Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite
CAS :2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of DNA. It can be used to treat AIDS, because it inhibits the reverse transcriptase enzyme. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite also has anticancer properties, which is due to its ability to inhibit RNA and protein synthesis in cancer cells. This compound has been synthesized by reacting 5'-O-DMT cytidine with methylacetoacetate under standard conditions. The modified nucleoside has a high purity, high quality, and novel structure.Formule :C47H64N7O7SiDegré de pureté :Min. 95%Masse moléculaire :867.14 g/mol7’-O-DMT-morpholino-5-methyluridine-N’-CE phosphoramidite
CAS :a morpholino amiditeFormule :C40H50N5O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :743.83 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone
4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone is a novel nucleoside that has been modified by the addition of a 2'-deoxy, 3',5'-di-O-toluoyl group on the sugar moiety. This modification increases the stability of 4AMDT in serum and enhances its antiviral activity against DNA and RNA viruses. It also inhibits the proliferation of cancer cells and induces cell death by inhibiting protein synthesis.Formule :C29H29N5O6Degré de pureté :Min. 95%Masse moléculaire :543.57 g/mol2'-Deoxy-5-hydroxyuridine 5'-triphosphate
CAS :2'-Deoxy-5-hydroxyuridine 5'-triphosphate (doxorubicin) is a cytotoxic and chemotherapeutic agent that interferes with DNA replication. It is an oxidized form of the natural pyrimidine base thymine. The drug blocks DNA synthesis by preventing the incorporation of uracil into the newly synthesized strand, which causes strand breaks. Doxorubicin has been shown to be effective in treating a variety of cancers, including those of the breast, ovaries, bladder, and stomach. This drug can also cause severe side effects such as heart damage and hearing loss due to its interaction with cellular oxygen metabolism.Degré de pureté :Min. 95%6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS :6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside that is used as an anticancer and antiviral agent. It is synthesized from 9-(3',5'-di-O-benzoyl)-2'-deoxyribofuranosyl chloride, which is then chlorinated to form 6-chloro purine. This product has been shown to be active against human DNA tumor cells and other viruses in vitro. 6CPA, like other nucleosides, can be phosphorylated on the 3' or 5' position of the sugar moiety, yielding monophosphate or diphosphate derivatives respectively. The monophosphate derivative of 6CPA has a higher cytotoxicity than the diphosphate derivative. The deoxyribose sugar moiety canFormule :C24H18CIFN4O5Degré de pureté :Min. 95%Masse moléculaire :496.89 g/molThymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt
Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is a novel, modified nucleoside that is chemically synthesized from 2,3,4,6-tetraaminopyrimidine. It has antiviral activity and can be used to treat HIV infections. It is an active form of thymidine and inhibits the synthesis of viral DNA by blocking the activity of viral DNA polymerase in reverse transcription. This drug also exhibits anticancer activity by preventing cell proliferation and inducing apoptosis. Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is high purity with a CAS number of 63625-04-9.
Formule :C16H24N2O15P2Na2Degré de pureté :Min. 95%Masse moléculaire :592.29 g/mol3'-Azido-3'-deoxy-5-methylcytidine
CAS :3'-Azido-3'-deoxy-5-methylcytidine (AZDMC) is a novel nucleoside analog that inhibits viral replication. AZDMC is an activator of cellular DNA synthesis, which is essential for the replication of DNA and the production of RNA. It also has antiviral activity against influenza A and B viruses. The chemical name for AZDMC is 3'-azido-3'-deoxy-5-methylcytidine monophosphate (AMP). The CAS number for AZDMC is 1282040-14-5. It can be synthesized with high purity and quality by Ribonucleosides, Modified, Deoxyribonucleosides, Nucleosides, Phosphoramidites.
Degré de pureté :Min. 95%N6-Benzoyl-3'-deoxyadenosine
CAS :N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.Formule :C17H17N5O4Degré de pureté :Min. 95%Masse moléculaire :355.35 g/molAdenosine HCl
CAS :Adenosine is a nucleoside that is found in all cells. It plays an important role in the formation of ATP and as a neurotransmitter. Adenosine also acts on a receptor to promote vasodilation, improve cardiac contractility, and increase cardiac output. Adenosine has been found to be effective in preventing congestive heart failure in rats with myocardial infarction. In humans, adenosine has been shown to have beneficial effects on metabolic disorders such as diabetes mellitus and diabetic neuropathy. Adenosine HCl is an acid salt of adenosine that can be used for the treatment of coronary artery disease.Formule :C10H13N5O4·HClDegré de pureté :Min. 95%Masse moléculaire :303.7 g/mol2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside analogue that inhibits the growth of cancer cells. It is used in the synthesis of oligonucleotides, which are used as drugs to treat cancers. This product has high purity and good quality and has been shown to be effective against cancer cells.
