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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 7-Iodo-7-deaza-2'-C-methylguanosine


    <p>7-Iodo-7-deaza-2'-C-methylguanosine has antiviral activity and is used as a building block in the synthesis of DNA and RNA molecules. 7-Iodo-7-deaza-2'-C-methylguanosine is a novel synthetic nucleoside that has anticancer properties and is used for the treatment of different types of cancer. It is also used for the prevention of viral infections, such as influenza. This product has high purity and is available in its phosphate or monophosphate form.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NI14082

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  • 3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O-trityluridine

    CAS :
    <p>3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O-trityluridine is an antiviral nucleoside that can inhibit the synthesis of DNA in cells. It has been shown to be active against Hepatitis B and Human Immunodeficiency Virus (HIV). This drug has also been shown to have anticancer properties. 3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O -trityluridine is a novel nucleoside modified at the 5′ position with a trityl group and with an amino group at the 3′ position. 3′ b -amino 2 ′,3 ′ -dideoxy 5 ′ -methyl 5 ′ -O trityl uridine is water soluble and stable in acid conditions.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162921

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  • N1-Methylpseudouridine-5'-triphosphate trisodium


    <p>Please enquire for more information about N1-Methylpseudouridine-5'-triphosphate trisodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C10H14N2Na3O15P3
    Masse moléculaire :564.11 g/mol

    Ref: 3D-M-9580

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  • 7-Deazaguanosine

    CAS :
    <p>7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses.</p>
    Formule :C11H14N4O5
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White Powder
    Masse moléculaire :282.26 g/mol

    Ref: 3D-ND05752

    25mg
    234,00€
    50mg
    355,00€
    100mg
    501,00€
    250mg
    798,00€
    500mg
    1.179,00€
  • 5-(Azidomethyl)-2’-deoxyuridine

    CAS :
    <p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>
    Formule :C10H13N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :283.24 g/mol

    Ref: 3D-NA162993

    1g
    4.915,00€
    25mg
    428,00€
    50mg
    635,00€
    100mg
    1.020,00€
    250mg
    2.102,00€
  • 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine

    CAS :
    <p>2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162875

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  • 8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt

    CAS :
    <p>Activator of cGMP-dependent protein kinases</p>
    Formule :C10H10BrN5NaO7P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :446.08 g/mol

    Ref: 3D-NB07973

    1g
    1.366,00€
    25mg
    267,00€
    50mg
    382,00€
    100mg
    509,00€
    250mg
    807,00€
  • 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine


    <p>2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analog that has been shown to have anticancer, antiviral and antiretroviral activities. It binds to the ribonucleotide reductase enzyme and inhibits deoxyribonucleoside synthesis in cells. 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is also an activator of ribonucleotide reductase. This drug has been shown to be effective in treating leukemia, lymphoma, and breast cancer cells.</p>
    Formule :C23H21N3O5
    Degré de pureté :Min. 95%
    Masse moléculaire :419.44 g/mol

    Ref: 3D-NA09232

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  • 6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside which has been shown to be active against HIV and other viruses. It is a phosphoramidate of 2'-deoxyadenosine 5'-monophosphate with an amino group at the 2' position. This compound inhibits the replication of DNA by binding to the enzyme reverse transcriptase and prevents the synthesis of viral DNA. 6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine also has anticancer properties, as it inhibits cell proliferation in vitro and in vivo.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162981

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  • 5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine


    <p>5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is a deoxyribonucleoside that has antiviral, anticancer, and novel properties. It has a CAS No. of 49811-91-7 and a molecular weight of 290.5 g/mol. The chemical formula for 5'-0-p-anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is C12H14FN2O9. It is synthesized by reacting 2,6-(1H,1'H)-benzoxazinones with 3' -deoxycytidines in the presence of phosphoric acid and anhydrous zinc chloride in methanol at room temperature to form the 5'-0 p anisoyl derivative, which is then reacted with</p>
    Formule :C24H22FN3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :467.45 g/mol

    Ref: 3D-NA08685

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  • 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine

    CAS :
    <p>5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine is a novel nucleoside that has antiviral and anticancer properties. It is an activator of the monophosphate phosphoramidites and has been shown to inhibit the growth of cancer cells in vitro. 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine is also able to inhibit viral replication by terminating cellular DNA synthesis at the level of RNA polymerase II. This results in the synthesis of defective viral genomes that are unable to produce new viruses, thereby preventing viral spread.</p>
    Formule :C19H19FN2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :406.36 g/mol

