Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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L-Adenosine 5'-monophosphate disodium
CAS :L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.Formule :C10H12N5Na2O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :391.18 g/mol3’-b-C-Methylcytidine
CAS :<p>3’-b-C-Methylcytidine is a nucleoside analog that inhibits the viral enzyme reverse transcriptase and is used as an antiviral agent. 3’-b-C-Methylcytidine binds to DNA and prevents RNA synthesis, which is essential for viral replication. It has been shown to inhibit the growth of cultured cells from human breast cancer and melanoma, suggesting that it also has anticancer activity. 3’-b-C-Methylcytidine can be synthesized in high purity and at high yield using phosphoramidites. This nucleoside analog may be useful in clinical applications due to its ability to activate transcription, which may lead to novel therapeutic strategies.</p>Degré de pureté :Min. 95%5'-Azido-2',5'-dideoxy-2'-fluorouridine
CAS :5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.Formule :C9H10FN5O4Degré de pureté :Min. 95%Masse moléculaire :271.21 g/mol2-Chloro-2',3'-O-isopropylideneadenosine
CAS :2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.Formule :C13H16ClN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.75 g/molClofarabine
CAS :Clofarabine is FDA-approved for treating relapsed or refractory acute lymphoblastic leukaemia (ALL) in children after at least two other types of treatment have failedFormule :C10H11ClFN5O3Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :303.68 g/mol3'-Deoxy-2'-O-methyladenosine
CAS :<p>3'-Deoxy-2'-O-methyladenosine is a nucleoside that has antiviral and anticancer activity. It is a novel chemical compound with a unique structure, which makes it highly reactive. 3'-Deoxy-2'-O-methyladenosine induces DNA synthesis and cell proliferation in cancer cells. It also inhibits the production of viral DNA and RNA in infected cells by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 3'-Deoxy-2'-O-methyladenosine can be used as an antiviral agent against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human cytomegalovirus (CMV).</p>Formule :C11H15N5O3Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :265.27 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS :<p>2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applications</p>Formule :C15H20ClN5O4H2ODegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :378.81 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFormule :C38H52N5O8PSiDegré de pureté :Min. 95%Masse moléculaire :765.93 g/mol6-Thioinosine
CAS :<p>6-Thioinosine is a nucleoside analog that is chemically related to 6-mercaptopurine. It inhibits the polymerase chain reaction and has been shown to inhibit aerobic metabolism in aerobacter aerogenes. It also inhibits the growth of hl-60 cells, which are derived from human leukemia cells. 6-Thioinosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. It also blocks the activity of certain receptors and has a disease activity against infectious diseases such as systemic candidiasis, bacterial endocarditis, and bowel disease.</p>Formule :C10H12N4O4SDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :284.29 g/mol5-b-D-Ribofuranosyl-2(1H)-pyridinone
CAS :<p>5-b-D-Ribofuranosyl-2(1H)-pyridinone is a phosphoramidite that is used in the synthesis of DNA. It is also an antiviral and anticancer agent. 5-b-D-Ribofuranosyl-2(1H)-pyridinone may be modified to include deoxyribonucleosides or ribonucleosides, which are important for DNA synthesis. 5-b-D-Ribofuranosyl-2(1H)-pyridinone is a novel chemical compound with a high purity and quality.<br>5 b D Ribofuranosyl 2 1 H Pyridinone CAS No 188871 50 3 Activator monophosphate High purity High quality DNA Synthetic Deoxyribonucleosides Novel Modified Ribonuclesides Nucleosides</p>Degré de pureté :Min. 95%N2-Isobutyryl-2'-O-methylguanosine
CAS :<p>N2-Isobutyryl-2'-O-methylguanosine (IBOG) is a modified nucleoside that can be used as an activator for DNA synthesis. IBOG is a high purity, high quality chemical with CAS No. 63264-29-9 and has antiviral and anticancer properties.</p>Formule :C15H21N5O6Degré de pureté :Min. 95%Couleur et forme :White To Yellow SolidMasse moléculaire :367.36 g/mol3'-O-Methyladenosine
