Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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3'-Azido-3'-deoxy-L-uridine
<p>3'-Azido-3'-deoxy-L-uridine is a nucleoside that is a modified form of uridine with an azide group. It has antiviral, anticancer, and novel properties. 3'-Azido-3'-deoxy-L-uridine is synthesized from the corresponding ribonucleosides and diphosphates in high purity and quality. This compound can be used as an antiviral agent in the treatment of AIDS and herpes. It also has anticancer activity, which may be due to its ability to inhibit DNA synthesis or to bind to DNA and induce oxidative stress. 3'-Azido-3'-deoxy-L-uridine is synthesized by the enzymatic conversion of uridines with a monophosphate group at the 3' position into nucleosides with an azide group at the 3' position.</p>Formule :C9H11N5O5Degré de pureté :Min. 95%Masse moléculaire :269.21 g/mol2',5'-Dideoxyguanosine
CAS :<p>2',5'-Dideoxyguanosine is a modified nucleoside analog of guanosine, one of the four natural nucleosides found in RNA and DNA. This synthetic molecule has hydroxyl groups removed from the 2' and 5' positions of the sugar component, which alters its ability to participate in nucleic acid synthesis.</p>Formule :C10H13N5O3Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :251.25 g/molL-Cytidine
CAS :<p>L-Cytidine is a nucleoside that is found in the body, and is also used as a drug. It is a precursor to other nucleosides, such as cytidine triphosphate, which is involved in DNA synthesis and repair. L-Cytidine has been shown to be effective against HIV infection by inhibiting the activity of the enzyme ns3 protease. This inhibition prevents viral proteins from being released from cells and infecting other cells. L-Cytidine has also been shown to be an inhibitor of creatine kinase and glycosidation, two enzymes that are necessary for cell metabolism. L-Cytidine has also been shown to be reactive with halides, which may lead to unwanted side effects.</p>Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :243.22 g/mol5-Amino-2’-deoxy-2’-O-methyluridine HCl
<p>5-Amino-2’-deoxy-2’-O-methyluridine HCl is a novel nucleoside analog that has been modified with an O-methyl group at the 5′ position of the ribose moiety. This modification inhibits phosphorylation by inhibiting DNA polymerase and thus, preventing DNA synthesis. 5-Amino-2’-deoxy-2’-O-methyluridine HCl has also been shown to inhibit viral replication by inhibiting viral RNA and protein synthesis, while not affecting human RNA and protein synthesis. 5AADMUT is an activator of diphosphate metabolism in cells which may be due to its ability to inhibit enzymes involved in nucleotide metabolism (e.g., adenosine kinase).</p>Degré de pureté :Min. 95%N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine
<p>N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine is a novel nucleoside that can be used as an antiviral agent. It is a phosphoramidite and has been shown to inhibit replication of HIV, HSV, and CMV. N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine has also been shown to be an effective inhibitor of influenza A virus in vitro. This drug inhibits viral DNA synthesis by competing with natural nucleosides for incorporation into the viral DNA chain and by inhibiting viral DNA polymerase activity.</p>Formule :C38H36N6O5Degré de pureté :Min. 95%Masse moléculaire :656.75 g/mol2-Aminoadenosine
CAS :<p>2-Aminoadenosine is a synthetic nucleoside analog of adenosine in which the purine base is 2,6-diaminopurine, featuring an additional amino group at the C2 position. This modification enhances hydrogen bonding potential and alters base-pairing specificity, allowing it to form three hydrogen bonds with uracil or thymine, in contrast to adenine's two. As a result, 2-aminoadenosine has been studied for its impact on nucleic acid stability, replication fidelity, and enzymatic recognition. It has also shown potential in antiviral and anticancer research due to its ability to disrupt normal RNA and DNA metabolism.</p>Formule :C10H14N6O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :282.26 g/molUridine 5'-monophosphate
CAS :<p>Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. <br>It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.</p>Formule :C9H13N2O9PDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :324.18 g/molBBQ-650-DT CEP
CAS :<p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>Formule :C76H89N12O15PDegré de pureté :Min. 95%Masse moléculaire :1,441.6 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesis</p>Formule :C38H52N5O8PSiDegré de pureté :Min. 95%Masse moléculaire :765.93 g/mol5-Chloro-2-iodopyrimidine
