–4. This product is a synthetic monosaccharide and has been custom synthesized for the customer’s specific need. The purity of this product is &gt;98% with a methylation level of &gt;99%. This product can be used in glycosylation reactions or click chemistry reactions as it contains an amino group at the C6 position.</p>

<p>6-O-Benzhydryloxybis(trimethylsilyloxy)silyl-1,2:4,5-di-O-isopropylidene-D-glycero-D-mannoheptitol is a custom synthetic oligosaccharide. It is a complex carbohydrate that can be found in the human body. It is an Oligosaccharide with CAS No. and has been modified with Methylation and Glycosylation. The saccharide content is high purity and it has been fluorinated to increase its stability. This product has been synthesized using Click chemistry for ease of use.</p>

<p>Gala1-3(Fuca1-2)Galb1-3GlcNAcb1-3Galb1-4Glc (B antigen hexasaccharide Type I)</p>

<p>D-Galactosamine (GalN) is an aldohexose (2-amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).</p>

<p>L-Idose is an aqueous solution of dextrose and anhydrous dextrose. It is a carbohydrate that provides energy to the body. L-Idose can be used to minimize the effects of certain organisms, such as bacteria, yeast, and fungi. It also helps to maintain blood glucose levels in people with diabetes by providing a source of glucose for their metabolism. L-Idose can be found in fruits and other foods that contain carbohydrates, such as breads, cereals, pastas, rice, potatoes, pasta sauces, chips, and crackers.</p>

<p>D-Altrose is an alpha-hydroxy acid that is synthesized from D-arabinose and trifluoroacetic acid. It has been shown to be a substrate for the synthesis of oligosaccharides, which are important in carbohydrate chemistry. This molecule can also be used as a reagent in the preparation of carbohydrates with a specific configuration at C2. One use of this product is in generating analytical methods that can distinguish between D-altrose and D-arabinose by monitoring the ratio of hydrogen fluoride to carbonyl group signals. D-Altrose may also be used in asymmetric synthesis, where it is a useful chiral building block for the construction of galacturonic acid derivatives.</p>

<p>D-Fructose 1-phosphate disodium salt is a high purity, custom synthesis sugar compound. It has CAS No. 71662-09-4 and Click modification. Fluorination and glycosylation are the two modifications that can be done on this product. This product is an oligosaccharide and it is a monosaccharide with saccharide as its complex carbohydrate.</p>

<p>Fucose is a 6-carbon sugar that is an essential component of the human diet. It is found in many vegetables and fruits, but it can also be produced by the body from glucose. Fucose is involved in a number of important biochemical processes, including calcium metabolism and the synthesis of galactose, l-glutamic acid, and other carbohydrates. Fucose has been shown to inhibit leukemia cells through programmed cell death and may also have a role in regulating cell proliferation.</p>

<p>3-Amino-3-deoxy-1,2:5,6-di-O-isopropylidene-a-D-glucofuranose is a synthetic, custom carbohydrate with a saccharide backbone. The modification of this molecule includes methylation and fluorination. 3-Amino-3-deoxy-1,2:5,6-di-O-isopropylidene is a modification on the saccharide backbone. This molecule is also synthesized with click chemistry to produce an amine functionality at the reducing end of the sugar. This product has high purity and can be used in research or as an intermediate for other compounds.</p>

<p>2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl bromide is a chemical reagent with the chemical formula C6H8Br4O7. It is an argon fluorochlorohydrohalide that has been used as a reagent in organic synthesis. This compound has been shown to have antibacterial activity against faecalis and other bacteria. 2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl bromide reacts with oxygen or halides to form reactive species such as tribromide or chloride. These reactive species may be responsible for the antibacterial properties of this compound.</p>

