Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3
Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 is a novel nucleotide analogue that is synthesized from the corresponding phosphoramidite. It has antiviral activity and can be used as an analog of cytosine arabinoside for the treatment of herpes zoster. Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 has been shown to inhibit viral replication by interacting with DNA and RNA synthesis. This drug also inhibits DNA polymerase activity in vitro and blocks viral transcription. Cytarabine can be used in combination with other antiviral drugs such as acyclovir or ganciclovir.Degré de pureté :Min. 95%5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine
5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine is a nucleoside analog drug that has antiviral and anticancer properties. It is synthesized by the reaction of 5'-O-dimethoxytritylthymidine with 2,4,5,6-tetrahydropyrimidinone. This compound has been shown to be active in vitro against several viruses including herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1). The antiviral activity of 5'-O-DMT-N2-isobutyrylguanine is due to inhibition of viral DNA polymerase and/or virion assembly. It also inhibits tumor cell growth in vitro.Formule :C35H37N5O8Degré de pureté :Min. 95%Masse moléculaire :655.71 g/mol2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt
2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt is a nucleoside analog that inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. It has been shown to be effective against cancer cells in vitro and in vivo. Although it is not active against mycobacterium and other acid-fast bacteria, 2',3'-didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt has shown promising anticancer properties and may be useful for the treatment of leukemia, lymphoma, and breast cancer.Degré de pureté :Min. 95%8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate
CAS :8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate (8-AEACMP) is a structural analog of the purine nucleotide adenosine. It has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. 8-AEACMP blocks HIV transcription by binding to the cellular target, the enzyme ribonucleotide reductase. This binding prevents the formation of an enzyme-substrate complex that is required for DNA synthesis. 8-AEACMP binds to two sites on this enzyme: one site is at a catalytic site that is not involved in substrate binding, and the other site is at a regulatory site. The inhibitory effect of 8-AEACMP on HIV transcription results from its ability to bind at both sites simultaneously.Formule :C12H18N7O6PDegré de pureté :Min. 95%Masse moléculaire :387.29 g/mol2',3'-Dideoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :2',3'-Dideoxyguanosine-5'-triphosphate lithium salt (ddGTP) is a nucleotide analogue that inhibits the activity of DNA polymerase, RNA polymerase, and other enzymes. It has been shown to be an effective inhibitor of primary breast cancer cells in vitro. ddGTP is also a fluorescent compound with a light emission maximum at about 520 nm. The fluorescence intensity increases with increasing concentrations of ddGTP. This product is supplied as a 100mM aqueous solution containing ddGTP.Formule :C10H16N5O12P3Degré de pureté :Min. 95%Masse moléculaire :491.18 g/mol6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt
CAS :6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it canFormule :C17H16N5Na2O9PSDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :543.36 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-uridine
CAS :<p>4'-C-Azido-2'-deoxy-2'-fluoro-uridine is a novel nucleoside with antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine is activated by ribonucleoside kinase, which phosphorylates the 4'-C position on the sugar moiety to form the monophosphate. This drug has been shown to inhibit proliferation of human lymphoid leukemia cells in culture and to inhibit replication of HIV in cell culture. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine also inhibits herpes simplex virus type 1 (HSV1) replication in vitro.</p>Formule :C9H10FN5O5Degré de pureté :Min. 95%Masse moléculaire :287.2 g/mol8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine
CAS :8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is an anti-cancer, antiviral, and anticancer agent. It has shown anticancer activity in a number of animal models. This drug also inhibits the replication of DNA by inhibiting the synthesis of DNA precursors. 8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is synthesized from 2,6-diaminohexane and 1,3,5-triazine by reaction with formaldehyde and allyl bromide in the presence of potassium hydroxide. The product is purified by chromatography on silica gel using a mixture of chloroform/methanol (1:1) as eluent to yield a colorless liquid. The chemical structure is characterized by IR spectroscopy and mass spectrometry.Formule :C16H22N6O5Degré de pureté :Min. 95%Masse moléculaire :378.38 g/mol1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine
CAS :1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine is a nucleoside that can be used as a reagent in the synthesis of oligodeoxynucleotides. It has been shown to bind to DNA, and it is phosphoramidite monomer for solid phase synthesis of oligodeoxynucleotides. It is also a nonamer, octamer, and dinucleoside. 1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine binds to the receptor protein and has been shown to have efficiencies as high as 45%.Formule :C31H32N2O7Degré de pureté :Min. 95%Masse moléculaire :544.6 g/molAdenosine 5'-triphosphate potassium salt