CAS :<p>5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It was discovered by a team of chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry.<br>END></p>Formule :C4H2ClIN2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :240.43 g/mol3’-b-C-Methyluridine
CAS :<p>3’-b-C-Methyluridine (3′-b-CMU) is an analog of uridine. It inhibits the activity of viral and bacterial nucleases by attacking the phosphate group. 3′-b-CMU inhibits syncytial formation in cell cultures, which may be due to its ability to inhibit RNA synthesis. This drug has a hydroxyl group that can react with free radicals and may have some inhibitory effect on deoxyribonucleoside triphosphate hydrolysis. 3′-b-CMU is not widely used clinically because it is not readily available, but it is being reinvestigated for use in corynebacterium infections.</p>Degré de pureté :Min. 95%N6-Benzoyl-2',3'-isopropylideneadenosine
CAS :<p>N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.</p>Formule :C20H21N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :411.41 g/mol5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside
CAS :<p>5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside is a chemical compound that has been shown to be neurotoxic in vitro. It has significant cytotoxicity against human leukemia cells (HL60) and induces neuronal death. This drug also inhibits the production of neurotrophic factors, which are vital for the normal development of neurons. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside inhibits transcriptional regulation of genes that encode for receptors and enzymes. The compound is chemically stable and does not degrade easily by hydrolysis or oxidation. It can bind to polymerase chain reaction (PCR) primers and inhibit DNA synthesis. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside also affects cell nuclei by inhibiting DNA synthesis and enzyme activities.</p>Formule :C12H12Cl2N2O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :319.15 g/molN4-Benzoyl-5-methylcytidine
CAS :<p>N4-Benzoyl-5-methylcytidine is a labile chemical that can be uniquely prepared using biochimie. It has been shown to have anticodon activity in assays and is synthesized chemically. The nucleoside is phosphoramidite, which is methylated and reproducible. N4-Benzoyl-5-methylcytidine has been shown to inhibit the growth of cells by blocking the synthesis of purines and pyrimidines. It may also have biophysical properties that are related to its ability to bind to DNA.</p>Formule :C17H19N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :361.35 g/molTrifluorothymidine
CAS :<p>Treats herpes-associated keratitis and keratoconjunctivitis; antineoplastic</p>Formule :C10H11F3N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :296.2 g/molThymidine 5'- triphosphate-3'-monophosphate
CAS :<p>Thymidine 5'-triphosphate-3'-monophosphate is a nucleoside that is used in the synthesis of DNA. It is an activator of anticancer drugs, and has been shown to have antiviral properties. Thymidine 5'-triphosphate-3'-monophosphate can be used for the treatment of viral diseases such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and human immunodeficiency virus (HIV) infection. This nucleoside also plays a role in the prevention of tumor growth and metastasis because it inhibits DNA synthesis.</p>Formule :C10H18N2O17P4Degré de pureté :Min. 95%Masse moléculaire :562.15 g/mol2’,3’,5’-Tri-O-benzoyl-5-hydroxymethyl-2’C-methyluridine
CAS :<p>2’,3’,5’-Tri-O-benzoyl-5-hydroxymethyl-2’C-methyluridine is an analogue of 5-hydroxymethyluridine. The 2’,3’,5’-tri-O-benzoyl group is used to protect the hydroxyl group and prevent oxidation. It has been shown to inhibit replication of DNA in vitro and in vivo against human leukemia cells. This product is synthesized by phosphoramidite chemistry from 2′,3′,5′triphosphate and 5′hydroxymethyluridine. The purity of this product is >99%.<br>2’,3’,5’-Tri-O-benzoyl-5-(hydroxymethyl)uridine can be used as a nucleoside or nucleotide analog for anticancer treatments or other therapeutic purposes.</p>Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine
CAS :<p>2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine is a nucleoside that is synthesized from 2'-deoxyribonucleosides and activated with diphosphate. It is an antiviral and anticancer agent that inhibits viral DNA polymerases, leading to the inhibition of viral replication. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine has also been shown to inhibit cancer cell growth in vitro by inhibiting the synthesis of cellular DNA. This nucleoside has high purity and quality as it is made synthetically and has novel properties because it contains modified groups.</p>Formule :C35H37N5O7Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :639.71 g/mol1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide
