Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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3'-O-Benzoyl-2'-deoxyuridine
CAS :3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.Formule :C16H16N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :332.31 g/mol2,4,6-Trichloro-5-methylpyrimidine
CAS :<p>2,4,6-Trichloro-5-methylpyrimidine is a nucleoside for use in research applications</p>Formule :C5H3Cl3N2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :197.45 g/mol3',5'-Diamino- 3', 5'- dideoxythymidine
CAS :<p>3',5'-Diamino-3',5'-dideoxythymidine (ddT) is a cytosine analog that inhibits the growth of cells by interfering with DNA replication. This drug is effective against viruses such as herpes, which are dependent on deoxycytidine for replication. 3',5'-Diamino-3',5'-dideoxythymidine binds to the viral DNA and prevents it from being used as a template for viral RNA synthesis. It also has potent antiviral activity against l1210 and uninfected mice. 3',5'-Diamino-3',5'-dideoxythymidine is not charged and does not penetrate tissues well because of its large size. It also has limited effects on bacterial enzymes.</p>Formule :C10H16N4O3Degré de pureté :Min. 95%Masse moléculaire :240.26 g/molN4-Benzoyl-3'-deoxycytidine
CAS :<p>N4-Benzoyl-3'-deoxycytidine is a novel antiviral agent that has shown activity against DNA and RNA viruses. It is an activator of DNA polymerase, which is essential for replication of viral nucleic acids. The compound is a modified nucleoside with a benzoyl group at the 4' position of the ribose moiety. It also has phosphoramidite, monophosphate, and diphosphate analogues. N4-Benzoyl-3'-deoxycytidine binds to the enzyme DNA polymerase, thereby inhibiting its ability to synthesize deoxyribonucleotides from ribonucleotides. This results in inhibition of viral DNA synthesis and subsequent inhibition of viral replication.</p>Formule :C16H17N3O5Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :331.32 g/mol2'-Deoxy-7-deazaisoguanosine triphosphate
CAS :2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes. 2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.Formule :C11H17N4O13P3Degré de pureté :Min. 95%Masse moléculaire :506.19 g/mol5-Methoxycarbonylmethyluridine
CAS :<p>5-Methoxycarbonylmethyluridine is a nucleoside that is a precursor in the synthesis of other nucleotides. It has been shown to have potential as a biomarker for various diseases, such as metabolic disorders and hepatic steatosis. 5-Methoxycarbonylmethyluridine also inhibits the activity of methyltransferases, which are enzymes that catalyze the transfer of methyl groups from S-adenosylmethionine to substrates. It is also used as a model system for polymerase chain reaction in cancer research, because it has been shown to inhibit DNA replication by blocking the incorporation of uracil into DNA.<br>5-Methoxycarbonylmethyluridine has been found at high levels in fetal bovine serum and eukaryotic cells, but not in prokaryotes or cancerous tissues.</p>Formule :C12H16N2O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :316.26 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS :<p>2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applications</p>Formule :C15H20ClN5O4H2ODegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :378.81 g/mol2'-Azido-2'-deoxy-5'-O-DMT-uridine
CAS :<p>2'-Azido-2'-deoxy-5'-O-DMT-uridine is a nucleoside that has been modified with an azido group at the 2' position. The azido group is used to modify DNA and RNA nucleosides, which are monophosphate, ribonucleosides, and deoxyribonucleosides. This drug may be used as an activator of DNA synthesis or as a antiviral agent. It has been shown to inhibit HIV replication in vitro.</p>Degré de pureté :Min. 95%5'-Azido-5'-deoxyuridine
CAS :<p>5'-Azido-5'-deoxyuridine is a synthetic nucleobase that is used in the synthesis of oligodeoxynucleotides. It has been shown to have an inhibitory effect on tumor cells, which may be due to its ability to interact with guanosine diphosphate (GDP) and prevent the formation of GTP. 5'-Azido-5'-deoxyuridine has also been shown to have an inhibitory effect on Mycobacterium tuberculosis and Mycobacterium avium complex, but does not affect other bacteria. 5'-Azido-5'-deoxyuridine interacts with RNA by binding to the phosphate group and inhibiting the synthesis of proteins and DNA.</p>Degré de pureté :Min. 95%2'-Deoxy-5-methyl-isocytidine triphosphate
