Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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Pseudothymidine
CAS :Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.Formule :C10H14N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :242.23 g/molN6-Benzoyl-2'-C-methyladenosine
N6-Benzoyl-2'-C-methyladenosine is synthetic and has antiviral properties. It is a nucleoside that belongs to the group of modified nucleosides. This compound can be used as an activator for DNA synthesis and as a novel monophosphate, diphosphate, or triphosphate. N6-Benzoyl-2'-C-methyladenosine is also available in high purity, with CAS No., and at a competitive price.Degré de pureté :Min. 95%2,3'-Anhydrouridine 5'-CE phosphoramidite
2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.Formule :C18H27N4O6PDegré de pureté :Min. 95%Masse moléculaire :426.41 g/molGuanosine 3',5'-cyclic monophosphate sodium salt
CAS :Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP) is a cyclic nucleotide that is involved in the regulation of many cellular processes. It binds to specific guanine nucleotide-binding proteins (G proteins) and activates protein kinase A, which regulates glucose metabolism and energy production. cGMP also affects neuronal death, axonal growth, and bowel disease by acting as a cyclase inhibitor or activating the immune system. It has been shown to reduce the severity of infectious diseases such as HIV and malaria by activating the immune system.Formule :C10H11N5NaO7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.19 g/mol3'-O-Aminoacetoxy-2'-deoxycytidine
Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxycytidine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C12H18N4O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :282.30 g/mol8-Azidoadenosine
CAS :8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.
Formule :C10H12N8O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :308.25 g/mol5'-Amino-5'-deoxythymidine
CAS :5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.Formule :C10H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :241.24 g/mol3'-Deoxyguanosine
CAS :3'-Deoxyguanosine is a nucleic acid that is involved in the synthesis of polysaccharides and proteins. It has been shown to have an inhibitory effect on the synthesis of collagen, which may be due to its ability to increase hydrogen bonding between the nitrogen atoms and oxygen atoms. 3'-Deoxyguanosine has also been shown to have a protective effect on wheat germ extract, which may be due to its ability to inhibit oxidation reactions. The chemical structure of 3'-deoxyguanosine can be synthesized by reacting deoxyribose with sodium nitrate in the presence of sulfuric acid. This reaction can be monitored using electrochemical impedance spectroscopy (EIS).Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :267.25 g/mol3’-β-Azido-2’,3’-dideoxy-5-fluorouridine
CAS :Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Degré de pureté :Min. 95%CTP 2Na
CAS :CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.Formule :C9H14N3Na2O14P3Degré de pureté :Min. 95.0 Area-%Couleur et forme :White PowderMasse moléculaire :527.12 g/mol5'-O-Tritylthymidine
CAS :5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.Formule :C29H28N2O5Degré de pureté :Min. 95%Masse moléculaire :484.54 g/mol5'-O-Benzoyl-2'-O-tert-butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-O-tert-butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is a modified nucleoside analog that can be used in the synthesis of DNA, RNA and other nucleic acids. It has been shown to inhibit cancer cells and viruses. The compound is an activator of the human immunodeficiency virus type 1 reverse transcriptase and also inhibits the replication of Herpes simplex virus type 1. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is stable in both acidic and basic conditions, making it suitable for use in various chemical reactions.Formule :C36H54N7O8PSiDegré de pureté :Min. 95%Masse moléculaire :771.92 g/mol2'-Deoxyuridine-5'-triphosphate trisodium
CAS :2'-Deoxyuridine-5'-triphosphate trisodium salt is a fluorophore that is excited by the absorption of light at wavelengths of 365 nm. The emission spectrum ranges from 380 to 500 nm and has a maximum at 480 nm. 2'-Deoxyuridine-5'-triphosphate trisodium salt can be used as a labeling agent for metal ion, molecule, or macrocyclic ligand. It can also be used as an acceptor in fluorescence energy transfer experiments.Formule :C9H15N2O14P3•Na3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :537.11 g/molClofarabine 5'-triphosphate triethylammonium salt
