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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • 8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS :
    8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.
    Formule :C10H17N6O13P3·xNa
    Degré de pureté :Min. 95%
    Masse moléculaire :522.2 g/mol

    Ref: 3D-NA12011

    1mg
    353,00€
    2mg
    497,00€
    5mg
    872,00€
    10mg
    1.184,00€
    25mg
    1.973,00€
  • 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine

    CAS :
    4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.
    Formule :C29H56N4O4Si3
    Degré de pureté :Min. 95%
    Masse moléculaire :609.04 g/mol

    Ref: 3D-NA04493

    5mg
    497,00€
    10mg
    768,00€
    25mg
    1.118,00€
  • 5-Azauridine

    CAS :
    <p>5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.</p>
    Formule :C8H11N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :245.19 g/mol

    Ref: 3D-NA145615

    100mg
    1.629,00€
  • N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite

    CAS :
    <p>N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is an antiviral agent that inhibits the activity of viral DNA polymerase. This chemical has been shown to be effective against herpes virus, pox virus and HIV. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is a novel nucleotide analogue that contains a modified deoxyribose sugar backbone. It has been shown to be active against cancer cells in vitro, but not in vivo.</p>
    Formule :C47H51FN7O7P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :875.95 g/mol

    Ref: 3D-PB08457

    25mg
    218,00€
    50mg
    341,00€
    100mg
    486,00€
    250mg
    863,00€
    500mg
    1.085,00€
  • N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite


    <p>N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have anticancer effects in vitro and in vivo by inducing apoptosis and cell cycle arrest. This compound has also been shown to be more potent than other nucleosides, such as cytidine 5'-diphosphate (CDP) or cytidine 5'-monophosphate (CMP). This chemical is not yet commercially available but can be custom synthesized for research purposes.</p>
    Formule :C52H64N5O10P
    Degré de pureté :Min. 95%
    Masse moléculaire :950.07 g/mol

    Ref: 3D-PB63476

    1g
    329,00€
    2g
    478,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    300,00€
  • N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt


    <p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt is a novel, modified nucleoside analogue that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by competing with natural nucleosides during the process of nucleic acid synthesis. The drug binds to the enzyme ribonucleotide reductase, which is essential for DNA synthesis. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt has been shown to be effective in treating patients with cancer.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-PB158800

    1g
    300,00€
  • 2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine


    <p>2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine is a monophosphate nucleotide, which is an antiviral agent. It is a novel, high quality and high purity compound. The CAS number for 2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine is 69681-06-8. It has antiviral activity against the herpes simplex virus type 1 (HSV1) and Epstein Barr virus (EBV). This drug also inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. This product can be used in research to synthesize phosphoramidites, activator molecules, and nucleosides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND145914

    1g
    300,00€
    2g
    315,00€
    5g
    598,00€
    10g
    1.067,00€
  • 2'-Deoxyadenosine-5'-carboxylic acid

    CAS :
    <p>dA oxidised at the 5'-position.</p>
    Formule :C10H11N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :265.23 g/mol

    Ref: 3D-ND158443

    ne
    À demander
  • O6-Benzyl-N2,3-etheno guanosine

    CAS :
    <p>O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.</p>
    Formule :C19H19N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :397.38 g/mol

    Ref: 3D-NB16629

    5mg
    303,00€
    10mg
    401,00€
    25mg
    650,00€
    50mg
    1.055,00€
    100mg
    1.916,00€
  • N1-Methyladenosine hydroiodide

    CAS :
    <p>N1-Methyladenosine hydroiodide is a novel nucleoside analogue that inhibits viral replication by preventing the formation of viral DNA. It also inhibits the growth of cancer cells and is used as an anticancer drug. N1-Methyladenosine hydroiodide has been shown to be an activator of RNA polymerase II, increasing the production of messenger RNA (mRNA) in human cells. The phosphoramidite form of this compound is used for the synthesis of oligodeoxyribonucleotides, which are chemically modified in order to improve their stability and inhibit degradation by nucleases. N1-Methyladenosine hydroiodide is highly pure and has CAS No. 34308-25-3.</p>
    Formule :C11H15N5O4·HI
    Degré de pureté :Min. 95%
    Masse moléculaire :409.18 g/mol

    Ref: 3D-NM08030

    50mg
    303,00€
    250mg
    416,00€
  • Thymidine-3',5'-tetrabenzyldiphosphate


    <p>Thymidine-3',5'-tetrabenzyldiphosphate is a monophosphate analog of thymidine. It has been used as a building block for the synthesis of DNA, RNA, and phosphoramidites. Thymidine-3',5'-tetrabenzyldiphosphate is a novel nucleoside compound that has been shown to have anticancer and antiviral activities. This product is intended for research purposes only.</p>
    Formule :C38H40N2O11P2
    Degré de pureté :Min. 95%
    Masse moléculaire :762.68 g/mol

    Ref: 3D-NT07361

    5mg
    303,00€
    10mg
    309,00€
    25mg
    589,00€
    50mg
    1.013,00€
    100mg
    1.710,00€
  • 5-Isopropyl-2'-deoxyuridine

    CAS :
    <p>5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.</p>
    Formule :C12H18N2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :270.28 g/mol

    Ref: 3D-NI16765

    1mg
    341,00€
    2mg
    486,00€
    5mg
    921,00€
    10mg
    1.518,00€
    25mg
    2.324,00€
  • Uridine-15N2

