
Nucléosides
3569 produits trouvés pour "Nucléosides"
5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine
CAS :5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine is an anticancer, antiviral, and phosphoramidite DNA synthesis reagent that is modified by the addition of a trifluoroacetamide group. It has been shown to activate monophosphate nucleotides and nucleosides to their corresponding diphosphates and deoxyribonucleosides. 5-[N(2-Trifluoroacetamido)ethyl]-3-(E)-acrylamido]-2-deoxyuridine is synthesized from 2-deoxyuridine which is derived from uracil and phenol. This novel chemical substance has shown promising results in preclinical testing against human cancers and viral infections.Formule :C16H19F3N4O7Degré de pureté :Min. 95%Masse moléculaire :436.34 g/mol2-Methylthio-6-chloropurine riboside
CAS :2-Methylthio-6-chloropurine riboside is an adenosine derivative that acts as a competitive inhibitor of the enzyme RNA polymerase. It is used in the process of translation to inhibit protein synthesis. 2-Methylthio-6-chloropurine riboside is synthesized by reacting 2-methylthioadenosine with 6-chloropurine riboside and then phosphoramidite chemistry.Formule :C12H15CIN4O5SDegré de pureté :Min. 95%Masse moléculaire :466.25 g/mol6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester
CAS :6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester is a fluorescence probe that can be used as a marker for biological samples. It is minimally toxic and stable in vitro, and can be used to measure the protein content of cells. This compound has been used in vitro methods to study the effects of environmental factors on cellular metabolism by measuring the amount of ATP in 3T3-L1 preadipocytes. 6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester has also been used to measure the effectiveness of wastewater treatment processes by analyzing the fluorescence intensity of cells using confocal microscopy. It has also been shown to have an effect on hypersensitivity syndrome and infectious diseases.Formule :C29H19NO11Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :557.46 g/molEmtricitabine-d2,15N
CAS :Emtricitabine-d2,15N is a labelled version of emtricitabine. It is a nucleoside reverse transcriptase inhibitor that inhibits the HIV-1 virus by blocking the activity of the enzyme needed to convert RNA into DNA. This drug also offers long-term efficacy and can be used in combination with other antiretroviral agents including tenofovir alafenamide hemifumarate (TAF) and tenofovir disoproxil fumarate (TDF). The addition of TAF or TDF to emtricitabine-d2,15N provides an active antiretroviral therapy for HIV/AIDS patients. Emtricitabine-d2,15N has shown to reduce viral load significantly in people taking it as part of their treatment regimen.
Formule :C8D10FN3O3SDegré de pureté :Min. 95%Masse moléculaire :257.3 g/mol1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione
CAS :1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is a novel nucleoside that is synthesized from 5-(3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzyl)pyrimidine and dimethoxytrityl chloride. This compound has antiviral and anticancer properties. It can inhibit the replication of DNA by binding to the 3' hydroxyl group of the deoxyribonucleotide triphosphate. It also inhibits cancer cell growth by inhibiting RNA synthesis and protein synthesis. 1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3 , 2]dDegré de pureté :Min. 95%2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS :2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. It is a synthetic nucleoside analogue with antiviral activity against herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein Barr virus, and human immunodeficiency virus type 1. This compound is also used as a building block in the preparation of phosphoramidites for chemical synthesis of deoxyribonucleosides. 2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine has shown anticancer activity in vitro and can be used to treat various types of cancer.Formule :C10H11F2N5O3Degré de pureté :Min. 95%Masse moléculaire :287.22 g/mol2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
CAS :2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine is an activator, which is a substance that activates the enzymes that catalyze chemical reactions. It is a novel material with high purity and high quality. The activator can be used in the synthesis of ribonucleosides, deoxyribonucleosides, nucleosides, and phosphoramidites. 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine has been found to have anticancer and antiviral activities.Degré de pureté :Min. 95%N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl) -2'-deoxyadenosine
CAS :N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a versatile nucleoside building block.Formule :C38H35N5O6Degré de pureté :Min. 98 Area-%Masse moléculaire :657.71 g/mol3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine
CAS :3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine is a modified nucleoside that has antiviral and anticancer properties. It is a synthetic nucleotide with a novel structure that can be phosphorylated to form the corresponding diphosphate, monophosphate, or phosphoramidites. 3N-(2,4-Dimethylbenzyl)-1-(5-O-DMT (3'-O-[(dimethylamino)methyl]oxime)-2'-deoxyribofuranosyl)thymidine is used as an antiviral agent against HIV and other retroviruses.Formule :C46H45N3O13SDegré de pureté :Min. 95%Masse moléculaire :879.93 g/mol2'-Deoxy-5'-O-p-toluenesulfonyluridine
CAS :2'-Deoxy-5'-O-p-toluenesulfonyluridine is a nucleoside that is modified with a p-toluenesulfonyl group on the 2' position. This compound has been shown to be an activator of phosphoramidites. It is also used as an anticancer drug, antiviral agent, and in the synthesis of ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-p-toluenesulfonyluridine is typically used as a building block for RNA or DNA synthesis. This compound can also be used in the preparation of aminoglycoside antibiotics, as well as for the treatment of cancerous tumors.