CAS :Clofarabine is a nucleoside analog that is used to treat various types of cancer, including leukemia, lymphoma, and solid tumours. Clofarabine has been shown to have minimal toxicity in healthy cells and is usually well tolerated by patients. It acts by inhibiting the synthesis of DNA in rapidly dividing cells. This effect can be synergistic with other anti-cancer agents such as the cytotoxic agent Bleomycin. Clofarabine binds to an intracellular target and inhibits DNA synthesis by blocking the enzyme DNA polymerase. Inhibition of this enzyme leads to cell death. Clofarabine has been tested in pediatric patients from age 1 month old up to 18 years old. The drug has been found to be safe for use in this population.Formule :C10H14ClFN5O12P3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :543.62 g/molN3-Methyl-2'-O-methyluridine
CAS :2'-O-methyluridine is an antiviral nucleoside that is used as a phosphoramidite in the synthesis of oligonucleotides. It has been shown to inhibit viral replication, and has been found to be effective in treating HIV-1 by inhibiting reverse transcriptase. N3-Methyl-2'-O-methyluridine also inhibits DNA synthesis and cell proliferation, and may be useful for the treatment of cancer. This modified nucleoside has been synthesized from uracil and contains a methyl group at the 3' position. The methyl group prevents 2'-O-methyluridine from being activated by cellular thymidylate synthase, which normally converts deoxyribonucleotides into ribonucleotides. This novel nucleotide has not yet been used in clinical trials but it may provide an alternative to other drugs used for cancer treatments.
Formule :C11H16N2O6Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :272.25 g/mol3’-Bromo-2’,3’-dideoxy-5-methyluridine
CAS :3’-Bromo-2’,3’-dideoxy-5-methyluridine is a nucleoside analog that is an antiviral agent. It has been shown to inhibit HIV in vitro and in animal models. It is active against HIV isolates that are resistant to other nucleoside analogs, such as zalcitabine. 3’-Bromo-2’,3’-dideoxy-5-methyluridine inhibits the viral RNA polymerase and DNA polymerase of the virus by competing with natural substrates for binding sites on these enzymes. This inhibition prevents the production of new viral RNA and DNA and can lead to a decrease in the amount of viral particles found in blood, lymphatic tissues, and cerebrospinal fluid.Degré de pureté :Min. 95%3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine
CAS :3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine is a modified nucleoside that can be used as an antiviral agent. It is a phosphoramidite that is activated by diphosphate and has been shown to inhibit DNA replication in vitro. 3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine also has anticancer activity and can be used to treat leukemia, lymphoma, and myeloma. This high quality product is synthesized from natural deoxyribonucleosides and has a purity of > 98%.Formule :C16H21N5O6Degré de pureté :Min. 95%Masse moléculaire :379.37 g/mol2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine
2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.Degré de pureté :Min. 95%5'-Amino-5'-deoxyadenosine hydrochloride
CAS :5'-Amino-5'-deoxyadenosine hydrochloride (5'-ADeA) is a nucleotide that is synthesized from ribose 5-phosphate and adenosine monophosphate. It has been shown to have potential as a biomarker for skin cancer. The synthesis of 5'-ADeA is catalyzed by the enzyme caffeic acid 4-monooxygenase, which converts caffeic acid into 5'-ADeA. This reaction requires molecular oxygen, NADPH, and iron ions. The activity of this enzyme can be inhibited by sodium carbonate or basic fibroblast growth factor (bFGF). This drug has been shown to have anti-inflammatory effects in vivo.Formule :C10H14N6O3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :266.26 g/mol7-Deaza-4-Cl-2'-deoxyguanosine
CAS :7-Deaza-4-Cl-2'-deoxyguanosine is a novel antiviral drug that has been synthesized in the laboratory. It is an analogue of deoxyguanosine, a nucleoside that is found in DNA and RNA. 7-Deaza-4-Cl-2'-deoxyguanosine has anti cancer properties because it inhibits the synthesis of DNA by inhibiting the activity of ribonucleoside reductase, an enzyme that converts ribonucleosides to deoxyribonucleosides. This drug has been shown to have potent anticancer activity against human lung cancer cells and mouse leukemia cells.Formule :C11H13ClN4O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :284.7 g/mol