<p>1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide is a phosphoramidite that is used for the synthesis of DNA and RNA. It has antiviral and anticancer properties. This compound binds to DNA and inhibits the activity of topoisomerase II, which leads to cell death by inhibiting the production of proteins vital for cell division. 1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide also prevents the replication of viral RNA by inhibiting reverse transcriptase.</p>Formule :C17H21N2O8Degré de pureté :Min. 95%Masse moléculaire :381.36 g/mol2'-Deoxy-2'-fluoroguanosine
CAS :<p>2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.</p>Formule :C10H12FN5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :285.23 g/mol2-Methoxycarbonyl adenosine
CAS :<p>2-Methoxycarbonyl adenosine is a modified nucleoside and nucleotide. It is an antiviral agent that has been shown to be effective against herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV). 2-Methoxycarbonyl adenosine also has anticancer activity, which may be due to its ability to inhibit DNA synthesis. This agent can also be used as a phosphoramidite for the synthesis of oligonucleotides and as a monophosphate for the synthesis of ribonucleosides. 2-Methoxycarbonyl adenosine is also available in high purity and high quality with CAS No. 70255-70-8.</p>Degré de pureté :Min. 95%2,8-Dimethyladenosine
CAS :<p>2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.</p>Formule :C12H17N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :295.29 g/mol2'-Deoxy-5-methylcytidine
CAS :<p>2'-Deoxy-5-methylcytidine is a nucleoside analogue that inhibits the synthesis of DNA. It prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine has been shown to inhibit colon cancer cells in vitro, and may be a potential biomarker for bowel disease. This drug is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.</p>Formule :C10H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :241.25 g/molThymidine-3',5'-diphosphate sodium salt
CAS :<p>Thymidine-3',5'-diphosphate sodium salt is a nucleoside that is used in the synthesis of oligonucleotides. It is an antiviral and anticancer agent. Thymidine-3',5'-diphosphate sodium salt has been shown to inhibit DNA synthesis, leading to cell death. It also has been shown to be effective against Hepatitis B virus and HIV-1.</p>Formule :C10H16N2O11P2·xNaDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :402.19 g/mol3'-Deoxythymidine
CAS :<p>3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.</p>Formule :C10H14N2O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :226.23 g/molN4-Benzoyl-2'-deoxy-a-cytidine
CAS :<p>N4-Benzoyl-2'-deoxy-a-cytidine is a novel, modified nucleoside that has shown anticancer and antiviral activity. It is synthesized by the enzymatic oxidation of 2'-deoxyadenosine with benzoyl chloride and sodium bicarbonate. N4-Benzoyl-2'-deoxy-a-cytidine has been shown to activate transcription, increase DNA synthesis, and inhibit virus replication. It also inhibits bacterial growth, but does not appear to have any effect on mammalian cells.</p>Formule :C16H17N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :331.32 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine
<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is an activator of DNA polymerase. It has been shown to be a potent inhibitor of viral replication and an anticancer agent in vitro. The compound has also been shown to inhibit the growth of tumor cells in vivo. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue that has not been previously reported.</p>Degré de pureté :Min. 95%3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine
<p>3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine is a nucleoside that can be used as an antiviral and anticancer agent. It is structurally similar to thymidine, but differs by the replacement of a hydrogen atom at position 3 with a fluorine atom. The replacement of this hydrogen atom with a fluorine atom results in the removal of hydroxyl group from the 5' carbon position on the sugar ring, which is then converted into an ester moiety. 3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine has been shown to inhibit DNA replication, RNA transcription and protein synthesis. This nucleoside also has been found to stimulate apoptosis in cancer cells by inhibiting DNA replication.</p>Formule :C18H19FN2O5Degré de pureté :Min. 95%Masse moléculaire :348.43 g/mol5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite
