Nucléosides

Emtricitabine is a synthetic nucleoside analog of cytidine. It is used in the treatment of HIV infection and hepatitis B virus infection. Emtricitabine binds to human DNA polymerase, preventing the incorporation of viral DNA into the host cell's genome. This prevents the virus from multiplying and reproducing, thereby inhibiting the spread of HIV in humans. The drug has been shown to inhibit replication at all stages of HIV-1, including reverse transcription and integration into host cell DNA. Emtricitabine also inhibits replication of other viruses such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV). Emtricitabine is a prodrug that must be activated by phosphorylation before it can be incorporated into DNA. This activation requires tenofovir alafenamide hemifumarate as an activator, which is an experimental drug with improved bioavailability, reduced renal clearance, and

Fluorescein-dt cep is a monophosphate nucleoside analog that is modified with an activated ester group. It is used as a prodrug for the treatment of influenza in humans. Fluorescein-dt cep has antiviral activity, which may be due to its ability to inhibit viral RNA synthesis. This agent also has anticancer activity and has been shown to kill leukemia cells by interfering with DNA synthesis. The chemical name for fluorescein-dt cep is 1-(2,6-dichloro-4-(5,7-dimethoxy-4-methylpyridiniumyl)phenyl)cytosine monophosphate. Fluorescein-dt cep is also known by the following synonyms: 1-(2,6-Dichloro-4-(5,7-dimethoxyquinoliniumyl)phenyl)-1H-[1,3]diox

Thymidine 5'-triphosphate-3'-monophosphate is a nucleoside that is used in the synthesis of DNA. It is an activator of anticancer drugs, and has been shown to have antiviral properties. Thymidine 5'-triphosphate-3'-monophosphate can be used for the treatment of viral diseases such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and human immunodeficiency virus (HIV) infection. This nucleoside also plays a role in the prevention of tumor growth and metastasis because it inhibits DNA synthesis.

<p>6-Chloropurine-9-b-D-glucoside is a nucleoside that belongs to the family of modified nucleosides. It is used as an activator and a phosphoramidate in the synthesis of oligonucleotides. 6-Chloropurine-9-b-D-glucoside is also used in anticancer therapy because it inhibits DNA, RNA, and protein synthesis. 6CPG has antiviral activity against herpes virus and other viruses. This compound has been shown to have antiinflammatory activities by inhibiting the production of prostaglandins. 6CPG is also classified as a carcinogen by the International Agency for Research on Cancer (IARC).</p>

<p>2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.</p>

4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral activity. It is activated by the addition of a DMT group to its 5' end and has an anticancer effect. The monophosphate form of 4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite has been shown to inhibit viral DNA synthesis in vitro and to be cytotoxic against human cancer cell lines. 4-(2-Cyanoethylthio)-5'-O-DMT- thymidine 3'-CE phosphoramidite is a high quality, high purity product that can be used as a nucleoside or nucleotide in anticancer drugs.

<p>N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel, modified, activator with antiviral and anticancer properties. It is the monophosphate of the acetylated 2'-deoxyadenosine 3'-cyanoethylphosphoramidite and has been shown to be effective in inhibiting DNA synthesis in cell cultures. This product is synthesized using high purity reagents and purification techniques.</p>

6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it can

<p>TFA-ap-dU is a modified, ribonucleosides that are used in DNA synthesis. The polymerase chain reaction (PCR) technique can be used to generate a large number of copies of a specific sequence of nucleotides from the original DNA template. This product is used for antiviral and anticancer research. TFA-ap-dU has been shown to be effective against Hepatitis B virus and Human Immunodeficiency Virus (HIV). It is also an activator of DNA and RNA synthesis.</p>

<p>2’-Chloro-2’-deoxyadenosine (2CDA) is a synthetic nucleoside analogue that is used as an antineoplastic agent for the treatment of non-Hodgkin lymphoma and histiocytic lymphoma. It is typically used in combination with other cytotoxic drugs. 2CDA has been shown to be effective against resistant tumor cell lines and has been used to treat patients with metastatic breast cancer, Hodgkin lymphoma, and multiple myeloma. The drug can cause thrombocytopenia, which may be due to its effects on platelets or bone marrow cells. Other toxicities include bone marrow suppression, nausea, vomiting, diarrhea, anorexia, and liver damage. Patients who are at risk for these toxicities should be closely monitored.</p>

