Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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N6-Benzoyl-7-deaza-2'-deoxy-5'-O-DMT-7-iodoadenosine
N6-Benzoyl-7-deaza-2'-deoxy-5'-O-DMT-7-iodoadenosine is a modified nucleoside that is used as an antiviral and anticancer agent. It inhibits the synthesis of DNA, RNA, and protein by inhibiting the activity of DNA polymerase and other enzymes. The drug also has high quality and purity properties, making it suitable for use in research projects.Degré de pureté :Min. 95%2-Methanesulfonyl-4-phenyl-pyrimidine
CAS :2-Methanesulfonyl-4-phenyl-pyrimidine is a novel nucleoside phosphoramidite that is synthesized by the reaction of 2,4-dichlorophenyl pyrimidine with methanesulfonyl chloride and 3′-(dimethylamino)propylphosphine. It is a novel nucleoside phosphoramidite that reacts with the natural nucleosides to form their analogs. This product can be used as an antiviral agent or anticancer agent.Degré de pureté :Min. 95%7-Chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine
CAS :7-Chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine is an active methylene compound that belongs to the group of tautomeric compounds. It is a pyrimidine derivative and a sodium salt of the amine. 7-Chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine can be prepared from 2,4,6,-trichloropyrimidine by adding sodium hydride in dimethylformamide. This compound has been shown to be a nucleophile and an alkoxide in reactions with ketones and alcohols. 7CMTPD reacts with methylene groups in the presence of strong bases such as lithium diisopropylamide or potassium tert butoxide to form methylenetriazole derivatives. 7CMTPD can also react with nucleophilesDegré de pureté :Min. 95%5-Fluoro-2'-o-methyl-4-(methylithio)uridine
CAS :5-Fluoro-2'-o-methyl-4-(methylithio)uridine (5F-OMe-4MSU) is a novel anticancer drug that has been synthesized by modification of uridine. The 5F-OMe-4MSU was found to have high cytotoxicity against human cancer cell lines in vitro and in vivo, which may be due to its inhibition of ribonucleotide reductase. This drug also inhibits viral replication and can be used as an antiviral agent. 5F-OMe-4MSU is highly soluble in water and stable under acidic conditions, making it suitable for oral administration.Formule :C11H15FN2O5SDegré de pureté :Min. 95%Masse moléculaire :306.31 g/mol2-Chloro-4-[2-(4-Fluorophenyl)Ethyl]-6-Methylpyrimidine
CAS :2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine is a synthetic nucleoside analog that inhibits viral DNA synthesis by acting as an inhibitor of the viral enzyme ribonucleotide reductase. 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine has been shown to be effective against various viruses, including HIV and herpes simplex virus 1. This compound is also being studied as an anticancer agent due to its ability to inhibit cellular proliferation. 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine is a phosphoramidite that can be used in the synthesis of modified nucleosides with novel antiviral or anticancer activity.
Formule :C13H12ClFN2Degré de pureté :Min. 95%Masse moléculaire :250.7 g/molCytidine-5'-triphosphate, lithium salt
Cytidine-5'-triphosphate, lithium salt (CTP, Li) is a monophosphate that is used as a cofactor in the synthesis of DNA and RNA. It is also used for the treatment of viral infections. CTP, Li has antiviral activity against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), varicella zoster virus (VZV), human cytomegalovirus (CMV) and Epstein-Barr virus (EBV). CTP, Li can be used to inhibit the growth of cancer cells by modifying DNA.Degré de pureté :Min. 95%2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer), lithium salt
2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) is a synthetic nucleoside that acts as an antiviral, anticancer and antineoplastic agent. It has been shown to inhibit the replication of DNA and RNA by inhibiting the activity of ribonucleoides. 2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) can be used in combination with other antiviral agents such as acyclovir or valacyclovir to treat herpes simplex virus type 1 infections. The drug is also effective against HIV, with a potency similar to that of zidovudine. It has been shown to be active in the treatment of leukemia, lymphoma, Hodgkin's disease and some solid tumors.Degré de pureté :Min. 95%3'-Deoxy-N6-octanoyladenosine
CAS :3'-Deoxy-N6-octanoyladenosine is a nucleoside that is used to synthesize DNA, RNA, and other nucleic acid molecules. It has antiviral and anticancer properties. 3'-Deoxy-N6-octanoyladenosine has been shown to be an activator of phosphoramidites in the synthesis of DNA. This compound also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA in cells. The purity of this product is >98% and it can be used for research purposes or as a pharmaceutical intermediate.Formule :C18H27N5O4Degré de pureté :Min. 95%Masse moléculaire :377.44 g/mol2-Methylthio-6-chloro-9-methylpurine
CAS :2-Methylthio-6-chloro-9-methylpurine is an activator that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA and RNA. 2-Methylthio-6-chloro-9-methylpurine has been shown to inhibit viral replication and may be used as a antiviral agent. This compound has novel properties and is a potential anticancer drug due to its ability to inhibit the growth of tumor cells.Formule :C7H7CIN4SDegré de pureté :Min. 95%Masse moléculaire :318.14 g/mol5-Bromo-2'-deoxyuridine 5'-diphosphate sodium salt - 10mM aqueous solution
5-Bromo-2'-deoxyuridine 5'-diphosphate sodium salt - 10mM aqueous solution is a monophosphate nucleoside and an antiviral agent that inhibits viral DNA synthesis by inhibiting the activity of ribonucleotide reductase. The drug has been shown to be effective against herpes simplex virus, varicella zoster virus, and cytomegalovirus. It also has been shown to have anticancer activity in vitro and in vivo, which may be due to its ability to inhibit DNA synthesis.Formule :C9H13N2O11P2BDegré de pureté :Min. 95%Masse moléculaire :397.96 g/mol4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranosyl 5'-triphosphate