CAS :<p>3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.</p>Formule :C11H15N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :281.27 g/mol3'-Azido-3'-deoxy-L-uridine
<p>3'-Azido-3'-deoxy-L-uridine is a nucleoside that is a modified form of uridine with an azide group. It has antiviral, anticancer, and novel properties. 3'-Azido-3'-deoxy-L-uridine is synthesized from the corresponding ribonucleosides and diphosphates in high purity and quality. This compound can be used as an antiviral agent in the treatment of AIDS and herpes. It also has anticancer activity, which may be due to its ability to inhibit DNA synthesis or to bind to DNA and induce oxidative stress. 3'-Azido-3'-deoxy-L-uridine is synthesized by the enzymatic conversion of uridines with a monophosphate group at the 3' position into nucleosides with an azide group at the 3' position.</p>Formule :C9H11N5O5Degré de pureté :Min. 95%Masse moléculaire :269.21 g/mol2',5'-Dideoxyguanosine
CAS :<p>2',5'-Dideoxyguanosine is a modified nucleoside analog of guanosine, one of the four natural nucleosides found in RNA and DNA. This synthetic molecule has hydroxyl groups removed from the 2' and 5' positions of the sugar component, which alters its ability to participate in nucleic acid synthesis.</p>Formule :C10H13N5O3Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :251.25 g/molKinetin riboside-5'-diphosphate sodium salt
<p>Kinetin riboside-5'-diphosphate sodium salt is a synthetically modified nucleoside that is used as an activator for DNA synthesis and in the treatment of cancer. Kinetin riboside-5'-diphosphate sodium salt has been shown to have antiviral and anticancer effects, as well as being able to modify the activity of natural substances such as kinetin. This compound has been shown to inhibit tumor growth and reduce the size of some types of tumors in mice. It also inhibits viral replication by blocking viral RNA polymerase activity and inhibiting viral protein synthesis.</p>Degré de pureté :Min. 95%1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil
CAS :<p>1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil is a synthetic antiviral agent that inhibits the activity of DNA and RNA polymerases. It also has anticancer properties. The compound is an analogue of 2'-deoxycytidine monophosphate (dCMP). This compound binds to the phosphate group of nucleoside triphosphates and prevents their incorporation into DNA or RNA. 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy) -2′ fluoro -b D arabinofuranosyl) uracil has been shown to inhibit the growth of cancer cells in vitro.</p>Degré de pureté :Min. 95%BBQ-650-DT CEP
CAS :<p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>Formule :C76H89N12O15PDegré de pureté :Min. 95%Masse moléculaire :1,441.6 g/mol3'-O-Aminoacetoxy-2'-deoxyadenosine
<p>amino functionalised nucleoside</p>Formule :C13H22N6O3Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :310.36 g/molN4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
CAS :N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleoside. It is an activator of DNA and RNA synthesis, which can be used to synthesize deoxyribonucleosides and ribonucleosides. This compound has been shown to have anticancer and antiviral properties. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is also used as a high quality synthetic building block for the synthesis of phosphoramidites.Formule :C48H56N5O9PDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :877.98 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite is a novel monophosphate derivative that is used as an activator for DNA synthesis. This compound is synthesized by reacting 2,4,6-triisopropylbenzenesilyl chloride with 5'-O-tritylthymidine 3'-hydroxyl in the presence of a base. The resulting intermediate is then converted to the desired product with 1,1'-carbonyldiimidazole and 2-(N,N-dimethylamino)ethoxychloroformate.<br>2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite has been shown to be effective against hepatitis B virus and herpes simplex virus type 1 (HSV1).</p>Formule :C44H59N4O7PSiDegré de pureté :Min. 95%Masse moléculaire :815.04 g/mol
