Nucléotides
Sous-catégories appartenant à la catégorie "Nucléotides"
2638 produits trouvés pour "Nucléotides"
5'-O-Tosylthymidine
CAS :5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.
Formule :C17H20N2O7SDegré de pureté :Min. 95%Masse moléculaire :396.42 g/mol2-O-Ethylthymidine
CAS :2-O-Ethylthymidine is a nucleoside that is used to study the structure and dynamics of DNA. It can be synthesized by reacting 1-β-D-arabinofuranosylbenzene with ethylmercury acetate. 2-O-Ethylthymidine can be used in kinetic studies as it is specific for dna. It has been shown to have a conformational change, which is stabilized by the presence of an aromatic ring such as phenanthrene. This compound was also found to inhibit neuroblastoma cell growth in vitro.
Formule :C12H18N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :270.28 g/mol3′-Guanylic acid disodium
CAS :3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.
Formule :C10H14N5O8P•Na2Degré de pureté :Min. 95%Masse moléculaire :409.2 g/molAdenosine 5'-monophosphate sodium
CAS :Adenosine 5'-monophosphate sodium is a nucleotide that is involved in the energy metabolism of cells. It has been shown to inhibit oxidative injury and to activate signal pathways in response to external stimuli, such as glucose deprivation. Adenosine 5'-monophosphate sodium can be synthesized from ATP by the enzyme adenosine kinase.
Formule :C10H13N5O7P·NaDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :369.2 g/molThymidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS :Thymidine-5'-triphosphate sodium salt is a modified nucleoside with anticancer properties. It is a high-quality, high-purity ribonucleoside that can be used as an activator for the synthesis of deoxyribonucleosides and phosphoramidites. Thymidine-5'-triphosphate sodium salt has antiviral activity, which is due to its ability to inhibit viral DNA replication and transcription. This compound also has the potential to be used in the treatment of cancer cells by inhibiting DNA synthesis and cell division.Formule :C10H17N2O14P3·xNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :482.17 g/molALS-8176
CAS :ALS-8176 is a benzimidazole compound that has been shown to be effective against both wild-type and syncytial viruses. It is also active against the hepatitis B virus, which causes fulminant hepatitis in humans and death in 30% of cases. The antiviral activity of ALS-8176 was demonstrated by its ability to inhibit viral DNA synthesis and to prevent the release of new viral particles. ALS-8176 has also been shown to have a broad spectrum of activity against paramyxoviruses, including mumps, measles, and respiratory syncytial virus (RSV). This drug can be used for the treatment of influenza A and B when administered during the early stages of infection. ALS-8176 blocks the antibody response to influenza virus infection as well as monoclonal antibody binding sites on the hemagglutinin protein, preventing fusion between infected cells.Formule :C18H25ClFN3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :433.86 g/molUridine diphosphate choline (UDPC) sodium
CAS :Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.Formule :C14H25N3O12P2•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :512.3 g/molThymidine-3',5'-diphosphate disodium salt
CAS :Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Formule :C10H14N2Na2O11P2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :446.15 g/molN6-Benzyladenosine 5'-diphosphate sodium salt - 10 mM aqueous solution
CAS :N6-Benzyladenosine 5'-diphosphate sodium salt is a modified nucleoside that has a high purity, which is suitable for synthesis of DNA or RNA. It can be used in the modification of deoxyribonucleosides, ribonucleosides, and phosphoramidites. N6-Benzyladenosine 5'-diphosphate sodium salt has been shown to have anticancer effects and antiviral effects. This drug also has novel properties such as an ability to inhibit the proliferation of cancer cells.Formule :C17H21N5O10P2Degré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :517.32 g/mol2'-Deoxy-a-adenosine
CAS :2'-Deoxy-a-adenosine is a nucleoside that contains an adenine base. It has been studied for its biological properties, including its reaction with solution and its use as an antimicrobial agent. 2'-Deoxy-a-adenosine has been shown to inhibit the growth of bowel disease in mice by binding to the adenosine A3 receptor on the surface of cells. This nucleoside also binds to nuclear DNA and may be used as a pharmacological agent, but more research is needed to determine whether it would be effective against cancer cells. 2'-Deoxy-a-adenosine may also be useful as a potential drug target for the treatment of cancer due to its ability to bind with dna duplexes, which are found in all cancer cells.
