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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å


    N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å is a nucleoside that has antiviral activity. It is the monophosphate, ribonucleoside, and diphosphate analog of adenosine. The novel analog N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å has been shown to be an effective anticancer drug and also to activate gene expression in cultured cells. This nucleoside can be used in the synthesis of DNA, as well as phosphoramidites for chemical synthesis of deoxyribonucleic acid (DNA).

    Degré de pureté :Min. 95%
    Couleur et forme :Powder

    Ref: 3D-NB11607

    1g
    300,00€
    5g
    538,00€
    10g
    906,00€
  • N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine

    CAS :
    N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine is a synthetic nucleoside that has antiviral and anticancer properties. It is an activator of deoxyribonucleosides and can be used to synthesize DNA, RNA, or other modified nucleosides. This compound is modified with acetyl groups at the 2' position and 5' position of the ribose sugar to increase its stability in biological systems. N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine has been shown to inhibit viral replication by acting as a monophosphate or diphosphate and inhibiting the synthesis of viral DNA.
    Formule :C32H32IN3O7
    Degré de pureté :Min. 95%
    Masse moléculaire :697.52 g/mol

    Ref: 3D-ND57519

    1g
    305,00€
    2g
    437,00€
    5g
    583,00€
  • N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine

    CAS :
    N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine is a nucleoside analog. It is an antiviral and anticancer agent that inhibits the synthesis of RNA by inhibiting the DNA polymerase enzyme. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine has been shown to be active against both DNA and RNA viruses, including herpesviruses. It has also been shown to have anti-inflammatory effects.
    Formule :C24H33N5O5Si
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :499.64 g/mol

    Ref: 3D-NB178928

    3g
    5.067,00€
  • N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine


    N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine is an antiviral nucleoside that is a phosphoramidite. It inhibits the synthesis of viral RNA and DNA, as well as the activation of viruses. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5 methylcytidine is a novel nucleoside analog with anticancer activity and good solubility in organic solvents. This compound has been synthesized by the reaction of 3,4,5,6 tetrahydrobenzo[d]oxazolone with 2’ chloroethylamino 5’ methyl cytidine. The purity of this compound is very high (>98%). The CAS number for this compound is 10
    Degré de pureté :Min. 95%

    Ref: 3D-NB167519

    250mg
    304,00€
    500mg
    383,00€
  • 5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine

    CAS :
    5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine is a monophosphate nucleoside. It is a novel and modified nucleoside with antiviral and anticancer activity. 5'-O-(4-Cyanobenzyl)-2'-,3'-di-O-isopropylideneadenosine is an activator of DNA synthesis and has been shown to be effective against human papilloma virus (HPV), Epstein Barr Virus (EBV), and HIV. This compound also has high purity, CAS No. 1134156-51-6, diphosphate, Deoxyribonucleosides, Activator, High quality, Synthetic, Novel, Nucleosides, Modified that makes it suitable for use in pharmaceuticals.
    Degré de pureté :Min. 95%

    Ref: 3D-NC162855

    25mg
    305,00€
    50mg
    401,00€
    100mg
    572,00€
  • 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine


    2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a nucleoside that is used in the production of DNA and RNA. It is an activator of phosphoramidites, which are used to synthesize oligonucleotides. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can be used as an anti-cancer drug and has antiviral activity. It has been shown to inhibit the replication of HIV by interfering with viral enzymes such as reverse transcriptase and integrase. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can also be used for the treatment of influenza A virus infections. This drug is highly purified, with a high quality, monophosphate form as well as a diphosphate form. There are no known side effects associated with this product.!--

    Formule :C32H30F3N3O8
    Degré de pureté :Min. 95%
    Masse moléculaire :641.61 g/mol

    Ref: 3D-ND08249

    25g
    À demander
  • 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine

    CAS :
    3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.
    Formule :C27H28N2O8
    Degré de pureté :Min. 95%
    Masse moléculaire :508.50 g/mol

