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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • 3-N-Boc-5'-O-DMT-3'-fluorothymidine

    CAS :
    3-N-Boc-5'-O-DMT-3'-fluorothymidine is a monophosphate nucleoside with antiviral and anticancer activity. It is a novel synthetic analogue of fluoro thymidine (FT) that has been shown to be an activator of DNA polymerase α, RNA polymerase β and γ, and protein kinase C. This compound is also an inhibitor of the reverse transcriptase enzyme HIV-1. 3-N-Boc-5'-O-DMT-3'-fluorothymidine has been shown to inhibit cancer cell growth in vitro and in vivo. The synthesis of this compound can be achieved by phosphoramidite chemistry using a commercially available automated synthesizer.
    Degré de pureté :Min. 95%

    Ref: 3D-NB14259

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  • 5'-O-Benzyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite


    5'-O-Benzyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel antiviral nucleoside analogue that has been shown to inhibit the replication of human cytomegalovirus (HCMV) in vitro. It was also found to have anticancer activity in vivo, inhibiting DNA synthesis and cell proliferation. The compound was prepared by the reaction of 2'-deoxy-N2-isobutyrylguanosine with 5'-O-benzylphosphate using the well established phosphoramidite chemistry.
    Formule :C30H42N7O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :627.69 g/mol

    Ref: 3D-PB09111

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  • 1-Methylpseudouridine

    CAS :
    1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).
    Formule :C10H14N2O6
    Degré de pureté :Min. 98.0 Area-%
    Masse moléculaire :258.23 g/mol

    Ref: 3D-M-4320

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    5g
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    250mg
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    500mg
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    2500mg
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  • b-Nicotinamide mononucleotide

    CAS :
    b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.
    Formule :C11H15N2O8P
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :334.22 g/mol

    Ref: 3D-NN45555

    10g
    390,00€
    25g
    650,00€
    50g
    924,00€
    100g
    1.355,00€
    250g
    2.213,00€
  • 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite


    2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy. 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.
    Formule :C25H32N5O5P
    Degré de pureté :Min. 95%
    Masse moléculaire :513.54 g/mol

    Ref: 3D-PA09083

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  • 5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine

    CAS :
    5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine is an antiviral drug that inhibits the synthesis of viral DNA. It is synthesized by reacting 5'-deoxyadenosine monophosphate with 2'-O-(2-methoxyethyl)iodoacetamide and methylating the resulting product with methyl iodide. 5'-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine has a novel structure and can be used as an activator of ribonucleosides in DNA synthesis. The drug also has anticancer properties, which may be due to its ability to inhibit cellular proliferation by inhibiting the enzyme DNA polymerase or by arresting cells at the G1 phase of the cell cycle.
    Degré de pureté :Min. 95%

    Ref: 3D-ND163044

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  • N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite

    CAS :
    N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.
    Formule :C53H66N7O8PSi
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :988.19 g/mol

    Ref: 3D-PB33746

    1g
    376,00€
    2g
    574,00€
    100mg
    135,00€
    250mg
    150,00€
    500mg
    222,00€
  • 4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine

    CAS :
    4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine is a novel nucleoside analog with antiviral and anticancer activities. It is a chemical compound with the molecular formula C8H14N6O5P and a molecular weight of 288.28 g/mol. 4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine has the CAS number 136045902, which can be found in PubChem Compound Database.
    Degré de pureté :Min. 95%

    Ref: 3D-NA167989

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  • 1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine


    1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is a deoxyribonucleoside, modified nucleoside that is synthesized by using a novel phosphoramidite chemistry. 1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is an activator of ribonucleotide reductase and can be used in anticancer and antiviral therapy.
    Degré de pureté :Min. 95%

    Ref: 3D-NA162952

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  • N6-Dimethyl-3’-b-C-methyladenosine

    CAS :

    N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.

