Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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3'-O-Aminoacetoxy-2'-deoxyguanosine
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Formule :C13H17N6O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :321.32 g/molb-Nicotinamide adenine dinucleotide phosphate sodium salt
CAS :Coenzyme and regenerating electron donor in catabolic processesFormule :C21H27N7NaO17P3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :765.39 g/molL-Adenosine 5'-monophosphate disodium
CAS :L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.Formule :C10H12N5Na2O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :391.18 g/mol2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil
CAS :2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a novel and high purity anticancer and antiviral agent. It is an activator that has been shown to exhibit antineoplastic activity in vitro. The compound also inhibits the formation of RNA and DNA, which are necessary for the replication of cells. 2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a modified nucleoside that has been synthesized by phosphoramidite chemistry. This product can be used for research purposes and as a starting material for the synthesis of other compounds with similar structures.Formule :C11H12N2O7Degré de pureté :Min. 95%Masse moléculaire :284.22 g/mol3’-b-C-Methylcytidine
CAS :3’-b-C-Methylcytidine is a nucleoside analog that inhibits the viral enzyme reverse transcriptase and is used as an antiviral agent. 3’-b-C-Methylcytidine binds to DNA and prevents RNA synthesis, which is essential for viral replication. It has been shown to inhibit the growth of cultured cells from human breast cancer and melanoma, suggesting that it also has anticancer activity. 3’-b-C-Methylcytidine can be synthesized in high purity and at high yield using phosphoramidites. This nucleoside analog may be useful in clinical applications due to its ability to activate transcription, which may lead to novel therapeutic strategies.Degré de pureté :Min. 95%5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
CAS :5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine is an antiviral agent that can be used in combination with other drugs to treat HIV infection. It has been shown to inhibit the activity of p450 enzymes and to bind to receptor sites on cells, preventing the virus from replicating. 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine has been tested in clinical studies for its ability to reduce levels of HIV in people infected with this virus. This compound also has immunomodulatory effects, which may be due to its ability to inhibit replication of the herpes simplex virus.Formule :C9H10FN3O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :227.19 g/mol5'-Azido-2',5'-dideoxy-2'-fluorouridine
CAS :5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.Formule :C9H10FN5O4Degré de pureté :Min. 95%Masse moléculaire :271.21 g/molb-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)
CAS :b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathioneFormule :C21H30N7O17P3·4C6H13NDegré de pureté :Min. 90 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :1,142.12 g/mol2-Chloro-2',3'-O-isopropylideneadenosine
CAS :2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.Formule :C13H16ClN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.75 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine
CAS :3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine is a deoxyribonucleoside that is chemically modified to be resistant to nucleases. It is used as an antiviral agent and activates the immune system by inducing cytokines, chemokines, and interferons. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine has been shown to have antidepressant effects in mice and rats. This drug also has been shown to inhibit the production of HIV viral particles in vitro.Formule :C41H51N5O8SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :769.96 g/molRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS :Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.Formule :C8H15N4O14P3·Na4Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :576.1 g/mol3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine
3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that inhibits DNA synthesis by competitively inhibiting the activity of deoxycytidine kinase. 3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is an antiviral agent and has been shown to be effective against herpes simplex virus type 1 and varicella zoster virus. It has also been shown to have anticancer properties, which may be due to its ability to inhibit the growth of human breast cancer cells in culture.Formule :C24H24N4O6Degré de pureté :Min. 95%Masse moléculaire :464.47 g/mol3'-Deoxy-2'-O-methyladenosine
CAS :3'-Deoxy-2'-O-methyladenosine is a nucleoside that has antiviral and anticancer activity. It is a novel chemical compound with a unique structure, which makes it highly reactive. 3'-Deoxy-2'-O-methyladenosine induces DNA synthesis and cell proliferation in cancer cells. It also inhibits the production of viral DNA and RNA in infected cells by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 3'-Deoxy-2'-O-methyladenosine can be used as an antiviral agent against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human cytomegalovirus (CMV).
Formule :C11H15N5O3Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :265.27 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine
CAS :2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine is a modified nucleoside that is used as an anticancer drug. It is synthesized from 2’,3’,5’triphosphate and 2’C-methyl-5-methoxyuridine. This compound is used to treat leukemia and other cancers by inhibiting the synthesis of DNA. Inhibiting DNA synthesis prevents the reproduction of cancer cells. The chemical structure of this compound was first published in 2007.Degré de pureté :Min. 95%5-(2-Fluorovinyl)-2'-Deoxyuridine
CAS :5-(2-Fluorovinyl)-2'-Deoxyuridine is a hydrophobic analogue of acyclovir that has potent activity against herpes simplex virus type 1. It inhibits the synthesis of viral DNA, and thus prevents the formation of plaques in tissue culture. This drug also inhibits cell proliferation and viral production by l1210 cells as well as lung fibroblasts. 5-(2-Fluorovinyl)-2'-Deoxyuridine has shown inhibitory effects against uninfected cells, but not against cells infected with herpes simplex virus type 2.Formule :C11H13FN2O5Degré de pureté :Min. 95%Masse moléculaire :272.23 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS :N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.
Formule :C20H21N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :411.41 g/mol2'-O-(2-Methoxyethyl)uridine
CAS :2'-O-(2-Methoxyethyl)uridine is a nucleoside analog that inhibits the synthesis of DNA, RNA and protein. It can be used as an antimetabolite to treat cancer and prevents tumor growth by interfering with cell division. 2'-O-(2-Methoxyethyl)uridine is often used in combination with other chemotherapeutic drugs. This drug is not active against bacteria and does not inhibit the growth of bacteria. The major disadvantage of this drug is its lack of efficacy against tumors, which may be due to the lack of penetration through the cell membrane or damage to DNA caused by radiation, abiotic factors, or malfunctioning enzymes. 2'-O-(2-Methoxyethyl)uridine has been shown to cause damage to cells by altering their metabolism and affecting the function of their mitochondria. Damage can cause cells to die through apoptosis or necrosis.Formule :C12H18N2O7Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :302.28 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS :2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a purine nucleoside where the purine base has a 2-amino group at position 2 and a chlorine at position 6. The sugar is 2'-deoxy, meaning it is like the sugar found in DNA, lacking the 2'-hydroxyl group that is present in RNA. The amino and chloro groups on the purine base modify how this molecule behaves in biological systems making it useful in research applications.Formule :C10H12ClN5O3Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :285.69 g/mol4-Thiouridine
CAS :4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analogue that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labelling. 4-SU is typically used to modify RNA oligonucleotides, or in structure studies of RNA-protein complexes. The crosslinking thiol moiety is attached directly to the nucleotide base, thus 4-SU differs from the nucleoside uridine only by a single sulfur substitution. This means it can be incorporated into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will significantly impair RNA interactions or activities.Formule :C9H12N2O5SDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :260.27 g/mol5'-O-p-Anisoyl-3'-fluoro-2',3'-dideoxyuridine
5'-O-p-Anisoyl-3'-fluoro-2',3'-dideoxyuridine (5-FAU) is a deoxynucleoside that is synthesized by the phosphoramidite method, and it has been used as an antiviral agent. 5-FAU is a novel nucleoside analog with anticancer activity. It inhibits replication of herpes simplex virus type 1 and 2, varicella zoster virus, and Epstein Barr virus in cell culture. 5-FAU also inhibits HIV replication in vitro and in animal models. The antiviral activity of 5-FAU is due to its inhibition of viral DNA polymerase, which prevents the synthesis of viral DNA from viral RNA templates.Formule :C17H17FN2O6Degré de pureté :Min. 95%Masse moléculaire :364.33 g/mol