<p>2-Chloro-3-deazaadenosine is an antiviral drug that inhibits the synthesis of DNA by acting as a competitive inhibitor for adenosine. It has been shown to be effective in the treatment of hepatitis B virus and herpes simplex virus infections. 2-Chloro-3-deazaadenosine prevents the incorporation of the natural nucleoside adenosine into DNA, which leads to inhibition of viral replication and cell division. This drug also has been shown to inactivate liver cells in bovines, which may account for its toxicity. The synthesis of 2-chloroadenosine is difficult and laborious due to its glycosylation, making it more expensive than other analogues that are more easily synthesized.</p>

N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is an activator of DNA polymerase. It has been shown to be a potent inhibitor of viral replication and an anticancer agent in vitro. The compound has also been shown to inhibit the growth of tumor cells in vivo. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue that has not been previously reported.

5'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is a component of DNA. 5'-O-Benzoyl-2'-deoxyuridine is used as an antiviral agent and for the treatment of some cancers, including lymphomas, leukemia, and certain types of solid tumors. It has also been shown to be effective in the treatment of hepatitis B virus infection. This compound inhibits viral replication by competing with natural nucleosides for incorporation into DNA and RNA. 5'-O-Benzoyl-2'-deoxyuridine binds to double helix DNA at the groove between adenine and thymine bases and prevents further binding of nucleotides to this site. It also inhibits viral DNA synthesis by preventing conversion of ribonucleotides to deoxynucleosides. This drug is not active against bacteria or fungi; however, it can cause serious side effects such as pancreatitis and liver toxicity.

Carbocyclic analog of cytidine

<p>2-(Aminomethyl)pyrimidine oxalate is a substance that can be found in cicer arietinum. This compound has been shown to be tumorigenic, and it is hypothesized that the tumorigenicity of this compound is due to its ability to recombine with DNA and expressed genes, which may lead to the development of tumors. 2-(Aminomethyl)pyrimidine oxalate has been shown to activate translation of genes that are involved in tumorigenesis. The gene product which has been identified as being activated by 2-(aminomethyl)pyrimidine oxalate is called rhizogenes. Rhizogenes have been shown to have virulent phenotypes when exposed to cicer arietinum. With all these properties, it is believed that 2-(aminomethyl)pyrimidine oxalate may cause cancer or other harmful effects on organisms.br&gt;<br>br&gt;</p>

Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite is a potent inhibitor that targets human immunodeficiency virus (HIV) and cancer. It acts as an analog of substrates for human plasma membrane kinases, which are essential for the replication of HIV. Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite has been shown to inhibit lung metastasis in mice, indicating its potential therapeutic use against cancer. This compound also exhibits inhibitory activities against Escherichia coli alkaline phosphatase and other enzymes, suggesting its pharmacological activity may extend beyond HIV and cancer treatment. Overall, Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite is a promising inhibitor with potential applications in multiple fields.

9-Deaza-2'-deoxyguanosine is a novel synthetic nucleoside that activates the ribonucleotide reductase enzyme. The activation of this enzyme was found to be dependent on the presence of diphosphate, which is a cofactor for this enzyme. 9-Deaza-2'-deoxyguanosine has been shown to inhibit the growth of cells in culture and to induce apoptosis. It also inhibits viral replication by interfering with the synthesis of viral DNA. In addition, 9-Deaza-2'-deoxyguanosine can inhibit tumor cell proliferation and promote differentiation in vitro.

3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester (AZT) is a novel nucleoside compound that is a phosphoramidite. AZT has antiviral activity against various DNA and RNA viruses, including HIV. It is also effective in the treatment of cancer. AZT inhibits viral replication by competitively inhibiting the incorporation of diphosphate into viral DNA or RNA. This process prevents the synthesis of new virus particles and the spread of infection to healthy cells. In addition, AZT may inhibit tumor growth by interfering with cell division and DNA synthesis.

(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-

<p>Please enquire for more information about 5-Hydroxymethyl-dc ce-phosphoramidite (hmdc) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>