    Ref: 3D-NT144914

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  • 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine

    CAS :
    <p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine is a synthetic nucleoside analog that has been shown to be an activator of DNA synthesis in mammalian cells. It has antiviral, anticancer, and antibiotic properties due to its ability to inhibit the growth of a variety of cancer cells. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine also inhibits viral replication by interfering with the replication machinery. This nucleoside analog is a modified form of 6MP and has high purity and quality.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND162823

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  • 2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine

    CAS :
    <p>2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine is a novel nucleoside that has been modified to be phosphorylated on the 5' position. This modification provides the molecule with more stability in vivo and increases its anticancer potential. The synthesis of 2'-amino-2'-deoxy-5'-O-DMT-5 methyluridine is carried out by the conversion of 5'-O-(4,4'-dimethoxytrityl)-N,N-diisopropylphosphoramidite to 5'-O-(4,4'-dimethoxytrityl)-2',3',6'-triisopropylbenzoylphosphate. This compound can also inhibit viral replication by inhibiting dsRNA synthesis and is used to treat patients with chronic hepatitis B virus infection.<br>The molecule has high purity and high quality.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA144650

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  • 7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl

    CAS :
    <p>7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.</p>
    Formule :C16H16F3N5O3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :383.33 g/mol

    Ref: 3D-ND156888

    10mg
    135,00€
    25mg
    201,00€
    50mg
    286,00€
    100mg
    449,00€
    250mg
    787,00€
  • 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D- ribo-hex-5-enofu ranosyl]uracil


    <p>5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB162929

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  • 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite


    <p>2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite is a novel, modified nucleoside. It is a monophosphate and can be used as antiviral, activator or diphosphate. It has been shown to inhibit the growth of cancer cells in vitro. 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite also has activity against bacterial and viral pathogens and can be used for the synthesis of DNA, RNA, and other oligonucleotide compounds. This product is of high quality and purity with CAS No., Antiviral, Activator, diphosphate, Synthetic, Ribonuclesides, Deoxyribonucleosides.</p>
    Formule :C37H42FN4O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :688.74 g/mol

    Ref: 3D-PD09190

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  • 2'-O-tert-Butyldimethylsilyladenosine

    CAS :
    <p>2'-O-tert-Butyldimethylsilyladenosine is a novel nucleoside. It is an anti-cancer and antiviral agent that is synthesized from ribonucleosides by the phosphoramidite method. 2'-O-tert-Butyldimethylsilyladenosine has been shown to be active against DNA polymerases, RNA polymerases, and enveloped viruses. This drug also inhibits cell proliferation in a variety of human tumor cells in vitro. 2'-O-tert-Butyldimethylsilyladenosine has been shown to exhibit anticancer activity by interfering with DNA synthesis and preventing the replication of damaged cells.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB15545

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  • N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite


    <p>N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits the growth of cancer cells. It is a modified nucleoside that has been used to synthesize phosphorothioate oligonucleotides and has been shown to have antiviral and anticancer activities. This compound binds with high affinity to the active site of DNA polymerase, preventing incorporation of ribonucleosides into DNA. N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is an activator that increases the rate of deoxyribonucleotide synthesis by DNA polymerase.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-PD64043

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  • 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine

    CAS :
    <p>2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a novel phosphoramidite nucleoside that is an antiviral and anticancer agent. It can be used as a monophosphate or diphosphate. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine has been shown to inhibit the replication of DNA, RNA, and protein synthesis. This compound also has an activating effect on the immune system by inducing lymphocyte proliferation and increasing NK activity. It inhibits the growth of viruses such as HIV and influenza A virus. The purity of 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is high, with a CAS number of 11052282-2.</p>
    Formule :C39H37N5O7
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :687.76 g/mol

    Ref: 3D-ND08050

    1g
    327,00€
    5g
    709,00€
    10g
    1.051,00€
    25g
    1.834,00€
    500mg
    221,00€
  • 2'-Deoxycytidine HCl

    CAS :
    <p>2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.</p>
    Formule :C9H13N3O4·HCl
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :263.68 g/mol