<p>5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer drug that inhibits viral and tumor DNA synthesis. It is a nucleoside monophosphate with antiviral and antitumor activities. The compound is synthesized by coupling a benzoyl group to 5'-O-DMT-2'-deoxyuridine 3'-phosphate, followed by the addition of a triethylammonium salt group. The phosphoramidite is then reacted with 2,4,6-trichlorophenylisocyanate to produce the final product. This product has a CAS number of 86825-34-1.</p>Formule :C25H33N4O7PDegré de pureté :Min. 95%Masse moléculaire :532.54 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
<p>Nucleoside phosphoramidite used in oligonucleotide synthesis</p>Formule :C49H58N5O10PDegré de pureté :Min. 95%Masse moléculaire :907.99 g/molAdenosine 3',5'-diphosphate disodium salt
CAS :<p>Adenosine 3',5'-diphosphate disodium salt is a nucleotide that is found in all cells and is involved in the regulation of many physiological processes, including energy metabolism and blood flow. It has inhibitory effects on platelets and calcium ion channels. Adenosine 3',5'-diphosphate disodium salt also inhibits the synthesis of prostaglandins by blocking the conversion of arachidonic acid to prostaglandin H2, which leads to an anti-inflammatory effect. Adenosine 3',5'-diphosphate disodium salt has been shown to be effective in treating primary pulmonary hypertension and bowel disease. The reaction solution can be used for polymerase chain reactions, multivariate logistic regression, or other applications.</p>Formule :C10H15N5O10P2·2NaDegré de pureté :Min. 96 Area-%Couleur et forme :White Beige PowderMasse moléculaire :473.18 g/mol2,2'-Anhydrouridine
CAS :<p>The nucleophilic opening of 2,2'-Anhydrouridine represents a novel synthetic approach for elaborating the ring of nucleosides. For example, compounds such as 2-amino-, 2-fluoro- and 2-phenylseleno-2-deoxyuridines are prepared from the nucleophilic opening of 2,2'-Anhydrouridine.Â2,2'-Anhydrouridine inhibits uridine phosphorylase, a key enzyme targeted by some antitumor drugs.</p>Formule :C9H10N2O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :226.19 g/molβ-Nicotinamide adenine dinucleotide sodium dihydrate
CAS :<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formule :C21H26N7NaO14P2•(H2O)2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :721.44 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleotide that can be used for the synthesis of DNA and RNA. It has antiviral, anticancer, and activating properties. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is synthesized by modifying cytosine with an acetyl group at the 4th position in the ribose ring, a tertiary butyldimethylsilyl group at the 2nd position on the 5' carbon atom, and a DMT group at the 5' position on the 5' carbon atom. The CAS number for this compound is 868312050.</p>Degré de pureté :Min. 95%2'-Deoxy-5-methylcytidine HCl
CAS :<p>2'-Deoxy-5-methylcytidine HCl is a cytidine derivative that is used in the synthesis of DNA. It has been shown to have anticancer and antiviral properties, as well as being a synthetic activator for RNA polymerase. The chemical name for 2'-deoxy-5-methylcytidine HCl is 5'-[(2-bromoacetyl)amino]-2'-deoxyuridine 5'-O-(1,3-dithiole-2-thiocarbonyl)-3',5' -diiodo-. It belongs to the class of deoxyribonucleosides. This product may be used in applications such as DNA synthesis, modification of DNA, and antiviral treatment.</p>Formule :C10H15N3O4·HClDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :277.7 g/mol7-Deaza-2'-deoxyadenosine
CAS :<p>7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.</p>Formule :C11H14N4O3Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :250.26 g/mol2’-Deoxyisoguanosine
CAS :<p>Incorporated in DNA/RNA hybrids and mismatch pairs to analyse helix stability</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :267.24 g/molN4-Acetyl-3'-deoxy-3'-C-methylcytidine
<p>N4-Acetyl-3'-deoxy-3'-C-methylcytidine is a novel antiviral drug that is modified from cytidine. It is an activator of the monophosphate pathway of DNA synthesis, which causes the incorporation of N4-acetyl-3'-deoxy-3'-C-methylcytidine into ribonucleosides and deoxyribonucleosides. This compound has been shown to be active against a variety of cancers, including leukemia, colon cancer, breast cancer, and prostate cancer.</p>Formule :C12H17N3O5Degré de pureté :Min. 95%Masse moléculaire :283.28 g/molN6-Benzyl-2-deoxyadenosine
<p>N6-Benzyl-2-deoxyadenosine is a modified nucleotide that can be incorporated into DNA during replication. The compound has antiviral properties and can act as an activator for the transcription of genes involved in the immune response. It is synthesized by coupling two phosphate groups to adenosine monophosphate, which is then modified with a benzyl group. This modification prevents N6-benzyl-2-deoxyadenosine from being phosphorylated and degraded to adenosine monophosphate, resulting in a stable molecule that can be incorporated into DNA.</p>Formule :C17H19N5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.36 g/mol5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
