Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine
CAS :4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine is a monophosphate of the nucleoside 5FU. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by competitively inhibiting the activity of thymidylate synthase, which converts dUMP to dTMP. 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine also induces apoptosis in neoplastic cells. This compound has high purity and quality, and can be used as a phosphoramidite for the synthesis of modified oligonucleotides.Formule :C10H10FNO4Degré de pureté :Min. 95%Masse moléculaire :227.19 g/molN4-Ethyl-2'-deoxycytidine
CAS :N4-Ethyl-2'-deoxycytidine is a novel nucleoside analog that inhibits the activity of DNA polymerase. It is used as an anticancer, antiviral and antiretroviral agent. N4-Ethyl-2'-deoxycytidine has been shown to be active against herpes simplex virus type 1 (HSV-1), HSV-2, cytomegalovirus (CMV), human immunodeficiency virus type 1 (HIV-1) and HIV-2 in vitro. This drug also has antiangiogenic properties due to its ability to inhibit the synthesis of vascular endothelial growth factor A. N4-Ethyl-2'-deoxycytidine is a modified nucleoside that can be phosphorylated by cellular enzymes, which activates it by converting it into a monophosphate or diphosphate form. This drug inhibits the production of RNA from DNA and also prevents proteinFormule :C11H17N3O4Degré de pureté :Min. 95%Masse moléculaire :255.27 g/molN6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt
CAS :N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt is a novel antiviral and anticancer agent that is a synthetic nucleoside analogue. It has been shown to be effective at inhibiting the growth of human cancer cells in vitro and in vivo. N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt binds to viral RNA, resulting in inhibition of protein synthesis and cell death.Formule :C14H18N5O6P·NaDegré de pureté :Min. 95%Masse moléculaire :406.29 g/mol2-(Methylthio)-4-(P-Tolylamino)Pyrimidine-5-Carboxylic Acid
CAS :2-(Methylthio)-4-(P-tolylamino)pyrimidine-5-carboxylic acid is an anticancer drug that is a novel, modified nucleoside. It has been shown to be active as a monophosphate and diphosphate in vitro. 2-(Methylthio)-4-(P-tolylamino)pyrimidine-5-carboxylic acid has also been shown to have antiviral activity against HIV and herpes simplex virus type 1 (HSV1).Formule :C13H13N3O2SDegré de pureté :Min. 95%Masse moléculaire :275.33 g/mol2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite is a novel modified nucleoside that is synthesized by the reaction of 2'-deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl] uridine with bis(2,4,6-trimethylbenzoyl)phosphine and then with tetrazole. This product inhibits the synthesis of viral RNA and DNA and has been shown to be effective against cancer cells in vitro.Formule :C44H49F3N5O9PDegré de pureté :Min. 95%Masse moléculaire :879.86 g/mol8-Bromoguanosine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS :8-Bromoguanosine-5'-triphosphate sodium salt is a nucleotide analog that inhibits the enzyme ribonucleotide reductase. This drug inhibits bacterial growth by interfering with protein synthesis and cell division. It binds to the purine riboswitch, which is an allosteric regulatory binding site on the ribosome, inactivating it. 8-Bromoguanosine-5'-triphosphate sodium salt also binds to the active site of bacterial RNA polymerase and inhibits DNA synthesis. The activity of this drug has been shown using a bacteriophage system in which the enzyme protein synthesis was inhibited by 8-bromoguanosine-5'-triphosphate sodium salt.Formule :C10H15N5O14P3Br·xNaDegré de pureté :Min. 95%Masse moléculaire :602.08 g/mol5'-O-DMT-2,3'-anhydrothymidine
CAS :5'-O-DMT-2,3'-anhydrothymidine is a solvent that is used for labeling nucleic acids. It can be used in positron emission tomography (PET) imaging as a diagnostic tool for cancer and other diseases. 5'-O-DMT-2,3'-anhydrothymidine is also used to carry the radioactive isotope fluorodeoxyglucose (FDG) in positron emission tomography (PET). The FDG is labeled with the PET tracer and then injected into the patient's body. This allows for whole-body visualization of glucose metabolism and tumor cell uptake.Formule :C31H30N2O6Degré de pureté :Min. 95%Masse moléculaire :528.61 g/mol2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine
2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine is a nucleoside that is used in the synthesis of antiviral drugs. It is a modified monophosphate with a 3',5'-di-O-benzoyl group and 2'-deoxyribose. This substance can be prepared from the corresponding 2,6-dichloropurine by reaction with chloroacetaldehyde diethyl acetal. 2,6 Dichloro 9-(3',5'-di-O-benzoyl) purine has been shown to have anticancer activity against various human cancer cell lines in vitro and in vivo.Degré de pureté :Min. 95%1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is a novel, activator ribonucleosides deoxyribonucleosides diphosphate phosphoramidites modified anticancer antiviral monophosphate nucleosides synthetic high purity CAS No. It has been shown to have anticancer and antiviral properties. This compound also inhibits the replication of HIV in vitro.Formule :C15H21N5O5Degré de pureté :Min. 95%Masse moléculaire :351.37 g/mol2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde
CAS :2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde is an antiviral and anticancer phosphoramidite. It is a novel monophosphate nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase. 2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde has been shown to be effective against influenza virus, HIV, Herpes Simplex Virus, and human leukemia cells. This compound is not active against bacteria or fungi.Formule :C10H13N3ODegré de pureté :Min. 95%Masse moléculaire :191.23 g/mol3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine
3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine (Zidovudine) is a nucleoside analog that inhibits the replication of human immunodeficiency virus type 1. It is phosphorylated by cellular enzymes to form the active triphosphate form, which incorporates into viral DNA and causes chain termination. Zidovudine has been used in the treatment of HIV infection and AIDS. This drug also has antiviral activity against other retroviruses such as HIV type 2 and measles virus, as well as some DNA viruses, such as herpes simplex type 1. Zidovudine may be useful for the treatment of cancer, particularly Kaposi's sarcoma.Degré de pureté :Min. 95%N2-Isobutyryl-5’-O-DMT-morpholinoguanosine-N’-CE phosphoramidite
CAS :A morpholino amidite
Formule :C44H55N8O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :838.93 g/molN6-Benzoyl-5’-O-DMT-morpholinoadenosine-N’-CE phosphoramidite
CAS :A morpholino amiditeFormule :C47H53N8O6PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :856.95 g/mol3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine
CAS :3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a novel antiviral agent that has been synthesized as a high quality, high purity monophosphate. It is a modified nucleoside that is used to synthesize phosphoramidites. It has antiviral activity against herpes simplex virus type 1 and 2, and cytomegalovirus. 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is also an inhibitor of the DNA polymerase enzyme and inhibits the synthesis of viral DNA in infected cells. This drug can be used for the treatment of infections caused by these viruses.Formule :C13H14BrFN2O7Degré de pureté :Min. 95%Masse moléculaire :409.16 g/mol2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde
CAS :2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a Ribonucleside, Deoxyribonucleoside, Activator, Antiviral, Synthetic and Modified DNA Nucleoside. It has been shown to inhibit viral replication in vitro by interfering with the formation of the viral diphosphate. 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a ribonucleotide that is synthesized from commercially available starting materials. This compound has shown to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of AIDS. 2-Methylsulfanyl-4-phenylamino pyrimidine 5 carbaldehyde (2MSAP) was found to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment ofFormule :C12H11N3OSDegré de pureté :Min. 95%Masse moléculaire :245.3 g/mol5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine
CAS :5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine is a nucleoside analog that is an activator of DNA polymerase. It has been shown to have anticancer activity in vitro and in vivo. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine was found to inhibit the proliferation of leukemia cells, human colon cancer cells, and human prostate cancer cells. This compound also inhibits viral replication by affecting the synthesis of viral DNA and RNA. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine may be used as a research tool for studying the mechanism of action of antiviral drugs suchFormule :C37H37F3N4O9Degré de pureté :Min. 95%Masse moléculaire :738.74 g/mol2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one
CAS :2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :267.24 g/mol1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine
CAS :1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).Formule :C9H12ClN3O4Degré de pureté :Min. 95%Masse moléculaire :261.66 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt is a nucleoside analog that inhibits telomerase. It binds to the catalytic subunit of telomerase, which is an RNA-dependent DNA polymerase that synthesizes telomeres during DNA replication. This binding prevents the enzyme from extending the 3' end of the DNA strand, inhibiting cell proliferation and leading to apoptosis. Telomerase inhibition has been shown to have an inhibitory effect on insulin resistance in mice. 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt also inhibits protein kinases, but does not inhibit phosphatases or other enzymes.Formule :C11H17N4O13P3·xLiDegré de pureté :Min. 95%Masse moléculaire :506.19 g/mol5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine
5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside analog that has antiviral, anticancer, and high purity properties. It is an activated nucleotide that can be incorporated into DNA or RNA. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a modified nucleoside with the deoxyribose sugar replaced by an isopropylidene group. This modification prevents the drug from being metabolized and excreted from the body. The drug is used to treat various cancers such as leukemia and lymphoma, as well as herpes simplex virus infections. It also has been shown to have antimicrobial properties against bacteria, fungi, and viruses.Formule :C12H15ClIN3O4Degré de pureté :Min. 95%Masse moléculaire :427.63 g/mol
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