Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
939 produits trouvés pour "Antifongiques"
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CDA-IN-4
CAS :CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.Formule :C10H9BrN4O2SCouleur et forme :SolidMasse moléculaire :329.17CDA-IN-3
CAS :CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.Formule :C16H27N3O3S2Couleur et forme :SolidMasse moléculaire :373.534Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Formule :C18H16Br2O2Couleur et forme :SolidMasse moléculaire :424.13SDH-IN-25
CAS :SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.Formule :C19H15BrCl2N2O4Couleur et forme :SolidMasse moléculaire :486.143Chitin synthase inhibitor 12
Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88ATPase-IN-5
CAS :ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.Formule :C10H10N4O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :266.28Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Formule :C24H25N3O5Couleur et forme :SolidMasse moléculaire :435.47Ethaboxam
CAS :Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.Formule :C14H16N4OS2Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :320.43HDAC-IN-87
CAS :HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.Formule :C13H7F5N4O2SCouleur et forme :SolidMasse moléculaire :378.277Chitin synthase inhibitor 6
Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47D75-4590
CAS :D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.Formule :C21H27N5Degré de pureté :98.56% - 98.85%Couleur et forme :SolidMasse moléculaire :349.47Ref: TM-T61194
5mg39,00€1mL*10mM (DMSO)46,00€10mg62,00€25mg122,00€50mg187,00€100mg269,00€200mg358,00€4-Hydroxyvoriconazole
CAS :Metabolite of voriconazole; sterol 14?-demethylase inhibitorDegré de pureté :Min. 95%1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-
CAS :Formule :C13H12F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.2708Ref: IN-DA000KX6
Produit arrêtéFumifungin
CAS :Fumifungin is a useful organic compound for research related to life sciences. The catalog number is T126406 and the CAS number is 110231-33-9.Formule :C22H41NO7Couleur et forme :SolidMasse moléculaire :431.572,7-Dihydroxynaphthalene
CAS :2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.Formule :C10H8O2Couleur et forme :SolidMasse moléculaire :160.17Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Formule :C67H127F3N10O14SDegré de pureté :99.90%Couleur et forme :SoildMasse moléculaire :1385.84Rhizocticin A
CAS :Rhizocticin A is a potential inhibitor of threonine synthase.Formule :C11H22N5O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.3Tetraconazole
CAS :Tetraconazole is an agent of pesticides.Formule :C13H11Cl2F4N3OCouleur et forme :Liquid ViscousMasse moléculaire :372.14Amphotericin A
CAS :Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.
Formule :C47H75NO17Degré de pureté :Min. 95%Masse moléculaire :926.09 g/mol
