Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite
CAS :<p>2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite is a novel, modified nucleoside monophosphate. It is an activator of antiviral and anticancer activities. It is synthesized by the condensation of 5-bromo-2'-deoxyuridine with 2-chloroethyl chloroformate followed by reaction with ethylenediaminetetraacetic acid (EDTA) and sodium cyanoborohydride in aqueous solution. The product was purified by silica gel column chromatography.</p>Formule :C40H47N6O7PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :754.83 g/molCoenzyme A trilithium salt
CAS :<p>Coenzyme A trilithium salt is a synthetic cofactor that is used in the synthesis of long-chain fatty acids. It is membrane permeable and has minimal toxicity, making it an attractive candidate for treating hepatic steatosis. Coenzyme A trilithium salt also activates human mitochondrial beta-oxidation by increasing the availability of substrate and enhancing the expression of genes involved in beta-oxidation. This molecule has been shown to be effective in improving the symptoms of X-linked adrenoleukodystrophy (X-ALD) by stimulating creatine kinase activity and suppressing lysosomal accumulation of long chain fatty acids.</p>Formule :C21H33Li3N7O16P3SDegré de pureté :Min. 80%Couleur et forme :White Off-White PowderMasse moléculaire :785.33 g/mol2-Methoxycarbonyl adenosine
CAS :2-Methoxycarbonyl adenosine is a modified nucleoside and nucleotide. It is an antiviral agent that has been shown to be effective against herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV). 2-Methoxycarbonyl adenosine also has anticancer activity, which may be due to its ability to inhibit DNA synthesis. This agent can also be used as a phosphoramidite for the synthesis of oligonucleotides and as a monophosphate for the synthesis of ribonucleosides. 2-Methoxycarbonyl adenosine is also available in high purity and high quality with CAS No. 70255-70-8.Degré de pureté :Min. 95%2'-Deoxy-2'-fluoroguanosine
CAS :<p>2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.</p>Formule :C10H12FN5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :285.23 g/mol3’-b-C-Methyladenosine
CAS :<p>3’-b-C-Methyladenosine is a novel antiviral and anticancer agent that is synthetically derived from deoxyribonucleosides. 3’-b-C-Methyladenosine has been shown to have antiviral activity against HIV, influenza, herpes simplex virus type 1 and type 2, and vaccinia virus. It also has anticancer activity against leukemia cells. 3’-b-C-Methyladenosine can be used as a phosphoramidite in the synthesis of oligonucleotides. It may be useful as an activator for nucleophilic substitution reactions with phosphorus halides.</p>Degré de pureté :Min. 95%Adenosine 2',3'-cyclic monophosphate sodium
CAS :<p>Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.</p>Formule :C10H11N5NaO6PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :351.19 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine
CAS :2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine is a high purity, novel nucleoside that has antiviral properties. It is a phosphoramidite monophosphate that is synthesized by reacting 5’-O-DMT uridine with bis(2,2,2-trichloroethyl)dimethylsilane and 2,6,8,-trioxabicyclo[3.3.1]nonane in the presence of triethylamine. This product can be used as an activator for DNA synthesis or to synthesize deoxyribonucleosides.Degré de pureté :Min. 95%N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt
CAS :N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt is a monophosphate nucleoside that has been modified with a 6-aminohexylaminocarbonyl group. It is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and proteins. N6-[(6-Aminohexyl)carbamoylmethyl]adenosine 5'-triphosphate lithium salt is novel and high quality.Formule :C18H32N7O14P3·xLiDegré de pureté :Min. 95%2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine
CAS :<p>2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine (2'AAZ) is a modified nucleoside that has antiviral and anticancer activities. This compound blocks the synthesis of DNA, RNA, and proteins. 2'AAZ inhibits cell proliferation by interfering with the replication of DNA and by inhibiting protein synthesis. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. The IC50 values for 2'AAZ are 5 μM for herpes simplex virus type 1 (HSV1) infection in Vero cells, 4 μM for HSV2 infection in Vero cells, 3 μM for influenza A virus (H1N1) infection in MDCK cells, and 0.5 μM for human immunodeficiency virus type 1 (HIV-1) infection in CEM-SS cells.</p>Degré de pureté :Min. 95%5-Iodouridine
CAS :<p>5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.</p>Formule :C9H11IN2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :370.1 g/molThymidine-3',5'-diphosphate sodium salt
CAS :<p>Thymidine-3',5'-diphosphate sodium salt is a nucleoside that is used in the synthesis of oligonucleotides. It is an antiviral and anticancer agent. Thymidine-3',5'-diphosphate sodium salt has been shown to inhibit DNA synthesis, leading to cell death. It also has been shown to be effective against Hepatitis B virus and HIV-1.</p>Formule :C10H16N2O11P2·xNaDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :402.19 g/molN6-Benzoyl-3'-O-methyladenosine
