Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine
CAS :2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine is a protected nucleoside derivative that can potentially be used as an intermediate in the chemical synthesis of nucleoside analogs, especially for RNA or DNA oligonucleotides. This compounds has a 2,6-Diaminopurine – a purine analog structurally similar to adenine but with an additional amino group at the 2-position and a β-D-ribofuranosyl. The 3′ and 5′ hydroxyl groups of the ribose are protected with a bulky 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS) group. This is a silyl protecting group often used to block reactivity during nucleoside synthesis.Formule :C22H40N6O5Si2Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :524.77 g/mol2'-Deoxy-2'-fluoroguanosine
CAS :<p>2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.</p>Formule :C10H12FN5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :285.23 g/molDeoxyribonucleic acid low molecular weight from salmon sperm
CAS :This low molecular DNA (deoxyribonucleic acid) from salmon sperm is a fragment that is an effective indicator of the presence of guanine in urine samples, and can be used to detect lipoperoxidation in animal hemocytes. It has also been shown to be a sublethal oxidative stress agent for human urine, which induces irreversible oxidation in the enzyme activities of signal detection. According to some recent research studies, this product is being investigated as an environmental pollutant indicator and could be used as an effective wastewater treatment method.Couleur et forme :Powder3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS :Used as a protected adenosine nucleoside in RNA synthesis. The 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group is a bulky, acid-labile protecting group specifically designed to protect the 3' and 5' hydroxyl groups of ribonucleosides during RNA oligonucleotide synthesis.Formule :C22H39N5O5Si2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :509.76 g/mol2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution
CAS :2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution, is a synthetic nucleotide analog. It has potential application in antiviral research, particularly for studying RNA-dependent RNA polymerase (RdRP) activity in RNA viruses. It mimics the natural cytidine triphosphate (CTP) but includes a 2'-C-methyl modification on the ribose sugar.Formule :C10H18N3O14P3·4C6H15NDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :901.94 g/mol2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
CAS :<p>2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine is a modified ribonucleoside that has antiviral and anticancer activity. It is synthesized by modifying the 5' hydroxyl group of the natural nucleoside, 2'-deoxyadenosine, with a 6-aminohexanoic acid to give 2'-deoxy-5'-O-(2,4,6-trimethoxybenzoyl)adenosine. This modification increases the affinity for viral DNA polymerases, leading to higher antiviral activity. The drug also has antitumor effects against human leukemia cells in culture.</p>Formule :C35H37N5O6Degré de pureté :Min. 95%Couleur et forme :Off-White To Light (Or Pale) Yellow SolidMasse moléculaire :623.72 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
CAS :<p>5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.</p>Formule :C34H38N2O9Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :618.67 g/mol9-(2',3',5'-Tri-O-benzyl-β-D-arabinofuranosyl)adenine
CAS :9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is a nucleoside that has shown anticancer and antiviral properties. It inhibits replication of DNA and RNA in cells, which may be due to its ability to inhibit the synthesis of deoxyribonucleotides and ribonucleotides. This compound is synthetically produced from 2',3',5'-tri-O-benzyl b-D-arabinofuranosyl chloride and adenine monophosphate (AMP). 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is also known as arabinoside A.Formule :C31H31N5O4Degré de pureté :Min. 95%Masse moléculaire :537.61 g/mol5'-Deoxythymidine
CAS :<p>5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.</p>Formule :C10H14N2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :226.23 g/molβ-Nicotinamide adenine dinucleotide
CAS :Nicotinamide adenine dinucleotide (NAD), is a very important and essential coenzyme formed by the union of two nucleotides covalently bond to each other by their phosphates group. NAD is present in cells either in its oxidative form or in its reduced form, NAD+ and NADH respectively. They take part in many redox reactions, carrying electrons from one molecule to another.Formule :C21H27N7O14P2Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :663.43 g/molUridine 5'-triphosphate dihydrate trisodium salt