    CAS :
    <p>Uridine-15N2 is a novel nucleoside that has antiviral, anticancer and antifungal effects. It has been shown to inhibit the growth of tumor cells by blocking the synthesis of DNA and RNA. Uridine-15N2 is synthesized from uridine-5N2 and 15N2 gas. This product is used in molecular biology research as a substrate for DNA polymerase, to study the enzymatic process of DNA replication. It can also be used as an activator for ribonuclesides or deoxyribonucleosides in organic synthesis. Uridine-15N2 is soluble in water and has a high purity.</p>
    Formule :C9H12N2O6
    Degré de pureté :Min. 95%
    Masse moléculaire :244.20 g/mol

    Ref: 3D-SDA48768

    5mg
    817,00€
    10mg
    1.232,00€
    25mg
    1.957,00€
    50mg
    3.130,00€
  • O6-Benzyl guanosine

    CAS :
    <p>O6-Benzyl guanosine is a polymerized compound that has been shown to have anticancer efficacy. It has been tested in mice with medulloblastoma, a type of brain tumor, and in rats with breast cancer. O6-Benzyl guanosine was found to be hydrophobic and bound to the methyltransferase enzyme, which resulted in the inhibition of DNA synthesis. The polymerized compound is able to form conjugates with other molecules such as iron oxide nanoparticles or hydrazone derivatives, which can be used for treatments that involve bioconjugate chemistry.</p>
    Formule :C17H19N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :373.36 g/mol

    Ref: 3D-NB16621

    10mg
    381,00€
    25mg
    523,00€
    50mg
    806,00€
  • 2'-Deoxyxanthosine 5'-monophosphate

    CAS :
    <p>2'-Deoxyxanthosine 5'-monophosphate is a nucleoside which is an activator of the DNA polymerase. It has antiviral activity and is used in the synthesis of oligonucleotides. 2'-Deoxyxanthosine 5'-monophosphate is also used as a phosphoramidite in the chemical synthesis of DNA, and can be modified with fluorine or other atoms to form synthetic analogues.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND168482

    10mg
    4.452,00€
  • 5'-O-DMT-inosine

    CAS :
    <p>5'-O-DMT-inosine is a novel monophosphate nucleotide analogue. It is modified by the attachment of an aminooxy group to the 5' position of the pentose. This modification prevents ribonucleotide reductase from converting it into deoxyribonucleotides, which are then incorporated into DNA. 5'-O-DMT-inosine has been shown to be cytotoxic in human leukemia cells due to its ability to inhibit the synthesis of DNA and RNA.</p>
    Formule :C31H30N4O7
    Degré de pureté :Min. 95%
    Masse moléculaire :570.59 g/mol

    Ref: 3D-ND57511

    5g
    303,00€
    10g
    394,00€
    25g
    701,00€
  • 2',5'-Bis-O-(triphenylmethyl)uridine

    CAS :
    <p>2',5'-Bis-O-(triphenylmethyl)uridine is a synthetic nucleoside that is used in the treatment of leukemia. It is used as an analogue of uridine and guanosine, and is converted to these compounds by decarboxylase enzymes. 2',5'-Bis-O-(triphenylmethyl)uridine has been shown to inhibit the proliferation of L1210 cells in vitro and in vivo, but not normal cells. 2',5'-Bis-O-(triphenylmethyl)uridine also inhibits DNA synthesis by inhibiting the enzyme hydroxylase and carboxylate, which are involved in purine metabolism. This drug binds to the ribonucleotide reductase enzyme and blocks its activity, thereby inhibiting RNA synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB144784

    25mg
    303,00€
    50mg
    362,00€
    100mg
    516,00€
  • 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite


    <p>This is a phosphoramidite that is used in the synthesis of DNA. The chemical name for this compound is 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite. This compound has been shown to be an anticancer drug and has high purity, high quality, and novel properties.</p>
    Formule :C52H62N7O10P
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :976.09 g/mol

    Ref: 3D-PD09185

    1g
    329,00€
    2g
    502,00€
    5g
    962,00€
    500mg
    300,00€
  • 2'-Deoxy-N3-methylcytidine hydroiodide salt

    CAS :
    <p>2'-Deoxy-N3-methylcytidine hydroiodide salt is a nucleoside and phosphoramidite. It is used as an anticancer agent that inhibits DNA synthesis. It also has antiviral and antitumor effects. The chemical name for 2'-deoxy-N3-methylcytidine hydroiodide salt is 2'-deoxy-N3-methylcytidine, monophosphate salt with hydroiodic acid. This drug does not have a CAS number because it's not commercially available.</p>
    Formule :C10H17N3O4·HI
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :371.17 g/mol

    Ref: 3D-ND06231

    10mg
    279,00€
    20mg
    403,00€
    50mg
    690,00€
    100mg
    1.005,00€
    250mg
    1.822,00€
  • 2-Methylsulfanyl-4-phenylpyrimidine

    CAS :
    <p>2-Methylsulfanyl-4-phenylpyrimidine is a heterocyclic compound that has been shown to be an effective anti-malarial agent. The drug inhibits the growth of malaria parasites by binding to the parasite's DNA and preventing its replication. 2-Methylsulfanyl-4-phenylpyrimidine also recycles the monocyclic pyrimidines, which are nucleophiles, and therefore can be used as a precursor for other drugs.<br>2-Methylsulfanyl-4-phenylpyrimidine is not very soluble in water but is soluble in organic solvents such as ethanol, propylene glycol, or acetone. It has also been found to form stable salts with perchlorate and guanidine.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM44261

    1g
    793,00€
    100mg
    303,00€
    250mg
    373,00€
    500mg
    526,00€