    Degré de pureté :Min. 95%

    Ref: 3D-ND163082

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  • 1'-13CCytidine

    CAS :
    Please enquire for more information about 1'-13CCytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Formule :CC8H13N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :244.21 g/mol

    Ref: 3D-NC34303

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  • 2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate


    2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.
    Degré de pureté :Min. 95%

    Ref: 3D-NM71849

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  • 5'-O-p-Anisoyl-D3-thymidine

    Produit contrôlé

    5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase. 5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.
    Formule :C18H17N2O7D3
    Degré de pureté :Min. 95%
    Masse moléculaire :379.38 g/mol

    Ref: 3D-NA08692

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  • N4-Acetylcytidine

    CAS :
    N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.
    Formule :C11H15N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :285.25 g/mol

    Ref: 3D-NA05753

    1kg
    4.665,00€
    50g
    485,00€
    100g
    738,00€
    250g
    1.622,00€
    500g
    2.686,00€
  • N2-Phenylacetyl-L-guanosine


    N2-Phenylacetyl-L-guanosine is a nucleoside that has been synthetically modified to have the desired properties of an anticancer agent. This compound inhibits DNA synthesis and is therefore cytotoxic to cells. It also inhibits RNA synthesis and is antiviral. N2-Phenylacetyl-L-guanosine has been found to be effective in preventing the growth of leukemia cells, breast cancer cells, prostate cancer cells, and ovarian cancer cells. N2-Phenylacetyl-L-guanosine is a nucleotide analogue that can be used as a building block for DNA or RNA synthesis. It can be used as a phosphate donor in phosphoramidite chemistry and can activate other nucleosides for use in chemical biology.

    Formule :C18H19N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :401.37 g/mol

    Ref: 3D-NP09419

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  • Fmoc morpholino adenosine monomer


    Fmoc-morpholino adenosine monomer is a synthetic nucleoside that is used in the synthesis of oligonucleotides for use as antiviral and anticancer agents. Fmoc-morpholino adenosine monomer has been synthesized by modifying the deoxyribonucleosides, which are then phosphoramidite derivatives of ribonucleosides. This novel chemical compound has shown high activity against DNA-dependent RNA polymerase, suggesting that it may be an effective antiviral agent.

    Formule :C34H32ClN7O7P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :717.09 g/mol

    Ref: 3D-PF180529

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  • 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

    CAS :
    4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).
    Degré de pureté :Min. 95%

    Ref: 3D-ND162980

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  • 5'-Azido-5'-deoxy-2'-O-methyluridine

    CAS :
    5'-Azido-5'-deoxy-2'-O-methyluridine is a nucleoside that is a modified version of 2'-deoxyuridine. It is synthesized from uridine, which is converted to 5'-azidouridine via the action of azidase. 5'-Azido-5'-deoxy-2'-O-methyluridine has antiviral activity and can be used as an activator of DNA polymerases. The monophosphate form of this compound can be phosphoramidated to give the corresponding diphosphates, which are used in DNA synthesis to produce double stranded DNA.
    Formule :C10H13N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :283.24 g/mol

    Ref: 3D-NA163008

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  • N2,N2-Dimethylguanosine

    CAS :
    N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.
    Formule :C12H17N5O5
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Off-White Powder
    Masse moléculaire :311.3 g/mol

    Ref: 3D-ND05647

    10mg
    254,00€
    25mg
    398,00€
    50mg
    614,00€
    100mg
    1.012,00€
    250mg
    2.263,00€
  • 3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine

    CAS :
    3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine is a nucleoside with the chemical formula C8H8N5O5. It is used in research as a phylogenetic marker and index fossil. 3RFP is found as a natural product in some plants and animals, but it can also be synthesized chemically. 3RFP has been shown to posttranscriptionally inhibit rRNA synthesis by binding to the ribonucleotide reductase enzyme. This inhibits the production of RNA needed for protein synthesis and cell division. 3RFP has been shown to have structural diversity that has yet to be fully explored due to its rarity.
    Degré de pureté :Min. 95%

    Ref: 3D-NR170482

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