    Ref: 3D-ND02591

    5g
    476,00€
    10g
    632,00€
    25g
    894,00€
    50g
    1.260,00€
    100g
    1.883,00€
  • 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate

    CAS :
    <p>3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.</p>
    Formule :C13H22N3O14P3
    Degré de pureté :Min. 95%
    Masse moléculaire :537.25 g/mol

    Ref: 3D-NP145591

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  • 3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine


    <p>3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine is a nucleoside that is synthesized by the modification of deoxyadenosine. It has antiviral and anticancer properties, as well as other novel applications. The synthesis of this compound can be achieved in two steps: first, the amino group is attached to the 3' carbon atom of the sugar ring by reacting with N6-(benzoyl)adenine. In the second step, a silyl group is attached to the 5' carbon atom of the sugar ring by reacting with tert-butyldimethylchlorosilane and DMT (dimethoxytrityl).</p>
    Formule :C44H50N6O6Si
    Degré de pureté :Min. 95%
    Masse moléculaire :786.99 g/mol

    Ref: 3D-NA59527

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  • 2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite

    CAS :
    <p>2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br&gt;br&gt;2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotides</p>
    Formule :C42H51N8O5P
    Degré de pureté :Min. 95%
    Masse moléculaire :778.9 g/mol

    Ref: 3D-PD09131

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  • N2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine


    <p>N2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine is a novel nucleotide that is activated by the addition of 2'-deoxyribonucleosides and has antiviral activity. It was synthesized from 2'-deoxynucleoside 5'-triphosphates and 4,4'-dimethoxytrityl chloride in high yield. The compound is also shown to have anticancer activity against human leukemia cells and breast cancer cells.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA34795

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  • 5-Azacytidine

    CAS :
    <p>An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.</p>
    Formule :C8H12N4O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :244.21 g/mol

    Ref: 3D-NA02947

    10g
    314,00€
    25g
    471,00€
    50g
    629,00€
    100g
    993,00€
    250g
    1.403,00€
  • 4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D- ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine


    <p>4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic activator that selectively activates the transcription of genes in cells. It has been shown to have anticancer activity and may be useful as a therapeutic agent for the treatment of certain cancers. 4C 7 (2dEB 3,5BT) 5I is also known to be an antiviral agent against HIV and influenza virus. The modification on the 2'-deoxyribose sugar moiety can enhance both activation and antiviral activities.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NC162932

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  • Flavin adenine dinucleotide

    CAS :
    <p>Flavin adenine dinucleotide, also known as FAD, plays a crucial role in several enzymatic reactions involved in metabolism. It is essential for the function of flavoproteins, which are involved in processes such as the electron transport chain and the citric acid cycle.</p>
    Formule :C27H33N9O15P2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :785.5 g/mol

    Ref: 3D-NF182245

    25mg
    264,00€
    50mg
    413,00€
    100mg
    588,00€
    250mg
    1.044,00€
  • 5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt

    CAS :
    <p>5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.</p>
    Formule :C9H12BrN2O8PNa2
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :Powder
    Masse moléculaire :433.06 g/mol

    Ref: 3D-NB09916

    1g
    838,00€
    2g
    1.472,00€
    5g
    3.325,00€
    250mg
    336,00€
    500mg
    508,00€
  • 5-Methylcytidine-5'-monophosphate

    CAS :
    <p>5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.</p>
    Formule :C10H16N3O8P
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :337.22 g/mol

    Ref: 3D-NM29555

    1mg
    254,00€
    2mg
    382,00€
    5mg
    543,00€
    10mg
    804,00€
    25mg
    1.516,00€
  • Fmoc morpholino guanosine monomer


    <p>Fmoc Morpholino Guanosine Monomer is a novel and modified nucleoside with antiviral and anticancer activities. It is synthesized from the ribonucleotide, deoxyribonucleotide, and phosphoramidite. Fmoc Morpholino Guanosine Monomer is an activator of RNA polymerase and inhibits cell proliferation in vitro. This compound has been shown to be a potential candidate for treatment of viral infections such as HIV-1, herpes simplex virus type 1, or influenza A virus.</p>
    Formule :C31H34ClN7O8P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :699.07 g/mol