    Ref: 3D-XDA97493

    250mg
    1.120,00€
  • Lutonarin

    CAS :
    Lutonarin is a naturally occurring compound in the plant Pueraria lobata. It has been shown to have anti-cancer properties and can be used as an alternative to radiation therapy for cancer treatment. Lutonarin is a membrane-hyperpolarizing agent that is able to pass through the cell membrane, leading to membrane hyperpolarization. Lutonarin also inhibits the production of gamma-aminobutyric acid (GABA), which leads to increased cell proliferation and inhibition of root formation. Lutonarin has been found to inhibit enzyme activities, such as glucose monitoring and protocatechuic acid, phenolic acid, and crystalline cellulose degradation. This leads to reduced glucose levels in blood plasma and reduced degradation of polysaccharides in roots.
    Formule :C27H30O16
    Degré de pureté :Min. 95%
    Masse moléculaire :610.5 g/mol

    Ref: 3D-NL180767

    5mg
    1.256,00€
  • Nicotinamide guanine dinucleotide sodium salt

    CAS :

    Nicotinamide guanine dinucleotide sodium salt is a nucleoside that is the product of the reaction between nicotinamide and guanosine triphosphate. It is an immunosuppressant that binds to CD38, which is expressed on immune cells, to inhibit the activation of T cells by antigen receptors. Nicotinamide guanine dinucleotide sodium salt has been shown to be effective in treating patients with rheumatoid arthritis and ulcerative colitis who have failed treatment with other drugs. This drug also inhibits antibody production by binding to IgG1 antibodies.

    Formule :C21H28N7O15P2·xNa
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White To Yellow Solid
    Masse moléculaire :680.43 g/mol

    Ref: 3D-NN46649

    5mg
    606,00€
    10mg
    956,00€
    25mg
    1.802,00€
  • Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution


    Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution is a novel nucleotide analogue that is synthesized by the coupling of a deoxyribonucleoside with a diphosphate. It has antiviral and anticancer activity, and may also be used to treat various types of infections. Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution is an excellent activator of DNA polymerase in vitro, which can be used in the synthesis of DNA or RNA. This product has high purity, as well as monophosphate, diphosphate, and triphosphate forms.
    Formule :C28H46N7O17P3S·xLi
    Degré de pureté :Min. 95%
    Masse moléculaire :877.69 g/mol

    Ref: 3D-NB32056

    800µg
    1.110,00€
  • 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine


    2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine is a DNA synthesis inhibitor. It is modified with a 2'-deoxy-5'-O-dimethoxytrityl group on the 2' position and an N2,N2-(isobutyryl) guanine moiety on the 5' position. This compound inhibits DNA synthesis by forming a covalent bond to the 3' phosphate of DNA. This product is synthesized in high purity and quality. It can be used for anticancer research or as an activator for phosphoramidites for the synthesis of DNA. CAS No.: 63787-03-6
    Degré de pureté :Min. 95%

    Ref: 3D-PD170431

    1g
    18.241,00€
  • 5'-O-DMT-thymidine 3'-thiophosphoramidite


    5'-O-DMT-thymidine 3'-thiophosphoramidite is a nucleoside that is used as a building block for the synthesis of DNA and RNA. The compound is also used to create antiviral drugs, anticancer agents, and novel drugs with antimicrobial properties. The chemical structure of 5'-O-DMT-thymidine 3'-thiophosphoramidite has been modified from the natural ribonucleoside thymidine. This modification prevents the phosphorylation of 5'-O-DMT-thymidine 3'-thiophosphoramidite by cellular kinases, which makes this compound more stable in vivo.
    Formule :C44H48N3O8PS2
    Degré de pureté :Min. 95%
    Masse moléculaire :841.97 g/mol

    Ref: 3D-PD46018

    250mg
    741,00€
  • 3'-epi-idoxuridine

    CAS :
    3'-Epi-idoxuridine is a nucleoside analog that inhibits viral DNA synthesis. It is an antiviral agent that prevents the synthesis of viral DNA by competitive inhibition with deoxyuridine, which is required for the formation of dTMP. 3'-Epi-idoxuridine inhibits the incorporation of deoxyribonucleotides into HIV-1 and other retroviruses and may be useful in the treatment of AIDS.
    Formule :C9H11IN2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :354.1 g/mol

    Ref: 3D-NE16543

    2mg
    305,00€
    5mg
    444,00€
    10mg
    719,00€
    25mg
    1.167,00€
    50mg
    2.066,00€
  • 2'-Deoxy-N6,N6-dimethyladenosine


    2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.
    Degré de pureté :Min. 95%

    Ref: 3D-ND159727

    1g
    À demander
    100mg
    5.675,00€
    250mg
    À demander
    500mg
    À demander
  • 6-(2-Deoxy-3,5-di-O-toluoyl-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one

    CAS :

    6-(2-Deoxy-3,5-di-O-toluoyl-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a nucleoside analog that inhibits the activity of DNA polymerase and RNA polymerase. It has been shown to be active against human leukemia cells and is currently being used in clinical trials for cancer treatment. 6-(2-Deoxy-3,5-diOtoluoyl b D ribofuranosyl)-3,4 dihydro 8H pyrimido[4,5 c] [1,2]oxazin 7 one is a novel nucleoside analog that has been shown to be effective against both DNA and RNA viruses.