<p>Nigeran is a polysaccharide found in the cell wall of lower fungi. In certain Aspergillus and Penicillium spp., nigeran was first isolated from Penicillium expansum and Aspergillus niger (illustrated). The polysaccharide contains unbranched α-D- glucopyranose residues linked 1,3 and 1,4. Nigeran is part of the hyphal cell wall, where it can contribute up to 40 % of the cell dry weight. The polysaccharide occupies several domains or location on the hyphal wall and is highly crystalline in vivo. Deposition of nigeran is primarily at the outer surface of the hyphal wall.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>2-C-Methyl- D- arabinonic acid g- lactone is a sugar that is custom synthesized to provide high purity. It can be modified by fluorination, glycosylation, and methylation. This compound is used as a synthetic sugar in the synthesis of oligosaccharides and monosaccharides. 2-C-Methyl- D- arabinonic acid g- lactone can also be used in carbohydrate complex analysis. CAS No.: 135187-29-5</p>

<p>Methyl 2-acetamido-4-O-(2-acetamido-2,3-dideoxy-b-D-glucopyranosyl)-2,6O-(a,L-fucopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is a high purity and custom synthesis product with CAS No. 97242-84-7. This product has been fluorinated and methylated as well as glycosylated and click modified to increase its stability.</p>

<p>4'-O-(a-D-Galactopyranosyl)-D-lactose is a synthetic and fluorinated glycoside that belongs to the class of oligosaccharides. It has a molecular weight of 474.07 Da and a chemical formula of C12H23NO8. This product is available in custom synthesis in order to meet the needs of customers. It also has been modified with methylation, monosaccharide, polysaccharide, saccharide, click modification, and complex carbohydrate modifications. This product is available at high purity with CAS No. 834-02-4 and can be ordered from our website.</p>

<p>Hyacinthacine B3 is a compound that was synthesized by the Sharpless asymmetric dihydroxylation of polyhydroxylated aldehyde. It has inhibitory activities against nitrogen atoms and amines, which are important for the synthesis of proteins. The compounds with petasis amines have been shown to be effective in the treatment of influenza A virus.</p>

<p>D-Glucitol monostearate is a synthetic oligosaccharide that has been modified with fluorination, methylation, and click chemistry. It is the product of a custom synthesis and can be used as a sugar substitute or as a food additive. D-Glucitol monostearate is an off-white powder that can be used in pharmaceuticals or as food additives. It has been shown to have antiviral activity against Hepatitis C virus (HCV) and HIV replication.</p>

<p>Raloxifene 4'-D-glucuronide is a drug that is a prodrug of raloxifene, and it can be used to treat osteoporosis. The compound is metabolized by glucuronidation in the liver, and it has been found to have bioequivalence with the parent drug. Raloxifene 4'-D-glucuronide is marketed under the trade name Evista.</p>

<p>Erythrose is a sugar that is used in the biosynthesis of other sugars, such as ribose and D-erythrose. It is also an intermediate in the pentose phosphate pathway for the production of NADPH. Erythrose can be converted to erythritol by reductase enzymes, which are necessary for the synthesis of DNA. The enzyme erythrose reductase has been shown to act on wild-type strains. Erythrose reduces d-erythrose to erythritol, which inhibits polymerase chain reactions by blocking transcription and replication of DNA. Erythrose has also been shown to have inhibitory properties against Toll-like receptor signaling pathways, which may be due to its ability to reduce reactive oxygen species (ROS) and hydrogen peroxide levels in cells.</p>

<p>Probenecid is a weak acid that is rapidly converted to an active metabolite in the body. It is used as an analgesic, antipyretic, and anti-inflammatory drug. Probenecid has been shown to inhibit the formation of biliary acids in animals and humans and has been used in the treatment of chronic inflammatory conditions such as rheumatoid arthritis. The most common route of administration for this drug is orally, although it can also be given intravenously or intramuscularly. Probenecid also acts as a nonsteroidal anti-inflammatory drug (NSAID). This means that it inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes. This reduces inflammation, pain, and fever by inhibiting the production of prostaglandins that play a role in these processes.</p>