Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS :N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.Formule :C38H37N3O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :663.72 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine
CAS :4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.Formule :C9H11FN6O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :286.22 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.</p>Formule :C44H49N5O7SiDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :787.97 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS :Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.Formule :C10H10BrN5O6P·NaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :430.08 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine
<p>N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine is a nucleoside analog that inhibits the activity of HIV reverse transcriptase. It is an antiviral agent that prevents the synthesis of viral DNA by competitively inhibiting the incorporation of deoxynucleotide triphosphates into viral DNA. This drug also has been shown to be effective against cytomegalovirus (CMV), herpes simplex virus, and varicella zoster virus (VZV). N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine has been synthesized with phosphoramidites and purified to high quality standards. The chemical structure includes a modified sugar moiety, an altered base moiety, and a unique phosphate group.</p>Formule :C41H41N5O8Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :731.79 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol
CAS :1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in researchFormule :C24H22N2O7Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :450.45 g/molS-Adenosyl-L-methionine disulfate tosylate
CAS :S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.Formule :C22H34N6O16S4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :766.8 g/molAdenosine-5'-O-diphosphoribose phosphate
CAS :<p>Potential metabolite of NADP+</p>Formule :C15H24N5O17P3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :639.3 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used in the synthesis of oligonucleotides. It is an activator of DNA and RNA synthesis, which has antiviral and antitumor properties. The CAS number for this compound is 81256-88-4.</p>Formule :C44H49N5O7SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :787.97 g/mol6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS :<p>6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.</p>Formule :C10H12N4O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :268.29 g/mol6-Benzylamino-9-(b-D-arabinofuranosyl)purine
CAS :<p>6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a nucleoside that is used as an activator and as an antiviral agent. It has been used in anticancer research, but it has not been found to have any significant effect against cancer cells. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a modified ribonucleoside with a boronic acid group attached to the 9 position of the purine ring. This modification leads to increased stability of the nucleotide in alkaline conditions and improved cellular uptake. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine can be phosphorylated on the 2',3' and 5' positions, forming 2',3'-diphosphate, 3'-diphosphate and 5'-triphosphate derivatives.</p>Formule :C17H19N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :357.37 g/mol8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium
CAS :8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt (8-BrAMP) is an activated analog of adenosine that binds to the cyclase enzyme and inhibits its activity. It has been shown to inhibit the production of epidermal growth factor in a model system. 8-BrAMP also blocks the synthesis of cyclic nucleotides by inhibiting cyclic nucleotide phosphodiesterase, which results in increased levels of cAMP. 8-BrAMP has been shown to inhibit HIV infection by acting as a transcription-polymerase chain inhibitor and blocking HIV mRNA synthesis. The drug also inhibits cell lysis by binding to calmodulin and β-catenin.Formule :C10H11BrN5O5PS•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :447.16 g/molN4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine
CAS :<p>N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a nucleoside monophosphate with antiviral and anticancer activity. It is used as an activator for the synthesis of oligodeoxynucleotides and may be used in the treatment of herpes zoster, AIDS, or cancer. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine has a novel structure that is modified from natural nucleosides and has been shown to have high purity.</p>Degré de pureté :Min. 97.0 Area-%Couleur et forme :PowderMasse moléculaire :445.60 g/mol5'-Deoxy-5-fluorouridine
CAS :5'-Deoxy-5-fluorouridine (5FU) is a nucleoside that is used in the treatment of cancer. It is an antimetabolite that inhibits the synthesis of DNA, RNA, and proteins by reversibly inhibiting ribonucleotide reductase. 5FU also inhibits epidermal growth factor receptor (EGFR), which leads to apoptosis in cancerous cells. The concentration–time curve for 5FU has been determined using tissue culture and hl-60 cells as biological samples. This drug has been shown to be effective against metastatic colorectal cancer when administered with other chemotherapeutic drugs.Formule :C9H11FN2O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :246.2 g/mol3'-Amino-N6-benzoyl-2',3'-dideoxy-5'-O-DMT-adenosine
<p>A valuable chemical tool for synthesizing modified oligonucleotides with specific functionalities at the 3' end, primarily used in oligonucleotide synthesis.</p>Formule :C38H36N6O5Degré de pureté :Min. 95%Masse moléculaire :656.73 g/mol5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine
CAS :5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine is a nucleoside that can be used as an activator for ribonucleosides. It has been shown to have anticancer, antiviral and antiviral activities. 5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine is synthesized by the reaction of 2'-deoxycytidine with tertbutyldimethylchlorosilane in the presence of triethylamine. The product may be purified by crystallization or chromatography.Formule :C15H26IN3O4SiDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :467.38 g/molAdenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
CAS :<p>Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt (CMPT) is a neurotrophic factor that belongs to the class of adenosine 3',5'-cyclic monophosphates. It has been shown to induce neuronal differentiation and neurite outgrowth in a model system. CMPT has also been shown to have neuroprotective effects by ameliorating the severity of Parkinson's disease symptoms. This drug has been shown to increase body mass index and IGF-I levels in vivo. CMPT has been demonstrated to inhibit tumor growth through upregulation of the cytosolic Ca2+ level, which leads to apoptosis. CMPT can be used as a pharmacological treatment for Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.</p>Formule :C10H11N5O5PS·NaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :367.25 g/mol3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxy-N2-DMF-guanosine
CAS :<p>3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxy-N2-DMF-guanosine is a phosphoramidite nucleoside that is synthesized by the reaction of 2'-deoxyguanosine and dimethyldichlorosilane. This product has anticancer activity, as it inhibits DNA synthesis and topoisomerase II activity. It also has antiviral effects, as it inhibits viral RNA synthesis. 3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxy-N2-DMF-guanosine has been shown to be more stable than its corresponding 5'-di-O-(tert-butyldimethylsilyl) analogue, with a half life of greater than 10 hours in phosphate buffered saline at 37°C.</p>Formule :C25H46N6O4Si2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :550.84 g/mol5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt
CAS :<p>5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.</p>Formule :C9H12BrN2O8PNa2Degré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :433.06 g/molAdenosine 5'-diphosphate magnesium salt
CAS :<p>Adenosine 5'-diphosphate magnesium salt (ADP-Mg) is a pharmacological agent that has inhibitory properties. It is used as a model system to study platelet function and the effect of adenosine on platelet aggregation. ADP-Mg is also used as a reagent in the study of protein synthesis and regulation. This chemical has been shown to potentiate the activity of serotonin receptors, which may contribute to its anti-inflammatory effects. Adenosine 5'-diphosphate magnesium salt also inhibits papillary muscle contractions by inhibiting Ca2+ currents, leading to an improved ejection fraction in patients with congestive heart failure.</p>Formule :C10H13N5O10P2·MgDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :449.49 g/mol