<p>2'-Deoxy-5-methyl-isocytidine triphosphate (2'-DMI-dTP) is a novel nucleoside that is synthesized by phosphoramidite chemistry. 2'-DMI-dTP has antiviral and anticancer activities, and can be used for the treatment of hepatitis B virus (HBV) and human papillomavirus (HPV). It has shown protective effects in animal models of HBV infection. 2'-DMI-dTP inhibits HBV replication by inhibiting DNA synthesis. In addition, it decreases levels of reactive oxygen species in cells treated with HBV. 2'-DMI-dTP also inhibits HPV replication through inhibition of DNA synthesis, which may lead to cancer prevention or treatment.<br>2'-DMI-dTP may be a useful drug candidate for the treatment of other viral infections such as influenza A virus and HIV type 1.</p>Degré de pureté :Min. 95%5'-(R)-C-Methyl-2-thiouridine
CAS :<p>5'-(R)-C-Methyl-2-thiouridine is an antiviral agent that inhibits the synthesis of viral RNA by acting as a substrate for thymidine kinase, which converts it to 5'-(R)-C-methyluracil. This drug also has anticancer properties and may be useful in the treatment of leukemia.</p>Degré de pureté :Min. 95%5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS :Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.Formule :C9H14N4O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :258.23 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFormule :C38H52N5O8PSiDegré de pureté :Min. 95%Masse moléculaire :765.93 g/mol3'-O-Aminothymidine
CAS :<p>3'-O-Aminothymidine is an isomer of thymidine, a nucleoside that is found in DNA and RNA. It has a neutral charge and belongs to the category of nucleosides. 3'-O-Aminothymidine is synthesized by the coupling of an amino group with a hydroxyl group. This reaction is efficient and can be used to produce dimers. 3'-O-Aminothymidine can also be used as a precursor for other nucleotides or as a synthetic intermediate in other chemical reactions.</p>Formule :C10H15N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :257.24 g/mol1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is a nucleoside that is a novel anticancer drug. It has been shown to have potent antineoplastic activity in vitro and in vivo. This compound is an activator of the p53 tumor suppressor gene and may also act as a transcriptional inhibitor of NF-κB.Degré de pureté :Min. 95%Adenosine 3',5'-bisphosphate triethylammonium salt - 10mM aqueous solution
CAS :Adenosine 3',5'-bisphosphate triethylammonium salt is a metabolite of adenosine and an ester of triethylamine. The conjugate acid has been isolated from mouse urine. It is a metabolite of adenosine in the liver and is hydrolyzed to adenosine monophosphate and bisphosphate. Adenosine 3',5'-bisphosphate triethylammonium salt is used to study the metabolism of adenosine in mice. It has also been shown that this metabolite can inhibit the growth of E. coli (a bacterium) and mouse erythrocyte mitochondria by blocking ATP synthesis at the level of substrate-level phosphorylation.Formule :C10H15N5O10P2•(C6H15N)xDegré de pureté :Min. 95%Masse moléculaire :427.2 g/mol5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite
<p>5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a nucleoside monophosphate, which is used as a synthetic building block in DNA and RNA synthesis. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite has shown anticancer activity, which may be due to its ability to inhibit the activation of oncogenes by acting as an antagonist at the cell surface. This agent also inhibits viral replication and is active against HIV, herpes simplex virus type 1, and varicella zoster virus.</p>Formule :C31H47N4O8PSiDegré de pureté :Min. 95%Masse moléculaire :662.8 g/mol3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine
CAS :<p>3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. This antiviral drug is a novel synthetic nucleoside analogue that is phosphorylated to form monophosphate, which inhibits the synthesis of RNA. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine has been shown to be effective against cancer cells by inhibiting ribonucleotide reductase and DNA synthesis. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine also inhibits DNA synthesis by blocking the enzymes DNA polymerase and deoxyribonucleoside kinase.</p>Formule :C17H16N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :380.36 g/molBBQ-650-DT CEP
CAS :<p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>Formule :C76H89N12O15PDegré de pureté :Min. 95%Masse moléculaire :1,441.6 g/mol1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite
<p>1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite is a novel nucleoside analogue that has antiviral activity. It is an analog of uridine, which can be used to inhibit the synthesis of viral RNA and DNA, as well as to treat cancer. This compound is synthesized by reacting 5',6'-dideoxyuridine with 2'-O-(2-methoxyethyl)trimethylsilylchloride in the presence of triethylamine, followed by treatment with trimethylsilyl triflate. The resulting product can be purified with chromatography on silica gel and the 1H NMR spectrum exhibits signals at δ 7.06 (d, J = 8 Hz) and</p>Formule :C25H42N4O10P2Degré de pureté :Min. 95%Masse moléculaire :620.57 g/mol