CAS :4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a novel nucleoside analog that has been shown to have antiviral and anticancer activities. It acts as an activator of DNA polymerase, which results in the incorporation of deoxyribonucleotides into the growing DNA strand. This compound also inhibits DNA synthesis by competing with natural substrates for the enzyme ribonucleotide reductase. 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a modified nucleoside that has been synthesized by replacing the phosphate group with diphosphate group on the sugar moiety. The chemical name for this compound is 4-(2'-deoxy-βFormule :C17H22N5O13P3Degré de pureté :Min. 95%Masse moléculaire :597.3 g/mol3'-Deoxy-3'-fluoro-5'-O-tritylthymidine
CAS :3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.Formule :C29H27FN2O4Degré de pureté :Min. 95%Masse moléculaire :486.53 g/mol2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate
2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate is a synthetic nucleoside analog with antiviral and anticancer activity. It is an analogue of cytidine, which is a component of DNA and RNA. 2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase in virus replication, which blocks the synthesis of viral proteins. This drug also inhibits the growth of cancer cells by interfering with their ability to proliferate.Degré de pureté :Min. 95%2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine
CAS :2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine (FMA) is an antiviral nucleoside that has been shown to inhibit the growth of human T lymphocytes, human hepatoma cells and mouse lymphoma L5178Y cells. It also inhibits the replication of HIV in vitro and has been shown to be effective against other viruses such as herpes simplex virus type 1 and 2, cytomegalovirus, Epstein Barr virus, varicella zoster virus and vaccinia. FMA is a phosphoramidite compound that can be used in DNA synthesis. It is also a monophosphate analog of arabinoadenosine that can be used as an activator of deoxyribonucleosides. This novel compound can be modified to synthesize diphosphates or phosphoramidites.
Formule :C11H14FN5O4Degré de pureté :Min. 95%Masse moléculaire :299.26 g/mol5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine
5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine is a novel nucleotide analog with antiviral and anticancer properties. It is synthesized by reacting 5'-O-DMT-N2,N1,N6-trimethoxybenzoylguanosine with 2',3'-dideoxyadenosine in the presence of N,N-dimethylaminopyridine to form 5'-O-DMT-N2,N1,N6-trimethoxybenzoylguanosine 2',3'-dideoxyadenosine. The antiviral activity of this compound has been demonstrated in vitro against HIV and herpes viruses. 5'-O-DMT-N2,N1,N6 -trimethoxybenzoylguanosine 2',3' -dideoxyadenosine alsoFormule :C34H35FN6O6Degré de pureté :Min. 95%Masse moléculaire :642.68 g/mol2-Deoxy-3,5-di-O-toluoyl-a-D-ribofuranosyl cyanide
2-Deoxy-3,5-di-O-toluoyl-a-D-ribofuranosyl cyanide is a novel anticancer agent that has been shown to have potent antiviral and antiproliferative properties. It is a phosphoramidite monophosphate with a CAS number of 313214-62-0. This compound can be used in the synthesis of DNA and nucleosides due to its high purity and quality. 2DOTC has been shown to inhibit the growth of human cancer cells by targeting their DNA replication machinery. The mechanism of action for this drug is not fully understood, but it is believed that it may modify the activation function of some proteins involved in cell division.Degré de pureté :Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine
CAS :2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine is a synthetic nucleoside that is used in the synthesis of DNA, RNA and other nucleosides. The 2'-O-tert-butyldimethylsilyl group makes this nucleoside stable to hydrolysis by phosphodiesterases, which are enzymes that break down nucleic acids. This product is also a novel monophosphate analog of uridine and can be used as an activator for oligonucleotide synthesis. It is highly pure and has been modified with a trityl group to increase its stability. The CAS number for this product is 117136-35-3.Formule :C34H40N2O6SiDegré de pureté :Min. 95%Masse moléculaire :600.78 g/molN6-Benzoyl-2'-deoxy-5-O-DMT-adenosine 3'-phosphonate triethylammonium salt
CAS :N6-Benzoyl-2'-deoxy-5-O-DMT-adenosine 3'-phosphonate triethylammonium salt is a potent antiviral agent that has been shown to inhibit the replication of DNA. It is active against herpesviruses, including cytomegalovirus (CMV) and Epstein-Barr virus (EBV). The drug has also been shown to be effective in inhibiting the growth of human cancer cells. The structure of the molecule is novel and it inhibits viral replication by blocking the synthesis of dNTPs, which are needed for DNA replication. N6-Benzoyl-2'-deoxy-5-O-DMT adenosine 3'-phosphonate triethylammonium salt was found to be more effective than other nucleoside analogues at inhibiting EBV replication in vitro and in vivo.Formule :C38H35N5O8P·C6H16NDegré de pureté :Min. 95%Masse moléculaire :822.89 g/mol2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a synthetic nucleoside that has shown anticancer and antiviral properties. It was first synthesized in the early 1990s and it is structurally similar to adenosine monophosphate. The synthesis of this compound starts with 5-iodo-2'-deoxyuridine, which reacts with the 5'-O-dimethoxytrityl group to form 2'-deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite. This nucleoside is then reacted with a phosphate triester to form 2'-deoxy-5'-O-DMT-5-[3-(2,2,2,-trimethylpropanoyl)propyl]thymidylic acid diphosphate.Formule :C39H46IN4O8PDegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :856.7 g/mol
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