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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • 6-Azacytidine

    CAS :
    6-Azacytidine is a molecule that contains a hydroxyl group and a glycosidic bond. It has been shown to inhibit the growth of mollicutes, which are non-cellular bacteria. 6-Azacytidine has also been shown to be toxic in animal tissue culture studies. The drug can be eliminated through the urine or bile after being metabolized by the liver. 6-Azacytidine is not active against human cells in cell culture, but it does show some toxicity against human liver cells.
    Formule :C8H12N4O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :244.2 g/mol

    Ref: 3D-NA02728

    1mg
    203,00€
    2mg
    344,00€
    5mg
    679,00€
    10mg
    12.545,00€
    100mg
    18.890,00€
  • 1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine

    CAS :
    <p>1-(2'-Deoxy-2'-fluoro-α-L-arabinofuranosyl)-thymine (commonly abbreviated as L-FMAU) is a nucleoside analog. It contains an α-L-arabinofuranose sugar instead of the natural β-D-deoxyribose found in DNA.<br>A fluorine (F) substitution at the 2'-position enhances stability and resistance to enzymatic degradation. The thymine nucleobase allows it to mimic natural thymidine, potentially incorporating into DNA synthesis pathways. It can be research for its potential antiviral activity.</p>
    Formule :C10H13FN2O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :260.22 g/mol

    Ref: 3D-ND58417

    50mg
    135,00€
    100mg
    197,00€
    250mg
    502,00€
    500mg
    764,00€
  • 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine


    <p>2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a nucleoside that is used in the production of DNA and RNA. It is an activator of phosphoramidites, which are used to synthesize oligonucleotides. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can be used as an anti-cancer drug and has antiviral activity. It has been shown to inhibit the replication of HIV by interfering with viral enzymes such as reverse transcriptase and integrase. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can also be used for the treatment of influenza A virus infections. This drug is highly purified, with a high quality, monophosphate form as well as a diphosphate form. There are no known side effects associated with this product.!--</p>
    Formule :C32H30F3N3O8
    Degré de pureté :Min. 95%
    Masse moléculaire :641.61 g/mol

    Ref: 3D-ND08249

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  • 6-Amino-3-iodo-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS :
    <p>6-Amino-3-iodo-4-methoxy-1-(beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and can be used to synthesize DNA and RNA. 6AIOMP binds to the ribonucleotide reductases in cells and inhibits their activity. This prevents the conversion of ribonucleotides into deoxyribonucleotides, which are essential for DNA synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162944

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  • 5’-O-DMT-2’-b-C-methyladenosine


    <p>5’-O-DMT-2’-b-C-methyladenosine is a modified nucleoside with antiviral and anticancer activity. It is an activator of DNA synthesis, and can be used as a precursor for phosphoramidites for the synthesis of oligonucleotides. The 5’-O-DMT group in this compound may be replaced with other activating groups to synthesize different modified nucleosides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND163091

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  • 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine

    CAS :
    <p>3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is a novel synthetic nucleoside that has been shown to have anticancer and antiviral activities. The compound is an activator of the immune system, which may be due to its ability to stimulate the production of interferon and other cytokines. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine can also inhibit viral DNA polymerases. This nucleoside has been shown to inhibit the growth of leukemia cells in culture by inhibiting ribonucleotide reductase activity.</p>
    Formule :C16H29N3O5Si
    Degré de pureté :Min. 95%
    Masse moléculaire :371.51 g/mol

    Ref: 3D-NA09004

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  • 2-Chloro-N6-cyclopentyladenosine hemihydrate

    CAS :
    <p>2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applications</p>
    Formule :C15H20ClN5O4H2O
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :378.81 g/mol

    Ref: 3D-NC07978

    5mg
    229,00€
    10mg
    382,00€
    25mg
    765,00€
    50mg
    1.137,00€
    100mg
    1.444,00€
  • 6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a novel synthetic ribonucleotide that inhibits the growth of tumor cells by interfering with DNA synthesis. This compound has been shown to inhibit the replication of HIV and herpes simplex virus type 1. The phosphoramidite monomer is readily available and can be synthesized in high purity and high quality. 6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is activated by phosphorylation at the 5' position. CAS No.: 10266890</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162982

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  • 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine

    CAS :
    5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a monophosphate nucleoside that inhibits viral replication by inhibiting the synthesis of both DNA and RNA. This compound is used to treat cancers such as leukemia, lymphoma, and multiple myeloma. It also has antiviral properties that are active against herpes simplex virus (HSV) and human cytomegalovirus (CMV). 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a modified nucleoside with a phosphoramidite group on the 2' position of the ribose sugar.
    Formule :C13H14ClN5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White Powder
    Masse moléculaire :355.74 g/mol

    Ref: 3D-NC06333

    25mg
    135,00€
    50mg
    148,00€
  • Pseudothymidine

    CAS :
    <p>Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.</p>
    Formule :C10H14N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :242.23 g/mol

    Ref: 3D-NP16241

    5mg
    274,00€
    10mg
    430,00€
    25mg
    765,00€
    50mg
    1.288,00€
    100mg
    1.932,00€
  • 2,3'-Anhydrouridine 5'-CE phosphoramidite


    2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.
    Formule :C18H27N4O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :426.41 g/mol

    Ref: 3D-PA09084

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  • 3'-O-Aminoacetoxy-2'-deoxycytidine


    Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxycytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Formule :C12H18N4O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :282.30 g/mol

    Ref: 3D-NA180285

    1g
    1.408,00€
    100mg
    262,00€
    500mg
    923,00€
  • 5'-Amino-5'-deoxythymidine

    CAS :
    <p>5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.</p>
    Formule :C10H15N3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :241.24 g/mol

    Ref: 3D-NA06395

    1g
    1.515,00€
    50mg
    254,00€
    100mg
    400,00€
    250mg
    723,00€
    500mg
    1.047,00€
  • 3’-β-Azido-2’,3’-dideoxy-5-fluorouridine

    CAS :
    <p>Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Degré de pureté :Min. 95%

    Ref: 3D-FA144641

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  • 5'-O-Tritylthymidine

    CAS :
    5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.
    Formule :C29H28N2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :484.54 g/mol

    Ref: 3D-NT08062

    1g
    215,00€
    2g
    349,00€
    5g
    538,00€
    250mg
    134,00€
    500mg
    150,00€
  • 5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine


    <p>5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is a modified nucleoside that has been used as an anticancer agent and antiviral and antifungal agent. It has been shown to inhibit the growth of tumor cells in animal models by inhibiting DNA synthesis and repair. 5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is also able to bind to RNA with high affinity, making it a potential candidate for use as an antiviral agent against HIV. This compound does not occur naturally in cells and can be synthesized from other nucleosides.</p>
    Formule :C15H24N2O5Si
    Degré de pureté :Min. 95%
    Masse moléculaire :340.45 g/mol

    Ref: 3D-NB08205

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  • N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite


    <p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is a novel modified nucleoside. It is an antiviral and anticancer agent that has been shown to inhibit the replication of DNA in vitro. It also inhibits the synthesis of RNA and protein, which may contribute to its anti-cancer properties. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is synthesized from 2,6,8 trichloroquinoline and 2,3,4 trimethoxybenzaldehyde via a novel process with high purity.</p>
    Formule :C51H62N7O6PSi
    Degré de pureté :Min. 95%
    Masse moléculaire :928.17 g/mol

    Ref: 3D-PB08713

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  • N4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite


    <p>N4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite is a novel DNA phosphoramidite monomer that has been modified to include an N4-benzoyl group at the 2'-position of the sugar. It is synthesized from 4,5-diaminopyrimidine, 1,3-bis(2-chloroethyl)carbodiimide hydrochloride (EDC), and 4-(N,N-dimethylamino)benzoic acid. The benzoyl group allows for the incorporation of this monomer into DNA in place of deoxycytidine. This product is designed to be used in oligonucleotide synthesis as an activator.</p>
    Formule :C46H51FN5O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :851.9 g/mol

    Ref: 3D-PB57498

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  • 3'-O-Aminoacetoxythymidine


    Amino functionalised thymidine
    Formule :C13H21N4O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :297.33 g/mol

    Ref: 3D-NA180283

    1g
    1.355,00€
    100mg
    262,00€
    500mg
    860,00€
  • N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite


    N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesis
    Formule :C38H52N5O8PSi
    Degré de pureté :Min. 95%
    Masse moléculaire :765.93 g/mol

    Ref: 3D-PB08671

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    À demander