Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-Azido-2'-deoxyadenosine
CAS :<p>2'-Azido-2'-deoxyadenosine is a synthetic nucleoside analog of adenosine in which the 2'-hydroxyl group of the ribose sugar is replaced by an azido group (–N₃), and the 3'- and 5'-hydroxyl groups remain intact. This modification confers unique chemical properties, including the ability to participate in bioorthogonal "click" chemistry reactions, particularly azide-alkyne cycloadditions, making it useful for labeling and tracking nucleic acids in biochemical studies. Additionally, the azido substitution can influence enzymatic recognition and incorporation by polymerases, allowing its use in studying nucleic acid metabolism, drug design, and therapeutic nucleoside analog development.</p>Formule :C10H12N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :292.25 g/mol2'-Deoxyadenosine-5'-monophosphate disodium salt
CAS :2'-Deoxyadenosine-5'-monophosphate disodium salt (DAP) is a white crystalline powder. It is soluble in water and insoluble in ethanol. DAP can be neutralised by aqueous solutions of hydroxide, such as sodium hydroxide or ammonium hydroxide. DAP is also reactive with aluminium oxide, which can be used for drying the compound to form anhydrous particles. DAP reacts with chloride ions to form 2',3'-diacetylpyridine-5'-diphosphate dibasic chloride, which has been shown to inhibit bacterial growth and act as an antibacterial agent. Autoclaving may be required for preparation of this drug due to its sensitivity to heat energy.Formule :C10H12N5Na2O6PDegré de pureté :Min. 99 Area-%Couleur et forme :White PowderMasse moléculaire :375.19 g/mol(R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine
CAS :<p>(R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine is a nucleoside monophosphate. It has been shown to be an activator of the enzyme adenylate cyclase, which converts ATP into cyclic AMP, a second messenger in cell signaling. (R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine does not have anticancer properties and does not inhibit the production of ribonucleotides or deoxyribonucleotides. This compound is synthesized using novel methods and is of high purity and quality.</p>Formule :C10H12N5Na3O9P2SDegré de pureté :Min. 95%Masse moléculaire :509.21 g/mol8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt
CAS :Activator of cGMP-dependent protein kinasesFormule :C10H10BrN5NaO7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :446.08 g/mol(4-N,N-(Dipropyl-1,1-diido-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
This is an activator, CAS No. is not available, Anticancer, monophosphate, Deoxyribonucleosides, Novel, Synthetic, High purity, High quality, Modified. It is a nucleoside phosphoramidite that contains a modified phosphate group at the 5' position and can be used in the synthesis of oligonucleotides or polynucleotides. This compound is also an antiviral and diphosphate.Degré de pureté :Min. 95%4’-C-Methyl-5-methylcytidine
CAS :<p>4’-C-Methyl-5-methylcytidine is a phosphoramidite nucleoside that is used as a reagent in the synthesis of DNA. It is modified with a 4′-methyl and 5′-methyl group at the C4 and C5 positions of the cytosine base, respectively. The 4′-C methyl group is an antiviral agent that inhibits viral replication by inhibiting reverse transcriptase. The 5′-methyl group prevents deamination of cytosine residues by inhibiting uracil glycosylase. This product has anticancer properties due to its ability to inhibit cell division and activate apoptosis in tumor cells.</p>Degré de pureté :Min. 95%1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt
<p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activities</p>Formule :C35H34FN2O10·C6H16NDegré de pureté :Min. 95%Masse moléculaire :763.87 g/mol6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS :<p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>Formule :C12H17N5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :295.3 g/mol5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine
CAS :<p>5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine is a nucleoside analog that is structurally related to cytidine. It was first synthesized in the 1970s, and has been shown to possess antiviral activity against herpes simplex virus type 1. In addition, it has been shown to inhibit DNA synthesis and the formation of DNA double strands. 5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine is an activator of protein kinase C and cyclic AMP phosphodiesterase, as well as a DNA polymerase inhibitor with anticancer properties.</p>Degré de pureté :Min. 95%2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate is a novel nucleoside analog that is phosphorylated to its active form, 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine monophosphate, which has antiviral and anticancer properties. It can be used as an activator for oligonucleotide synthesis and DNA synthesis. This product is available in high purity (>98%) and high quality. CAS No.: 181297-76-7Degré de pureté :Min. 95%3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine
<p>3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is a phosphoramidite, which is an intermediate in the synthesis of nucleosides. It is a novel deoxyribonucleoside that has been modified to include a methyl group at the 5' position. 3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is often used as an activator for DNA polymerases and ribonucleases, as well as for the synthesis of ribonucleosides. This product has shown anticancer activity by inhibiting RNA synthesis.</p>Degré de pureté :Min. 95%Masse moléculaire :227.22 g/mol4-Demethylwyosine