    Ref: 3D-PF180530

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  • 5'-O-Pixylthymidine


    <p>5'-O-Pixylthymidine is a modified nucleoside that has been shown to have anticancer and antiviral activity. It is an analog of thymidine, which is a deoxynucleoside. 5'-O-Pixylthymidine can be converted into diphosphate form by addition of phosphoramidites or ribonucleosides. This nucleotide can also be used as a building block for the synthesis of oligonucleotides, which are synthetic DNA molecules with therapeutic applications.</p>
    Formule :C29H26N2O6
    Degré de pureté :Min. 95%
    Masse moléculaire :498.53 g/mol

    Ref: 3D-NP08579

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  • 1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil

    CAS :
    <p>1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agents</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND162854

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  • 5-Methoxy-2-thiouridine

    CAS :
    <p>5-Methoxy-2-thiouridine is the peracylated form of thiouracil. It is a reactive oxygen species, which can cause primary site lesions in cells. 5-Methoxy-2-thiouridine is a posttranscriptional modification that leads to conformational changes in the anticodon loop of tRNA molecules. This modification prevents the anticodon from pairing with its corresponding codon during translation, thereby inhibiting protein synthesis. The modifications also affect RNA processing and stability and lead to changes in gene expression.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-FM162894

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  • 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)uracil


    <p>1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)uracil is a synthetic nucleoside and a phosphoramidite. It is used as an activator in the synthesis of DNA, RNA, and deoxyribonucleosides. 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)uracil has antiviral and anticancer effects. It can be used to modify DNA and inhibit cancer cell proliferation. This product is high quality, novel, and high purity.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND137580

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  • Acetyl hypoxanthine

    CAS :
    <p>Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.</p>
    Formule :C7H6N4O2
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :178.15 g/mol

    Ref: 3D-NA158227

    25mg
    594,00€
    50mg
    724,00€
    100mg
    965,00€
  • 8-Hydroxyadenosine

    CAS :
    <p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>
    Formule :C10H13N5O5
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :283.25 g/mol

    Ref: 3D-NH08494

    1g
    883,00€
    2g
    1.494,00€
    100mg
    255,00€
    250mg
    477,00€
    500mg
    639,00€
  • 5'-O-p-Anisoyl-2'-deoxyuridine


    <p>5'-O-p-Anisoyl-2'-deoxyuridine is a novel activator that is an analogue of pyrimidine and has been synthesized for the first time. It belongs to the group of nucleosides and has been modified chemically. This compound can be used as a pharmaceutical drug for the treatment of cancer or viral infections.</p>
    Formule :C17H18N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :362.33 g/mol

    Ref: 3D-NA08690

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  • N6-Benzyladenosine 5'-monophosphate sodium salt monohydrate

    CAS :
    <p>N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.</p>
    Formule :C17H18N5Na2O7P·H2O
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :Powder
    Masse moléculaire :499.32 g/mol

    Ref: 3D-NB30216

    1mg
    455,00€
    2mg
    648,00€
    5mg
    1.343,00€
    10mg
    2.348,00€
  • TFA-aa-dUPhosphoramidite


    <p>TFA-aa-dUPhosphoramidite is a high quality, novel DNA phosphoramidite. It is used for the synthesis of deoxyribonucleosides and ribonucleosides. TFA-aa-dUPhosphoramidite has been shown to be an activator in the synthesis of RNA and DNA, and it is also resistant to degradation by nucleases. This product has CAS No.</p>
    Formule :C44H51N5O9P
    Degré de pureté :Min. 95%
    Masse moléculaire :824.88 g/mol

    Ref: 3D-PT57505

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  • 9-(β-D-Xylofuranosyl)adenine

    CAS :
    <p>9-(β-D-Xylofuranosyl)adenine is a nucleoside analog that inhibits the activity of adenine nucleotide. It has been shown to be effective against a wide range of viruses and bacteria, including HIV, herpes simplex virus, influenza A virus, and Mycobacterium tuberculosis. The chemical structure of 9-(β-D-Xylofuranosyl)adenine resembles that of adenosine and this similarity confers inhibitory properties on it. 9-(β-D-Xylofuranosyl)adenine is an analog of adenosine. The steric interactions between the intramolecular hydrogen bonds in 9-(β-D-Xylofuranosyl)adenine are weaker than those in adenosine, which allows it to bind more easily with the enzyme responsible for the conversion of adenosine to inosinic acid. This inhibition prevents the formation of ATP from AMP, leading</p>
    Formule :C10H13N5O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :267.24 g/mol