<p>5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has antiviral activity. It is an activator of the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, RNA and proteins. 5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine has shown anticancer activity in several animal models.</p>Degré de pureté :Min. 95%3-β-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS :<p>3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.</p>Formule :C15H15N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :333 g/mol5'-Ethylcarboxamidoadenosine
CAS :<p>5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.</p>Formule :C12H16N6O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :308.29 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite
CAS :<p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite is a monophosphate nucleoside analog that is synthesized in an acetylated form. It is an activator of DNA synthesis, and as such, has anticancer activity. This compound also inhibits the replication of DNA viruses and has antiviral activity against influenza virus. N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite has been shown to be effective in the prevention of HIV infection in vitro.</p>Formule :C41H49FN5O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :789.83 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
<p>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a monophosphate, which is a phosphate group that is attached to the 5' carbon on the ribose ring of RNA. This monophosphate has been modified with a 2'-O-methyl group at the 6 position of the adenosine moiety. It has also been modified with a phenoxyacetyl group at the 2 position of the adenosine moiety. The phosphoramidite backbone is an ester bond between phosphorus and nitrogen atoms, and it can be used to make DNA or RNA in vitro. This compound has anticancer properties and antiviral activities against HIV, HSV, and HBV.<br>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite has novel properties that have not</p>Formule :C49H56N7O9PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :918.01 g/mol5’-Deoxy-5’-iodo-2’-O-methyluridine
CAS :<p>5’-Deoxy-5’-iodo-2’-O-methyluridine is a nucleoside that is modified with the substitution of an iodine atom for a hydrogen atom on the 5′ carbon. It has antiviral and anticancer properties. The high purity and novel structure make this compound useful in DNA synthesis. This product can also be used as a phosphoramidite or deoxyribonucleoside building block in DNA synthesis.</p>Degré de pureté :Min. 95%3'-Amino-3'-deoxyadenosine
CAS :<p>3'-Amino-3'-deoxyadenosine, also known as spalgomycin, is a natural enediyne antibiotic with potent antibacterial and, more notably, antitumor activity observed in research settings. Its primary use is as a tool to study the mechanisms of enediyne-mediated DNA damage and as a lead compound in the search for novel anticancer therapeutics.</p>Formule :C10H14N6O3Couleur et forme :White Off-White PowderMasse moléculaire :266.26 g/mol3'-Amino-3'-deoxy-D3-thymidine
Produit contrôlé<p>3'-Amino-3'-deoxy-D3-thymidine is a novel, modified nucleoside of the deoxyribonucleosides group. It is an activator of ribonucleotide reductase and has antiviral properties. 3'-Amino-3'-deoxy-D3-thymidine is an anticancer agent that induces DNA synthesis and inhibits RNA synthesis.</p>Formule :C10H12N3O4D3Degré de pureté :Min. 95%Masse moléculaire :244.27 g/mol4'-Thioadenosine
CAS :<p>4'-Thioadenosine is a nucleoside that has been shown to inhibit the growth of leukemia cells by binding to adenosine receptors. It is also able to inhibit the activity of the mammalian phosphodiesterase PDE4, which is responsible for hydrolyzing cAMP. The cellular effects of 4'-thioadenosine can be seen in HL-60 human cells, and this drug has also shown promising results in animal models of kidney fibrosis and liver cirrhosis. 4'-Thioadenosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>Formule :C10H13N5O3SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :283.31 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
CAS :<p>2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.</p>Degré de pureté :Min. 95%2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine
<p>2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Degré de pureté :Min. 95%
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