Formule :C16H18N2O7SDegré de pureté :Min. 95%Masse moléculaire :382.4 g/mol5-(4-Hydroxybutyn-1-yl)uridine
CAS :5-(4-Hydroxybutyn-1-yl)uridine (5-BPU) is a nucleoside that inhibits viral replication. It is synthesized by the phosphoramidite method and modified to produce a 5-(4-hydroxybutyn-1-yl)uridine diphosphate (5-BPUDP). 5-BPUDP can be phosphorylated to form 5-(4-hydoxybutyn-1-yl)uridine monophosphate (5-BPUMP), which is more active than 5-(4-hydoxybutyn-1 -yl)uridine diphosphate. The antiviral activity of this drug has been demonstrated in vitro using human T lymphocytes, Epstein Barr virus, and herpes simplex virus type 1. It has also shown anticancer activity against leukemia cells in mice and rats.Formule :C13H16N2O7Degré de pureté :Min. 95%Masse moléculaire :312.28 g/mol(4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
The phosphoramidite monophosphate compound is a synthetic nucleotide analogue that has antiviral and anticancer properties. The chemical formula of the compound is (4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate. This chemical can be used as a building block in DNA synthesis to produce deoxyribonucleosides and activate ribonucleoside phosphates to produce ribonucleosides. It has a CAS number of 90533-20-0.Formule :C26H37Cl2N6O9PDegré de pureté :Min. 95%Couleur et forme :Pale yellow oilMasse moléculaire :679.49 g/mol5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine
CAS :5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a novel antiviral monophosphate nucleoside. It inhibits viral DNA synthesis by competing with natural deoxyribonucleosides in the cell. 5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a high purity, modified nucleoside that has been synthesized by chemical phosphoramidite chemistry and modified to allow for efficient polymerase chain reactions. This product has been tested as an anticancer agent in vitro.Formule :C33H36N4O6Degré de pureté :Min. 95%Masse moléculaire :584.66 g/molPseudoisocytidine hydrochloride
CAS :Pseudoisocytidine is a nucleoside analogue that inhibits bacterial growth by binding to the ribosomal RNA of bacteria. Pseudoisocytidine is synthesized from the reaction of isopropyl alcohol and furan, which produces a reactive intermediate (methyl ester) that can be labeled with an electron-deficient carbonyl group. The pseudoisocytidine molecule binds to the ribosome and prevents it from translating mRNA into protein. This leads to inhibition of bacterial growth. Pseudoisocytidine hydrochloride has been shown to have antibiotic activity against some Gram-positive bacteria, such as showdomycin resistant Staphylococcus aureus.
Formule :C9H13N3O5·HClDegré de pureté :Min. 95%Masse moléculaire :279.68 g/molPyrimidine-5-carboxamidine hydrochloride
CAS :Pyrimidine-5-carboxamidine hydrochloride (GC) is a guanosine analog that inhibits bacterial growth by binding to the anticodon region of ribosomes. GC has been shown to bind to the replicons of many organisms, including bacteria, and inhibit the formation of mRNA from DNA. This drug also inhibits methyltransferase, which prevents transfer RNA from being modified with methionine. GC may be used in research for eukaryotes and deamination reactions in trna modification.Formule :C5H6N4·HClDegré de pureté :Min. 95%Masse moléculaire :158.59 g/mol2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine
CAS :2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a novel nucleoside analogue that inhibits the proliferation of cancer cells. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides and thereby prevents viral replication. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine has antiviral activity against influenza A virus and herpes simplex virus type 1 (HSV-1) in cell culture. This drug also has an inhibitory effect on the DNA polymerases and other enzymes involved in DNA synthesis. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a high quality product with high purity, CAS No. 1000203-40-6.Degré de pureté :Min. 95%3'-Deoxy-3'-fluoro-5'-O-tritylthymidine
CAS :3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.Formule :C29H27FN2O4Degré de pureté :Min. 95%Masse moléculaire :486.53 g/molN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS :N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a nucleoside analog that is used as an antiviral and anticancer drug. It is also known to be an activator of the immune system. N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to inhibit viral DNA replication, induce apoptosis, and inhibit tumor growth. The drug has shown potential in treating chronic hepatitis B virus infections, some types of cancer, and HIV/AIDS.Formule :C34H37N3O8Degré de pureté :Min. 95%Masse moléculaire :615.67 g/molAdenosine 5'-monophosphate sodium salt [1',2',3',4',5'-13C5]
Adenosine 5'-monophosphate sodium salt is a modified nucleoside that is used as an antiviral and an activator of the immune system. It also has been shown to have anti-inflammatory properties. Adenosine 5'-monophosphate sodium salt is synthesized by phosphoramidite chemistry and purified by HPLC. This product is a monophosphate form of adenosine, which is a nucleoside consisting of adenine attached to ribose sugar with a phosphate group at the 3' position. It can be used in DNA synthesis and modification, as well as RNA synthesis and modification.Degré de pureté :Min. 95%2'-Deoxy- N, N- dimethyl-adenosine
CAS :2'-Deoxy-N, N-Dimethyl-Adenosine is a nucleoside that is phosphorylated to 2'-deoxy-N, N-dimethyl-adenosyl monophosphate. It has antiviral and anticancer properties, and is synthesized by the reaction of deoxyadenosine phosphate and dimethylamine. This product is a novel nucleoside with modified phosphate groups. The synthesis of this nucleoside has been patented.
Formule :C12H17N5O3Degré de pureté :Min. 95%Masse moléculaire :279.3 g/mol