    Ref: 3D-FX144729

    25mg
    194,00€
    50mg
    337,00€
    100mg
    549,00€
    250mg
    1.155,00€
    500mg
    2.110,00€
  • 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine

    CAS :
    <p>Please enquire for more information about 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C13H15BrN2O7
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :391.18 g/mol

    Ref: 3D-ND04658

    1g
    148,00€
  • 3’-O-tert-butyldimethylsilyl-5’-O-DMT-N1-methylpseudouridine

    CAS :
    <p>3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1-methylpseudouridine is a synthetic nucleoside that is used in the synthesis of deoxyribonucleosides. It is an activator nucleoside that has antiviral activity and provides high purity, novel monophosphate nucleosides, and modified nucleosides. 3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1 methylpseudouridine has CAS No. 875302–43–5 and can be used for the synthesis of phosphoramidites or ribonucleotides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB162907

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  • 3’-Azido-3’-deoxy-5-fluoro-b-L-uridine

    CAS :
    <p>3’-Azido-3’-deoxy-5-fluoro-b-L-uridine is a novel, activator ribonucleoside that is an analog of the natural nucleoside uridine. It has high quality and purity. This compound is used to synthesize deoxyribonucleosides, diphosphate, phosphoramidites, modified, anticancer and antiviral agents.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA163021

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  • 2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt

    CAS :
    <p>2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt is a nucleoside analog of Adenosine-5'-triphosphate (ATP), a key player in cellular energy transfer. 2'(3')-O-(4-Benzoyl)benzoyl has been added to this molecule as well as a triethylammonium salt which helps to increase the stability of the molecule in solutions. 2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt has potential use as a tool for understanding how cells use ATP and how changes to ATP affect cellular processes. Other possible uses are in the study of how ATP interacts with enzymes.</p>
    Formule :C24H24N5O15P3·C6H15N
    Degré de pureté :Min. 75 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :816.58 g/mol

    Ref: 3D-NB29594

    5mg
    301,00€
    10mg
    389,00€
    25mg
    534,00€
    50mg
    928,00€
    100mg
    1.646,00€
  • 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine

    CAS :
    <p>5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND163002

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  • 2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

    CAS :
    <p>2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a modified purine nucleoside, protected with acetyl groups, which protect the sugar during chemical reactions. This compound is based on a purine ring and also contains an acetamido group at position 2, a chlorine atom at position 6 and a β-D-ribofuranosyl sugar.</p>
    Formule :C18H20ClN5O8
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :469.83 g/mol

    Ref: 3D-NA04442

    1g
    1.334,00€
    2g
    2.369,00€
    100mg
    239,00€
    250mg
    454,00€
    500mg
    781,00€
  • 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162940

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  • 4-Thiothymidine

    CAS :
    <p>4-Thiothymidine is a nucleoside analog that is converted to thymidine by the enzyme thymidine kinase. It has been shown to inhibit the growth of human skin cancer cells by binding to DNA duplexes and inhibiting the synthesis of new DNA strands. 4-Thiothymidine has also been shown to be effective against radiation-induced damage in cultured human cells and inhibits tumor growth in mice bearing a transplantable mouse skin cancer. 4-Thiothymidine can be used as an inhibitor for chemotherapy or radiation therapy for cancer patients. It is active on both site-specific and cell-specific gene targets, with a reactive hydrogen bond that helps stabilize its formation.</p>
    Formule :C10H14N2O4S
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Yellow Powder
    Masse moléculaire :258.3 g/mol

    Ref: 3D-NT06341

    1g
    747,00€
    2g
    1.259,00€
    5g
    2.650,00€
    250mg
    400,00€
    500mg
    532,00€
  • Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt


    <p>Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt is a novel nucleotide activator that has antiviral, anticancer, and ribonucleoside activities. This activator is a phosphoramidite monomer with an adenine base. The pharmaceutical industry uses this activator as a starting material in the synthesis of anticancer drugs and antiviral drugs. It is also used as a reagent in the production of modified DNA and RNA molecules for use in gene therapy and drug discovery.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA31345

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  • 2-Iodoadenosine

    CAS :
    <p>2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.</p>
    Formule :C10H12IN5O4
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :Powder
    Masse moléculaire :393.14 g/mol

    Ref: 3D-NI04749

    1g
    430,00€
    2g
    598,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    250,00€