Formule :C10H13N5O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :251.25 g/molent-abacavir
CAS :Ent-abacavir is a drug that belongs to the group of antiretroviral drugs. It has minimal toxicity and has been shown to be effective in long-term treatment of HIV/AIDS. Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses. This drug has been shown to have few drug interactions with other medications, although caution should be taken when using ent-abacavir with drugs that are metabolized by cytochrome P450 enzymes. Ent-abacavir is not recommended for use in patients who have chronic viral hepatitis or who have a body mass index greater than 30 kg/m2 because its pharmacokinetic properties may be altered in these individuals.Formule :C14H18N6ODegré de pureté :Min. 95%Masse moléculaire :286.33 g/molPolyoxin B
CAS :Polyoxin B is a natural product that is produced by the fungus Polyporus umbellatus. It is a synthetase inhibitor that specifically inhibits the enzyme malic acid synthetase in bacteria and fungi. Polyoxin B has been shown to have antifungal activity in vitro and to inhibit the growth of Cryptococcus neoformans, which may be due to its ability to inhibit terminal residues, such as acetate extract, bacterial strain, and synthase enzyme.Formule :C17H25N5O13Degré de pureté :Min. 70%Couleur et forme :Yellow PowderMasse moléculaire :507.41 g/molAdenosine 5'-diphosphate magnesium salt
CAS :Adenosine 5'-diphosphate magnesium salt (ADP-Mg) is a pharmacological agent that has inhibitory properties. It is used as a model system to study platelet function and the effect of adenosine on platelet aggregation. ADP-Mg is also used as a reagent in the study of protein synthesis and regulation. This chemical has been shown to potentiate the activity of serotonin receptors, which may contribute to its anti-inflammatory effects. Adenosine 5'-diphosphate magnesium salt also inhibits papillary muscle contractions by inhibiting Ca2+ currents, leading to an improved ejection fraction in patients with congestive heart failure.Formule :C10H13N5O10P2·MgDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :449.49 g/mol2',3',5'-Tri-O-acetyl-8-bromoguanosine
CAS :2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.
Formule :C16H18BrN5O8Degré de pureté :Min. 95%Couleur et forme :Off-White To Light (Or Pale) Yellow SolidMasse moléculaire :488.25 g/molAdenosine 2',3'-cyclic monophosphate
CAS :Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments. AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.Formule :C10H12N5O6PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :329.21 g/mol8-Nitroguanosine
CAS :8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.Formule :C10H12N6O7Degré de pureté :Min. 95%Masse moléculaire :328.24 g/mol2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS :2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.Formule :C21H38N2O6Si2Degré de pureté :Min. 95%Masse moléculaire :470.72 g/mol5′-O-DMT-LNA N-Bz 5-Me cytidine
CAS :5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.Formule :C39H37N3O8Degré de pureté :Min. 95%Masse moléculaire :675.73 g/mol1-b-D-Arabinofuranosyluracil 5'-monophosphate
CAS :1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.Formule :C9H13N2O9PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :324.18 g/molKinetin riboside-5'-monophosphate sodium salt
CAS :Kinetin riboside-5'-monophosphate sodium salt is a synthetic nucleotide that has been modified to include a phosphate group at the 5' position. Kinetin riboside-5'-monophosphate sodium salt is an activator of DNA synthesis and can be used for the treatment of viral infections. It also shows anticancer activity and is effective against cancer cells that are resistant to other cancer drugs.Formule :C15H16N5Na2O8P·H2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :489.29 g/mol