Formule :C39H46FN4O8PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :748.8 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine-3'-O-succinate triethylammonium salt
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine-3'-O-succinate triethylammonium salt is a synthetic nucleoside. It is used for the treatment of HIV infection. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT)-2'-fluoro -b -D -arabinofuranosyl) -5 methylcytosine (ADT) inhibits viral replication by inhibiting the activity of reverse transcriptase, which is an enzyme that synthesizes DNA from RNA. ADT is activated to its active form by phosphorylation with a kinase and then converted to diphosphate ADP by the enzyme pyrophosphatase. ADP then acts as a substrate for DNA polymerases, incorporating into newly synthesized DNA
Formule :C42H40FN3O10·C6H16NDegré de pureté :Min. 95%Masse moléculaire :868 g/mol2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine
CAS :2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine (FdA) is a synthetic nucleoside that was designed for use as a dietary supplement to inhibit carcinogenesis. It is an analog of guanosine and is phosphorylated by cellular kinases to form 2'-deoxy-8-(9H-fluoren-2-ylamino)-inosine monophosphate. FdA inhibits the process of DNA replication in mammalian cells, which may be due to its ability to bind single stranded DNA. This drug has been shown to reduce the mutation frequency and increase the life span of mice with bladder cancer.Formule :C23H22N6O4Degré de pureté :Min. 95%Masse moléculaire :446.46 g/mol6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione
CAS :6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione is a nucleoside analog that has shown to be an activator of the ribonucleotide reductase enzyme. It has also been shown to have anticancer activity. 6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione inhibits DNA synthesis by binding to the DNA molecule at the site of incorporation and preventing its duplication. This compound also inhibits RNA synthesis by binding to the RNA molecule at the site of incorporation and preventing its duplication. It has been shown to inhibit cancer cell growth in culture and can be used as a chemotherapeutic agent.Formule :C12H11IN2O2Degré de pureté :Min. 95%Masse moléculaire :342.13 g/mol2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde
CAS :2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde is a modified nucleoside that has been shown to be an effective antiviral and anticancer agent. This compound inhibits viral replication by blocking the synthesis of viral DNA, and also exhibits cytotoxic activity against cancer cells. 2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde is an activator of ribonucleotide reductase and deoxyribonucleotide reductase and can be used in the synthesis of nucleosides, DNA, or phosphoramidites.Formule :C8H10N2O2Degré de pureté :Min. 95%Masse moléculaire :166.18 g/molDihydrozeatin riboside-5'-monophosphate sodium salt
CAS :Dihydrozeatin riboside-5'-monophosphate sodium salt is a cytokinin that belongs to the group of indole compounds. It has been shown to inhibit the biosynthesis of ethylene, which prevents fruit from ripening. Dihydrozeatin riboside-5'-monophosphate sodium salt is also able to inhibit the synthesis of adenosine, another plant hormone that inhibits growth and promotes dormancy in plants. The bioassay for this product has been done with amanita muscaria, an edible mushroom found in North America and Europe. This mushroom contains dihydrozeatin as well as other related compounds such as zeatin, which can be converted into dihydrozeatin by enzymes present in the intestines. The symptoms of poisoning by this mushroom include vomiting and diarrhea, owing to its effects on intestinal motility.Formule :C15H22N5Na2O8P·H2ODegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :495.33 g/mol5’-O-DMT cET-N6-benzoyladenosine 3’-OCE amidite
CAS :Please enquire for more information about 5'-ODMT cEt N-Bz A Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C49H54N7O8PMasse moléculaire :899.97 g/mol8-Oxo-7-thioguanosine
CAS :8-Oxoguanosine monophosphate (8-oxoGMP) is a synthetic nucleoside that is activated by the enzyme thioredoxin reductase and phosphorylated to form 8-oxoGTP. The anticancer activity of 8-oxoGMP is due to its ability to inhibit ribonucleotide reductase, which reduces the production of DNA and RNA in cells. This product has been shown to inhibit HIV replication in vitro and in vivo. It also inhibits viral replication by inhibiting the synthesis of viral nucleic acids such as DNA, RNA, and deoxyribonucleic acid (DNA).Formule :C10H12N4O6SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :316.29 g/mol3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
CAS :3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine is a nucleoside derivative that has antiviral activity. It is synthesized by the condensation of 2,3,5-trihydroxybenzoic acid with 3'-chloro-5'-fluoroacetophenone in the presence of pyridine and triethylamine. The nucleoside has been shown to be an effective inhibitor of HIV replication in vitro. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine also inhibits DNA synthesis in human lymphocytes at concentrations of 5 μM or less. This compound can be used as an activator for DNA polymerases and phosphoramidites for DNA synthesis.Formule :C23H17Cl2FN2O7Degré de pureté :Min. 95%Masse moléculaire :523.29 g/mol3',5'-Di-O-acetyl-N2-acetyl-O6-diphenylcarbamoyl-2'-deoxy-D-guanosine
3',5'-Di-O-acetyl-N2-acetyl-O6-diphenylcarbamoyl-2'-deoxy-D-guanosine is a synthetic nucleoside that has been modified with an acetyl group at the 3' and 5' positions of the sugar. It has antiviral, anticancer, and antiretroviral activities against HIV. This nucleoside has also been shown to inhibit human leukemia cells in vitro by binding to DNA, inhibiting its synthesis. The drug is currently undergoing clinical trials for the treatment of AIDS patients.Degré de pureté :Min. 95%2'-Deoxyguanosine-5'-monophosphate free acid
CAS :2'-Deoxyguanosine-5'-monophosphate free acid (dGMP) is a nucleotide that can be used as a substrate to measure the activity of protein kinase C. It is also a precursor in DNA synthesis, and its incorporation into DNA is catalyzed by polymerase chain reaction. 2'-Deoxyguanosine-5'-monophosphate free acid has been shown to inhibit transcriptional regulation, which may be related to its interaction with nuclear DNA. Furthermore, it has been shown to have an antioxidant effect due to its ability to donate electrons. 2'-Deoxyguanosine-5'-monophosphate free acid has also been shown to react with sodium salts in plasma mass spectrometry experiments, and titration calorimetry experiments have shown that it reacts with calcium ions in vitro.br>Formule :C10H14N5O7PDegré de pureté :Min. 95%Masse moléculaire :347.22 g/mol