CAS :<p>N6-Benzoyl-3'-O-methyladenosine is a novel modified nucleoside that has antiviral activity. It has been shown to possess high purity and high quality, and can be used as an activator for DNA synthesis. N6-Benzoyl-3'-O-methyladenosine is synthesized from 3'-O-methyladenosine with the use of phosphoramidites, ribonucleosides, or monophosphate nucleotides. The compound is CAS No. 85090-30-8 and is soluble in water.</p>Formule :C18H19N5O5Degré de pureté :Min. 96 Area-%Couleur et forme :Off-White PowderMasse moléculaire :385.37 g/mol2'-Deoxy-4'-thioadenosine
CAS :<p>2'-Deoxy-4'-thioadenosine is a purine nucleoside that is synthesized from 4-thiouridine and phosphorylase. It is cytotoxic and has significant cytotoxicity against cultured cells. The cytotoxicity of 2'-deoxy-4'-thioadenosine was found to be due to its conversion to the triphosphate form in the cells, which inhibits both DNA synthesis and RNA synthesis. This drug also has an inhibitory effect on the growth of tumor cells by inhibiting ribosomal protein synthesis.</p>Formule :C10H13N5O2SDegré de pureté :Min. 95%Masse moléculaire :267.31 g/mol5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS :<p>5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound that has antiviral and anticancer properties. It is synthesized by the reaction of 5,5'-dibromoimidazole with 4,4'-dimethoxytrityl chloride. This product is used as a building block in the synthesis of deoxyribonucleosides, modified phosphoramidites, and nucleosides. It also has high purity and high quality.</p>Degré de pureté :Min. 95%Adenosine 3',5'-diphosphate disodium salt
CAS :<p>Adenosine 3',5'-diphosphate disodium salt is a nucleotide that is found in all cells and is involved in the regulation of many physiological processes, including energy metabolism and blood flow. It has inhibitory effects on platelets and calcium ion channels. Adenosine 3',5'-diphosphate disodium salt also inhibits the synthesis of prostaglandins by blocking the conversion of arachidonic acid to prostaglandin H2, which leads to an anti-inflammatory effect. Adenosine 3',5'-diphosphate disodium salt has been shown to be effective in treating primary pulmonary hypertension and bowel disease. The reaction solution can be used for polymerase chain reactions, multivariate logistic regression, or other applications.</p>Formule :C10H15N5O10P2·2NaDegré de pureté :Min. 96 Area-%Couleur et forme :White Beige PowderMasse moléculaire :473.18 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleotide that can be used for the synthesis of DNA and RNA. It has antiviral, anticancer, and activating properties. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is synthesized by modifying cytosine with an acetyl group at the 4th position in the ribose ring, a tertiary butyldimethylsilyl group at the 2nd position on the 5' carbon atom, and a DMT group at the 5' position on the 5' carbon atom. The CAS number for this compound is 868312050.</p>Degré de pureté :Min. 95%2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine
CAS :<p>2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine (OAAD) is a novel nucleoside that has been modified to be phosphorylated by the enzyme ribonucleotide kinase. It is an antiviral and anticancer agent that affects the synthesis of DNA. OAAD inhibits viral replication in vitro and in vivo by inhibiting DNA synthesis.</p>Formule :C26H23Cl4N5O5Degré de pureté :Min. 95%Masse moléculaire :627.3 g/mol5-Bromo-2'-deoxy-2'-fluorouridine
CAS :<p>5-Bromo-2'-deoxy-2'-fluorouridine is a phosphoramidite that can be used as an anticancer, antiviral, and antimalarial agent. It is modified form of nucleosides with a high purity and quality. It has been shown to have antiviral activity against HIV type 1 and influenza A virus in vitro. 5-Bromo-2'-deoxy-2'-fluorouridine is a novel synthetic nucleoside that binds to the ribonucleotide reductase enzyme and inhibits its activity, which prevents the production of RNA. This drug also has anticancer properties due to its ability to inhibit DNA synthesis by binding to DNA polymerase and blocking the incorporation of deoxythymidylate into DNA. It also has been shown to cause cancer cell death by inhibiting protein synthesis.</p>Degré de pureté :Min. 95%5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
<p>5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has antiviral activity. It is an activator of the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, RNA and proteins. 5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine has shown anticancer activity in several animal models.</p>Degré de pureté :Min. 95%2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt
<p>2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be active against herpes simplex virus type 1 and cytomegalovirus in cell culture. It also inhibits the replication of human immunodeficiency virus type 1 in cell culture. 2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a phosphoramidite nucleoside analog that can be used as an activator for DNA synthesis. It can also serve as a building block for the synthesis of deoxyribonucleosides and ribonucleosides.</p>Degré de pureté :Min. 95%
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