CAS :<p>4-Demethylwyosine is a metabolite found in the bacterium Pyrococcus furiosus. It is an intermediate in the biosynthesis of 2-amino-3,5-dimethyoxybenzoic acid. 4-Demethylwyosine has been shown to inhibit cancer cell proliferation by inhibiting the synthesis of lysine residues and base formation. This inhibition may be due to its methyl transferase activity, which leads to decreased levels of methionine, or it may be due to its ability to act as a carboxylate group donor. 4-Demethylwyosine has also been shown to bind with DNA and RNA, regulating posttranscriptional processes such as protein translation and transcription.</p>Formule :C13H15N5O5Degré de pureté :Min. 80 Area-%Couleur et forme :PowderMasse moléculaire :321.29 g/mol4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS :4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).Formule :C5H5N5ODegré de pureté :Min. 95%Masse moléculaire :151.13 g/mol3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine
<p>3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside with antiviral and anticancer properties. It is a modified nucleoside that has been synthesized from 2,3'-dideoxycytidine. 3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine has shown to be effective against HIV and influenza virus. 3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine binds to the viral RNA polymerase, preventing the production of viral mRNA. This drug also inhibits DNA synthesis by binding to deoxynucleotide triphosphates (dNTPs) and prevents DNA synthesis by inhibiting the enzyme DNA polymerase.</p>Formule :C23H20N6O5Degré de pureté :Min. 95%Masse moléculaire :460.44 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine
CAS :<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine is a medicament that belongs to the group of antineoplastic agents and is used in cancer treatment. It inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase, which is required for the formation of thymine nucleotides. This drug has been shown to be effective against some cancer cells in vitro and in vivo, but not all. 2'-Deoxy-5'-O-DMT-2'-fluorouridine can also inhibit terminal growth phases and induce programmed cell death. Solid phase synthesis has been used to synthesize this molecule as a phosphoramidite.</p>Formule :C30H29FN2O7Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :548.57 g/mol2',5'-Dideoxyadenosine
CAS :<p>2',5'-Dideoxyadenosine is a nucleotide analog that inhibits the enzyme adenylate cyclase, by binding non-competitively via the P-site</p>Formule :C10H13N5O2Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :235.25 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine
<p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine is a DNA synthesis inhibitor. It is modified with a 2'-deoxy-5'-O-dimethoxytrityl group on the 2' position and an N2,N2-(isobutyryl) guanine moiety on the 5' position. This compound inhibits DNA synthesis by forming a covalent bond to the 3' phosphate of DNA. This product is synthesized in high purity and quality. It can be used for anticancer research or as an activator for phosphoramidites for the synthesis of DNA. CAS No.: 63787-03-6</p>Degré de pureté :Min. 95%2'-Deoxy-N2-DMF-5'-O-tritylguanosine
CAS :<p>2'-Deoxy-N2-DMF-5'-O-tritylguanosine is a nucleoside that is used as a building block in the synthesis of oligonucleotides and other DNA analogues. It is a novel, synthetic nucleoside. The compound has antiviral and anticancer properties. It has been evaluated for use as an activator in antibody production and in the treatment of HIV infection and certain types of cancer. 2'-Deoxy-N2-DMF-5'-O-tritylguanosine is a phosphoramidite, which can be used to synthesize DNA or RNA. This product is available in high purity, diphosphate form and can be used to prepare Anticancer (CAS No. 40094-22-2) Novel Nucleosides (CAS No. 40094-22-2) Phosphoramidites (CAS No. 40094-22</p>Formule :C32H32N6O4Degré de pureté :Min. 95%Masse moléculaire :564.65 g/mol2,6-Dichloro-9-(β-D-ribofuranosyl)purine
CAS :<p>2,6-Dichloro-9-(β-D-ribofuranosyl)purine is a nucleoside analog composed of a modified purine base and a ribose sugar. It has possible applications as an intermediate in nucleoside chemistry, particularly for the synthesis of functionalized purine nucleosides used in biological and pharmaceutical research.</p>Formule :C10H10Cl2N4O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :321.12 g/mol2'-Deoxy-5-methyl-isocytidine triphosphate
<p>2'-Deoxy-5-methyl-isocytidine triphosphate (2'-DMI-dTP) is a novel nucleoside that is synthesized by phosphoramidite chemistry. 2'-DMI-dTP has antiviral and anticancer activities, and can be used for the treatment of hepatitis B virus (HBV) and human papillomavirus (HPV). It has shown protective effects in animal models of HBV infection. 2'-DMI-dTP inhibits HBV replication by inhibiting DNA synthesis. In addition, it decreases levels of reactive oxygen species in cells treated with HBV. 2'-DMI-dTP also inhibits HPV replication through inhibition of DNA synthesis, which may lead to cancer prevention or treatment.<br>2'-DMI-dTP may be a useful drug candidate for the treatment of other viral infections such as influenza A virus and HIV type 1.</p>Degré de pureté :Min. 95%
