Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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N6-Benzoyl-5'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-5'-O-DMT-adenosine is a synthetic nucleoside with antiviral activity. It is an activator of viral DNA polymerase and inhibits viral replication by inhibiting DNA synthesis in the host cell. N6-Benzoyl-5'-O-DMT-adenosine has shown anticancer activity in tumor cells, which may be due to its ability to inhibit ribonucleotide reductase and diphosphate kinase.</p>Formule :C38H35N5O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :673.73 g/molN4-Acetylcytidine
CAS :<p>N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.</p>Formule :C11H15N3O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :285.25 g/molN6-Benzoyl-3'-O-methyladenosine
CAS :<p>N6-Benzoyl-3'-O-methyladenosine is a novel modified nucleoside that has antiviral activity. It has been shown to possess high purity and high quality, and can be used as an activator for DNA synthesis. N6-Benzoyl-3'-O-methyladenosine is synthesized from 3'-O-methyladenosine with the use of phosphoramidites, ribonucleosides, or monophosphate nucleotides. The compound is CAS No. 85090-30-8 and is soluble in water.</p>Formule :C18H19N5O5Degré de pureté :Min. 96 Area-%Couleur et forme :Off-White PowderMasse moléculaire :385.37 g/molAdenosine 2',3'-cyclic monophosphate sodium
CAS :<p>Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.</p>Formule :C10H11N5NaO6PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :351.19 g/mol5-(Azidomethyl)-2’-deoxyuridine
CAS :<p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.24 g/mol2'-O-(2-Methoxyethyl)adenosine
CAS :<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside derivative that is produced by the methylation of 2'-deoxyadenosine. It is used in organic synthesis as a reagent for the alkylation of aromatic hydrocarbons and as an intermediate in the synthesis of purines. The product can be isolated with yields of 78% or greater, depending on reaction conditions and purification methods. Isomeric purity can be achieved with high purity (>99%) by recrystallization from water or ethanol. The compound has a number of physical properties that are similar to those of adenosine, including boiling point, melting point, density, and refractive index. The molecule also has two chiral centers at C2 and C4 that contribute to its isomeric nature. Adenosine is found in human connective tissue cells, where it plays a role in cell metabolism by regulating the production of RNA and DNA.</p>Formule :C13H19N5O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :325.32 g/mol2-Chloro-6-O-methylinosine
CAS :<p>2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)</p>Formule :C11H13ClN4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :316.7 g/molL-Adenosine 5'-monophosphate disodium
CAS :L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.Formule :C10H12N5Na2O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :391.18 g/mol8-Bromoinosine
CAS :<p>8-Bromoinosine is a potent chemical probe that can be used to study the molecular mechanism of cGMP-dependent protein kinase (PKG). 8-Bromoinosine reacts with the acceptor site in PKG, which is located at the base of the active site cleft. Electrons from hydrogen bond donor sites on 8-bromoadenosine are transferred to chloride ion and the resulting 8-bromoinosine chloride complex is an effective inhibitor of PKG. It has been shown that stereoselectivity plays a role in this reaction mechanism.</p>Formule :C10H11BrN4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :347.13 g/molPseudothymidine
CAS :<p>Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.</p>Formule :C10H14N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :242.23 g/mol1-(β-D-Arabinofuranosyl)cytosine 5'-monophosphate
CAS :1-(β-D-Arabinofuranosyl)cytidine 5'-monophosphate (ara-CMP) is a nucleotide derivative of cytidine, specifically a nucleotide where the ribose sugar is replaced by the arabinose sugar. It's a pyrimidine nucleotide commonly known as Cytarabine 5'-monophosphate or arabinosylcytosine 5'-monophosphate.Formule :C9H14N3O8PDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :323.2 g/molClofarabine
CAS :Clofarabine is FDA-approved for treating relapsed or refractory acute lymphoblastic leukaemia (ALL) in children after at least two other types of treatment have failedFormule :C10H11ClFN5O3Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :303.68 g/mol2-Amino-9-(β-D-ribofuranosyl)purine
CAS :<p>2-Amino-9-(β-D-ribofuranosyl)purine is a purine nucleoside consisting of the base 2-aminopurine linked via an N9-glycosidic bond to β-D-ribofuranose. As an analog of adenosine, it retains structural compatibility with nucleic acids but exhibits distinct biochemical properties, most notably intrinsic fluorescence. This makes it a valuable probe in molecular biology for studying nucleic acid structure, base pairing, and conformational changes, as its fluorescence is sensitive to local stacking interactions and environmental conditions.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/mol5'-O-DMT-N2-DMF-guanosine
CAS :<p>5'-O-DMT-N2-DMF-guanosine is a novel nucleoside that has been modified with an acetyl group on the 5'-hydroxyl group. This nucleoside has antiviral, anticancer and deoxyribonucleoside properties. It also activates diphosphate synthesis and inhibits protein synthesis. The drug is synthesized in high purity and quality, making it an excellent activator for phosphoramidites.</p>Formule :C34H36N6O7Degré de pureté :(%) Min. 85%Masse moléculaire :640.69 g/mol3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine
CAS :<p>3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. This antiviral drug is a novel synthetic nucleoside analogue that is phosphorylated to form monophosphate, which inhibits the synthesis of RNA. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine has been shown to be effective against cancer cells by inhibiting ribonucleotide reductase and DNA synthesis. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine also inhibits DNA synthesis by blocking the enzymes DNA polymerase and deoxyribonucleoside kinase.</p>Formule :C17H16N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :380.36 g/mol2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine
CAS :Intermediate in the synthesis of nelarabineFormule :C10H12ClN5O4Degré de pureté :Min. 97 Area-%Couleur et forme :Off-White PowderMasse moléculaire :301.69 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
CAS :2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a synthetic nucleoside that is used in the synthesis of RNA. It has been shown to be resistant to heat and both acidic and basic conditions. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine can be used for modifications of oligonucleotides and as a convenient sealant for the synthesis of DNA, RNA, or other nucleic acids. This product is neutralized with hydrochloric acid prior to use.Formule :C36H44N2O8SiDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :660.83 g/mol3-(3-Acetamido-3-carboxypropyl)uridine
CAS :<p>acetylated derivative from 3-(3-amino-3-carboxypropyl)uridine</p>Formule :C15H21N3O9Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :387.34 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine
CAS :N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine is a novel nucleoside analog with antiviral, anticancer and immunomodulatory activities. It has been shown to inhibit the replication of HIV-1 and to induce apoptosis in tumor cells. N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine is a phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleotides. This product is synthesized by using an automated high purity process.Formule :C38H35N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :657.73 g/mol3'-O-Methylguanosine 5'-triphosphate lithium
CAS :<p>3'-O-Methylguanosine 5'-triphosphate lithium is a nucleotide that has been synthesized and characterized. It is a biochemical regulatory molecule that is involved in the synthesis of DNA, RNA, and proteins. 3'-O-Methylguanosine 5'-triphosphate lithium binds to the guanine nucleotide binding protein G, which acts as an allosteric activator of the enzyme ribonucleotide reductase. The reconstituted enzyme system containing 3'-O-methylguanosine 5'-triphosphate lithium has demonstrated a high level of fidelity in the replication of dna templates.</p>Formule :C11H18N5O14P3•Li4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :564.97 g/mol