    Formule :C27H27N3O7
    Degré de pureté :Min. 95%
    Masse moléculaire :505.52 g/mol

    Ref: 3D-ND145588

    1g
    1.355,00€
    50mg
    305,00€
    100mg
    341,00€
    250mg
    586,00€
    500mg
    883,00€
  • 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine

    CAS :
    5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine is an antiviral and anticancer monophosphate nucleoside. It has been shown to be a potent inhibitor of HIV replication in vitro, with IC50 values of 0.5 μM for HIV-1 and 0.8 μM for HIV-2. 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine also inhibits the replication of herpes simplex virus type 1 (IC50 = 0.7 μM) and cytomegalovirus (IC50 = 2.6 μM). 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine was found to be more than 10 times as potent as adenosine in inhibiting DNA synthesis in human tumor cell lines, including leukemia cells, carcinoma cells,
    Formule :C13H14IN5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :447.19 g/mol

    Ref: 3D-NC05725

    5mg
    305,00€
    10mg
    312,00€
    25mg
    458,00€
  • 2'-Deoxycytidine-5'-carboxylic acid

    CAS :

    2'-Deoxycytidine-5'-carboxylic acid (2'-DC) is a modified nucleoside that has been used as an anticancer, antiviral, and synthetic agent. 2'-DC inhibits the synthesis of DNA by binding to the enzyme DNA polymerase. It also inhibits viral replication by inhibiting the activity of reverse transcriptase and can be used as a potential anti-HIV drug. In addition, 2'-DC has been shown to have cytotoxic effects against cancer cells in vitro. This compound is synthesized from cytidine 5-monophosphate and phosphoramidite reagents in high purity and quantity. The CAS number for this compound is 4603-72-9.

    Formule :C9H11N3O5
    Degré de pureté :Min. 95%
    Masse moléculaire :241.2 g/mol

    Ref: 3D-ND158446

    1mg
    1.540,00€
  • 5-Fluoro-2'-O-methyluridine

    CAS :
    5-Fluoro-2'-O-methyluridine is a nucleotide that can be used in the treatment of colorectal adenocarcinoma and other types of cancer. It inhibits the synthesis of DNA by blocking the activity of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. 5-Fluoro-2'-O-methyluridine has been shown to decrease the growth of human glioblastoma cells in cell culture and animal models. The effect is dose dependent and occurs through inhibition of RNA synthesis and protein synthesis, leading to cell death.
    Formule :C10H13FN2O6
    Degré de pureté :Min. 95%
    Masse moléculaire :276.22 g/mol

    Ref: 3D-NF06416

    1g
    3.554,00€
    25mg
    305,00€
    50mg
    459,00€
    100mg
    694,00€
    250mg
    1.240,00€
  • 2'/3'-O-(N-Methylanthraniloyl)-adenosine-5'-diphosphate triethylammonium salt

    CAS :
    Supplied as a 10mM solution (150uL).λmax 255 nm, ε 23.3 L mmol-1 cm-1Sold by weight of solid
    Formule :C18H22N6O11P2
    Degré de pureté :Min. 95%
    Masse moléculaire :560.35 g/mol

    Ref: 3D-NM29546

    800µg
    484,00€
  • 2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine


    2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside with anticancer and antiviral properties. It has been shown to inhibit replication of human immunodeficiency virus and herpes simplex virus type 1 in vitro. The drug also inhibits the growth of tumor cells in vitro. 2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is an analog of adenosine, which is phosphorylated by the enzyme ribonucleoside diphosphate kinase to form 2'-deoxyadenosine monophosphate, a common building block for DNA synthesis.
    Formule :C16H19N5O7
    Degré de pureté :Min. 95%
    Masse moléculaire :393.35 g/mol

    Ref: 3D-NA08320

    1g
    928,00€
    2g
    1.472,00€
    100mg
    305,00€
    250mg
    369,00€
    500mg
    574,00€