CAS :<p>Adenosine 5'-triphosphate potassium salt is a membrane potential-sensitive fluorescent probe. It has been used to measure the intensity of light exposure and the depolarising effects of activation in sarcoplasmic reticulum vesicles. Adenosine 5'-triphosphate potassium salt has also been used to measure the activity of cyclic nucleotide phosphodiesterases, which are enzymes that regulate the breakdown of cAMP and cGMP. The fluorescence of adenosine 5'-triphosphate potassium salt increases with increased concentrations of cyclic nucleotide phosphodiesterase, indicating that it is an effective indicator for measuring these types of enzymes in biological assays.</p>Formule :C10H14K2N5O13P3Degré de pureté :Min. 95%Masse moléculaire :583.36 g/molUridine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS :Mixture of Rp and Sp isomers.Formule :C9H15N2O14P3SDegré de pureté :Min. 95%Masse moléculaire :500.21 g/mol2'-Deoxyguanosine-5'-diphosphate disodium salt
CAS :2'-Deoxyguanosine-5'-diphosphate disodium salt is a marine metabolite that is used as a chemotactic agent for bacteria. It functions by stimulating motility and chemotaxis in marine bacteria. This metabolite is derived from the sulfur oxidation pathway and it has been shown to have genetic regulatory functions in the symbiosis of roseobacters. 2'-Deoxyguanosine-5'-diphosphate disodium salt interacts with the enteric bacteria clade, which may be due to its ability to cycle between sulfur and oxygen environments.Formule :C10H13N5O10P2·2NaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :471.16 g/mol5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt
<p>5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt is an antiviral drug, which is a synthetic nucleoside analogue of cytidine. It inhibits the synthesis of viral DNA by competing with deoxycytidine triphosphate for incorporation into nascent DNA chains. This antiviral agent has been shown to be effective against HSV-1 and HIV-1 in vitro.</p>Degré de pureté :Min. 95%2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole
CAS :<p>2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside with anticancer activity. It is an activator of phosphoramidite synthesis and has been shown to be an antiviral agent against herpes simplex virus type 1 (HSV-1). 2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside that can be used for the synthesis of DNA or RNA. This product is offered in high purity, diphosphate form, at a monophosphate level.</p>Formule :C34H32N2O7Degré de pureté :Min. 95%Masse moléculaire :580.63 g/molN2-Carbamoylthreonyl-2'-deoxyguanosine
N2-Carbamoylthreonyl-2'-deoxyguanosine is a phosphoramidite monophosphate that is used in the synthesis of DNA. It has antiviral and anticancer properties. N2-Carbamoylthreonyl-2'-deoxyguanosine is synthesized by modifying the nucleoside thymidine, which contains a 2'-deoxyribose sugar and an amino sugar, with carbamate linkages at the 2' position. This modification stabilizes the sugar moiety, preventing it from undergoing hydrolysis to form ribose and deoxyribose. The stability of the modified nucleoside allows for increased solubility in aqueous solution and increased resistance to degradation by nucleases. N2-Carbamoylthreonyl-2'-deoxyguanosine also has high purity and quality as well as novel modifications not found in other DNA building blocksDegré de pureté :Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS :<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel modified nucleoside that is an activator of ribonucleosides. It has antiviral and anticancer activities, in addition to its potential as a DNA polymerase inhibitor. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is chemically synthesized with high purity and can be used for the synthesis of phosphoramidites for DNA synthesis. This compound also has the CAS number 12105885 3 and can be found in monophosphate form.</p>Formule :C38H47N3O8SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :701.88 g/mol2'-Deoxy-5-fluorocytidine 5'-monophosphate
CAS :<p>2'-Deoxy-5-fluorocytidine 5'-monophosphate is a nucleotide that is synthesized by the enzyme cytidine deaminase. It is used as a diagnostic agent in the detection of infectious diseases such as HIV, Mycobacterium tuberculosis, and cytomegalovirus (CMV). 2'-Deoxy-5-fluorocytidine 5'-monophosphate inhibits DNA synthesis by blocking the incorporation of deoxycytidylate into DNA. The compound is also an inhibitor of collagen synthesis in tissues and cells. Hydrogen bonds between this compound and its target enzymes are thought to be important for its inhibitory effects.</p>Formule :C9H13FN3O7PDegré de pureté :Min. 95%Masse moléculaire :325.19 g/mol4'-C-Azido-3'-deoxy-3'-fluorocytidine
CAS :<p>4'-C-Azido-3'-deoxy-3'-fluorocytidine is an antiviral, anticancer, and nucleoside phosphoramidite. It is a novel modified nucleoside that has antiviral, anticancer, and DNA modifying properties. 4'-C-Azido-3'-deoxy-3'-fluorocytidine has been shown to be an activator of the polymerase chain reaction (PCR). This product has high purity with no detectable impurities. The CAS number for this compound is 1145869-46-0. This product is available in bulk quantities.</p>Formule :C9H11FN6O4Degré de pureté :Min. 95%Masse moléculaire :286.22 g/mol2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt - 100mM aqueous solution
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is a novel, synthetic nucleoside. It is a monophosphate and can be activated with adenosine triphosphate to form the diphosphate. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is also an antiviral agent that inhibits viral RNA synthesis. The anticancer activity of 2'-deoxy-2'-fluoroguanosine-5' triphosphate sodium salt has not been studied in detail.Formule :C10H15FN5O13P3·NaDegré de pureté :Min. 95%Masse moléculaire :548.16 g/molPyrrolo-2’-deoxycytidine 3’-CE phosphoramidite
CAS :A fluorescent analogue of deoxycytidine. Used for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Emission max is at 473nm.Formule :C42H50N5O7PDegré de pureté :Min. 95%Masse moléculaire :767.8 g/mol
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