CAS :Uridine 5'-triphosphate dihydrate trisodium salt is a nucleotide that is involved in the synthesis of RNA. This product has been used as a supplement to promote healthy eyes and skin, as well as to treat Alzheimer's disease. It has been shown to be an efficient method for the detection of active substances by hydrophilic interaction chromatography (HILIC). The HILIC method involves separating molecules based on their hydrophobic or hydrophilic properties, which are determined by the ionic strength of the solution. Uridine 5'-triphosphate dihydrate trisodium salt binds with chloride ions, which prevents it from binding with other organic compounds. The chloride ions then serve as an end point that can be detected using ultraviolet light.Formule :C9H12N2O15P3·3Na·2H2ODegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :586.12 g/molN6,3'-O-Dibenzoyl-2'-deoxyadenosine
CAS :<p>N6,3'-O-Dibenzoyl-2'-deoxyadenosine is a nucleoside that is used as a biochemical reagent in molecular biology. N6,3'-O-Dibenzoyl-2'-deoxyadenosine has been shown to be an inhibitor of the enzyme phosphodiesterase and also binds to DNA. This compound has been shown to have antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Clostridium perfringens. The lipophilicity of this compound allows it to cross the cell membrane and cleave DNA at the site of replication. N6,3'-O-Dibenzoyl-2'-deoxyadenosine is an analog of 6,4’-dihydroxybenzophenone (DBP) and can be synthesized from DBP by reacting with dibenzoyl chloride in chloroform</p>Formule :C24H21N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :459.47 g/molN4-Benzoyl-2'-deoxycytidine
CAS :N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.Formule :C16H17N3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :331.33 g/mol2-Aminoperimidine hydrochloride
CAS :2-Aminoperimidine hydrochloride is the hydrochloride salt of 2-aminoperimidine, a polycyclic aromatic heterocycle featuring a fused naphthalene–pyrimidine ring system with an amino group at the 2-position. The protonated amino group forms a stable crystalline salt with hydrochloric acid, enhancing aqueous solubility and facilitating handling in laboratory applications.Formule :C11H9N3•(HCl)xDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :219.67 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS :1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.Formule :C24H24N4O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :464.48 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
CAS :<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a new nucleoside analogue that is a phosphoramidite. It has been synthesized as an anticancer agent and antiviral drug. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine has been shown to inhibit the growth of human tumor cells in vitro, suggesting that it may have anticancer activity. This compound also inhibits viral replication by inhibiting DNA synthesis and RNA transcription in infected cells.</p>Formule :C41H43N3O9Degré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :721.79 g/molN4-Benzoyl-2'-deoxy-2'-fluorocytidine
CAS :<p>N4-Benzoyl-2'-deoxy-2'-fluorocytidine is a novel, synthetic nucleoside that has been shown to inhibit the growth of cancer cells and is being investigated as a potential anticancer drug. N4-Benzoyl-2'-deoxy-2'-fluorocytidine has also been found to be active against HIV, Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), and influenza A virus. It prevents the replication of viruses by inhibiting DNA synthesis in the host cell.</p>Formule :C16H16FN3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.31 g/molCyclic adenosine 5'-diphosphate ribose ammonium salt
CAS :<p>Cyclic Adenosine 5'-diphosphate ribose ammonium salt (CADPRAM) is a potent inhibitor of cyclic nucleotide phosphodiesterases (PDEs). CADPRAM reversibly inhibits PDEs and prevents the hydrolysis of cAMP. This inhibition can lead to an increase in cytosolic Ca2+. CADPRAM also inhibits polymerase chain reaction, which is why it cannot be used for the treatment of infectious diseases. CADPRAM has been shown to inhibit the activity of enzymes that are known to play a role in clinical pathology, such as adenylate cyclase and phosphodiesterase type 3.</p>Formule :C15H21N5O13P2·NH3Degré de pureté :Min. 95%Couleur et forme :White solid.Masse moléculaire :558.33 g/molBiotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution
CAS :Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel, synthetic and highly purified ribonucleoside phosphoramidite. It is used as an activator of nucleic acid synthesis in the preparation of DNA and RNA. Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has been shown to be effective against various types of cancer cells, including leukemic cells and breast cancer cells. The drug also inhibits the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2).Formule :C22H35N6O16P3S·xLiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :764.53 g/molThymidine-5'-triphosphate trisodium
CAS :Thymidine-5'-triphosphate or dTTP, is a nucleotide used by the cell to synthesize DNA molecules. Thymidine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of thymidine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).Formule :C10H17N2O14P3•Na3Degré de pureté :(%) Min. 90%Couleur et forme :White PowderMasse moléculaire :551.14 g/mol
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