Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
939 produits trouvés pour "Antifongiques"
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CDA-IN-1
CAS :CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.Formule :C15H14N2O6Couleur et forme :SolidMasse moléculaire :318.281(Z)-Lanoconazole
(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.Formule :C14H10ClN3S2Couleur et forme :SolidMasse moléculaire :319.83Benzohydroxamic acid
CAS :Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.136Antifungal agent 13
CAS :Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83Complex III-IN-1
Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.Formule :C14H20ClNO2S2Couleur et forme :SolidMasse moléculaire :333.9AnCDA-IN-1
CAS :AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.Formule :C16H13ClN4O2Couleur et forme :SolidMasse moléculaire :328.753Complex III-IN-2
Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.Formule :C15H21ClN2O2SCouleur et forme :SolidMasse moléculaire :328.86Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Formule :C23H22BrN3O5Couleur et forme :SolidMasse moléculaire :500.34Wikstrol A
CAS :Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Formule :C30H22O10Couleur et forme :SolidMasse moléculaire :542.49Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47Antifungal agent 125
CAS :Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.Formule :C13H10BrNO4SCouleur et forme :SolidMasse moléculaire :356.192CDA-IN-2
CAS :CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.Formule :C17H16N2O7Couleur et forme :SolidMasse moléculaire :360.318Furametpyr
CAS :Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formule :C17H20ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.81A25822B
CAS :A25822B is an antifungal agent.Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66Yck2-IN-1
CAS :Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.Formule :C19H11FN4Couleur et forme :SolidMasse moléculaire :314.316Tenellin
CAS :Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Formule :C21H23NO5Couleur et forme :SolidMasse moléculaire :369.41Succinate dehydrogenase-IN-8
CAS :Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).Formule :C22H19Cl2F2N5O2Couleur et forme :SolidMasse moléculaire :494.32Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Formule :C27H21N5O2SCouleur et forme :SolidMasse moléculaire :479.55Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Formule :C19H18F4O2Couleur et forme :SolidMasse moléculaire :354.34PKR-IN-1
CAS :PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).Formule :C9HCl5N4OS2Couleur et forme :SolidMasse moléculaire :422.525
